ライフサイエンスコーパス: validate

1 4-tetrahydroisoquinoline, was experimentally validated.

2 ulatory elements have yet to be functionally validated.

3 theory calculations have been performed and validated.

4 l, almost none of which are yet functionally validated.

5 The model was internally and externally validated.

6 nk between TMAO and such diseases is not yet validated.

7 o characterize the highest mobility level, a validated 11-point mobility scale was collapsed into fou

8 tative framework for their further study and validate 14alpha-demethylase as the target for azoles in

9 ietary intake was assessed with the use of a validated 192-item semiquantitative food-frequency quest

10 These findings were validated 24 hours after removal of GNPs by flow cytomet

11 inverse energy cascade in an experimentally validated 3D active fluid model, describing microbial su

12 ubscales, changes in vaginal atrophy using a validated 4-point scale, and comparison of E2 levels.

13 We validated (68)Ga-DOTATATE PET as a novel marker of ather

14 ons of morphology of ultralow velocity zones validate a compositionally distinct origin for most ultr

15 Here we describe and computationally validate a framework that combines the cancer-specific l

16 In this study, we attempted to validate a MALDI-ToF mass spectrometry-based assay for t

17 (simulated) smoking for the first time, and validate a novel approach to the study of smoking, and a

18 To develop and externally validate a simplified prognostic score for ICC and to de

19 iduals, we developed and independently cross-validated a biomarker assay to predict mortality based o

20 We developed and validated a multivariate whole-blood mRNA-based predicto

21 INTERPRETATION: We developed and validated a novel clinical prediction model with good di

22 in a recent multicenter study developed and validated a novel prognostic index, Risk Estimation of T

23 Here, we constructed and validated a predictive computational model of the cardia

24 Overall, our results validated a rapid, reproducible, and low-cost platform f

25 We developed and validated a rapid, sensitive, and robust method, the pol

26 xenogeneic biomaterial (i.e. BP) and further validates a rapid, high-throughput method for immunoprot

27 nges enhancing the target electrostatics are validated against drug-target affinity data, yielding su

28 The SERS determination of MC-LR was cross validated against ELISA.

29 Our model predictions are validated against experimental (1)H NMR data, demonstrat

30 Moreover, the new SPME probes were used to validate an analytical method for determination of banne

31 e find regulated by novel MYC-binding sites, validating an additional transcriptional activation role

32 This study aims to validate and apply clinically meaningful bands to the It

33 We needed to validate and calibrate our portable acuity screening too

34 ied in rumen and plasma using targeted MS to validate and evaluate the simple combination of metaboli

35 We also validate and illustrate the application of our algorithm

36 of Biolog phenotype data and fitness data to validate and refine our KPPR1 model.

37 n bone model has been well characterized and validated and allows dissection of some of the mechanism

38 In summary, we have implemented, validated and tested the ME-EP-JRESI sequence, demonstra

39 The proposed method was validated and used to analyse a variety of baby food sam

40 This study validates and quantifies PR and CR as surrogates for lon

41 It was internally bootstrap validated, and externally validated in 1,547 patients in

42 Ncr1071, Syr6 and NsiR7 were experimentally validated, and their putative targets were computational

43 We used a validated approach involving InternationalClassification

44 ll molecules CD44 and EZH2, all of which are validated as direct and functionally relevant targets of

45 We validated association at all nine previously described s

46 untested conditions that must be empirically validated before it is certain that any lineage of ECM f

47 y of Pseudomonas aeruginosa ATCC9027 and its validated bioluminescent strains for preservative effica

48 early-phase patient trials, but the lack of validated biomarkers of disease progression presents a c

49 Furthermore, there are currently no validated biomarkers that predict which mRCC patients wi

50 infection activates BRD4 in vivo These data validate BRD4 as a major effector of RSV-induced inflamm

51 The enzyme conformational change was validated by 3D fluorescence and CD spectrum.

52 This prediction was validated by a combination of simulation experiments of

53 NS-1E cells, and the binding specificity was validated by a CRISPR/Cas9 mediated ZnT8 knock-out.

54 The consensus process was validated by an extended group (EG) of ISIC members thro

55 egation of microbiota compositions which was validated by Beta diversity analysis.

56 es are identified, and most of the genes are validated by cDNA and RNA-seq data.

57 ng surrogate signatures to train the ANN was validated by comparing blood levels among cigarette smok

58 The prepared immunosensor was validated by determining TGF-beta1 in real saliva sample

59 l surface area, approximately 4.7 times), as validated by electrochemical measurements and first-prin

60 by sequence alone and their activities were validated by enzymatic assays with the recombinant prote

61 ogical and immunocytochemical analysis, then validated by functional electrophysiological evaluation.

62 nt metastasis in TNBC (P = 0.01) was further validated by immunohistochemistry.

63 The identified genes were validated by immunohistochemistry.

64 e recruitment of the CXCR2(+) stem cells, as validated by in vitro and in-matrix migration assays.

65 The radiochemical procedure was validated by its application for the measurement of IAEA

66 terize this spatial organization, when cross-validated by other sensitive methodologies, exhibit negl

67 tory generated HONO (400 ppbv to 1 ppmv) and validated by parallel HONO collection with a standard, b

68 Thirteen transcripts were validated by qPCR to confirm cell specific expression in

69 This approach is validated by quantitative measurements of enzyme activit

70 target transcripts, predicted in silico and validated by RT-qPCR, often showed opposite expression p

71 peripheral blood BDNF levels in SCZ patients validated by several meta-analyses.

72 The method was further validated by showing that the 3D printed material was we

73 n that the loop is relocated by pressure was validated by site-directed mutagenesis and by inhibition

74 Assay was validated by spiking OTC to antibiotic free milk samples

75 The simulated extraction yield of 17.91% was validated by the experimental result (16.67+/-0.30).

76 The MISPE method was validated by UPLC-MS/MS for the determination of AOH and

77 l-energy material densities was assessed and validated by using 10-fold cross-validation to limit the

78 implanted subcutaneously in rats by using a validated cage model, allowing for free fluid and cellul

79 We used gene targeting to validate candidate genetic factors.

80 We experimentally validated candidates from two sets of plant-associated g

81 To validate consensus equation in a perioperative setting a

82 We validate DAMACY by using three distinct datasets: in viv

83 cles in mixed systems is also experimentally validated, demonstrating both collision frequency (beta)

84 We validated DESMAN on a complex 50-species 210-genome 96-s

85 Cirrhosis, as defined by a validated diagnosis code algorithm.

86 We aimed to measure and validate differences in plasma concentrations of protein

87 seeds and bakery products was developed and validated down to a limit of quantification (LOQ) of 0.1

88 This model was validated estimating appropriate figures of merit.

89 protein excited states and rationally design validating experiments.

90 Experimentally validated FE models are combined for that purpose in one

91 equations in the moving wall domain with our validated flow solver.

92 Participants completed a validated food-frequency questionnaire and provided a fa

93 imaging protocols have not been systemically validated for absolute myocardial perfusion and coronary

94 asthma long-term control but have never been validated for AD.

95 The assay was validated for linearity, limit of detection, sensitivity

96 ipated during chemical reactions, previously validated for monitoring lipid oxidation in plant oils,

97 Level A IVIVCs were established and validated for predictability.

98 Genomic data were experimentally validated for PSMA expression-by quantitative reverse tr

99 dology identifies a number of TFs previously validated for reprogramming and/or natural differentiati

100 The new method was fully validated for the determination of both proteins and sma

101 raction method was developed, optimized, and validated for the elemental analysis of organic samples.

102 ty, the donor liver index, was developed and validated for the UK population of transplant recipients

103 nce (iSPR) biosensor assay was developed and validated for three Fusarium toxins, deoxynivalenol (DON

104 to be examined in a well-powered cohort with validated frailty status.

105 s to assess the change in symptoms using the validated Gastrointestinal Symptom Score (GIS(c)).

106 We investigated whether the association of a validated genetic profile risk score for obesity (GPRS-o

107 old under operating conditions of a recently validated gold catalyst for acetylene hydrochlorination.

108 R3, AHR and NMU as examples, we explored and validated how the genetic variations contribute to the p

109 Validating HSP72 inhibitors in cells is difficult owing

110 Here we describe an approach to functionally validate identified variants through differentiation of

111 uality of a subset of 111 CT examinations to validate image quality at the lower bound.

112 This study sought to validate in vivo DT-CMR measures of cardiac microstructu

113 ternally bootstrap validated, and externally validated in 1,547 patients in another study.

114 we generated a CNA-based classifier that we validated in 18 additional patients (testing set, 112 CT

115 redictive biomarker for AsiDNA treatment was validated in 43 tumor cell lines from various tissues an

116 Nomograms were externally validated in a cohort of 153 patients with OPSCC randoml

117 olic status of obese individuals was further validated in a cross-sectional cohort of 381 participant

118 y of the SMF stimulated oligodendrocytes was validated in a dorsal root ganglion microfluidics chambe

119 These findings should be validated in a larger study.

120 nial magnetic stimulation-guided regions was validated in a second sample of 108 patients and found t

121 Seventeen of these DMGRs were independently validated in a similar analysis of an external data set.

122 These predictions are validated in a spiking neural network model of the OB-PC

123 ng developmental trajectories in HR infants (validated in an analysis of 1,445 infants from represent

124 These findings were validated in an independent cohort of 40 patients.

125 The results from the training group were validated in an independent group of healthy human subje

126 o hundred forty-seven of these proteins were validated in an independent planned myocardial injury co

127 Results were validated in an independent population of asthmatic chil

128 Our findings were validated in both primary and metastatic models of pancr

129 Their utility is validated in examining protein S-persulfidation.

130 Multidimensional algorithms, which must be validated in primary and urgent care settings, may help

131 The involved pathways were validated in primary CD4(+) T cells, target cells for HI

132 The assay was validated in terms of selectivity, sensitivity, accuracy

133 SDS implementations have been experimentally validated in the near-IR.

134 Inhibitors of the proteasome have been validated in the treatment of multiple myeloma, with sev

135 This was validated in the two additional cohorts.

136 The reagents have been successfully validated in tomato (Solanum lycopersicum), tobacco (Nic

137 The bioreporters were further validated in vetch (Vicia hirsuta), producing similar re

138 es and has been extensively investigated and validated in vivo.

139 dimer-prone or monomer-prone conformations, validated in-solution, and introduced to molecular clone

140 ogen behavior in vivo, and the importance of validating in vitro studies of antibiotic effects with i

141 We validated increased expression of multiple miRNAs, inclu

142 last five years and the scores for all three validated instruments.

143 om whole exome sequencing individual's data, validated it on 1000 Genome Project and TCGA data (2700

144 etection capability of PECAN, and we further validate its detection with data-dependent acquisition a

145 ormal mathematical and graphic assessment to validate its suitability for these purposes.

146 for subphenotype identification in FACTT and validated its accuracy in the two cohorts in which we pr

147 In summary, we validated known and identified additional determinants f

148 With this rationale, this study presents a validated lipidomics platform to map the fecal lipidome,

149 We used a cross-validating machine learning method to select predictor v

150 ng, with which we predicted and subsequently validated many putative zDHHC17 interactors.

151 The validated method can be used to determine the purity of

152 widespread attention in drug discovery as a validated method to circumvent acquired resistance in on

153 data collection and analysis, and absence of validated methods combine to hamper the quantity and qua

154 s when using WUE measures to parameterize or validate models, and indicates key research directions n

155 To our knowledge, this is the first paradigm validating modulation of paxillin to inhibit angiogenesi

156 We have identified and validated multiple TFs influencing asthma treatment resp

157 nic drift events, pointing to experimentally validated mutations.

158 are prospectively recruited to an externally validated national outcome audit.

159 Here we present a validated numerical method for estimating diffusion, bin

160 When validated on 99 newly-discovered genes with pathogenic m

161 The framework has been validated on thousands of cancer samples, using gene exp

162 These data provide a comprehensive basis for validating (or not) laboratory mice as a useful and rele

163 risk factor for graft failure, and does not validate other risk factors for IC found in smaller stud

164 nfirming the theoretical method, and (ii) to validate our approach as function of temperature and of

165 Taken together, our results validate our enhancer identification pipeline and reveal

166 We further validate our findings through assessing the power and ac

167 We extensively validate our framework using existing computational tool

168 spectroscopy studies with purified proteins validate our MD predictions and corroborate the conclusi

169 We validate our model with high-speed experiments and prese

170 To validate our model, we systematically manipulated experi

171 We validate our predictions for 19 compounds using phonon c

172 DX) samples to predict pathway activity, and validated our approach of developing individualized trea

173 atocytes in vivo have been published, and we validated our approach using this control by confirming

174 nalysis of IOP and optic disc parameters and validated our findings in multiple sets of POAG cases an

175 uced and shown to kill P. aeruginosa thereby validating our pipeline.

176 The on-line method was validated over a concentration range of 0.1-0.6ngg(-1) o

177 In this study, we sought to validate PGS for QT interval in 2 real-world cohorts of

178 Our results validate Plk4 as a therapeutic target in cancer patients

179 We also validate previous suggestions that APOE, CHRNA3/5, CDKN2

180 nd-systolic dimension is incremental to well-validated prognostic scores in pulmonary arterial hypert

181 numerical simulations and, more importantly, validated quantitatively by single-cell data analysis of

182 unknown for a long time, due to a lack of a validated questionnaire to assess QoL in the NAR patient

183 restraint-were measured through the use of a validated questionnaire.

184 Using all datasets, we validated recently identified loci associated with CAD.

185 neural reward activation in the context of a validated reward task at 10.00 h, 14.00 h, and 19.00 h i

186 igue, physical, and mental performance using validated scales during 2 operative days: 1 day without

187 At each observation, ERI was measured using validated scales, and ambulatory blood pressure (BP) was

188 tests, vital signs, electrocardiograms, and validated scales.

189 There is a lack of simple and validated severity assessments that are feasible for cli

190 Dry eye disease was defined from the validated Short Questionnaire for Dry Eye Syndrome (SQDE

191 tional predictions, which were biochemically validated, show an extensive overlap of regulatory circu

192 e and ripening-modulated genes confirmed and validated sHSP transcript profile patterns.

193 mal genes with CM-specific survival and then validated significant SNPs in another genome-wide associ

194 we observe do not readily form in previously validated simulations; nor have they been predicted theo

195 Thus, mAb against well-validated solid tumor targets, such as the epidermal gro

196 tructured clinical examination and completed validated symptom questionnaires and the Clinical HIV-As

197 ys a central role in fat metabolism and is a validated target for weight loss.

198 NA sequence being the only input, we further validate that the nonconsensus nucleotide triplet code c

199 alpha2:beta2 complex by HYSCORE spectroscopy validate that the perturbed conformation of Y731 in R411

200 By using novel engineered DBP immunogens, we validate that the prime targets of protective immunity a

201 Experimental and theoretical results validate that, due to its high sensitivity to the spatia

202 Importantly, in silico modeling validated that this Ser-to-Arg mutation could alter the

203 ine but also dissects their binding mode and validates that berberine indeed suppresses beta-catenin

204 We attempted to validate the association between variants in these genes

205 In this study, we aimed to validate the association of 8 reported significant loci

206 ultiple postoperative measures are needed to validate the effect of these potential biomarkers of fib

207 Additional larger studies are needed to validate the effects of prolonged anakinra on peak Vo2 a

208 DH1 expression and catalytic site disruption validate the essentiality of GAPDH1 in intracellular rep

209 We went on to validate the findings of WES using 151 leprosy cases and

210 action potential within single neurons, and validate the imaging technique with the traditional patc

211 To validate the in vivo relevance of genetic dependencies o

212 affinity purification and immunoblotting to validate the interaction between STAT5A and PDC subunits

213 -three counterfeit samples were also used to validate the method.

214 To validate the MSERg method, we aligned 45 pairs of in viv

215 In addition, we validate the possibility of employing LR time-dependent

216 Our results validate the premise that stereospecific but necessarily

217 mber checking with patients and families, to validate the process and outcome of the guideline develo

218 We validate the protocol with the aid of enumerated good-sc

219 To further validate the Q3 responses, a systematic electronic chart

220 This study sought to validate the RD-OGI Score in an independent cohort of pa

221 spective, large-scale multicenter studies to validate the result are warranted.

222 tic circular dichroism (MCD) spectroscopy to validate the results of TD-DFT calculations.

223 The reported findings validate the self-immolative nanoparticles as delivery v

224 We validate the technique against measurements performed wi

225 We validate the theory by measuring the pH response of an e

226 Finally, we validate the ubiquitous nature of urea-aromatic stacking

227 SCLC cells in vivo Collectively, our studies validate the utility of the Lu-iPSC model for elucidatin

228 A growing body of evidence has validated the diagnostic accuracy of FFRCT techniques co

229 ne miRNA diagnostic value for SZ and further validated the meta-analysis results.

230 A standard addition experiment has validated the method.

231 the associated metabolic profiles, and then validated the models using data and samples from the INT

232 mplified clones from the same population, we validated the procedure as a firm foundation for standar

233 imated sulphur intake from food diaries, and validated the results with the use of a duplicate diet a

234 age cells expressing Notch receptors further validates the human thymus as a DC-poietic organ, which

235 s work presents the experimental proof which validates the hypothesis of a pH change during electroom

236 This validates the point that the relationship of evolutionar

237 This study validates the prognostic power of RETREAT, which may hel

238 Our approach also validates the promising combination of plant engineering

239 onships extracted by PSSM-RT and the results validates the usefulness of PSSM-RT for encoding DNA-bin

240 Validating the accuracy of billing claim codes used duri

241 e well with the relevant crystal structures, validating the computational protocol.

242 ario, our method performs reasonably well in validating the existence of a master regulator when the

243 peptides acetylated at lysine 14 (H3K14Ac), validating the importance of this specific acetylation m

244 The aim of this study was to validate their prognostic use and reproducibility across

245 ses in which the evidence is insufficient to validate their surrogate status.

246 However, there are limited data validating their vaccine efficacy.

247 This remarkable field experiment has both validated theoretical models of Wolbachia population dyn

248 We observe experimentally, and validate theoretically, that the inward motion of the ph

249 c Hedgehog (SHH) morphogen pathways are well-validated therapeutic targets in cancer, including medul

250 ramingham Heart Study and their spouses, and validated these findings in plasma samples from 1421 par

251 We validated these pathways in primary human CD4(+) T cells

252 We cross-validated these predictions by reconstituting the bindin

253 ures of unbound and H1-bound nucleosomes and validated these structures by site-directed protein cros

254 Validating these associations in vivo will lead to new d

255 If prospectively validated, these multivariable associations may help tar

256 Future research should validate this checklist in other settings and compare it

257 A prospective trial to validate this concept is warranted.

258 To validate this DsbA-mycoredoxin cluster, we also characte

259 Here, we validate this electrochemical detection strategy using c

260 We first used simulations to validate this method by showing that it yields unbiased

261 To validate this prediction, we demonstrated that the modul

262 To validate this prediction, we perform electrophysiologica

263 ectly identify the causal variants that were validated through complementation assays.

264 However, these scales have never been validated through factor analysis.

265 nfirmed device's high performance is further validated through its integration in three different sys

266 solid- and solution-phase synthesis that we validated through performing the first chemical synthesi

267 line or carbachol paradigm was developed and validated to determine alpha4/beta2 subunit stoichiometr

268 erate hypothesis which can be experimentally validated to improve our understanding of what triggers

269 a new analytical procedure was developed and validated to measure tobacco-related alkaloids, carcinog

270 mple fusion method is developed, tested, and validated to produce homogeneous, flux-free glass beads

271 This relatively strong correlation validates tooth form as a proxy for neutral genomic mark

272 Dynamic PET data were analyzed using the validated two-tissue compartment model with arterial pla

273 g the initial screening, and we subsequently validated upregulation of miR-139-5p in two independent

274 s many of the issues involved in testing and validating urban simulation models involving spatial dat

275 nation, and model performance was internally validated using 10-fold cross-validation.

276 The results were validated using a certified reference material (NIST SRM

277 nertial cavitation behavior was designed and validated using a dual-transducer system operating at th

278 using CCS values of 205 small molecules and validated using a set of 131 pesticides.

279 -, YPtAs-, UGeTe-, and LaPtSi-type) and then validated using an additional 519 compounds.

280 r recent years, and the model prediction was validated using an independent data set from England and

281 and dynamic pH conditions, respectively, and validated using an independent method.

282 These findings were validated using data from colorectal cancer patients (n

283 self-organization of social-insect colonies, validated using data from four continents, which demonst

284 The theoretical model was validated using glycerol reference solutions.

285 Differential gene expression was validated using NanoString technology.

286 1 and depleted in breast cancer 1 (DBC1) was validated using RNA pull-down and RNA immunoprecipitatio

287 metastasis, such as HAND2-AS1, were further validated using RNAi-based loss-of-function assays.

288 he accuracy and reliability of the method is validated using simulated data sets.

289 Model outcomes were validated using the PBC Global Study.

290 to any rotationally symmetric oligomers, was validated using the structures of the Fas death receptor

291 The performance of the model was validated, using literature data for enzyme and microbia

292 discriminant analysis, and the results were validated with an independent patient set.

293 The algorithm is validated with approximately 3 million rides extracted f

294 Virgin Islands over 7 years (2004-2011), and validated with data from 2012 to 2015.

295 The physical maps were validated with FISH and genetic mapping of SNP markers d

296 First validated with standard synthetic membranes and then dem

297 The performance of the proposed technique is validated with two different spectroscopic techniques (R

298 structed knowledge graphs were evaluated and validated, with permission, against Google's manually-co

299 ients in human plasma, we introduce a novel, validated workflow for the determination of 14 fat-solub

300 We validated ZBTB20, CELF2, PARD3, AKAP13 and WAC, which we