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1 ive, cross-sectional, comparative instrument validation study.
2 o derive the model and 30% were used for the validation study.
3 e USDA Automated Multiple-Pass Method (AMPM) Validation Study.
4 ir validity and reliability during a 12-week validation study.
5 Hospital Zurich (Zurich, Switzerland) in the validation study.
6 l corneas in a 3-stage discovery/replication/validation study.
7 Questionnaire design and validation study.
8 , accuracy and recovery were obtained in the validation study.
9 re confirmed differentially expressed, after validation study.
10 < 0.05 and seven with p values < 0.01 in the validation study.
11 n providing the basis for a biomarker-driven validation study.
12 y reducing the mean squared error in a cross-validation study.
13 al dysfunction, were included in the initial validation study.
14 nfirms the advantages suggested by the cross-validation study.
15 ted as part of this comprehensive microarray validation study.
16 Prospective, cross-sectional validation study.
17 The AUC was 0.79 in the independent validation study.
18 patients from 2 centers were included in the validation study.
19 if data on the outcome are available in the validation study.
20 th factor 1 (FGF-1) was selected for further validation study.
21 main study by using variables observed in a validation study.
22 is finding was further confirmed by a direct validation study.
23 ded data on covariates available only in the validation study.
24 nding by estimating two additional PS's in a validation study.
25 Development and validation study.
26 consistent performance in the out-of-sample validation study.
27 , 41 MIS and 76 ISM) took part in the MC-QoL validation study.
28 These findings were corroborated in the validation study.
29 and 1.13, 0.90-1.40, respectively) or in the validation studies.
30 itor that is well suited for further in vivo validation studies.
31 setting filtering parameters, and designing validation studies.
32 ampi from postmortem MS brains and performed validation studies.
33 suited as tool compounds for further in vivo validation studies.
34 associations have been tested in independent validation studies.
35 y in derivation samples, and the scarcity of validation studies.
36 explained by differences in case mix in the validation studies.
37 icipates future large-scale consortium-based validation studies.
38 des candidate glaucoma biomarkers for future validation studies.
39 cell line (231-BR) was used additionally in validation studies.
40 s to confirm discoveries through independent validation studies.
41 ociceptive processes and in pain gene target validation studies.
42 nd performed this task with 100% accuracy in validation studies.
43 , DYS393, DYS439) was developed and used for validation studies.
44 ort, we conducted a systematic review of the validation studies.
45 n, inconsistent findings, and lack of proper validation studies.
46 as verified through extensive simulation and validation studies.
47 ommended depending on the results of further validation studies.
48 n some variation in results seen in previous validation studies.
50 only after careful consideration with method validation studies; (2) lot control and prescreening sam
51 ver a 1-year period in the women's Lifestyle Validation Study (2010-2012), conducted among subgroups
53 eparate randomized, single-blind, cross-over validation study, 6 additional healthy men ingested a hi
55 ve (FFR), from early experimental studies to validation studies against indexes of ischemia, to clini
59 ests present and suggest strategies, such as validation studies and development of culture-independen
60 d be placed on conducting different types of validation studies and multiple studies with different s
61 imple assay may find broad utility in target validation studies and preclinical drug development prog
62 >1.0) during the lower-dose (LPS 0.6 ng/kg) validation study and 51 of 85 (59% [49-70]) were induced
63 ated persons, after adjustment for X, in the validation study and assuming a range of plausible value
64 lized disease subsets, large cross-sectional validation studies, and longitudinal studies, with and w
65 ood discrimination (AUROC > 0.8) in external validation studies, and sensitivity and specificity rang
66 supercede any of the current methods because validation studies are lacking, informative results are
67 en promising; however, the results of larger validation studies are necessary before being incorporat
76 visions and enhancements will be required as validation studies are undertaken in varying diseases an
85 Meta-analysis could only be performed for validation studies because studies on prognostic perform
86 the importance of performing a well-designed validation study because it allows for understanding and
87 g therapy, it is necessary to pursue further validation studies before or during pivotal phase IIB or
89 roteins then were evaluated in a blind cross-validation study by using an additional 106 healthy fema
95 this widespread use, accuracy and precision validation studies comparing noninvasive blood pressure
96 arly amyloid-beta deposition is unknown, and validation studies comparing Pittsburgh compound-B thres
97 e of the art using benchmark datasets; (2) a validation study comparing the results of our approach w
104 t of the TGF-beta/SMAD4 network, and genetic validation studies confirmed the cooperative roles of Pt
107 Transcriptional profiling and functional validation studies demonstrate that these include effect
110 ontrol subjects and 183 HF patients, and the validation study enrolled 63 control subjects and 218 pa
113 ancer and paves the way for prediction model validation study followed by pivotal clinical validation
114 measure of PM exposure should conduct local validation studies for different stove/fuel types and se
115 ase, a systematic analysis of verbal autopsy validation studies for malaria, and recent studies (2010
118 y (LPA) encountered during a feasibility and validation study for the introduction of this rapid drug
120 developed and are undergoing early clinical validation studies.Further clinical studies including an
121 The 201 participants in the prospective validation study had a mean age of 84 years, and 28% had
124 rediction equations have been published, but validation studies have shown that these equations tend
125 y scores have been proposed, but findings of validation studies have shown that they are not adequate
128 of the aggregate and perform in-depth cross-validation studies; (ii) second, we propose a new approa
133 s MR-1 and carried out successful functional validation studies in Escherichia coli and Bacillus subt
136 by TXNIP by microarray analysis, followed by validation studies in INS-1 beta cells, islets of Txnip-
137 cute ischaemia in the ageing brain and merit validation studies in larger cohorts, particularly in re
141 t has now become necessary to pursue further validation studies in the run-up to or during pivotal tr
142 llary nodes treated with adjuvant tamoxifen; validation studies in this population led to its approva
148 performed a retrospective cohort study and a validation study in patients with cancer-associated VTE
149 nome-wide association study, followed by two validation studies, in 3,173 Japanese patients with EGFR
150 he acquired data as well as the results of a validation study, in which the repeatability, specificit
152 g HLA imputation, followed by a multi-ethnic validation study including east Asian and European popul
159 ranslation of successful target and compound validation studies into clinically effective therapies i
161 rformed a 19-month, prospective, multicenter validation study involving 49 clinical sites, 3789 patie
174 eria on the basis of emerging trial data and validation studies of the Prostate Cancer Clinical Trial
177 le, Spain (estimation cohort), followed by a validation study of 114 consecutive patients with cirrho
178 -4) for either trait were taken forward to a validation study of 123 ethnically diverse men from Chic
182 0(-4) and P = 4 x 10(-4), respectively) in a validation study of 4,106 individuals with rheumatoid ar
184 dy were used as a "molecular signature" in a validation study of an additional 26 subjects and predic
188 a retrospective, multicenter, double-blinded validation study of eight BE progression prediction meth
189 independent, prospectively designed clinical validation study of Recurrence Score, with prespecified
191 fertility treatment, the authors conducted a validation study of the assisted reproductive technology
192 ed 1147 patients with IgAN from the European Validation Study of the Oxford Classification of IgAN (V
193 lysis of collected data from the prospective validation study of the Preschool Confusion Assessment M
195 DLINE and Embase (until October 1, 2012) for validation studies on instruments measuring the clinical
199 magnetic resonance imaging and histological validation studies performed in canines demonstrated tha
201 y questionnaires (FFQs), using data from the Validation Studies Pooling Project, comprising 5 large v
203 Genetic, transcriptomic, and functional validation studies revealed an important role for HIF-1a
207 ng EGFR bypass genes, together with targeted validation studies, reveals EGFR-independent activation
209 s the analysis results from the main and the validation study samples, where the propensity score adj
216 ut none were extensively validated, and some validation studies showed LRs similar to estimates for i
219 n of sequence motifs, and an extensive cross-validation study showed that A-GLAM's model was robust a
227 measured confounders using a cross-sectional validation study that lacks information on the disease o
229 erformance of MSC was evaluated in a blinded validation study that used prespecified risk groups.
230 f 775 healthy women in the Women's Lifestyle Validation Study that was conducted within the NHS (Nurs
231 we show, using RNAi screening and subsequent validation studies, that NRP1-mediated endocytosis of Ce
240 n new drug development for PD, both in early validation studies to assess drug dosing and to determin
241 impairment levels and conducted a series of validation studies to build a patient-centered multi-ite
243 ficant challenges to be addressed by further validation studies to define precisely the limitations a
246 ge design was conducted by first proposing a validation study to calibrate CPI between a senior perio
247 large, training-testing, multi-site, blinded validation study to characterize the performance of seve
249 microarrays produced were used in a blinded validation study to determine whether annexin I, PGP9.5,
251 enome-wide association study data sets and a validation study totaling 10 204 cases and 107 766 contr
252 enome-wide association study data sets and a validation study totaling 10 204 cases and 107 766 contr
255 using a focused RNAi analysis combined with validation studies using pharmacological inhibitors.
264 The sensitivity of the mCIM observed in the validation study was 99% (95% confidence interval [95% C
277 ghly polygenic trait and, using quantitative validation studies, we showed that natural variation in
278 equence analysis and subsequent experimental validation studies, we uncovered seven AR variant transc
280 ause of death was 149; however, based on our validation study, we estimate the true number was 78 (ra
287 Based on data from 172 patients, a series of validation studies were conducted, including item and fa
289 been established for these instruments, and validation studies were only conducted in a limited numb
292 garding calibration of CPI obtained from the validation study were 66% and 85% for sensitivity and sp
293 ionally, similar observations were seen in a validation study where SYK, LYN and PTPN6 were markedly
297 ls, a large percentage of individuals in the validation study with small nodules (<1 cm) were assigne
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