ライフサイエンスコーパス: variant Creutzfeldt-Jakob disease

1 us 1, hepatitis C virus, enterovirus 70, and variant Creutzfeldt-Jakob disease.

2 d from human beings affected by sporadic and variant Creutzfeldt-Jakob disease.

3 case of bovine spongiform encephalopathy and variant Creutzfeldt-Jakob disease.

4 of prion disease in humans were diagnosed as variant Creutzfeldt-Jakob disease.

5 s a source of human-to-human transmission of variant Creutzfeldt-Jakob disease.

6 m those observed in sporadic, iatrogenic and variant Creutzfeldt-Jakob disease.

7 e methionine homozygote to both sporadic and variant Creutzfeldt-Jakob disease.

8 ease) or can be acquired, as is the case for variant Creutzfeldt-Jakob disease.

9 tissues in a unique series of nine cases of variant Creutzfeldt-Jakob disease.

10 laria, severe acute respiratory syndrome, or variant Creutzfeldt-Jakob disease.

11 iform encephalopathy (BSE) prions causes new variant Creutzfeldt-Jakob disease.

12 al targets for therapy, for example, in 'new variant' Creutzfeldt-Jakob disease.

13 RNP MV genotype individual can propagate the variant Creutzfeldt-Jakob disease agent and that the inf

14 onsistently demonstrated transmission of the variant Creutzfeldt-Jakob disease agent.

15 the PrP(Sc) that accumulates in the brain in variant Creutzfeldt-Jakob disease also contains a minori

16 ined from human post-mortem samples, of both variant Creutzfeldt-Jakob disease and Alzheimer's diseas

17 e chronic human neurodegenerative conditions variant Creutzfeldt-Jakob disease and Alzheimer's diseas

18 sions from donors who subsequently developed variant Creutzfeldt-Jakob disease and an asymptomatic re

19 etectable only in the urine of patients with variant Creutzfeldt-Jakob disease and had the typical el

20 14 urine samples obtained from patients with variant Creutzfeldt-Jakob disease and in none of the 224

21 nce that either Creutzfeldt-Jakob disease or variant Creutzfeldt-Jakob disease are transmitted by tra

22 issible spongiform encephalopathies, such as variant Creutzfeldt-Jakob disease, are believed to resul

23 ly 10(5)-fold dilution of 10% (wt/vol) human variant Creutzfeldt-Jakob disease brain homogenate, with

24 phoreticular system is a defining feature of variant Creutzfeldt-Jakob disease, but that the biochemi

25 eview focuses on transfusion-transmission of variant Creutzfeldt-Jakob disease by red cell preparatio

26 covered by this review, the transmission of variant Creutzfeldt-Jakob disease by transfusion has bee

27 tion as a precaution against transmission of variant Creutzfeldt-Jakob disease by transfusion of dome

28 Recent evidence that variant Creutzfeldt-Jakob disease can be transmitted by

29 iod makes it difficult to predict future new variant Creutzfeldt-Jakob disease case numbers; further

30 terest, and findings were followed-up in six variant Creutzfeldt-Jakob disease cases with 9.4 T high-

31 infection parameters from a UK cohort of 171 variant Creutzfeldt-Jakob disease cases.

32 In an effort to prevent new variant Creutzfeldt-Jakob disease, certain "specified of

33 spongiform encephalopathy (BSE) to humans as variant Creutzfeldt-Jakob disease (CJD) has affected ove

34 Variant Creutzfeldt-Jakob disease (CJD) is thought to be

35 ine spongiform encephalopathy to people as a variant Creutzfeldt-Jakob disease (CJD), it becomes crit

36 sting itself as a novel human prion disease, variant Creutzfeldt-Jakob disease (CjD).

37 ) has been done aside from a small sample of variant Creutzfeldt-Jakob disease (CJD).

38 to be susceptible to prions from humans with variant Creutzfeldt-Jakob disease (CJD); on second passa

39 'New variant' Creutzfeldt-Jakob disease (CJD) has strain char

40 Urine samples obtained from patients with variant Creutzfeldt-Jakob disease contained minute quant

41 Back-calculation analysis of the variant Creutzfeldt-Jakob disease epidemic in the United

42 The recent emergence of variant Creutzfeldt-Jakob disease has led to major publi

43 The outbreak of new variant Creutzfeldt-Jakob disease has raised the specter

44 ll transfusion recipient, who did not die of variant Creutzfeldt-Jakob disease, has been identified w

45 Three cases of variant Creutzfeldt-Jakob disease have been identified f

46 all previous definite and probable cases of variant Creutzfeldt-Jakob disease have been methionine h

47 form encephalopathy to humans in the form of variant Creutzfeldt Jakob disease, have raised concerns

48 naturally occurring scrapie in sheep and of variant Creutzfeldt-Jakob disease in humans.

49 fection for three individuals diagnosed with variant Creutzfeldt-Jakob disease in the USA and Canada.

50 compared with other transmission studies in variant Creutzfeldt-Jakob disease, including those on th

51 ntial for significant numbers of subclinical variant Creutzfeldt-Jakob disease individuals in at leas

52 New variant Creutzfeldt-Jakob disease is a novel human prion

53 analysis of prion strains suggests that new variant Creutzfeldt-Jakob disease is caused by BSE expos

54 ditions of humans and animals, one of which (variant Creutzfeldt-Jakob disease) is known to be a zoon

55 A novel acquired human prion disease, variant Creutzfeldt-Jakob disease, is thought to result

56 tudy of PrP(Sc) from autopsy-proved cases of variant Creutzfeldt-Jakob disease (n = 59) and compare t

57 All tested cases of new variant Creutzfeldt-Jakob disease (nvCJD) have been homo

58 , 1998, 35 deaths had been attributed to new variant Creutzfeldt-Jakob disease (nvCJD) in the United

59 There was no evidence of any death from variant Creutzfeldt-Jakob disease or from conditions tha

60 Risk assessments for transmission of variant Creutzfeldt-Jakob disease predicted that leukocy

61 In variant Creutzfeldt-Jakob disease, prion replication is

62 Evidence suggests that variant Creutzfeldt-Jakob disease prions circulate in bo

63 polymorphic codon in humans associated with variant Creutzfeldt-Jakob disease, pulls the N terminus

64 s) in lymphoid tissues of patients with 'new variant' Creutzfeldt-Jakob disease, sheep with natural s

65 indicates a single PrP(Sc) molecular type in variant Creutzfeldt-Jakob disease (termed type 2B), pres

66 type 1 PrP(Sc) was found in all 21 cases of variant Creutzfeldt-Jakob disease tested, irrespective o

67 As of mid-2016, 231 cases of variant Creutzfeldt-Jakob disease-the human form of a pr

68 The results show PrP(Sc) in variant Creutzfeldt-Jakob disease to be remarkably stere

69 region examined, and was also present in the variant Creutzfeldt-Jakob disease tonsil.

70 s our current understanding of the risks of (variant) Creutzfeldt-Jakob disease transmission via dent

71 Variant Creutzfeldt-Jakob disease (variant CJD) is diffi

72 The agent that causes variant Creutzfeldt-Jakob disease (variant CJD) is indis

73 Variant Creutzfeldt-Jakob disease (vCJD) and bovine spon

74 causes the fatal neurodegenerative condition variant Creutzfeldt-Jakob disease (vCJD) and, based on r

75 Our study indicates a prototype blood-based variant Creutzfeldt-Jakob disease (vCJD) assay has suffi

76 ical instruments from, a deceased carrier of variant Creutzfeldt-Jakob disease (vCJD) can be followed

77 humans, as a result of the rising number of variant Creutzfeldt-Jakob disease (vCJD) cases.

78 Variant Creutzfeldt-Jakob disease (vCJD) differs from ot

79 Variant Creutzfeldt-Jakob disease (vCJD) has a pathogene

80 Variant Creutzfeldt-Jakob disease (vCJD) has been recogn

81 Person-to-person transmission of variant Creutzfeldt-Jakob disease (vCJD) has occurred th

82 Infections with variant Creutzfeldt-Jakob disease (vCJD) have almost exc

83 A small number of patients with variant Creutzfeldt-Jakob disease (vCJD) have been treat

84 We report a case of preclinical variant Creutzfeldt-Jakob disease (vCJD) in a patient wh

85 rion disease reputed to be zoonotic, causing variant Creutzfeldt-Jakob disease (vCJD) in humans and h

86 ings are relevant to the current outbreak of variant Creutzfeldt-Jakob disease (vCJD) in the United K

87 The development of variant Creutzfeldt-Jakob disease (vCJD) in three recipi

88 sheep for relative human exposure levels and variant Creutzfeldt-Jakob disease (vCJD) incidence.

89 Variant Creutzfeldt-Jakob disease (vCJD) is a fatal neur

90 Variant Creutzfeldt-Jakob disease (vCJD) is a fatal neur

91 Variant Creutzfeldt-Jakob disease (vCJD) is a novel huma

92 Variant Creutzfeldt-Jakob disease (vCJD) is a unique and

93 sceptibility to, and clinical expression of, variant Creutzfeldt-Jakob disease (vCJD) is essential fo

94 Concerns have been raised that variant Creutzfeldt-Jakob disease (vCJD) might be transm

95 eographical variation in the distribution of variant Creutzfeldt-Jakob disease (vCJD) might indicate

96 ortex samples, from prion-affected patients (variant Creutzfeldt-Jakob disease (vCJD) n = 20, iatroge

97 f bovine spongiform encephalopathy (BSE) and variant Creutzfeldt-Jakob disease (vCJD) prions are fait

98 The transmission of variant Creutzfeldt-Jakob disease (vCJD) through blood t

99 appear to be a reservoir for transmission of variant Creutzfeldt-Jakob disease (vCJD) to humans.

100 e an increasing concern since the reports of variant Creutzfeldt-Jakob disease (vCJD) transmission th

101 Interindividual variant Creutzfeldt-Jakob disease (vCJD) transmission th

102 Estimates for the risk of transmitting variant Creutzfeldt-Jakob disease (vCJD) via blood trans

103 Identification of possible transmission of variant Creutzfeldt-Jakob disease (vCJD) via blood trans

104 Variant Creutzfeldt-Jakob disease (vCJD) was first descr

105 Variant Creutzfeldt-Jakob Disease (vCJD) was first repor

106 Variant Creutzfeldt-Jakob disease (vCJD), a novel form o

107 The onset of variant Creutzfeldt-Jakob disease (vCJD), and the unknow

108 cephalopathy (BSE) and its human equivalent, variant Creutzfeldt-Jakob disease (vCJD), are caused by

109 sfusion has been described in cases of human variant Creutzfeldt-Jakob disease (vCJD), experimental o

110 is C, bovine spongiform encephalopathy (BSE)/variant Creutzfeldt-Jakob disease (vCJD), Nipah virus, s

111 centers in lymphoid tissues of patients with variant Creutzfeldt-Jakob disease (vCJD), sheep with nat

112 veys to detect clinically silent carriers of variant Creutzfeldt-Jakob disease (vCJD).

113 an accurate non-invasive diagnostic test for variant Creutzfeldt-Jakob disease (vCJD).

114 phalopathy (BSE) prions, the causal agent of variant Creutzfeldt-Jakob disease (vCJD).

115 e neuropsychological profile associated with variant Creutzfeldt-Jakob disease (vCJD).

116 We report a case of variant Creutzfeldt-Jakob disease(vCJD) in a 74-year old

117 Transmission of variant Creutzfeldt-Jakob disease was observed from the

118 ce between PrP(Sc) types was maintained when variant Creutzfeldt-Jakob disease was transmitted to wil

119 an be detected in the urine of patients with variant Creutzfeldt-Jakob disease, we used the protein m