ライフサイエンスコーパス: variant CJD

1 oradic Creutzfeldt-Jakob disease (CJD) and 6 variant CJD brains.

2 Although variant CJD can be diagnosed during life by tonsil biops

3 disease, Creutzfeldt-Jakob disease (CJD) and variant CJD in humans.

4 regions in controls, sporadic CJD (sCJD) and variant CJD (vCJD) patients has identified three polymor

5 Since clinical variant CJD is uniformly associated with tonsillar prion

6 patients with neuropathologically confirmed variant CJD, but not from patients with other prion dise

7 e prion strain and are at risk of developing variant CJD.

8 a rendering plant and the risk of developing variant CJD.

9 Variant Creutzfeldt-Jakob disease (variant CJD) is difficult to distinguish from common psy

10 at causes variant Creutzfeldt-Jakob disease (variant CJD) is indistinguishable from the causative age

11 e appearance of a novel human prion disease, variant CJD, and the clear experimental evidence that it

12 ases between species, suggest that the early variant CJD cases may have been exposed during the precl

13 In 2002, 17 people died from variant CJD (vCJD) in the UK, compared with 20 in 2001 a

14 licated historically in kuru and recently in variant CJD.

15 ignated type 4t) different from that seen in variant CJD brain (type 4) or in brain from other CJD su

16 These data should inform attempts to model variant CJD epidemiology.

17 dementia, corticobasal degeneration and new variant CJD have been considered in affected individuals

18 iant of Creutzfeldt-Jakob disease (CJD), new variant CJD (nvCJD), was identified in the UK in 1996.

19 and ataxia, including suspected cases of new variant CJD.

20 n that may be especially relevant in the new variant CJD.

21 The arrival of variant CJD in the UK in the 1990s has intensified the s

22 dt-Jakob disease (CJD); there was no case of variant CJD.

23 One hypothesis is that cases of variant CJD have resulted from exposure to the BSE agent

24 gested that the observation of four cases of variant CJD living in an area with a population of 1.5 m

25 We identified cases of variant CJD through the National CJD Surveillance Unit,

26 Up to Aug 31, 1998, 26 cases of variant CJD with onset in the UK (Northern Ireland not i

27 We compared the observed number of cases of variant CJD within a particular distance of a rendering

28 The reported cluster of variant CJD cases in Kent is most probably a chance find

29 or is highly consistent with, a diagnosis of variant CJD and negative in all patients subsequently co

30 It is unclear if a large epidemic of variant CJD will occur in the years ahead.

31 The observed and expected numbers of variant CJD cases living within a specified distance of

32 On second and third passages of variant CJD prions in Tg(MHu2M) mice, multiple strains o

33 cular features of this case overlap those of variant CJD.

34 er bovine spongiform encephalopathy (BSE) or variant CJD prions, may develop the neuropathological an

35 poradic Creutzfeldt-Jakob disease (sCJD), or variant CJD (vCJD) brains.

36 tonsil biopsy sample was positive for PrPSc, variant CJD could be diagnosed, which obviates the need

37 We conducted GWAS of sporadic CJD (sCJD), variant CJD (vCJD), iatrogenic CJD, inherited prion dise

38 of prion disease emerged in the UK, termed "variant CJD", thought to be acquired by consumption of b

39 r results do not support the hypotheses that variant CJD is an emerging illness in Washington or that

40 Our results also show that variant CJD has a different pathogenesis to sporadic CJD

41 For experimental exposure of astrocytes to variant CJD (vCJD), the kinetics of prion replication oc

42 C and MM2T, and a low sensitivity limited to variant CJD, Gerstmann-Straussler-Scheinker syndrome and

43 re closely similar) but can be infected with variant CJD prions, a human prion strain resulting from

44 es of a macaque experimentally infected with variant CJD.

45 prion protein in the urine of patients with variant CJD (vCJD) using protein misfolding by cyclic am

46 There is no evidence that people with variant CJD tended to live closer than the population as