ライフサイエンスコーパス: var

1 Each parasite possesses about 60 var genes, and switching between active var loci results

2 stages known as Pf EMP1 encoded by up to 60 var genes per genome.

3 n between the number of domains comprising a var gene and their sequence conservation.

4 of a domain cassette (DC) present in group A var genes from six genetically distinct P. falciparum pa

5 Transcript levels of group A var genes, including genes encoding domain cassette 13,

6 SIS) pathway in the C. neoformans serotype A var. grubii lineage, in which tandem transgene arrays tr

7 y molecular players in determining whether a var gene is active or silenced.

8 t 60 var genes, and switching between active var loci results in antigenic variation.

9 ntrons are associated with the single active var gene at the time in the cell cycle when the single v

10 eic acid molecules down-regulated the active var gene, erased the epigenetic memory, and induced expr

11 pression, PfMYST was recruited to the active var promoter.

12 increased the attractiveness of T. aestivum var.

13 All var genes are silenced or transcribed at low levels in b

14 sitica var. nicotianae, Alternaria alternata var. nicotianae and Rhizoctonia solani.

15 CR using a set of 42 primer pairs amplifying var subtype-specific loci covering most var/PfEMP1 subty

16 properties of IE collected on admission, and var gene transcription using quantitative polymerase cha

17 the presence of two hybrid classes, F1s and var. incana backcrosses, as would be expected on a relat

18 emate that had been coinoculated with wt and var viruses.

19 pertoire structure matters for the antigenic var diversity of the parasite population remaining after

20 ng kinetics and quality attributes of apple (var. Granny Smith) slices during drying.

21 60 degrees C and 2m/s, CD sample) on apple (var. Granny Smith) behavior during in vitro gastric dige

22 ated expression of both virulence-associated var genes and PfAP2-g, a transcription factor controllin

23 olate MUT4330 of Penicillium aurantiogriseum var. viridicatum which harbors six virus species, some h

24 uDGAT1, from the transcriptome of C. avigera var pulcherrima developing seeds.

25 ic class A LPAT2s and a cDNA from C. avigera var. pulcherrima (CpuLPATB) encoding a microsomal, seed-

26 ea viscosissima (CvLPAT2) and Cuphea avigera var. pulcherrima (CpuLPAT2a) encoding microsomal, seed-s

27 The dinoflagellate Pyrodinium bahamense var. compressum is one of the main species causing harmf

28 pers (Capsicum annuum), chards (Betavulgaris var. cicla), artichokes (Cynarascholymus)) and fruits (R

29 Strict pairing between var gene promoters and a second promoter within an intro

30 -exclusive transcriptional switching between var genes allows parasites to escape host antibodies.

31 arborescent forests (Cystoseira brachycarpa var. balearica) versus an alternate state: bushland (Dic

32 encoded by a large multi-gene family called var.

33 offea arabica (Arabica) and Coffea canephora var. robusta (Robusta) commercial stocks in each step of

34 15 different cultivars of chillies (Capsicum var.) grown in temperate climate Denmark and determined

35 The presence of H. capsulatum var. farciminosum DNA was confirmed by sequencing the cl

36 rts of the direct detection of H. capsulatum var. farciminosum in equine blood and at high frequency

37 s with suspected cases of EZL, H. capsulatum var. farciminosum was confirmed by extraction of DNA fro

38 existence of two subgroups of H. capsulatum var. farciminosum.

39 Histoplasma capsulatum var. farciminosum, the causative agent of epizootic lymp

40 oded by orf36 from Micromonospora carbonacea var. africana that mediates the flavin-dependent double

41 choke and cultivated cardoon (C. cardunculus var. altilis) parental genotypes and low-coverage (0.5 t

42 Globe artichoke (Cynara cardunculus var. scolymus) is an out-crossing, perennial, multi-use

43 ate time point, 9 subtelomeric and 8 central var genes were transcribed at the same levels in almost

44 ranscribed the same subtelomeric and central var genes, except for var2csa CONCLUSIONS: The duration

45 ral rearrangements focused in antigen-coding var genes.

46 berries, and cultivated and wild M. communis var. leucocarpa DC, characterized by white berries.

47 ples, namely cultivated and wild M. communis var. melanocarpa DC, characterized by red/purple berries

48 ted with severe disease outcome, we compared var transcript levels in parasites from 88 children with

49 of five disparate studies of Pinus contorta var.

50 d and healthy lodgepole pine (Pinus contorta var. latifolia) trees and ii.) from sites with and witho

51 le host tree [lodgepole pine (Pinus contorta var. latifolia)] was not directly affected by prefire ou

52 tein 1) family that bind EPCR, including DC8 var genes that have previously been linked to severe ped

53 lines expressing the two brain-adherent DC8-var genes did not bind to any of the known microvascular

54 to involve a general reduction in detectable var gene expression.

55 . vulgaris and in aerial parts of A. dioicus var. aethusifolius (H.Lev.) H.Hara [Syn.: Aruncus aethus

56 noids in different organs of Aruncus dioicus var. vulgaris and in aerial parts of A. dioicus var. aet

57 tence of "strains" characterized by distinct var gene repertoires.

58 ation, we also find evidence of multi-domain var structure and synteny in Plasmodium gaboni, one of t

59 MP-1 molecules and express the same dominant var transcript.

60 cond promoter within an intron found in each var gene is required for silencing and counting of var g

61 nts, found in the regulatory regions of each var gene, are bound by distinct nuclear protein complexe

62 levels of PfEMP1 domain cassette 8-encoding var genes.

63 analysis revealed that DC6- and DC8-encoding var transcripts in combination with high parasite biomas

64 bility in closely related species P. eryngii var.

65 w simple evolutionary mechanisms can explain var gene structuring on multiple levels and have importa

66 h sequence of the most prominently expressed var genes in three patients diagnosed with severe anemia

67 Despite extensive var DBLalpha diversity and minimal overlap between reper

68 ieties, Wisfal (Medicago sativa ssp. falcata var. sativa var. Chilean), with contrasting tolerance/se

69 pecific members of the Plasmodium falciparum var gene/PfEMP1 (P. falciparum erythrocyte membrane prot

70 g shoots of Aruncus dioicus (Walter) Fernald var. vulgaris (Maxim.) H.Hara (Rosaceae), collected from

71 and 23.4 min, 84.2 degrees C, and 63.8% for var. 'Touriga Nacional' (red variety).

72 ong noncoding RNAs (lncRNAs) initiating from var introns are associated with the single active var ge

73 veolens var. rapaceum), celery stalks (A. g. var. dulce) and leaf celery (A. g. var. secalinum).

74 ks (A. g. var. dulce) and leaf celery (A. g. var. secalinum).

75 Recombination clearly generates var diversity, but the nature and control of the genetic

76 lta(18) O series of Smith fir (Abies georgei var. smithii) on the southeastern Tibetan Plateau, and u

77 (Raphanus sativus), celery (Apium graveolens var. dulce), tomato (Lycopersicon lycopersicum), and sug

78 pis alba) and celery roots (Apium graveolens var. rapaceum), celery stalks (A. g. var. dulce) and lea

79 haracterize the gene complement in P. hallii var. filipes and enable gene expression analysis in this

80 Intradermal infections had higher var gene transcript levels than intravenous infections a

81 tigene families, including the hypervariable var genes, is broadly conserved, but P. falciparum has a

82 To identify var/PfEMP1 variants associated with severe disease outco

83 ent with the importance of H4 acetylation in var gene expression, PfMYST was recruited to the active

84 od for analyzing evolutionary constraints in var genes, and is also flexible enough to be easily appl

85 ts and genome-wide recombination hotspots in var genes, we show that during the parasite's sexual sta

86 onstrated a role for epigenetic processes in var regulation.

87 We show that switches in var gene expression do not appear to involve interaction

88 al positioning that occur during switches in var gene expression.

89 switching is mediated by clonal variation in var expression, and recent in vitro studies have demonst

90 telomeric highly variable genes and internal var genes, indicating mutations arising during self-mati

91 ular mass (LMM) extract of Cichorium intybus var. silvestre (red chicory) has been shown to inhibit v

92 cted from several types of Cichorium intybus var. silvestre salads ("Chioggia", "Treviso", "Treviso t

93 ble riparian forms on other Pacific Islands, var. newellii appears to represent parallel incipient ec

94 ges, ectopic recombination between isogenous var paralogs occurs near low folding free energy DNA 50-

95 extract of immature kumquat (Citrus japonica var. margarita) were identified and quantified (mg/100g

96 The octoploid (2n=88) Fallopia japonica var. japonica (Houtt.) Ronse Decraene is a single female

97 um-enriched pakchoi (Brassica chinensis Jusl var parachinensis (Bailey) Tsen & Lee).

98 f the blue honeysuckle (Lonicera caerulea L. var.

99 nt study, curly endive (Cichorium endivia L. var. crispum) and escarole (Cichorium endivia L. var. la

100 crispum) and escarole (Cichorium endivia L. var. latifolium) accessions were investigated for their

101 Belgian endive (Cichorium intybus L. var. foliosum Hegi), a popular produce in northern Europ

102 by inoculating adlay (Cois lachrymal-jobi L. var. ma-yuen Stapf) with Monascus purpureus may protect

103 oids found in broccoli (Brassica oleracea L. var. italica), carrot (Daucus carota), corn (Zea mays),

104 ee plants, viz. rapa L., Raphanus sativus L. var. and Eruca sativa Mill., were analyzed with this met

105 quantified in the pod of Raphanus sativus L. var. caudatus Alef extracts (2253.05+/-246.18 and 111.94

106 Herein, flowers of Bauhinia variegata L. var. candida alba Buch.-Ham were submitted to electron b

107 -quality ethanol/water for Vitis vinifera L. var. 'Viosinho' (white variety), and 23.4 min, 84.2 degr

108 Grapevine leaves (Vitis vinifera L. var. Malvasia Fina and Touriga Franca) under culinary tr

109 Spice peppers (Capsicum annuum L.) var. Lemeska and Lakosnicka paprika were investigated to

110 tracted from the resin of Pistacia lentiscus var. chia and comparatively investigated their effects o

111 ntial of polyphenols extracted from lettuce (var. Maravilla de Verano), in J774A.1 macrophages stimul

112 egulated genes were a subset of group A-like var genes (HB3var3, 3D7_PFD0020c, ITvar7, and ITvar19) t

113 itter melons (WBM; Momordica charantia Linn. var. abbreviata Ser.) on Propionibacterium acnes-induced

114 LA) pigmentation in M. cupreus and M. luteus var. variegatus occurred via separate yet strikingly sim

115 composed of S. lycopersicum, S. lycopersicum var cerasiforme, and Solanum pimpinellifolium to map loc

116 Pod corn (Zea mays var tunicata) was once regarded as ancestral to cultivat

117 interior Douglas-fir (Pseudotsuga menziesii var. glauca) from multiple populations were grown in mul

118 of coast Douglas-fir (Pseudotsuga menziesii var. menziesii) growing at three test sites with distinc

119 of coast Douglas-fir (Pseudotsuga menziesii var. menziesii) to test the hypotheses: (i) cool-tempera

120 types found in xeric (var. hallii) or mesic (var. filipes) habitats.

121 ying var subtype-specific loci covering most var/PfEMP1 subtypes.

122 dium falciparum is mediated by the multicopy var gene family.

123 by members of a multicopy gene family named var.

124 lecular types of serotype A or C. neoformans var. grubii (molecular types VNI, VNII, and VNB) and one

125 In diploid isolates of C. neoformans var. grubii (serotype AA) and of hybrids with C. neoform

126 While most isolates of C. neoformans var. grubii belong to one of three major lineages (VNI,

127 tely 95% spores) of serotype A C. neoformans var. grubii were fully virulent (100% lethal infection)

128 ients infected with strains of C. neoformans var. grubii with identical genotypes exhibited >/=4-fold

129 rotype AA) and of hybrids with C. neoformans var. neoformans (serotype AD) such aneuploidies have res

130 In contrast, the C. neoformans var. neoformans map was completely different.

131 Cryptococcus neoformans var. grubii is the causative agent of cryptococcal menin

132 ated by the modular genetic architectures of var genes that encode varying numbers of antigenic domai

133 tant characteristic in the classification of var genes.

134 ne is required for silencing and counting of var genes by the mechanism that controls mutually exclus

135 cture, significant for the high diversity of var genes that compose it at a local level, supports the

136 sequencing the conserved DBLalpha domain of var genes from six sentinel sites in Uganda we found tha

137 Deep sampling of the DBLalpha domain of var genes in the local population of Bakoumba, West Afri

138 uffy Binding Like-alpha (DBLalpha) domain of var genes.

139 lencing and mutually exclusive expression of var genes is regulated by the precise arrangement of ins

140 ined in detail the patterns of expression of var in a well-characterized sample of parasites from Ken

141 d in parasites by a highly diverse family of var genes.

142 Looking at the population genomics of var genes in cases of uncomplicated malaria, we set out

143 F2 population derived from an intercross of var. hallii and filipes.

144 Here, networks of var genes that recombine freely are expected to have a u

145 we investigated the transcription pattern of var genes by real-time polymerase chain reaction, the ex

146 nic variation depends on tight regulation of var gene expression, ensuring that only a single var gen

147 subset of coexisting dominant repertoires of var genes whose degree of antigenic overlap depends on t

148 hal of human malaria parasites, switching of var gene expression results in alternating expression of

149 to obtain bioactive compounds of B. oleracea var capitata showed to be a promising alternative to con

150 rd (Brassica nigra) and collard (B. oleracea var. acephala) and the effects of leaf nitrogen and gluc

151 e mutation in cauliflower (Brassica oleracea var botrytis) confers an abnormal pattern of anthocyanin

152 d bioactive compounds from Brassica oleracea var capitata using supercritical CO2 and evaluated the a

153 Diets rich in broccoli (Brassica oleracea var italica) have been associated with maintenance of ca

154 Broccoli (Brassica oleracea var. italica) is a vegetable that requires the applicati

155 Broccoli (Brassica oleracea var. italica) is associated with varied beneficial healt

156 rassicaceae (Eruca sativa, Brassica oleracea var. sabauda) were stored in air and under a modified at

157 Kale (Brassica oleracea var. sabellica) reveals a great diversity of flavonoids,

158 vels across the Laverania subgenus, based on var-like sequences from eight single-species and three m

159 entii followed by V. opulus P3 and V. opulus var. americanum possessed the highest antioxidant capaci

160 neral, the study demonstrated that V. opulus var. sargentii followed by V. opulus P3 and V. opulus va

161 V. opulus var. sargentii fruit juice was a remarkably stronger ant

162 catechin (the main antioxidants in V. opulus var. sargentii) contributed to 40% and 23% of the total

163 dy the effects of Citrus grandis (L.) Osbeck var. tomentosa hort. fruit extract on the energy metabol

164 e DNA elements that are required for pairing var promoters and introns and thus are essential for reg

165 We found that parasite var transcripts encoding endothelial protein C receptor

166 d resistance against Phytophthora parasitica var. nicotianae, Alternaria alternata var. nicotianae an

167 ss for the activation of a single particular var gene that involves AP2 transcription factors and lnc

168 The same PF3D7_1255200 var gene was activated in 4 different experimental infec

169 tetraploid Vigna species (V. reflexo-pilosa var. glabra) provides genomic evidence of a recent allop

170 ls of 'Hort16A' (Actinidia chinensis Planch. var chinensis) kiwifruit were examined and the changes i

171 A) that has previously been shown to promote var gene transcription during the intraerythrocytic cycl

172 he methanol extract of Centaurea pulcherrima var. pulcherrima showed the superior free radical scaven

173 The present assembly of V. radiata var. radiata will facilitate genome research and acceler

174 iso)4E allele in some TuMV-resistant B. rapa var. pekinensis lines.

175 isense lncRNAs play a key role in regulating var gene activation and mutually exclusive expression.

176 ar gene at a time, maintaining the remaining var genes in a transcriptionally silent state.

177 were stronger for the more range-restricted var. incana.

178 The single island-endemic form, riparian var. newellii, showed especially strong differentiation

179 tic pathway of Streptomyces roseochromogenes var. oscitans.

180 narum) callus, and indica rice (Oryza sativa var. indica) callus.

181 al (Medicago sativa ssp. falcata var. sativa var. Chilean), with contrasting tolerance/sensitivity to

182 rface-sterilized garlic bulb (Allium sativum var. Purple Stripe).

183 persicum), and sugar snap pea (Pisum sativum var. macrocarpon) from an industrially impacted biosolid

184 o cucumber taxa, and suggest that C. sativus var. hardwickii is the progenitor of cultivated cucumber

185 sativus var. sativus and the wild C. sativus var. hardwickii.

186 tanical varieties: the cultivated C. sativus var. sativus and the wild C. sativus var. hardwickii.

187 SDH(var+) cells showed stabilized and hyperactivated hypoxia

188 h 34/105 PTEN(mut+) (P < 0.001) or 27/47 SDH(var+) patients (P = 0.06).

189 Patient-derived SDH(var+) lymphoblastoid cells had elevated cellular reactiv

190 ide/nicotinamide adenine dinucleotide in SDH(var+) cells.

191 gative CS and CS-like (CSL) individuals (SDH(var+)).

192 tients (27/105, P = 0.002) or PTEN(mut+)/SDH(var+) carriers (6/22, P = 0.038).

193 ve oxygen species, highest in PTEN(mut+)/SDH(var+) cells, correlating with apoptosis resistance.

194 Of 22 PTEN(mut+)/SDH(var+) females, 17 had breast cancers compared with 34/10

195 EN(mut+)) CS/CSL individuals (PTEN(mut+)/SDH(var+)).

196 s of steady-state p53 in the majority of SDH(var+) cells.

197 Notably, individuals with SDH(var+) alone had the highest thyroid cancer prevalence (2

198 the domain architectures of fully sequenced var gene repertoires we reveal a significant, non-random

199 NAs in trans triggers activation of a silent var gene in a sequence- and dose-dependent manner.

200 GS parasites in this cluster express similar var genes, more than would be expected by chance in the

201 C. sinensis var. pubilimba (You 510) differed from the cultivars of

202 Three cultivars of C. sinensis var. sinensis, Fuyun 7, Qiancha 7 and Zijuan contained s

203 ) differed from the cultivars of C. sinensis var. sinensis, with higher levels of theobromine, (+)-ca

204 ) differed from the cultivars of C. sinensis var. sinensis, with higher levels of theobromine, (+)-ca

205 The effect of infection of Citrus sinensis (var. Navelina) fruits with Penicillium digitatum was stu

206 Individual parasites express only a single var gene at a time, maintaining the remaining var genes

207 gene expression, ensuring that only a single var gene is expressed at a time while the rest of the fa

208 After infection of mosquitoes, a single var gene is selected for expression in the oocyst, and t

209 t the time in the cell cycle when the single var upstream promoter is active.

210 to express exclusively only one of the sixty var genes that encode PfEMP1 is essential for disease pa

211 ny evidence of a selective sweep of specific var genes or clonal epidemic structure related to the in

212 species (Bengalese finches, Lonchura striata var. domestica) greatly reduced the magnitude of vocal l

213 dback in Bengalese finches (Lonchura striata var. domestica) to create sensory errors during vocal ge

214 Loss of Dek in Drosophila leads to a Su(var) phenotype and global reduction in heterochromatin.

215 SUVH1, a Su(var)3-9 homolog, was identified as a factor promoting th

216 a chimeric fusion protein consisting of a su(var)3-9, enhancer-of-zeste and trithorax (SET) histone m

217 in the absence of JIL-1 kinase activity, Su(var)3-7 gets redistributed and upregulated on the chromo

218 -suppressor effect of both Su(var)3-9 and Su(var)2-5 on position-effect variegation, providing eviden

219 s-of-function mutations for mod(mdg4) and Su(var)205 but not in similar experiments with JIL-1.

220 an ectopic site leads to Piwi, HP1a, and Su(var)3-9 recruitment to the site as well as H3K9me2/3 enr

221 expression levels of mod(mdg4) as well as Su(var)205; the latter gene codes for heterochromatin prote

222 lance the haplo-suppressor effect of both Su(var)3-9 and Su(var)2-5 on position-effect variegation, p

223 erochromatin protein 1a (HP1a; encoded by Su(var)205).

224 unphosphorylated STAT and HP1 [encoded by Su(var)205] in Drosophila and examined the effects on chrom

225 ffected, strongly indicating that ectopic Su(var)3-9 activity is not a direct cause of lethality.

226 Increasing expression of either Su(var)3-9 or Dicer-2 also led to an increase in life span.

227 uch as HP1, Trithorax-like (GAGA factor), Su(var)3-9, Brahma, MCM2, ORC2, and inner centromere protei

228 f dLsd1 and the histone methyltransferase Su(var)3-9 in promoting heterochromatin spreading at hetero

229 ecific histone H3 Lys-9 methyltransferase Su(var)3-9, the H1 C-terminal domain makes important contri

230 fic histone H3 lysine 9 methyltransferase Su(var)3-9.

231 position to the histone methyltransferase Su(var)3-9.

232 t the requirement for wild-type dosage of Su(var)205 and mod(mdg4) in enabling naturally occurring Y-

233 -7 functions as an effector downstream of Su(var)3-9 and H3K9 dimethylation in heterochromatic spread

234 omatin component, the zinc-finger protein Su(var)3-7.

235 SETD2 (Su(var), Enhancer of zeste, Trithorax-domain containing 2)

236 ucture, including overexpression of Sir2, Su(var)3-9, and Dicer-2, as well as decreased expression of

237 potent orthosteric inhibitors of specific Su(var)3-9, Enhancer-of-zeste, Trithorax (SET) domain methy

238 lays a key role in silencing by tethering Su(var)3-9 to heterochromatin.

239 the dose of the Su(var)3-7 gene and that Su(var)3-7 and JIL-1 loss-of-function mutations have an ant

240 an be rescued by reducing the dose of the Su(var)3-7 gene and that Su(var)3-7 and JIL-1 loss-of-funct

241 Reducing the dose of the Su(var)3-7 gene dramatically decreases this redistribution;

242 ti-silencing function for a member of the Su(var)3-9 family that has previously been associated with

243 function, as a Suppressor of Variegation [Su(var)] that is crucial to global heterochromatin integrit

244 These observations suggest a model where Su(var)3-7 functions as an effector downstream of Su(var)3-

245 H1 physically interacts with Su(var)3-9 and recruits it to chromatin in vitro, which pro

246 ion of embryonic ectoderm development or Su-(var)3-9; E(z); Trithorax (set)-7, encoding components of

247 a Polycomb repressive complex 2 (PRC2)--[Su-(var)3-9; E(z); Trithorax] (SET)-7, embryonic ectoderm de

248 es preferentially transcribed 8 subtelomeric var genes.

249 As such, var genes can be grouped into those that are short and d

250 rmed by simulation and a Populus szechuanica var.

251 rmed by simulation and a Populus szechuanica var. tibetica data set.

252 Here we use network analysis to show that var architecture and mosaicism are conserved at multiple

253 The var gene family of Plasmodium falciparum encodes the imm

254 The var gene transcript levels were determined in early and

255 The var genes of the human malaria parasite Plasmodium falci

256 ds earlier 'strain theory' by addressing the var gene family of Plasmodium falciparum.

257 e pattern, with a few exceptions such as the var genes involved in virulence and genes expressed at e

258 ion of clonal multigene families such as the var genes.

259 the multicopy multigene family known as the var genes.

260 Antigens encoded by the var gene family are major virulence factors of the human

261 ythrocyte membrane protein-1" encoded by the var multicopy gene family.

262 DBL1alpha domain primers to characterize the var genes expressed by CGS parasites after short-term in

263 he loss of PFB0080c markedly compromises the var gene switching process, leading to a marked reductio

264 ually exclusive expression of members of the var multi-gene family and appears to follow a non-random

265 iscovered in 2003, the identification of the var/PfEMP1 variants associated with severe malaria in ch

266 This study specifies the var/PfEMP1 types expressed in severe malaria in children

267 Although var2csa, the var gene encoding the PfEMP1 associated with placental m

268 These var genes encode P. falciparum erythrocyte membrane prot

269 Transcription of this var gene during parasite development in the mosquito cor

270 binding phenotype and the selection of three var genes, including two that encode the tandem domain c

271 Dioscorea japonica Thunb. var. pseudojaponica (DP) is consumed as food and widely

272 ction of 368 predominantly tomato and tomato var. cerasiforme accessions.

273 m tuberculosis (Mtb) or with M. tuberculosis var. bovis BCG (BCG).

274 ic elimination of Mycobacterium tuberculosis var. bovis BCG and found that Rab8b and its downstream i

275 ages of PsaA/B protein expression in the two var mutants.

276 ars 4,5,12:i:-, Typhimurium, and Typhimurium var. 5- were frequently not classified correctly, which

277 chitecture and sequence diversity underlying var-mediated host-parasite interactions evolved before t

278 ly diverse and that every child had a unique var DBLalpha repertoire.

279 It tracks the dynamics of all unique var repertoires in a population of hosts, and shows that

280 dditional elements results in an unregulated var gene.

281 oires are composed of both upsA and non-upsA var gene groups.

282 CGS parasites show upregulation of UpsA var genes and 2-cysteine-containing PfEMP-1 molecules an

283 is a major variant surface antigen, we used var Ups quantitative reverse transcription-PCR (qRT-PCR)

284 The patient first developed an R. variabilis var. regularior palate infection and later developed a c

285 ) virus (wt) and a silently mutated variant (var) thereof as parental virus strains.

286 sted significant between-country variations (var=0.19, p=0.002) and between-hospital variations (var=

287 9, p=0.002) and between-hospital variations (var=0.43, p<0.0001) in the individual risk of in-hospita

288 lted in a set of autotetraploid S. viminalis var. Energo genotypes (polyploid Energo [PP-E]; 2n = 4x

289 olite of the ascomycete Chloridium virescens var. chlamydosporum, was synthesized in 16 linear steps

290 of intrahost replication influences in vitro var gene transcript patterns.

291 ect of mosquito and host passage on in vitro var gene transcription was investigated.

292 itexin-2-O-xyloside (XVX) from Beta vulgaris var. (BVc) seeds, betaxanthin (R1) and betacyanin (R2) f

293 betacyanin (R2) fractions from Beta vulgaris var. (BVr) roots were combined and tested for cytotoxici

294 itexin-2-O-xyloside (XVX) from Beta vulgaris var. cicla L. (BVc) seeds, betaxanthin (R1) and betacyan

295 betacyanin (R2) fractions from Beta vulgaris var. rubra L. (BVr) roots were combined and tested for c

296 Kidney bean plants (Phaseolus vulgaris var. red hawk) grown in soil contaminated with 1000-2000

297 of the most common monovarietal white wine (var. Solaris) in Denmark.

298 on volcanically active Hawai'i Island, with var. glaberrima also extending to higher elevations and

299 tes, one infected with wt and the other with var virus.

300 includes two major ecotypes found in xeric (var. hallii) or mesic (var. filipes) habitats.