ライフサイエンスコーパス: valine

1 ced branched-chain AAs (leucine, isoleucine, valine).

2 predominant being phenylalanine, lysine and valine.

3 o includes l-methionine, l-isoleucine, and l-valine.

4 f the oxazoline rings were prepared from (S)-valine.

5 ino acids were arginine, leucine, lysine and valine.

6 ne in the rat enzyme is mutated to the human valine.

7 ophobic amino acids isoleucine, leucine, and valine.

8 n approach including a traceless ligation at valine.

9 educed catabolic activity for isoleucine and valine.

10 o acid change at position 89 from alanine to valine.

11 holoenzyme exhibits increased resistance to valine.

12 1.54 (95% CI 1.28-1.84, p = 4.2 x 10-6) for valine.

13 serine, threonine, tryptophan, tyrosine, and valine.

14 2.29 (1.31-4.01), leucine 1.80 (1.10-2.96), valine 1.77 (1.07-2.92), tyrosine 2.13 (1.20-3.78), and

15 xy-D-fructose-1-yl) amino acid (amino acid=L-valine (1), L-leucine (2), L-isoleucine (3), L-tryptopha

16 domain of the P and V proteins-tyrosine 110, valine 112, and histidine 115-that function to retain ST

17 feldt-Jakob disease expressing prion protein valine 129.

18 C terminus, producing three forms ending in valine-175, histidine-177, or serine-178.

19 ation by inducing KPNA1 degradation and that valine-19 in Nsp1beta correlates with the inhibition.

20 with human alpha5(V9)'(S) subunits bearing a valine 290 to serine mutation in the 9' position of the

21 alanine (2a), isoleucine (2b), proline (2c), valine (2d), phenylalanine (2e), glycine (2f) and leucin

22 ate specificity and of histidine-153 and the valine-31 to proline-37 loop in catalysis.

23 Simultaneously converting alanine 355 and valine 377 of FAR5 to the corresponding FAR8 residues, l

24 We identified two contiguous amino acids, valine-381 and serine-382, located in the C-linker carbo

25 f 11 substitutions of the S1 subsite residue valine 459 in the Plasmodium falciparum aminopeptidase P

26 lorine was found to first react quickly with valine (5.4 x 10(4) M(-1) s(-1)) to form N-monochloroval

27 e two residues to those in Pto (histidine-49/valine-51) did not restore recognition of AvrPto.

28 Interestingly, dileucine 594/595 and valine 597 residues present in the Ldgp63 C-terminal dom

29 The valine 66 to methionine (Met) polymorphism within the br

30 ong schizophrenia patients who have the BDNF valine 66 to methionine (Val66Met) genotype (Val/Val).

31 er proceeds via the leucine 69 (Leu(69)) and valine 68 (Val(68)) residues.

32 t transmembrane cleavage of VEGFR1 occurs at valine 767 and that a switch from valine to alanine at t

33 racterize Nva and differentiate it from Val (Valine), a systematic study was conducted using hot elec

34 analysis indicated that mutation of E295 to valine, a noncoordinating residue, results in a decrease

35 Replacement of Phe(523) with alanine or valine abolishes the ability of the helicase to unwind D

36 tion and, to a lesser extent, isoleucine and valine acquisition.

37 olution of the genetic code four amino acids-valine, alanine, aspartic acid, and glycine-were coded b

38 tants in which threonine 191 was replaced by valine, alanine, or proline.

39 Individuals with the BDNF Val/Val (valine allele) polymorphism showed better memory perform

40 or replacement of isoleucine with alanine or valine alters the ability of the mutant RdRps to incorpo

41 the FSS13025 strain because of an alanine-to-valine amino acid substitution at residue 188 in NS1.

42 ydroxybutyrate/3-aminoisobutyrate, tyrosine, valine and 3-hydroxyisovalerate exhibited the highest st

43 rms favorable packing between the engineered valine and a target uracil base.

44 sts are derived from the abundant amino acid valine and are prepared in large quantities in four step

45 geometry we can increase ion intensities for valine and by tuning the plasma power we can also select

46 for initiation of CaDPA release with both l-valine and dodecylamine but not with faster CaDPA releas

47 itrate, tyrosine, phenylalanine, isoleucine, valine and glucose were identified and considered as pot

48 ion, EhCP4 displayed a unique preference for valine and isoleucine at P2.

49 ing analyses supported the transformation of valine and isoleucine to isobutylamine and 2-methylbutyl

50 n amino acid degradation (named for leucine, valine and isoleucine) and seed development was limited

51 coats, decreased storage reserves, elevated valine and leucine, and reduced germination rates.

52 glucose at 120 min, and leucine, isoleucine, valine and proline at 90 and 120 min, whereas infants fe

53 leucine/isoleucine, phenylalanine, tyrosine, valine and proline significantly associated with obesity

54 of key metabolites like proline, asparagine, valine and several flavonoids.

55 ression results revealed a possible role for valine and/or isoleucine in CI tolerance.

56 By manipulating the number and position of valines and alanines in the peptide sequence, we found t

57 BCAAs (i.e., isoleucine, leucine, and valine) and their downstream metabolites (i.e., alanine,

58 ected amino acids, FMOC-l-leucine and FMOC-l-valine, and a dipeptide, N-acetyl-l-valyl-l-leucine (N-A

59 ated with a depletion of lipid, cholesterol, valine, and alanine levels, which may provide informativ

60 nched chain amino acids leucine, isoleucine, valine, and alloisoleucine were significantly improved i

61 We find enrichment of glycine, valine, and arginine as both individual amino acids and

62 etween 200 mM and 1 M l-alanine and 100 mM l-valine, and at 1 M l-alanine, the rates of germination o

63 BM samples were higher in threonine, serine, valine, and lower in orotic acid and urea.

64 VK (titin domain rich in proline, glutamate, valine, and lysine) region of titin.

65 in (titin region rich in proline, glutamate, valine, and lysine), of the titin springs.

66 ss-related amino acids (isoleucine, leucine, valine, and proline), sugars, intermediates of the trica

67 d essential amino acids, such as tryptophan, valine, and threonine, were determined in yacon syrup.

68 stidine, phenylalanine, leucine, isoleucine, valine, and tyrosine) were assessed with the use of high

69 The proline-, glutamate-, valine-, and lysine-rich (PEVK) domain of the giant musc

70 d-chain amino acids isoleucine, leucine, and valine are associated with Alzheimer's disease (AD).

71 amino acids (BCAAs) leucine, isoleucine, and valine are elevated in maple syrup urine disease, heart

72 amino acids (BCAAs; leucine, isoleucine and valine) are elevated in the blood of obese, insulin-resi

73 acids (BCAAs; i.e., isoleucine, leucine, and valine) are strongly associated with higher type 2 diabe

74 e internally flexible compared to those with valine as the first amino acid.

75 3-HIB), a catabolic intermediate of the BCAA valine, as a new paracrine regulator of trans-endothelia

76 lution of the BCAAs isoleucine, leucine, and valine, as well as 13 other amino acids, including ornit

77 ncentrations of the diabetes-associated BCAA valine at 6 mo independent of the weight change.

78 Valine at position 11 also was associated with higher al

79 Patients with RA and valine at position 11 of HLA-DRB1 had the strongest asso

80 nd feet were 48% of noncarriers (150/314) of valine at position 11, 61% of heterozygote carriers (130

81 G2 mutant harboring glutamic acid instead of valine at position 30 (V30E) failed to induce cell death

82 (TTR) with a substitution of methionine for valine at position 30 (V30M).

83 ncode functional (PAV: proline, alanine, and valine at positions 49, 262, and 296, respectively) or n

84 pped (e.g. 'glutamic acid was substituted by valine at residue 6').

85 d the moderate risk RET p.Val804Met (protein valine at residue 804 replaced by methionine) genetic mu

86 P; further, the replacement of leucines with valines at "a" and "d" positions of melittin-heptads dra

87 dium site residue Asn 131 to an alanine or a valine augments constitutive beta-arrestin-mediated sign

88 Chiral C(2)-symmetrical proline- and valine-based amides and their Zn(II) complexes were desi

89 responding carboxyl and amino termini of (S)-valine-based bis-thiazole and monothiazole derivatives w

90 ao function in mutant screens, and develop D-valine-based methods to manage the spread of transgenic

91 al capacity of Schwann cells to metabolize D-valine because of the difference in expression of a D-am

92 Valine betaine and glutamine betaine, the latter never r

93 xamined flours, whereas an uncommon betaine, valine betaine, and glutamine betaine were present only

94 Only alanine, glutamate, isoleucine, and valine, but not leucine, were increased in NAFLD-NO subj

95 se phenotype and resulted in substitution of valine by alanine at position 933, within the catalytic

96 ne 1768 to aspartic acid and leucine 1331 to valine) by obtaining whole-cell patch clamp recordings i

97 Studies evaluating flux through the valine catabolic pathway in humans should account for th

98 ating with synaptic vulnerability, including valine catabolism and rho signalling pathways.

99 since it was also found to be essential for valine catabolism, supporting its more recent annotation

100 HIBCH is unique to valine catabolism.

101 protease-cleavable linker, maleimido-caproyl-valine-citruline-p-amino-benzyloxy carbonyl (mcVC-PABC).

102 examine the effect of the protease-cleavable valine-citrulline [VC(S)] linker on ADC efficacy.

103 caproyl-monomethyl Auristatin F (mcMMAF) and valine-citrulline-monomethyl Auristatin E (vcMMAE) at in

104 sium channel Kv1.1 converts an isoleucine to valine codon for amino acid 400, speeding channel recove

105 -MDR1-3HA (a mutant that carries a different valine codon in position 3435).

106 Its replacement with leucine or valine completely abolished activation with paclitaxel w

107 Valine concentrations increased by 40% in response to in

108 hough there is indeed evidence for alternate valine conformers and variable water content.

109 GerA GR's responsiveness to its germinant l-valine, consistent with there being some type of interac

110 ltaneously restrict fibroblast overgrowth (D-valine), contained in DMEM.

111 etabolites (e.g. glucose, glycogen, leucine, valine, creatine, carnitine, lactate, nucleosides) were

112 that the major product, MftA*, is a tyramine-valine-cross-linked peptide formed by MftC through two S

113 acetone, ursodeoxycholic acid, tryptophan, L-valine, cycloserine, hypoxanthine, and 4-O-Methylmelleol

114 e show that disruptions in the mitochondrial valine degradation pathway affect seed development and g

115 ole of two putative mitochondrial enzymes in valine degradation using insertional mutants.

116 ared to transaminase IlvE and NADH-dependent valine dehydrogenases, the evolved glutamate dehydrogena

117 HSCs failed to proliferate when cultured in valine-depleted conditions.

118 generated in situ from a readily accessible valine-derived aminophenol and a Z- or an E-gamma-substi

119 Conversion of Gly-294 to valine eliminates a rate limiting conformational change

120 Finally l-valine esters with ester variation lead to potent, stabl

121 vitro and catalyzes formation of a tyrosine-valine ether cross-link in the protein scaffold.

122 of the protein scaffold, yielding a tyrosine-valine ether cross-link.

123 infant found to have a phenylalanine 229 to valine (F229V) substitution in V2R.

124 >G transition that encodes a substitution of valine for a highly conserved methionine (p.Met184Val) i

125 ATTR can result from substitution of valine for isoleucine at codon 122 of the transthyretin

126 in this protein showed that substitution of valine for the phenylalanine residue four residues downs

127 , asparagine, glutamine, proline, serine and valine) for Sudanese food.

128 nts for all reactions in the chlorination of valine, for the first time, using experimental results a

129 uished electrochemical response to fructosyl valine (FV) which demonstrates a promising application f

130 leucine, leucine, methionine, phenylalanine, valine, GABA, glutamine, alanine, glycine and taurine we

131 ding on pH, opens at either the histidine or valine gate is only partially supported by the simulatio

132 of lactate, choline, or amino acids such as valine, glycine, or glutamate increased with time, where

133 motifs and genetic linkage to members of the valine-glycine repeat protein G (vgrG) genes.

134 Here, we report that two T6SS encoded valine-glycine repeat protein G (VgrG) paralogs in Agrob

135 linked to hemolysin-coregulated protein and valine-glycine repeat protein G genes from type VI secre

136 Valine-glycine repeat protein G is required for inhibito

137 secretion system (T6SS-5) and its associated valine-glycine repeat protein, VgrG5.

138 Conversion of Gly-336 to valine has its main effect on the Kd of serine binding t

139 (BCAAs), including leucine, isoleucine, and valine, has shown potential benefits for the metabolic p

140 ture of methionine homozygous and methionine-valine heterozygous over time.

141 aline to glycine mutation at codon 176, with valine homozygosity at polymorphic codon 129.

142 s preliminary report suggests that CETP V405 valine homozygosity is associated with slower memory dec

143 prion protein gene (PRNP) from predominantly valine homozygous to a mixed picture of methionine homoz

144 A mutation of isoleucine 335 to valine (I355V) in hSLC2A9 can reduce fructose transport

145 n amino acids L-isoleucine, L-leucine, and L-valine (ILV) activate CodY both in vivo and in vitro, an

146 phatic amino acids [isoleucine, leucine, and valine (ILV) clusters] were found to experience strong w

147 of large clusters of isoleucine, leucine and valine (ILV) side chains located in the alpha7(betaalpha

148 the availability of isoleucine, leucine and valine (ILV), and GTP.

149 phatic side chains, isoleucine, leucine, and valine (ILV).

150 nd/or C103 with the beta-branched amino acid valine impairs the structural flexibility of the TMD in

151 line, phenylalanine and tyrosine (instead of valine in B2088) displayed better synergism compared to

152 Hence, an evolutionarily conserved valine in EGFr-8 is essential for ligand selectivity and

153 NAM binding causes displacement of a valine in GluN2A and the resulting steric effects can be

154 These findings indicate a critical role for valine in HSC maintenance and suggest that dietary valin

155 In fact, mutation of this valine in human CYP1B1 to the leucine present in the rat

156 with glycine, alpha-l- or beta-alanine and l-valine in pH 7.0 phosphate buffer at ca. 100 degrees C.

157 At V319C, the equivalent of valine in the conserved Kv proline-valine-proline (PVP)

158 The E11 valine in the distal heme pocket of either the alpha- or

159 d-chain amino acids leucine, isoleucine, and valine in this acute study.

160 nines in the peptide sequence, we found that valines increase the stiffness of the gel, while additio

161 acid change at residue 19 from isoleucine to valine induced KPNA1 degradation.

162 Mutation to nonphosphorylatable valine inhibited the Rvs167 interaction, while both S599

163 crease in IgG(1) binding affinity, whereas a valine insertion in the FcgammaRI FG-loop ((171)MVGKHRY(

164 ts, administering tyrosine, phenylalanine or valine IP 60min prior to harvesting of blood, CSF or bra

165 Here we report that the essential amino acid valine is indispensable for the proliferation and mainte

166 Although valine is similarly hydrophobic to leucine and phenylala

167 the synthesis of branched-chain amino acids (valine, isoleucine and leucine) were also absent, but ge

168 spectively) or non-functional (AVI: alanine, valine, isoleucine at positions 49, 262, and 296, respec

169 Serum values for a-amino-butyric acid, valine, isoleucine, leucine, tyrosine, phenylalanine, or

170 ringent set of aliphatic side chains such as valine, leucine, and isoleucine of putative substrates.

171 s in four metabolism pathways: beta-alanine; valine, leucine, iso-leucine; aminoacyl-tRNA; and alanin

172 lete pathways for biosynthesis of histidine, valine, leucine, isoleucine, lysine and proline pre-dete

173 The serum levels of valine, leucine, isoleucine, tyrosine, and phenylalanine

174 s are tolerated including those for alanine, valine, leucine, methionine, lysine, phenylalanine, tyro

175 ino aldehydes derived from glycine, alanine, valine, leucine, phenylalanine, isoleucine, serine, tryp

176 vitreous the amino acids implicated in MSUD (Valine, Leukine Isoleukine), were within normal range.

177 he metabolism of branched chain amino-acids (Valine, Leukine, Isoleukine).

178 and one SNP associated with both leucine and valine levels at genome-wide significance.

179 o 48.72 (36.28-64.84) microM (P < .001), and valine levels increased from 122.56 (95.63-140.61) micro

180 ding protein of the leucine, isoleucine, and valine (LIV) branched-chain amino acid transport system,

181 ein kinase A sites and the proline glutamate valine lysine (PEVK) S26 protein kinase C sites, but hyp

182 amino acids 3 times/d (leucine, isoleucine, valine, lysine, and threonine) (HFrAA) or with 3 g fruct

183 Initial compound optimization identified the valine-m-tyrosine-piperazic acid tripeptide (Val-m-Tyr-P

184 ethylpropanoic acid acyl chains derived from valine metabolism.

185 Studies of mice suggest that the valine metabolite 3-hydroxyisobutyrate (3-HIB), fibrobla

186 uire supplementation of leucine, isoleucine, valine, methionine, and threonine and modestly require t

187 rine, glycine, threonine, alanine, tyrosine, valine, methionine, lysine, isoleucine, leucine, phenyla

188 e structurally variant amino acids, glycine, valine, methionine, phenylalanine and cysteine were exam

189 hboring LRRFIP2, and marked by an isoleucine-valine missense variant in MLH1.

190 VBC that previously ingested 500 pmol of the valine-modified chloroplastic ATP synthase gamma-subunit

191 exhibiting similar UVPD changes whereas the valine mutation was significantly different.

192 ce revealed that the D166V (Aspartate166 --> Valine) mutation-induced changes in heart morphology and

193 medical food and supplemental isoleucine or valine (n = 5 of 29), or the use of natural protein alon

194 Here, we show that the polymerization of valine-NCA in the presence of fatty acids yields acylate

195 n arginine and oleic acid in the presence of valine-NCA, partitions spontaneously into vesicle membra

196 With glycine, alanine, valine, norvaline, and tert-leucine, HAT occurs from the

197 ts, obtained by substituting the position-74 valine of the -sensitive NiFe hydrogenase from Desulfovi

198 ine, hydroxyproline, leucine, isoleucine and valine on the negative side of PC1 and porcine gelatin w

199 e number of helix-destabilizing, ss-branched valine or isoleucine residues within the TMD restores no

200 ty of these prodrugs, an amino acid residue (valine or lysine) or a phosphate group was introduced on

201 ered when glycine 4864 is replaced by either valine or proline, the former preventing channel opening

202 ls and microbes, to either select against (D-valine) or for (D-alanine) cells containing transgenic p

203 rminant receptor (GR)-dependent germinant, l-valine, or a non-GR-dependent germinant, dodecylamine.

204 eties, such as methyl groups of isoleucines, valines, or leucines.

205 on and characterization of this new thiazole-valine peptidomimetic will facilitate design and synthes

206 ated if TTT-28, a newly synthesized thiazole-valine peptidomimetic, could reverse ABCB1-mediated MDR

207 This valine-phenyalanine cross-link, produced in an oxygen-de

208 sential amino acids: tryptophan, isoleucine, valine, phenylalanine, leucine, threonine, lysine, histi

209 e are a FCGR3A dimorphism resulting in CD16A-valine/phenylalanine-158 allotypes with different IgG af

210 ry minor role in the processing of all three valine polycistronic transcripts.

211 isease phenotype is modified by a methionine/valine polymorphism at codon 129 of the prion protein ge

212 ease duration, atrophy, codon 129 methionine valine polymorphism, Medical Research Council Rating Sca

213 Choline, dimethylarginine, arginine, valine, proline, serine, histidine, creatine, carnitine,

214 veral voltage-gated channels share a proline-valine-proline (proline hinge) sequence motif at the int

215 valent of valine in the conserved Kv proline-valine-proline (PVP) motif, Cd(2+) forms intrasubunit co

216 elated gene (hERG) channels lack the proline-valine-proline motif and the location of the intracellul

217 he inner S6 helices near a conserved proline-valine-proline motif, which introduces a kink that allow

218 core genes encoding glycerate kinase (glxK), valine-pyruvate transaminase (avtA), superoxide dismutas

219 The leucine- and valine-raising allele was not associated with AD (p = 0.

220 uM and 2 mM for l-alanine and </=10 mM for l-valine, rates of gerP spore germination increased up to

221 nd transporters, CLC(F)s bear a channel-like valine rather than a transporter-like glutamate, and yet

222 reover, mutagenesis analyses revealed that a valine residue at position 264 in the rat p75 neurotroph

223 Only mutation of the H-helix valine residue V228 to leucine prevented phosphorylation

224 sine and the transfer of a methyl group to l-valine residue.

225 d inversion of the alpha-stereocenter at the valine residue.

226 ich negatively affect protease activity, and valine residues 785 and 787, which negatively affect deu

227 The leucine and valine residues insert into the binding groove while the

228 sion and processing, whereas substitution of valine residues resulted in hypofusogenic F proteins des

229 approximately 500 nM), by replacing the two valine residues with tert-leucine and the C-terminal pro

230 ic protein with an unusually high content of valine residues.

231 gauche(-) side-chain rotamer for one of the valine residues.

232 200, and 100 nM for isoleucine, leucine, and valine, respectively.

233 chemoirradiative procedure by showing that a valine-restricted diet is sufficient to empty the bone m

234 In mice fed a valine-restricted diet, HSC frequency fell dramatically

235 Furthermore, dietary valine restriction emptied the mouse bone marrow niche a

236 in HSC maintenance and suggest that dietary valine restriction may reduce iatrogenic complications i

237 ,(15)N]-alanine and [U-(13)C,(15)N]-N-acetyl-valine, revealed excellent performance for sequences wit

238 ransmembrane anchor or an artificial leucine-valine sequence yielded normal fusion activities.

239 e fusion machinery, or by artificial leucine-valine sequences.

240 In the valine series, the bulk of the substituent at the nitrog

241 inositol, phosphocholine, sylloinositol, and valine showed statistically significant different concen

242 The smaller valine side chain in PR(I50V) eliminated hydrophobic int

243 In G52V DAAO, the valine side chain occupies the site that in wild-type DA

244 molecule, whereas introduction of a bulkier valine side chain selectively blocked GTP binding by ste

245 al aspartate, of the C-terminal fragment, to valine stabilizes the fragment.

246 ike polymerases, with leucine, isoleucine or valine steric gates, in many taxa of the phylum Actinoba

247 A valine-substituted peptide (Vu-In(DeltaV); +ICDINGVCVDV-

248 novel mutations including a glutamic acid to valine substitution (E1338D), a glutamine to leucine sub

249 e APP gene that corresponds to an alanine to valine substitution at position 673 in APP (A673V), or p

250 peptide containing the amino acid alanine to valine substitution corresponding to position 117 of the

251 om delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase).

252 sine-to-phenylalanine (Y-F) and threonine-to-valine (T-V) capsid mutants, designed to avoid proteasom

253 nd guanosine) and kokumi (gamma-l-glutamyl-l-valine) taste-related molecules was ascertained both in

254 d chain amino acids (isoleucine, leucine and valine) that have been identified previously as potentia

255 Alanine, valine, threonine (often in N-alpha-acetylated form), an

256 n of many amino acids, including isoleucine, valine, threonine, and 4-aminobutanoate, which has been

257 the second antibody, the side chain of HCDR3 valine ties into site I like IL-6R Phe(279), whereas a L

258 ild-type hMD-2, a relatively minor change of valine to alanine at position 135 completely abolished t

259 occurs at valine 767 and that a switch from valine to alanine at this position prevented cleavage an

260 ther cancers, and a kinase activating single valine to glutamate substitution at residue 600 (BRAF(V6

261 he human ErbB2 protein), which can undergo a valine to glutamic acid (V(664)E) mutation at the center

262 PRNP sequencing demonstrated a valine to glycine mutation at codon 176, with valine hom

263 ution resulting in an amino acid change from valine to isoleucine at residue 19 of Nsp1beta diminishe

264 caused by a single substitution, a change of valine to methionine at position 429 (V429M), within the

265 The mutation resulted in a substitution of valine to methionine at residue 118 of the VEGF-D protei

266 beta3 subunits having gain-of-function V9'S (valine to serine at the 9'-position) mutations in transm

267 bic (in)activation and oxygen tolerance, the valine-to-histidine mutation has the most spectacular ef

268 Approximately 4% of black Americans carry a valine-to-isoleucine substitution (V122I) in the transth

269 rvival in the majority of U.S. subjects with valine-to-isoleucine substitution at position 122 (Val12

270 the effects of both valine-to-methionine and valine-to-leucine substitutions at this position in both

271 study, we characterized the effects of both valine-to-methionine and valine-to-leucine substitutions

272 NP) brain-derived neurotrophic factor (BDNF) valine-to-methionine substitution at codon 66 (Val66Met)

273 units harbored gain-of-function, leucine- or valine-to-serine mutations at 9' or 13' positions (L9'S

274 ubunits with mutant beta3 subunits harboring valine-to-serine mutations at 9'- or 13'-positions.

275 ance, including recruitment of mitochondrial valine transfer RNA (tRNA(Val)) to play an integral stru

276 ired for the initial separation of all seven valine tRNAs from three distinct polycistronic transcrip

277 ase in the levels of both type I and type II valine tRNAs.

278 s with future diabetes: isoleucine, leucine, valine, tyrosine and phenylalanine.

279 e circulating levels of isoleucine, leucine, valine, tyrosine, and phenylalanine, as well as single-n

280 A) signature, including isoleucine, leucine, valine, tyrosine, and phenylalanine, has been associated

281 ther the transgene encoded methionine (M) or valine (V) at polymorphic residue 129.

282 and single mutation analysis revealed that a valine (V) residue at position 190 in HA is responsible

283 Specifically, we demonstrate that two valine (V) residues and beta-strand propensity in QVKEVT

284 segments rich in proline (P), glutamate (E), valine (V), and lysine (K).

285 Subjects with the Methionine (Met)/Valine (Val) and Val/Val genotypes showed higher fractio

286 leads to a methionine (Met) substitution for valine (Val) at codon 66 (Val66Met) will affect stroke o

287 Here we report that a subtle leucine (Leu)-valine (Val) change at position 501 in the envelope glyc

288 acids (BCAAs) leucine, isoleucine (Ile), and valine (Val) in the mitochondria efficiently allows the

289 amine (Glx), serine (Ser), alanine (Ala) and valine (Val).

290 d GmRGS2 on GmGalpha1-4 result from a single valine versus alanine difference.

291 des with leucine (LRP), phenylalanine (FRP), valine (VRP), and alanine (ARP) residues at these positi

292 is a chiral amide base synthesized from (S)-valine was determined by single-crystal X-ray diffractio

293 Cbz-protected (S)-valine was first coupled to the amino group of (S)-m-tri

294 arkably, the specificity against non-cognate valine was not improved by the presence of tRNA in eithe

295 es from chlorination of lysine, tyrosine and valine were investigated.

296 sm was also not seen between the germinant L-valine, which acts via a GR, and the germinant dodecylam

297 Amino acids such as phenylalanine and valine, which are not known to respond to cellular swell

298 with the exception of the branched chain AA valine, which was elevated in diabetic animals (P < 0.05

299 edicts the replacement of a highly conserved valine with a glycine.

300 nts in the NCI-60 lung carcinoma cell lines, valine with high expression and isoleucine with low expr