1 ant disorder caused by mutations in p97/VCP (
valosin-containing protein).
2 Here, we report that p97, a
valosin-containing protein (
also called VCP), plays an e
3 Our data identify two molecules,
valosin-containing protein and apoptosis-linked gene-2 (
4 tudy, we show that interactions of Atx3 with
valosin-containing protein and hHR23B are dynamic and mo
5 membranes, a process known to be mediated by
valosin-containing protein and necessary for ER-associat
6 er functional convergence, ubiquilin 2, p62,
valosin-containing protein and optineurin are all linked
7 d by C1orf124 requires its interactions with
valosin-containing protein and PCNA.
8 ovel PTPN22 substrates (Vav, CD3epsilon, and
valosin containing protein)
and two known substrates of
9 The AAA-ATPase p97/
valosin-containing protein associates with both CaR and
10 h a variety of cellular activities) p97/VCP (
valosin-containing protein)
cause a dominantly inherited
11 ant disorder caused by mutations in the VCP (
valosin-containing protein)
gene.
12 roteome revealed that a 9-kDa protein, small
valosin-containing protein-
interacting protein (SVIP), i
13 The cytosolic p97/
valosin-containing protein is an essential ATPase for de
14 Valosin-containing protein is recruited to Insig-1 throu
15 ormally after PR39 treatment, and binding of
valosin-containing proteins is not impaired.
16 verse cellular activities), also called VCP (
valosin-containing protein),
is an important therapeutic
17 p97, also known as
valosin-containing protein,
is a versatile participant i
18 Valosin-containing protein-
like ATPase of Thermoplasma a
19 llowing receptor engagement, suggesting that
valosin-containing protein may target the ubiquitinated
20 to the Hrd1-mediated ubiquitination and the
valosin-containing protein-
mediated extraction pathway.
21 FTD with mutations in progranulin (n = 36),
valosin-containing protein (
n = 5), charged multivesicul
22 VCIP135 (
valosin-containing protein p97/p47 complex-interacting p
23 he members of this family, the hexameric p97/
valosin-containing protein p97/VCP, is essential for the
24 The 97-kDa
valosin-containing protein (
p97-VCP) belongs to the AAA
25 The 97-kDa
valosin-containing protein (
p97-VCP) plays a role in a w
26 NMR titration experiments confirmed a
valosin-containing protein/
p97 interaction motif and ide
27 Valosin-containing protein/
p97 is an ATP-driven protein
28 The AAA ATPase p97 (also called
valosin-containing protein)
participates in the retro-tr
29 tion of growth factor receptors and p97 VCP (
valosin-containing protein,
termed Cdc48 in Saccharomyce
30 usly identified putative molecular chaperon,
valosin-containing protein,
undergoes tyrosine phosphory
31 Valosin containing protein (
VCP) mutations also lead to
32 ER-associated degradation (ERAD), including
valosin-containing protein (
VCP) and Hrd1.
33 We identify here
valosin-containing protein (
VCP) as a novel substrate of
34 ns followed by proteomic analysis identified
valosin-containing protein (
VCP) as an Akt-binding prote
35 Our proteomic analysis identifies
valosin-containing protein (
VCP) as an mtHtt-binding pro
36 family member known to interact with the p97/
valosin-containing protein (
VCP) ATPase.
37 The 97 kDa
valosin-containing protein (
VCP) belongs to a highly con
38 The 97-kDa molecular chaperone
valosin-containing protein (
VCP) belongs to a highly con
39 Mutations in
valosin-containing protein (
VCP) cause a rare, autosomal
40 Missense mutations of
valosin-containing protein (
VCP) cause an autosomal domi
41 Mutations in
valosin-containing protein (
VCP) cause inclusion body my
42 Mutations in
valosin-containing protein (
VCP) cause inclusion body my
43 dentified a p.R191Q amino acid change in the
valosin-containing protein (
VCP) gene in an Italian fami
44 nerative disorder caused by mutations in the
valosin-containing protein (
VCP) gene.
45 nerative disorder caused by mutations in the
valosin-containing protein (
VCP) gene.
46 Valosin-containing protein (
VCP) is a highly expressed m
47 p97/
valosin-containing protein (
VCP) is a type II ATPase ass
48 Mutations in the gene encoding
valosin-containing protein (
VCP) lead to multisystem pro
49 Valosin-containing protein (
VCP) mutations cause inclusi
50 ical inhibition of either the AAA ATPase p97/
valosin-containing protein (
VCP) or the proteasome resul
51 the membrane by the p97 ATPase [also called
valosin-containing protein (
VCP) or, in yeast, Cdc48].
52 The
valosin-containing protein (
VCP) participates in signali
53 p97/
valosin-containing protein (
VCP) physically interacts wi
54 ciated with various cellular activities) p97/
valosin-containing protein (
VCP) subsequently dislodges
55 We observed that both WRNp and
valosin-containing protein (
VCP) were present in the nuc
56 Among the protein targets,
valosin-containing protein (
VCP), a homolog of the SNARE
57 Here, we show that mutation or inhibition of
Valosin-Containing Protein (
VCP), a ubiquitin-dependent
58 Here, we examined the function of
Valosin-containing protein (
VCP), a ubiquitin-selective
59 We identify
valosin-containing protein (
VCP), an AAA (ATPases associ
60 Here, we identify the ATPase p97/
valosin-containing protein (
VCP), an enzyme with segrega
61 and the ubiquitin-binding protein dislocase,
valosin-containing protein (
VCP), may act in concert dur
62 we discovered that EPSTI1 interacts with the
valosin-containing protein (
VCP), resulting in the degra
63 y or by depletion or pathogenic mutations in
valosin-containing protein (
VCP), the human ortholog of
64 p97/
valosin-containing protein (
VCP), which is involved in m
65 mitochondrial quality control (MQC) requires
valosin-containing protein (
VCP)-dependent Mitofusin/Mar
66 rings resembling the eukaryotic complex p97/
valosin-containing protein (
VCP).
67 defined reactions mediated by the AAA-ATPase
valosin-containing protein (
VCP)/p97 and augmented by th
68 sitional endoplasmic reticulum ATPase (TERA)/
valosin-containing protein (
VCP)/p97 directly binds to m
69 Presumably,
valosin-containing protein (
VCP)/p97 extracts misfolded
70 Valosin-containing protein (
VCP)/p97 is an AAA ATPase mo
71 We further show that
valosin-containing protein (
VCP)/p97 is involved in UV l
72 Binding to the AAA adenosine triphosphatase
valosin-containing protein (
VCP)/p97 is the only known b
73 Here, we report that
valosin-containing protein (
VCP)/p97 promotes the degrad
74 Here we demonstrate that
valosin-containing protein (
VCP)/p97 segregase functions
75 oteins in the media, such as mutant SOD1 and
valosin-containing protein (
VCP)/p97.
76 y in Wld(S) requires the N16-binding protein
valosin-containing protein (
VCP)/TER94.
77 six missense mutations in the gene encoding
valosin-containing protein (
VCP, a member of the AAA-ATP
78 Valosin-containing protein (
VCP/p97) ATPase (a.k.a. Cdc4
79 in- and proteasome-binding factors Rad23 and
valosin-containing protein (
VCP/p97), findings that supp
80 Valosin-containing protein (
VCP; p97; cdc48 in yeast) is
81 nerative disorder caused by mutations in the
valosin-containing protein (
VCP7) gene.
82 C1orf124 also binds to the AAA-ATPase
valosin-containing protein via its SHP domain, and cellu