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1 -/-) fibroblasts was effective in preventing vacuolization.
2 cells and induces cell death by catastrophic vacuolization.
3 matin, nuclear segmentation, and cytoplasmic vacuolization.
4 d age-dependent neurodegeneration visible as vacuolization.
5 cell cycle arrest, and increased cytoplasmic vacuolization.
6  months, which is accompanied by gliosis and vacuolization.
7 ervation preceded mitochondrial swelling and vacuolization.
8 ns rich in neuronal cell bodies also display vacuolization.
9 ization, and blebbing as well as cytoplasmic vacuolization.
10  correlated with notochord extension through vacuolization.
11 rstitial inflammation, fibrosis, and tubular vacuolization.
12  was a higher frequency of isometric tubular vacuolization (71 % vs. 31%) and more widespread involve
13 ndings in MDS do not include myeloid lineage vacuolization, abnormal nuclear lobulation of both eryth
14 ng cytotoxin gene vacA, resulting in loss of vacuolization activity.
15 zation and rejection and 14 biopsies showing vacuolization alone.
16 e are degenerative features characterized by vacuolization and accumulation of stressor and amyloid-r
17 ia/ischemia but also may induce brain tissue vacuolization and alter glucose metabolism.
18 icity (gck, gsr and nqo1) and caused hepatic vacuolization and apoptosis as well as increase of the l
19 CH is characterized by widespread hepatocyte vacuolization and apoptosis, which, in contrast to more
20 , ventriculomegaly, cytomegaly and extensive vacuolization and astrocytosis of white matter.
21 uctural abnormalities in astrocytes, such as vacuolization and astrogliosis.
22 reas K8/K18 pancreata displayed age-enhanced vacuolization and atrophy of the exocrine pancreas and e
23 like membrane structures in association with vacuolization and cell death.
24  its synthesis in skeletal myofibers induces vacuolization and contraction impairment.
25 used spontaneous and progressive acinar cell vacuolization and death, interstitial fibrosis, inflamma
26                  Cellular defects, including vacuolization and disrupted mitochondria, were observed
27 lls arrest in G1/G0 phase and suffer massive vacuolization and eventual cell death by autophagy.
28 ycle arrest that was associated with massive vacuolization and expansion of the ER.
29 34-deficient podocytes exhibited substantial vacuolization and foot process effacement.
30                                              Vacuolization and gliosis were evident before clinical o
31 e hepatocytes, which resulted in cytoplasmic vacuolization and increased cell damage closely resembli
32 pearing, squamous epithelium with occasional vacuolization and keratinization.
33 rovesicular tubular epithelial cytoplasmatic vacuolization and luminal dilatation with flattening of
34  renal tubular cell desquamation, with toxic vacuolization and mitochondrial swelling as hallmarks of
35 ated cells revealed cytoplasmic changes with vacuolization and mitochondrial swelling, nuclear conden
36 ak expression demonstrated massive cytosolic vacuolization and multifocal nuclear chromatin condensat
37 and ultrastructural analyses revealed severe vacuolization and myelination defects in all white matte
38 reas MK-801 produced characteristic neuronal vacuolization and necrosis in the posterior cingulate/re
39 5)NMDA receptor antagonists produce neuronal vacuolization and necrosis in the rat posterior cingulat
40 g astrocytes and neurons, showed cytoplasmic vacuolization and other degenerative changes.
41 cludes Z-disc streaming, excess myofibrillar vacuolization and plaque-like myofibrillar aggregation.
42                  There was striking podocyte vacuolization and proteinaceous casts, with marked glome
43 enal allograft biopsies showing both tubular vacuolization and rejection and 14 biopsies showing vacu
44 eatment with doxorubicin induced cytoplasmic vacuolization and severe damages in myofilaments and nuc
45  electron microscopy, extensive sarcoplasmic vacuolization and severe disruption of mitochondrial fin
46 y showed significantly increased cytoplasmic vacuolization and significantly decreased mitotic activi
47             We propose that these cells, via vacuolization and stiffening, gave rise to the chordate
48 All these steps are required for cytoplasmic vacuolization and subsequent cytolysis to occur.
49 virus induced marked cytopathologic changes (vacuolization and syncytium formation) in infected micro
50 y dying vacuolated cells promote sheath cell vacuolization and trans-differentiation.
51         Remarkably, MPN372 elicits extensive vacuolization and ultimate cell death of mammalian cells
52 a distinct morphology exhibiting cytoplasmic vacuolization and, finally, cytolysis.
53 nimals included proximal tubule collapse and vacuolization and, less frequently, interstitial edema a
54 oint pertinent adverse outcomes (i.e., liver vacuolization) and groups of chemicals that preselected
55 vascular cell interactions, endothelial cell vacuolization, and an overall failure of vascular organi
56  Moreover, MLKL phosphorylation, cytoplasmic vacuolization, and cytolysis were observed in eosinophil
57 iopsies showed epidermal atrophy, basal cell vacuolization, and diffuse dermal sclerosis in the absen
58  as shown by nuclear morphology, cytoplasmic vacuolization, and host cell DNA fragmentation.
59      Podocyte pathology included effacement, vacuolization, and hypertrophy with crescent formation.
60 plasm of affected cells displayed subnuclear vacuolization, and in some cases, nuclei of affected cel
61 imple cold stored tissue displayed increased vacuolization, and machine perfused tissue showed region
62 n microscopy showed cytoplasmic swelling and vacuolization, and marked decrease or absence of dense-c
63 ltrate, hypercellular appearance, pronounced vacuolization, and mucoid degeneration, appearing as Wal
64 cell morphological changes such as swelling, vacuolization, and nuclear fragmentation following treat
65 erulein reduced hyperamylasemia, acinar cell vacuolization, and pancreatic inflammation but did not a
66 , and replicate within, the RGC resulting in vacuolization, and ultimately lysis, of the RGC.
67    On light microscopy cytoplasmic swelling, vacuolization, apoptosis, and abnormal immunostaining fo
68 ative stress, and mitochondrial swelling and vacuolization are among the earliest pathologic features
69                   Mitochondrial swelling and vacuolization are early signs of incipient motor neuron
70 degeneration with fiber size variability and vacuolization, as well as reduced motor performance, fea
71 injury stimulus resulted in focal epithelial vacuolization at birth, but otherwise normal tubule hist
72 GlcNAc-Asn was detected along with lysosomal vacuolization, axonal swelling in the gracile nucleus an
73 s characterized in part by early cytoplasmic vacuolization before nuclear changes occur.
74 to show variable degrees of degeneration and vacuolization by postnatal day 21.
75 gy studies revealed an extensive cytoplasmic vacuolization coherently with a paraptosis-like cell dea
76 ncluding cell membrane blebbing, cytoplasmic vacuolization, condensation of nuclear chromatin, and nu
77 vere proximal tubule injury characterized by vacuolization, decreased uncoupling of protein-2 express
78 ressive loss of electroretinograph response, vacuolization, degeneration of the RPE, thickening of Br
79 tic edge IOLs included iris changes, such as vacuolization, disruption and loss of the pigmented epit
80 illumination defects, iris changes including vacuolization/disruption/loss of the pigmented layer, ir
81 ypical features of PCD including cytoplasmic vacuolization, DNA condensation, and apoptotic body form
82  lacking c-Jun displayed massive cytoplasmic vacuolization due to ER distension.
83 ulted in significantly attenuated pancreatic vacuolization, edema, necrosis, inflammation, and enzyme
84   Podoptosis was associated with cytoplasmic vacuolization, endoplasmic reticulum stress, and dysregu
85  L-e-sphingosine, caused massive perinuclear vacuolization, Golgi fragmentation, and cell rounding.
86 showing both rejection and isometric tubular vacuolization has not been well defined in the literatur
87 xamination showed chromatin condensation and vacuolization in a fraction of cells infected with d120
88 ddition, the C-terminal region alone induces vacuolization in a manner similar to full-length toxin.
89 ophages (which are characterized by abundant vacuolization in Arsg KO mice) and oligodendrocytes.
90 nsation of nuclear chromatin and perinuclear vacuolization in focal areas.
91 protein aggregates and for reducing cellular vacuolization in HCT116 colon cancer cells and DU145 pro
92                          We observed similar vacuolization in outer segments of transgenic mice expre
93 cularly in neurons, elevated plasma gastrin, vacuolization in parietal cells, and retinal degeneratio
94  frequency and severity of isometric tubular vacuolization in renal allograft biopsy specimens obtain
95                                        Focal vacuolization in some of the seminiferous tubules was ob
96 st evidence of myocardial injury was myocyte vacuolization in the absence of microvascular thrombosis
97 used loss of motility, cell enlargement, and vacuolization in the algal cells.
98 e in Sp4 hypomorphic mice resulted in subtle vacuolization in the hippocampus as well as deficits in
99 erfusion, the core ischemic region exhibited vacuolization in the neuropil by 36 h after ischemia, an
100 oxygenation exposure for 8 weeks resulted in vacuolization in the perikarya and dendrites and markedl
101 hology in HeLa cells by inducing cytoplasmic vacuolization in the presence of ammonium chloride.
102                      The pathogenesis of the vacuolization in this clinical setting is not clear, but
103 bit behavioral abnormalities and progressive vacuolization in various brain regions.
104                            Isometric tubular vacuolization is a common finding in renal transplant bi
105 rown adipose tissue of Ppt1-KO mice had less vacuolization (lipid droplets) compared to wild-type ani
106 by 42%, and there was extensive Sertoli cell vacuolization, loss of germ cells, reduced sperm counts,
107 d no change in the size or extent of tubular vacuolization (mean score 2.88+/-0.19 vs. 2.83+/-0.21).
108  neuromuscular denervation and mitochondrial vacuolization, MNs were completely rescued from mutant S
109  characterized by neutrophilic infiltration, vacuolization of acinar cells, and foci of necrosis.
110 dema, pancreatic trypsinogen activation, and vacuolization of acinar cells.
111  seizures cause an immediate, but transient, vacuolization of astrocytes, followed over several days
112                     Cellular destruction and vacuolization of basal epithelial cells associated with
113 inguish these entities including cytoplasmic vacuolization of both erythroid and myeloid precursors,
114 rate rescued lipid accumulation and apparent vacuolization of brown adipose tissue in the HD mice.
115                          Despite significant vacuolization of endosomal compartments similar to SPPL2
116                                              Vacuolization of fibroblasts was rescued by transfection
117 livers 24 hr after transplantation, moderate vacuolization of hepatocytes by histology with the immun
118 and, less frequently, interstitial edema and vacuolization of interstitial cells.
119 idge, a loss of OHCs from cochlear apex, and vacuolization of OHCs.
120 y specimens of these allografts is isometric vacuolization of proximal tubular epithelium.
121 trix, rounding, a mottled cell membrane, and vacuolization of the cytoplasm, all of which are indicat
122 used an increase in cell size, and triggered vacuolization of the cytoplasm.
123 croscopy of the retinas revealed progressive vacuolization of the photoreceptor outer segments.
124 o a thinning of the nonpigmented epithelium, vacuolization of the pigmented epithelium, loss of capil
125                                              Vacuolization of the T9-C2 cell's mitochondria and endop
126 gnal on acid hydrolases, exhibited extensive vacuolization of their exocrine gland cells, while the l
127                         Nonspecific changes (vacuolization of tubular cells, loss of brush border, an
128 re degeneration of the BLB, there was severe vacuolization or frank apparent necrosis of VECs and los
129  appears to play some role in the process of vacuolization or vacuole fusion leading to intercellular
130 res accompanying loss of cell viability were vacuolization, other changes in cell morphology, and inc
131 hibit numerous defects including aneuploidy, vacuolization, protruding spikes, and precocious fusion
132  there was a significant association between vacuolization score and blood tacrolimus level on the da
133                                      Myocyte vacuolization seems to be an early feature of delayed xe
134 ei associated with gliosis and intramyelinic vacuolization similar to that observed in cytotoxic edem
135 glomerular cell count with focal cytoplasmic vacuolization, suggesting increased degranulation, was a
136                                Mitochondrial vacuolization, swelling, and dissolution of cristae occu
137 membrane permeability, blebbing, cytoplasmic vacuolization, swollen mitochondria, low adenosine triph
138 tudies indicated that 13 induces cytoplasmic vacuolization that is lysosomal in nature.
139 gy is characterized by extensive cytoplasmic vacuolization that is rarely observed in degenerating co
140  vesicles, and induces extensive cytoplasmic vacuolization that is reminiscent of autophagy.
141 cumulation and massive endoplasmic reticulum vacuolization that precede a nonapoptotic (paraptotic) c
142 ological changes including tubular swelling, vacuolization, thrombotic microangiopathy, and increased
143 tarting at approximately 20 weeks of age and vacuolization throughout the renal cortex in older mice.
144 gions of coagulative necrosis and hepatocyte vacuolization unapparent in mice carrying either infecti
145  with concurrent acute rejection and tubular vacuolization usually benefit from increased immunosuppr
146                                              Vacuolization was also seen in the brain.
147                                    Isometric vacuolization was graded on a 0 to 4 scale based on the
148 c cardiomyocytes, but almost no sarcoplasmic vacuolization was observed, and the mitochondrial struct
149 riking necrotic features such as cytoplasmic vacuolization, watery cytoplasm, and dissolution of orga
150  the presence of great number of cytoplasmic vacuolization were healed by SP2.
151 necrosis and hepatic glycogen depletion with vacuolization were more severe after infection with the
152 miniferous tubules, germ cell depletion, and vacuolization), whereas testicular structure was remarka
153 c; swelling, dendritic retraction, blebbing, vacuolization, which are all characteristics of necrosis
154       From 3 months, widespread white matter vacuolization with intramyelinic edema developed.
155 e exhibited loss of the basal infoldings and vacuolization, with accumulation of amorphous deposits b

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