ライフサイエンスコーパス: vacuole

1 nactive pool of Phe, likely localized in the vacuole.

2 ctor during infection by relocalizing to the vacuole.

3 ributes to sequestering excess of Phe in the vacuole.

4 f ubiquitylation to generate its replicative vacuole.

5 lls are self-digested within the lysosome or vacuole.

6 endoplasmic reticulum (ER)-like replicative vacuole.

7 mpartment referred to as the parasitophorous vacuole.

8 he accumulation of PI(3)P on the short-lived vacuole.

9 ases such as prApe1 are transported into the vacuole.

10 at direct the formation of a parasitophorous vacuole.

11 nocytogenes escaped the original containment vacuole.

12 ed in the vesicles and delivered to the main vacuole.

13 osol, plastid, mitochondrion, peroxisome and vacuole.

14 genes, such as PH1 and PH5, that acidify the vacuole.

15 ost cells known as the Salmonella-containing vacuole.

16 d by the ESCRT machinery and degraded in the vacuole.

17 the plasma membrane-localized CgFtr1 to the vacuole.

18 TPase to promote biogenesis of the bacterial vacuole.

19 nitiate autophagosome formation at the yeast vacuole.

20 autophagosome completion and fusion with the vacuole.

21 regulate autophagy-specific fusion with the vacuole.

22 ols the constriction and luminal size of the vacuole.

23 s indicating an impaired Ca(2+) release from vacuole.

24 n within the membrane of the parasitophorous vacuole.

25 ort of bacterial cell wall lipids outside of vacuole.

26 ntracellular pathogen that damages the entry vacuole.

27 e of this pathway, into the cytosol from the vacuole.

28 Ccc1, which facilitates iron entry into the vacuole.

29 ne whether it is recycled or degraded in the vacuole.

30 can redirect the LD to the ER lumen and then vacuoles.

31 nae is contained in the apoplast rather than vacuoles.

32 reas SbSUT4 may function to release Suc from vacuoles.

33 ne, on cytosolic membrane structures, and in vacuoles.

34 degradation pathway routed via lysosomes or vacuoles.

35 Nod2, which colocalized with the parasites' vacuoles.

36 Ps were up-taken by HCECs inside cytoplasmic vacuoles.

37 eted podocytes developed massive cytoplasmic vacuoles.

38 d in the cytoplasm but accumulate inside the vacuoles.

39 ellated, and leave the Legionella-containing vacuoles.

40 and caused the appearance of large lysosomal vacuoles.

41 w within host cells in Legionella-containing vacuoles.

42 foci and failed to resolve protrusions into vacuoles.

43 eter) Munc13-4(+)/Rab7(+)/Rab11(+) endosomal vacuoles.

44 annels in Arabidopsis (Arabidopsis thaliana) vacuoles.

45 cilitated the recovery of enlarged lysosomes/vacuoles.

46 ical autophagic process that targets damaged vacuoles.

47 nal peptide transports the ER-luminal LDs to vacuoles.

48 ansport and targeting of proteins to storage vacuoles.

49 ere up-taken by the HCECs inside cytoplasmic vacuoles.

50 can be transported into and stored in plant vacuoles.

51 bin binding domain in PfHDP resulted in food vacuole abnormalities similar to that seen with a cystei

52 ts in S. cerevisiae, including impairment of vacuole acidification.

53 upernatants but not into the parasitophorous vacuole after invasion.

54 sport together with secondary storage in the vacuole allow the cell to accumulate basic amino acids t

55 way and co-migrates robustly with autophagic vacuoles along axons.

56 n of mature endosomes with the lysosome-like vacuole also requires Rab7/Ypt7.

57 onnects parasites within the parasitophorous vacuole and allows vesicles to be exchanged between para

58 ect in the fusion of autophagosomes with the vacuole and decreased autophagy activity.

59 GFP-tagged mitochondrial proteins inside the vacuole and decreased free GFP, consistent with decrease

60 y exit (egress) by sequential rupture of the vacuole and erythrocyte membranes.

61 for the formation of the Coxiella-containing vacuole and establishment of infection in Drosophila Alt

62 el that can mediate Mal(2-) release from the vacuole and is required for stomatal closure in response

63 mily members Ltc1 and Ltc3/4 function at the vacuole and plasma membrane, respectively, to create mem

64 eading to Lys63-linked ubiquitination of the vacuole and restriction of parasite early replication wi

65 different processes: protein sorting to the vacuole and sporulation.

66 termined by the relative growth rates of the vacuole and the cell, thus representing a cellular versi

67 induced formation of cytoplasmic autophagic vacuoles and activation of proteases (trypsin, chymotryp

68 ing in downstream accumulation of autophagic vacuoles and autolysosomes.

69 were associated with a loss of Mn content in vacuoles and chloroplasts.

70 a chaffeensis resides in early endosome-like vacuoles and circumvents lysosomal fusion through an unk

71 c3Delta cells, ZnMP accumulates primarily in vacuoles and does not sequentially accumulate in the cyt

72 PE cell that contains an increased number of vacuoles and enlarged (fused) vesicles that show increas

73 brane protein that controls iron export from vacuoles and inhibits Salmonella growth in macrophages.

74 which showed higher proton intensity in the vacuoles and lower intensity in cytoplasm-free spaces co

75 that promote rupture of pathogen-containing vacuoles and microbial degradation.

76 Capsids, carboxysomes, exosomes, vacuoles and other nanoshells easily self-assemble from

77 mal glycogen storage, presence of autophagic vacuoles and secondary mitochondrial abnormalities.

78 soporphyrin IX (ZnMP) first accumulates into vacuoles and then subsequently, within the cytoplasm in

79 osin system abolishes the effect of auxin on vacuoles and thus disrupts its negative influence on cel

80 ophagic pathway, leading to the formation of vacuoles and uniquely structured mitophagosomes.

81 s a consequence of its entry into autophagic vacuoles and was blocked by lysosomal cathepsin B and L

82 After arrival in the bud, Myo2 releases the vacuole, and Vac17 is degraded.

83 nfected erythrocytes but not parasitophorous vacuoles, and independently interfering with merozoite d

84 ents, progressive accumulation of autophagic vacuoles, and lysosomal dysfunction.

85 The actin cytoskeleton shows proximity to vacuoles, and the phytohormone auxin not only controls t

86 These pigments accumulate in vacuoles, and their color is influenced by chemical deco

87 and very little is known about how spacious vacuoles are formed and maintained.

88 Some of the vesicles and vacuoles are interconnected to form large networks.

89 These ER-like vacuoles are ultimately fused with the ER, where the pat

90 Using the yeast vacuole as a model, we tested whether mutants defective

91 vacuoles, or peroxisomes sequestered within vacuoles as a result of pexophagy.

92 Moreover, we reveal that autophagic vacuole-associated BACE1 is accumulated in the distal ax

93 its cognate SNAREs and HOPS, yet the overall vacuole association of Vam7-6A was similar to wild type.

94 tributed to the observed wild type levels of vacuole association, whereas protein-protein interaction

95 8Delta/vac17Delta cells continued generating vacuole at roughly constant rates even when they had sig

96 sed lipid droplets (LDs), reduced autophagic vacuoles (AVs) and less LC3B puncta.

97 hallenges of transporting nascent autophagic vacuoles (AVs) from distal axons toward the soma, where

98 inheritance, vac8Delta and vac17Delta, tune vacuole biogenesis in response to perturbations in vacuo

99 results suggest there is no feedback between vacuole biogenesis rates and vacuole or cell size.

100 aging micron-scale membrane domains of yeast vacuoles both in vivo and cell free, we demonstrate that

101 Anthocyanins are usually soluble in the vacuole, but in some plants, they accumulate as discrete

102 marker GFP-ATG8e, indicating delivery to the vacuole by autophagy.

103 isrupts the fusogenicity of the MVB, not the vacuole, by targeting pH-sensitive machinery downstream

104 ia trachomatis replicate in a membrane-bound vacuole called inclusion, which serves as a signaling in

105 previously thought to remain sealed within a vacuole can be recognized by cytosolic innate immune sen

106 e, two membrane transporter genes, including vacuole cation/proton exchanger and inositol transporter

107 lted in the development of large cytoplasmic vacuoles caused by arrested endocytic traffic progressio

108 ost cells within a large Coxiella-containing vacuole (CCV) whose biogenesis relies on the Dot/Icm-dep

109 ellular niche termed the Coxiella-containing vacuole (CCV).

110 ntain microcolonies of Salmonella-containing vacuoles close to the microtubule organizing center of i

111 omponents to nascent Cryptococcus-containing vacuoles (CnCVs) regulates the intracellular trafficking

112 ates even when they had significantly larger vacuoles compared to wild-type.

113 , which are known to destroy the membrane of vacuoles containing bacteria, protists, or fungi.

114 displayed an increased number of autophagic vacuoles containing degenerated and swollen mitochondria

115 We have shown that vacuoles containing engulfed material undergo mTORC1-dep

116 eries that have defined interactions between vacuoles containing L. pneumophila and the host ER.

117 osomes and Vps33 in early and late endosomes/vacuoles contributes to the wide domain of PepA(Pep12) a

118 by regulating Na(+) and Ca(2+) fluxes in the vacuole, cooperating with the vacuolar cation channel Sl

119 microalgae, with high enrichments present in vacuoles, cytoplasm and chloroplasts.

120 t replicates in an acidified parasitophorous vacuole derived from host lysosomes.

121 Ehrlichial vacuoles did not colocalize with the lysosomal marker LA

122 ns (swollen mitochondria, intramitochondrial vacuoles, disordered mitochondrial capsule).

123 The transverse tubules and vacuoles displayed distinct Ca(2+)-handling properties.

124 ges of flower development and sequestered in vacuoles during the lifespan of the flowers.

125 -parasite interaction at the parasitophorous vacuole employed by Toxoplasma and host, leading to the

126 etes numerous proteins to modify the forming vacuole, enable nutrient uptake, and set up mechanisms o

127 addition to its role in PlcB processing and vacuole escape, the metalloprotease Mpl is required for

128 eltaplcB strain displayed a strong defect in vacuole escape.

129 ity, and PlcB, a phospholipase that mediates vacuole escape.

130 addition to the expected but mild defect in vacuole escape.

131 The L. pneumophila-containing vacuole evades fusion with lysosomes and interacts intim

132 large PI(3)P-positive membranes to CCVs for vacuole expansion.

133 target membrane proteins to the lysosome or vacuole for degradation, can also function as recycling

134 associated with ILVs and is delivered to the vacuole for degradation.

135 ivers endoplasmic reticulum fragments to the vacuole for degradation.

136 ssary or damaged cytoplasmic material to the vacuole for its degradation and recycling in order to ma

137 Ca(2+) responses, 4) cytoplasmic autophagic vacuole formation, and 5) protease activation.

138 degradation of Vac17 and the release of the vacuole from Myo2.

139 efficient evasion of the Brucella-containing vacuole from the phagocytic route in professional phagoc

140 The resolution of membrane protrusions into vacuoles from which the pathogen escapes results in bact

141 In vitro reconstitution of homotypic yeast vacuole fusion from purified components enables detailed

142 BR to an alanine (Vam7-6A) led to attenuated vacuole fusion.

143 making unclear how these organisms regulate vacuole fusion.

144 Vacuole generation involved the homotypic fusion of Munc

145 a, the endoplasmic reticulum, lysosomes, and vacuoles have the capacity for Ca(2+) transport across t

146 g ER-derived membranes for biogenesis of the vacuole in which L. pneumophila replicates, these studie

147 C) were identified as components of M. avium vacuoles in macrophages.

148 l Wnt3a ligand induced autophagy markers and vacuoles in murine PanIN cells.

149 LDH, in parallel to the presence of numerous vacuoles in the cytoplasm, a decrease in collagen I prod

150 system to exist inside Salmonella-containing vacuoles in the macrophage, as well as to persist as asy

151 vealed age-dependent increases of autophagic vacuoles in the SNpc of LRRK(-/-) mice before the onset

152 which subsequently fuses with a lysosome or vacuole (in mammals, or yeast and plants, respectively),

153 defect in the resolution of protrusions into vacuoles, in addition to the expected but mild defect in

154 his study, we report that enlarged lysosomes/vacuoles induced by either vacuolin-1 or P2X4 activation

155 odel, we tested whether mutants defective in vacuole inheritance, vac8Delta and vac17Delta, tune vacu

156 ib caused virions to be present inside large vacuoles inside the cells.

157 The presence of vesicles and vacuoles inside the PMCs that have openings through the

158 he regulation of BR signaling by maintaining vacuole integrity required to balance subcellular BAK1 p

159 he conversion of the plasma membrane-derived vacuole into an endoplasmic reticulum (ER)-like replicat

160 The parasitophorous vacuole is a unique replicative niche for apicomplexan p

161 Because the yeast vacuole is an analogue of the mammalian lysosome, our fi

162 Derived from host plasma membrane, the vacuole is rendered nonfusogenic with the host endolysos

163 K(+) and Mal(2-) Efflux of Mal(2-) from the vacuole is required for stomatal closure; however, it is

164 he delivery of GBP2 to Legionella-containing vacuoles is dependent on the bacterial Dot/Icm secretion

165 way for degradation of macromolecules in the vacuole, is activated by these stress agents in a manner

166 defined geographical location at the nucleus-vacuole junction contact site.

167 me-mitochondrion contacts and to the nuclear-vacuole junctions, indicating that Vps13 may function at

168 ay (EDX) analyses showed a higher cytoplasm: vacuole K(+) ratio which is likely to contribute to the

169 pathways and forming a Legionella-containing vacuole (LCV) in which the bacteria replicate.

170 phages and amoeba, the Legionella-containing vacuole (LCV) membrane is derived from the ER.

171 o large numbers in the Legionella-containing vacuole (LCV), as evident at 12 h.

172 e ER structures into Liberibacter containing vacuoles (LCVs), in which bacterial cells seem to propag

173 murium bacteria damage their internalization vacuole, leading to escape from the Salmonella-containin

174 itment of TRIM21 to GBP1-positive Toxoplasma vacuoles, leading to Lys63-linked ubiquitination of the

175 and associated with aberrant accumulation of vacuole-like structures at the apical inner segment and

176 t OsHMA4 functions to sequester Cu into root vacuoles, limiting Cu accumulation in the grain.

177 o enhance aphid reproduction on host plants, vacuole localization disappears when aphids are removed,

178 each with distinct apical diameter, central vacuole location, and distribution of cell wall componen

179 gen metabolism enzymes are secreted into the vacuole lumen through type 3 secretion.

180 o sorting and direct cargo delivery into the vacuole lumen.

181 coli is sufficient to promote the efficient vacuole lysis and escape of the modified bacteria into t

182 ation across bacterial species, we show that vacuole lysis is not a common feature of T3SA, as an eff

183 d for efficient bacterial invasion and rapid vacuole lysis within select host cell types, indicating

184 uole-specific adapter Vac17 to attach to the vacuole/lysosome and initiate transport.

185 AD substrates and are targeted mainly to the vacuole/lysosome for degradation, leading to predictions

186 s autophagy, phagosome maturation, and lytic vacuole/lysosome, and contained the vacuolar H(+)-ATPase

187 At the vacuole/lysosome, they are integrated by the homotypic f

188 gulated by Pho85/CDK5 via signaling from the vacuole/lysosome, which is distinct temporally and spati

189 utophagy-dependent delivery of Htt103QP into vacuoles (lysosomes).

190 identify PIKfyve as a critical regulator of vacuole maturation and nutrient recovery during engulfme

191 Evidence is emerging that the vacuole may be key to removal of unwanted plant cells, a

192 owever, the evolution of the calcium-storing vacuole may provide plants with additional possibilities

193 acute water stress damage shows parallels to vacuole-mediated cell death where the generation of sing

194 fore our data indicate that Dsk2 facilitates vacuole-mediated clearance of misfolded proteins by prom

195 recruitment of LC3 onto the parasitophorous vacuole membrane (PVM) and increased the colocalization

196 ar reservoirs and attack the parasitophorous vacuole membrane (PVM) as orchestrated, supramolecular c

197 We show that the parasitophorous vacuole membrane (PVM) is permeabilized 10-30 min before

198 eds to attach to the internal surface of the vacuole membrane before releasing efferent molecules, va

199 ution from ER exit sites onto liquid-ordered vacuole membrane domains, initiating micro-lipophagy.

200 4(-) parasites, which lack a parasitophorous vacuole membrane protein and arrest during liver-stage d

201 onents of the sorting machinery required for vacuole membrane protein degradation.

202 These tests revealed that ubiquitinated vacuole membrane proteins recruit ESCRTs to the vacuole

203 embrane before releasing efferent molecules, vacuole membrane proteins were purified and binding to t

204 n function at both the late endosome and the vacuole membrane to mediate cargo sorting and intra-lumi

205 ion of the gamete-containing parasitophorous vacuole membrane, and thus for parasite transmission to

206 ions as a nonselective cation channel on the vacuole membrane, whereas mammalian TPC channels have be

207 based gene editing, identified the digestive vacuole membrane-spanning transporter PfMDR1 (P. falcipa

208 ing of spore dormancy, Ctr6 localizes to the vacuole membranes that are enriched in the spore body re

209 p1 and Vps13 work as functional effectors of vacuole-mitochondria contact sites, while tethering is m

210 itochondria and promoting its association to vacuole-mitochondria contacts.

211 Tethered and functionally active vacuole-mitochondria interfaces then compensate for the

212 g organelles in the phloem, such as plastid, vacuole, mitochondrion, or endoplasmic reticulum, intera

213 S1 (LAZ1) and LAZ1 HOMOLOG1 (LAZ1H1), causes vacuole morphology defects, growth inhibition, and const

214 Since unrelated vacuole mutants exhibited normal BR responses, our findi

215 parasites that sequester themselves within a vacuole, new rules governing antigen presentation are co

216 ese findings we propose that parasitophorous vacuoles not only offer protection but also provide a mi

217 eplicate exclusively within the cytoplasm or vacuole of a eukaryotic cell.

218 nto the acidocalcisome- and lysosome-related vacuoles of yeast, where it can be released again.

219 eedback between vacuole biogenesis rates and vacuole or cell size.

220 followed by further storage or metabolism in vacuoles or cell walls.

221 ry of GBP1 and GBP2 to Legionella-containing vacuoles or YCVs is substantially diminished in Galectin

222 of cells with poor differentiation and large vacuoles, or in small and ill-defined glands.

223 firmed that the enlarged structures were not vacuoles, or peroxisomes sequestered within vacuoles as

224 ellular infiltration, angiogenesis, or fatty vacuoles; or grade 3, severe tendinopathy, with loss of

225 l/lysosomal fusions with parasite-containing vacuoles (parasitophorous vacuoles [PV]).

226 tified as a novel class of malaria digestive vacuole plasmepsin inhibitors by using NMR-based fragmen

227 notubular network within the parasitophorous vacuole play a major role in determining antigenicity of

228 Deletion of ATG genes or inhibition of vacuole protease activity compromises Rph1 turnover.

229 y are integrated by the homotypic fusion and vacuole protein sorting (HOPS) complex.

230 manner dependent on the homotypic fusion and vacuole protein sorting (HOPS) tethering complex.

231 GTPase 8) and its effector homotypic fusion/vacuole protein sorting complex (HOPS) to (phago)lysosom

232 tethering complex HOPS (homotypic fusion and vacuole protein sorting complex), whereas the C-terminal

233 exameric vacuolar HOPS (homotypic fusion and vacuole protein sorting) complex in the yeast Saccharomy

234 For intracellular pathogens, residence in a vacuole provides a shelter against cytosolic host defens

235 tion of significant amounts of Ca(2+) within vacuoles provides an effective mechanism to reduce the t

236 f the metal uptake transporter NRAMP1 to the vacuole, providing a rationale for the reversion of nram

237 replication niche termed the parasitophorous vacuole (PV) by directing fusion with autophagosomes and

238 sma gondii develops within a parasitophorous vacuole (PV) in mammalian cells, where it scavenges chol

239 ltiplies in a membrane-bound parasitophorous vacuole (PV) that interacts with mammalian host organell

240 ates inside a membrane-bound parasitophorous vacuole (PV), which shields this intracellular parasite

241 anous compartment termed the parasitophorous vacuole (PV).

242 ucing the destruction of the parasitophorous vacuole (PV).

243 arasite-containing vacuoles (parasitophorous vacuoles [PV]).

244 asive bacteria establish pathogen-containing vacuoles (PVs) as intracellular niches for microbial gro

245 rforin-2(-/-)macrophages,Listeria-containing vacuoles quickly (</= 15 min) acidify, and that this was

246 a replication-permissive Brucella-containing vacuole (rBCV) derived from the host ER, a process that

247 ling and vacuolar targeting, but the role of vacuole-related proteins in BR receptor dynamics and BR

248 ficking of the AtPep1-PEPR1 complexes to the vacuole required neither the trans-Golgi network/early e

249 The yeast vacuole requires four SNAREs to trigger membrane fusion

250 Mutations in both digestive vacuole-resident transporters are thought to differentia

251 e (AO) were localized to the plasmalemma and vacuole, respectively.

252 based 3D nanometer-resolution imaging of the vacuoles revealed that auxin controls the constriction a

253 BM) pathogenesis is unknown; however, rimmed vacuoles (RVs) are a constant feature.

254 ature, we termed these structures "renitence vacuoles" (RVs).

255 In vac8Delta/vac17Delta, vacuole scaling increases with the replicative age of th

256 ing to escape from the Salmonella-containing vacuole (SCV) and extensive proliferation in the cytosol

257 eted into the lumen of Salmonella-containing vacuole (SCV), after which it is packaged into vesicle c

258 tic compartments between early endosomes and vacuoles, shares features of Vam3p and Pep12p, and is ca

259 (SlTPC1), key genes for Ca(2+) fluxes to the vacuole, showed abnormal expression in Slcbl10 plants in

260 Modified oleosin with an added vacuole signal peptide transports the ER-luminal LDs to

261 M is required for the regulation of lysosome/vacuole size by TRPML1, suggesting that TRPML1 may promo

262 We find that PIKfyve regulates vacuole size in part through its downstream effector, th

263 Moreover, the effects of TRPML1 on lysosome/vacuole size regulation were eliminated by Ca(2+) chelat

264 e biogenesis in response to perturbations in vacuole size.

265 erevisiae, the myosin V motor Myo2 binds the vacuole-specific adapter Vac17 to attach to the vacuole/

266 nges in osmolyte concentration of guard cell vacuoles, specifically of K(+) and Mal(2-) Efflux of Mal

267 lus electron micrographs indicating enlarged vacuoles suggested vacuolar storage of NO3(-) Triacylgly

268 PIKfyve promotes recovery of nutrients from vacuoles, suggesting a potential link between PIKfyve ac

269 uole membrane proteins recruit ESCRTs to the vacuole surface, where they mediate cargo sorting and di

270 The cytoplasm-to-vacuole targeting pathway is a variant of selective auto

271 4 in cargo engulfment, Atg26 in cytoplasm-to-vacuole targeting, and Ssd1, Did4, and others in selecti

272 3-6] translocates into the Ct membrane-bound vacuole, termed inclusion, and remains associated with m

273 mechanism by which the Chlamydia-containing vacuole, termed the inclusion, establishes direct contac

274 h results in the formation of the ER-derived vacuole that supports L. pneumophila replication.

275 Engulfed macromolecules are contained within vacuoles that are targeted for lysosome fusion to initia

276 in fibroblasts exhibited the accumulation of vacuoles that is characteristic of PI(3,5)P2 deficiency.

277 In the acidic macrophage vacuole, the kinase SsrA phosphorylates SsrB, and SsrB~P

278 ing the acidification of Listeria-containing vacuoles, thereby depriving the pathogen of favorable in

279 eveal that host glycogen stores shift to the vacuole through two pathways: bulk uptake from the cytop

280 brane of the host-derived R. equi containing vacuole, thus providing an opportunity for VapA to inter

281 ration of heavy metal(loid)s inside the cell vacuole to alleviate toxicity.

282 cytes and replicate within a parasitophorous vacuole to form daughter cells that eventually exit (egr

283 ce, Na(+) and Cl(-) are sequestered into the vacuole to help maintain cytosolic ion homeostasis and a

284 rk that signals a successful delivery of the vacuole to the bud.

285 in the mobilization of stored heme from the vacuole to the cytosol.

286 fection, autophagosomes fuse with ehrlichial vacuoles to form an amphisome indicated by the presence

287 Moreover, the virus hijacks the autophagic vacuoles to mature in an acidic environment and release

288 ow in cultured Perforin-2(-/-)cells that the vacuole-to-cytosol transitioning of L. monocytogenesis g

289 ll signalling, cell polarity and morphology, vacuole trafficking, transfer RNA (tRNA) modification an

290 that YDR089W encodes a novel subunit of the vacuole transporter chaperone (VTC) complex that produce

291 sition of LC3 on L. monocytogenes-containing vacuoles via noncanonical autophagy had no apparent role

292 minantly expressed in the tonoplast of small vacuoles, we generated overexpressing (OX) lines using a

293 urally, swollen mitochondria and cytoplasmic vacuoles were also noted in remaining melanocytes and so

294 luorescence microscopy imaging revealed that vacuoles were exocytic and mediated secretion of beta-he

295 orter SLC35D2 to import UDP-glucose into the vacuole, where it serves as substrate for de novo glycog

296 Saccharomyces cerevisiae stores iron in the vacuole, which is a major resistance mechanism against i

297 that TPKb can alter the K(+) status of small vacuoles, which is important for general cellular K(+) h

298 membrane ruffling, and porphyrin-containing vacuoles with endoplasmic reticulum distortion.

299 formation of dynamic droplet substructures (vacuoles) with tunable lifetimes.

300 the delivery of GBP2 to Yersinia-containing vacuoles (YCVs) requires hypersecretion of Yersinia tran