ライフサイエンスコーパス: v-Akt

1 The increased kinase activity of v-akt, an oncogenic form of Akt/PKB, causes mouse T cell

2 v-Abl Delta858-1080 was rescued by activated v-Akt and was also moderately rescued by activated v-H-R

3 COMMA-1D/tv-a cells transduced with RCAS/v-akt, but not RCAS/Akt1, formed anchorage-independent c

4 into the medium by COMMA-1D/Akt1 or COMMA-1D/v-akt cells revealed elevated gelatinase activity that w

5 ivity and invasion associated with Akt1- and v-akt-expressing cells.

6 vasion in control cells but not in Akt1- and v-akt-expressing cells.

7 Constitutively active v-AKT highly phosphorylated p70S6K, which was totally in

8 Constitutive expression of v-Akt likewise enhanced survival of H(2)O(2)-treated NIH

9 v akt murine thymoma viral oncogene homolog (AKT) regula

10 isome proliferator-activated receptor gamma, v-AKT murine thymoma oncogene homolog 2, zinc metallopro

11 led to an increase in the phosphorylation of v-AKT murine thymoma viral oncogene (AKT) and enhanced t

12 bination of oncogenic forms of activation of v-akt murine thymoma viral oncogene homolog (AKT) and NR

13 Activation of v-akt murine thymoma viral oncogene homolog (AKT) and Ra

14 Concomitant expression of activated forms of v-akt murine thymoma viral oncogene homolog (AKT) and Ra

15 racellular signal-regulated kinase (ERK) and v-akt murine thymoma viral oncogene homolog (AKT) in a s

16 tes the phosphatidylinositol 3-kinase (PI3K)/v-AKT murine thymoma viral oncogene homolog (AKT) pathwa

17 The protein kinase v-akt murine thymoma viral oncogene homolog (AKT), a key

18 I3K), phosphatase and tensin homolog (PTEN), v-akt murine thymoma viral oncogene homolog (AKT), and m

19 The kinase v-akt murine thymoma viral oncogene homolog 1 (Akt) and

20 Inhibition of PIK3CA by miR-10a reduced V-akt murine thymoma viral oncogene homolog 1 (AKT) phos

21 PP2A is a major negative regulator of v-akt murine thymoma viral oncogene homolog 1 (AKT).

22 Activated v-AKT murine thymoma viral oncogene homolog 1 (AKT)/prot

23 gulator of G-protein signalling 4 (RGS4) and V-AKT murine thymoma viral oncogene homolog 1 (AKT1) the

24 plex 1 (RAPTOR), the serine/threonine kinase V-Akt murine thymoma viral oncogene homolog 1 (AKT1), an

25 The proline-rich Akt (v-akt murine thymoma viral oncogene homolog 1) substrate

26 720 and induced hyperphosphorylation of AKT (v-akt murine thymoma viral oncogene homolog 1), a phenot

27 ouse model of primary liver cancer driven by v-akt murine thymoma viral oncogene homolog and neurobla

28 metinib indicated a compensatory increase in v-akt murine thymoma viral oncogene homolog signaling an

29 gh expression of miR-155 sensitizes cells to v-akt murine thymoma viral oncogene homolog-1 inhibitors

30 ery of tau kinases such as protein kinase A, v-Akt murine thymoma viral oncogene homolog-1, glycogen

31 a integrin-beta1, protein kinase C-zeta, and v-akt murine thymoma viral oncogene homolog.

32 ed the role of the phosphoinositide-3-kinase/v-akt murine thymoma viral oncogene homolog/mammalian ta

33 d the metabolic and growth properties of the v-akt murine thymoma viral oncogene homolog/mammalian ta

34 Consistent with this suggestion, v-akt murine thymoma viral oncogene homolog/protein kina

35 Although AKT1 (v-akt murine thymoma viral oncogene homologue 1) kinase

36 noma cells inhibits the HGF-induced MET-AKT (v-Akt murine thymoma viral oncogene) signaling pathway a

37 showed hypertrophic signaling (activation of v-akt murine thymoma viral oncogene/protein kinase B [AK

38 Because the virus containing the v-akt oncogene causes T-cell lymphoma in mice and Akt is

39 t agar; however, cells overexpressing either v-akt or Akt1 became highly invasive when grown on the E

40 cells, expression of activated forms of Akt (v-Akt or myristoylated Akt) results in enhanced survival

41 homologue of the transforming viral oncogene v-Akt, plays a central role in the regulation of cell su

42 Overexpression of Akt or oncogenic v-akt protects 32D cells from apoptosis induced by IL-3

43 Sepsis inhibited the V-Akt thymoma viral oncogene homolog 1 and complex 1 of

44 tein-coupled receptors (GPCRs) activate PI3K/v-AKT thymoma viral oncoprotein (AKT) to regulate many c

45 The oncogene v-akt was isolated from a retrovirus that induced murine

46 In contrast, cells coexpressing v-Akt with v-Abl Delta858-1080 demonstrated reduced late