ライフサイエンスコーパス: variation

1 of oppositely charged residues shows minimal variation.

2 tle behaviour, despite selection on standing variation.

3 of P. falciparum, making them prone to high variation.

4 of circRNAs and further modulate phenotypic variation.

5 nd wild species, we characterize genome-wide variation.

6 ly effectiveness was associated with genetic variation.

7 substantial inter-individual natural genetic variation.

8 eusing them repeatedly from standing genetic variation.

9 this phenotype attributable to viral genetic variation.

10 ptures around three-quarters of the observed variation.

11 ased heritability arises from common genetic variation.

12 d on the presence of exogenous environmental variation.

13 or a disproportionate amount of interspecies variation.

14 ished studies and incorporated patient-level variation.

15 rrelation coefficient and the coefficient of variation.

16 ' resulting from phylogeny and environmental variation.

17 Many common diseases show wide phenotypic variation.

18 etween hind and forelimbs shows considerable variation.

19 display large population datasets of genetic variation.

20 chloroplast microsatellite loci revealed no variation.

21 methods that implicitly account for spatial variation.

22 in had a very heterogeneous distribution and variation.

23 tant geological, climatic, and environmental variations.

24 conditional on proinflammatory IL-1 genetic variations.

25 ns to modulate transcriptomic and phenotypic variations.

26 e ocean and can manifest as global sea level variations.

27 of them) provide efficient buffering of size variations.

28 dence interval [CI], 17%-19%), with regional variation (11%-35%), and lower prevalence in Southern As

29 SRS is the major predictor of transcriptomic variation; a small number of genes (n = 263) were differ

30 We estimated that pneumococcal genomic variation accounted for 63% of the phenotype variation,

31 explaining the observed patterns of genetic variation across the xeric Caatinga biome.

32 cancer is typically associated with somatic variations, advances in DNA sequencing indicate that cel

33 ental validation to demonstrate that genetic variation affects expression of VAC14, a phosphoinositid

34 n pulse pressure variation and stroke volume variation after increasing tidal volume from 6 to 8 mL/k

35 timodel assessment was conducted to quantify variation among models and evaluate responses to climate

36 an be investigated using patterns of genetic variation among the people who lived in those times.

37 Little variation among watersheds in potential spawning habitat

38 Gene set variation analysis revealed that CD40L-responsive genes

39 ng intraclass correlation and coefficient of variation analysis.

40 tion, the relationship between environmental variation and abundance varied significantly among gradi

41 HPA axis genetic variation and activity were important predictors of cogn

42 Our results suggest that the variation and complexity of climate-driven variables cou

43 The connection between genetic variation and drug response has long been explored to fa

44 Little is known about how genetic variation and epigenetic marks interact to shape differe

45 The manner in which patterns of variation and interactions among demographic rates contr

46 generalizable due to cohort bias, biological variation and limited sample size.

47 The absolute change in pulse pressure variation and stroke volume variation after increasing t

48 rategy that allows for systematic structural variation and the ability to conduct a careful structure

49 e near-surface changes such as water content variations and permafrost alteration.

50 interfaces, 19% arise from family structural variation, and 27% are in repeat proteins likely reflect

51 ly improved repeatability, normal population variation, and correlation with VF and GCC thickness.

52 any loci of small effect underlie phenotypic variation, and identify five genomic regions associated

53 pounds, quantitative proteomics, copy number variation, and polysomal transcriptomics.

54 ational signatures, long-range mutation rate variation, and position-specific impact measures.

55 ation produced by mutation, standing genetic variation, and the rate of evolution over the last 40 mi

56 present a tiny minority of all known genetic variation, and therefore there is necessarily an imbalan

57 ntal variation on both selection and genetic variation are especially scarce.

58 underestimation, if statistics of the volume variation are well characterized.

59 s whose altered expression levels or allelic variations are associated with decreased bone mass and o

60 Anatomical variations are not diseases on their own and may be pres

61 explained only approximately 50% of genetic variation at 17 years.

62 bidopsis (Arabidopsis thaliana), and allelic variation at many loci contribute to this trait.

63 assays demonstrated that the minor T allele variation at rs604723 increased the activity of this fra

64 ring genome-wide patterns of methylation and variation at the DNA level in hatchery-reared coho salmo

65 aimed to quantify and understand prevalence variation at the global and regional levels.

66 studies have revealed an association between variation at the SLC4A7 locus and blood pressure.

67 is revealed significant associations between variation at the WNT16 and RSPO3 loci and fracture risk

68 g evidence that the T2D risk associated with variation at this locus is mediated through reduction in

69 fficient to assess the proportion of outcome variation because of provider practice.

70 an interesting model for examining body-size variation because of the high degree of worker polymorph

71 t of the genome, and have led to its genetic variation becoming a key part of studies of human evolut

72 3D surface morphometrics to quantify subtle variation between individuals.

73 in expression levels and propagation of this variation between molecules across cells.

74 Studying variation between places and services could be key to id

75 taxonomic differences in patterns of genomic variation between the mafic Piccard and ultramafic Von D

76 99.0% of the variation between the spectra were described by the firs

77 explains most of the shared nuclear genomic variation between these two species and demonstrates the

78 Variation between this and a conventional LC-MS/MS metho

79 The results reveal large variations between crop type and field sites.

80 terval [CI], .6%-42%); there was evidence of variation by season (P = .12).

81 r regression, evidence suggests that genetic variation can impact the entire distribution of the expr

82 y shows that the future temporal and spatial variation characteristics of precipitation are different

83 s are limited by low accuracy of copy-number variation (CNV) detection and low amplification fidelity

84 Recently copy number variation (CNV) has gained considerable interest as a ty

85 birds shows remarkably little interspecific variation compared with other taxa.

86 e detected with less than 10% coefficient of variation (CV) across a range from nearly 27.4 fM to 1.7

87 ylation, noncoding microRNA, and copy number variation data available from the Gene Expression Omnibu

88 ons in the maize genome and dramatic genomic variation driven by transposons, we hypothesize that tra

89 g crumb moisture content with no significant variations during shelf-life.

90 tella copri) or continuous microbial genetic variations (e.g., for Faecalibacterium prausnitzii) were

91 e much larger set of non-deleterious genomic variation, especially in non-coding regulatory regions o

92 To date, the fiscal consequence of hospital variation for autologous free flap breast reconstruction

93 alleles that provide beneficial quantitative variation for breeding.

94 Additionally, comparing general patterns of variation for the antennal transcriptional profiles in t

95 -3.60) to 3.85% (2.37-5.33), with no unusual variation from the adjusted national incidence of 3.13%

96 nd thymidine for S. pneumoniae For all other variations, gepotidacin MIC and disk results were consid

97 g, but inherent nonlinearities and parameter variation have, to date, required an approximate, numeri

98 odel aspects including climatic and temporal variations, how ENMs may be released into the environmen

99 However, the extent and types of genetic variation impacting embryonic gene expression, and their

100 at polymorphism rs11185644 may contribute to variation in 25(OH)D dose-response in healthy postmenopa

101 We observed variation in 40 of 41 genes comprising the NOD signaling

102 ed and replicated genome-wide protein coding variation in a total of 8,227 individuals with T2D and 1

103 in the CYP2R1 and GC gene may contribute to variation in baseline serum 25(OH)D concentration, and t

104 We investigated whether variation in binding of a transcription factor, the vita

105 We expressed asynchrony as the annual variation in bird phenology relative to spring phenology

106 , we explored the causes and consequences of variation in body mass of wild female Svalbard reindeer

107 st comprehensive characterisation of genetic variation in bovine beta-defensin genes and functional a

108 ults demonstrate a critical role for genetic variation in ChrY in regulating susceptibility to infect

109 s, and especially larger degrees of seasonal variation in climate, call for individuals and groups to

110 in spatial precision account for much of the variation in crowding, including the correlation between

111 d understanding of the magnitude and spatial variation in deadwood is vital for the development of re

112 wever, factors responsible for intraspecific variation in disease resistance remain unclear.

113 change in seed size are both associated with variation in diversification rates.

114 Variation in DNA methylation, an epigenetic mechanism, i

115 fects of ethnicity on D2R were not driven by variation in dopaminergic candidate genes.

116 Identifying individual genetic variation in drug metabolism pathways is of importance n

117 rtional increase in breakdown rates, despite variation in Ea values for these regions (0.75 +/- 0.13

118 ulatory assessments that account for spatial variation in emissions impacts.

119 We also evaluate the impact of variation in equipment setup on the accuracy of acquired

120 amples is revealing substantial cell-to-cell variation in expression levels and propagation of this v

121 ed within LRCs are highly insulated from the variation in expression of upstream genes, and thus LRCs

122 ith Polycomb marks have greater cell-to-cell variation in expression.

123 onal incidence of 3.13% (2.85-3.42), despite variation in feeding practices.

124 This variant alone explained 14% of the variation in fetuin-A levels.

125 We demonstrate that variation in Fgf8 expression has a nonlinear relationshi

126 Ppd-H1-dependent variation in flowering time under different ambient temp

127 Our results indicate that variation in folate level is governed by a more complex

128 Despite the significant variation in folate levels among tomato accessions, litt

129 nal air and on skin accounted for 54% of the variation in fold changes of urinary PAH metabolites (p

130 sleep abnormalities are common; for example, variation in genes involved in synaptic homoeostasis are

131 processes shaping spatiotemporal patterns of variation in genetic, morphological, and cultural traits

132 utans and 2 gibbons and observed undescribed variation in great apes.

133 technique which extracts dominant sources of variation in high dimensional datasets and produces thei

134 ity, were critical for generating fine-scale variation in homozygosity.

135 Limitations: The model did not control for variation in implementation of the laws.

136 ulation, we uncovered significant regulatory variation in individual yeast cells, both before and aft

137 Accordingly, variation in initial conditions may explain divergent po

138 genetic strategy revealed the broad natural variation in low-water-potential-induced ABA accumulatio

139 Technical variation in metagenomic analysis must be minimized to c

140 s provide no support for the hypothesis that variation in microbial community affects performance in

141 pecting the genomic partitioning of sequence variation in modern elite germplasm, highlighting region

142 to IAV segregates independent of copy number variation in multicopy ChrY gene families that influence

143 that sex-biases in infection are related to variation in multilayer contact networks structured by s

144 Furthermore, there is considerable variation in multiple aspects of screening and managemen

145 n this self-contained description of genomic variation in Next Generation Sequencing (NGS) results.

146 I found significant variation in niche position, niche breadth and interspec

147 Our work provides a general explanation for variation in observed diversity-ecosystem variability re

148 Comparatively high variation in OC storage between riverine and nonriverine

149 ng the forces that shape the great amount of variation in plant longevity, reproductive output and gr

150 among eukaryotes, and highlights unexpected variation in plastid genome architecture.

151 small total population size, but not spatial variation in population density, were critical for gener

152 eted of CD8(+) lymphocytes exhibited greater variation in population dynamics among tissues and cell

153 We have analyzed Y-chromosomal variation in populations from Transoxiana, a historical

154 effects is characterizing the spatiotemporal variation in predation risk.

155 hysical and evolutionary rationale for broad variation in protein family sizes, prevalence of compact

156 lcium dynamics of VSMC and to understand how variation in protein levels that arise due to diabetes c

157 rent types of stress indicating that natural variation in repeat numbers may optimize the chance for

158 Age-related variation in reproductive performance is ubiquitous in w

159 global weather data, which creates exogenous variation in running among friends, with data on the net

160 ective chemotaxis is limited by cell-to-cell variation in signaling.

161 Within-species variation in social structure has attracted interest rec

162 es the most comprehensive analysis so far of variation in specific EBV genes relevant to these diseas

163 ticular, we found that partially independent variation in stomatal and mesophyll conductance may allo

164 Moreover, the variation in tagged-ZnT8 expression and surface labeling

165 The model calculations remained robust to variation in test cost, prevalence of HSV infection, and

166 ere dynamics may help us quantify individual variation in the costs experienced from social and ecolo

167 esource footprints accounted for >90% of the variation in the damage footprints.

168 his model shows that the trend is due to the variation in the effective cross-sectional diameter of D

169 in morphology, we found an unexpectedly high variation in the expression patterns of neuropeptides ac

170 Here, we analyzed the genetic variation in the FOXP2 coding sequence in 63 chimpanzees

171 Our study suggests that nonsynonymous variation in the gene NKPD1 affects depressive symptoms

172 We conclude that although genetic variation in the HLA region is important to the aetiolog

173 tural predation gradient we demonstrate that variation in the identity of top predator species is ass

174 ological variation was related to population variation in the key female antagonistic trait (spine le

175 There was a wide variation in the number of opioid pills prescribed to pa

176 noes in subduction zones indicates along-arc variation in the physical condition of the underlying ma

177 Here we show that a significant variation in the rate of microearthquakes in the intrapl

178 dentified Tnni3k as one gene that influences variation in this composition and demonstrated that Tnni

179 t-point viral load, which is the fraction of variation in this phenotype attributable to viral geneti

180 been extensively, recorded their impacts on variation in tolerance are virtually unexplored.

181 We observed significant variation in trauma center mortality across Canadian pro

182 In explaining variation in violent aggression across populations, the

183 nnual cycle and understanding the effects of variation in weather and climate on productivity, recrui

184 We also examined annual variation in weather conditions, which are well recogniz

185 of Islands ophiolite, and we document large variations in (41)K/(39)K, covarying with previous deter

186 lution record reveals large orbitally driven variations in atmospheric CO2 concentration between [For

187 Variations in attrition may be explained by program dire

188 Our study limitations are the country-level variations in both surveillance methods and testing poli

189 Considering variations in chlorophyll a:b ratio with leaf age and ph

190 S/MS platform was implemented for monitoring variations in CHO cell culture media upon exposure to hi

191 cuticular drusen distribution; age-dependent variations in cuticular drusen phenotypes, including the

192 However, variations in degree of overlap were noted when data wer

193 irmed and expanded observations in mice that variations in dietary Na(+) intake do not alter the glom

194 VE AND To determine the relationship between variations in DNA methylation at birth and the developme

195 Previously, we observed that genetic variations in ECM genes are associated with an increased

196 Metabonomic studies implicated variations in gut microbial activities that mapped onto

197 ppear to largely explain previously observed variations in hairpin ribozyme stability.

198 antification of error estimations and output variations in image segmentation pipelines.

199 diseases, focusing on methods to account for variations in lung components and the interpretation of

200 ted this computational platform by detecting variations in mechanical output induced by drugs and in

201 For the first time, variations in miscanthus cell wall glycan components wer

202 ng the photosynthetic capacity of TMFs, with variations in N allocation and Rubisco activation state

203 Given the lessons learned regarding variations in nanomedicine delivery to different tumor t

204 the influence of the beam configurations and variations in peak dose and irradiated area in the respo

205 Here, we analysed natural variations in PfHRP2 and PfHRP3 sequences from Indian is

206 y of the cortical regions most responsive to variations in pitch or timbre at the univariate level of

207 ellar organization that accompany interwoven variations in sex, sex chromosome complement, and brain

208 imaging (fMRI) to explore whether trait-like variations in sleep patterns, measured in advance in bot

209 chical regression analyses further show that variations in spatial precision account for much of the

210 he findings are generally inconsistent, with variations in study designs and methods across populatio

211 A Center for Tsunami Research and we observe variations in TEC that correlate in time and space with

212 butions to noise by determining cell-to-cell variations in the abundance of mRNA and reporter protein

213 ntle convection, are likely to cause lateral variations in the back-arc mantle temperature.

214 BACKGROUD: Variations in the expression of the Netrin-1 guidance cu

215 -2 is critical for this interaction, whereas variations in the lock were tolerated.

216 Here, we show that variations in the mathematical functions currently used

217 s, intra-individual, and intra-gametogenesis variations in the meiotic program, A. rhodensis is an id

218 We found that small structural variations in the monomers dramatically affected the cry

219 As such, variations in the sulfur isotopic composition (delta(34)

220 In conclusion, variations in the topographic organization and magnitude

221 ext-generation sequencing to compare genomic variations in these lines.

222 gns to match the electrical performance with variations in wind speed.

223 We show that larger phenotypic variation increases connectivity among predators and the

224 demographic inferences and highlight genetic variation indicative of selection at specific genes.

225 specifically, how demographic and ecological variation influence social structure.

226 logical studies to quickly elucidate genetic variation involved in the etiology of complex traits.

227 Hence, mtDNA haplogroup variation is an important risk factor for ASD.

228 The mode of rainbelt variation is regionally variable, depending on surface t

229 st organismal traits and their intraspecific variation is unknown.

230 ormation on current impacts of environmental variation is widely lacking for many habitats and commun

231 and the concomitant ability to detect signal variation, is associated with a lengthening of incoming

232 We investigated whether hydraulic traits variation linked with climate and the diversification of

233 Here we report an apple genome variation map generated through genome sequencing of 117

234 ern cultivars, and construct a comprehensive variation map to provide genomic insights into the diver

235 ding experiments demonstrate that the output variation may be stabilized by an external source and es

236 actions vary across the striatum, involving variations not only in dopamine release but also in dopa

237 umor SUV has a within-subject coefficient of variation of approximately 10%.

238 ge RMSD of 2.93 A) and the sequence-specific variation of free energy is in excellent agreement with

239 To measure spatial variation of mechanical properties, one must determine t

240 in the IR was not sufficient to explain the variation of nucleotide substitution rates.

241 extensive nucleotide diversity, copy number variation of paralogous genes, and long repetitive seque

242 We also present a variation of Structure-seq2 in which a biotinylated nucl

243 A major factor in the variation of SUMO-target function is the balance between

244 This resulted in a predictable variation of the address-directed flux of a redox analyt

245 This has been attributed to a variation of the apparent built-in voltage of the PZT-LS

246 iastereoinduction and allowed for systematic variation of the catalyst to enhance selectivity.

247 serve a higher intolerance to normal genetic variation of the identified genes compared to known gene

248 While the variation of the side chains does not alter the photocon

249 Copy number variation of the target loci may be another explanation

250 Extreme variations of Earth's magnetic field occurred in the Lev

251 We also illustrate spatiotemporal variations of MEFs and explore implications for energy s

252 The global distribution and large variations of morphology of ultralow velocity zones vali

253 sulphate (SDS) micelles on pH-induced colour variations of phycocyanin was examined.

254 n by increased light gaps caused by seasonal variations of the canopy.

255 ing the simultaneous impact of environmental variation on both selection and genetic variation are es

256 her the same river properties that structure variation on recent timescales will also leave similar g

257 over, we show a widespread effect of genetic variation on the regulation of transcription, isoform us

258 Small variations on geometry and atomic charge were detected o

259 Surprisingly, loss of babA by phase variation or gene conversion is not dependent on the cap

260 is aberrant methylation results from genetic variation or non-genetic mechanisms, we generated human

261 37.3 nmol/L)] and showed significant monthly variation (P < 0.0001) with the highest values in July a

262 n has a nonlinear relationship to phenotypic variation, predicting levels of robustness among genotyp

263 By using these intensity variations, principal component and discriminant analysi

264 ctedly strong positive relationships between variation produced by mutation, standing genetic variati

265 lenging interpretation of individual genetic variations requires an accurate phenotypic description a

266 r model organisms to investigate how natural variation shapes traits, especially through the use of g

267 Genetic variation shared between closely related species may be

268 Ps) known to be involved in human eye colour variation showed stronger associations with our approach

269 ision data, based on within and between days variations, suggested an overall relative standard devia

270 ent SVScore, a tool for in silico structural variation (SV) impact prediction.

271 Structural variation (SV) influences genome organization and contri

272 Large structural variations (SVs) within genomes are more challenging to

273 magnetization and polarization show opposite variation tendencies against the doping level, and the s

274 , have allowed the identification of genetic variation that does not cause disease, but substantially

275 erable interest as a type of genomic/genetic variation that plays an important role in disease suscep

276 AMY1 and AMY2 show copy number variations that affect differences in amylase amount and

277 Here, we report technical variations that allow the improved detection of IL-4, IL

278 ith AF, but the contributions of genome-wide variation to AF susceptibility have not been quantified.

279 pt to address each of these contributions of variation to reduce noise.

280 ost, prevalence of HSV infection, and random variation to study assumptions.

281 The genetic variation underlying many heritable forms of cardiovascu

282 first in-depth survey of heart transcriptome variation using RNA-sequencing in 97 patients with dilat

283 Temporal variation was assessed by repeated measurements over hou

284 Variation was limited to children with 2 FLG LOF alleles

285 The variation was not random: models that overestimated at o

286 Ecological variation was related to population variation in the key

287 crease in DOPAC/DA ratio but interindividual variation was significantly reduced.

288 of agreement, within-subject coefficient of variation (wCV), and repeatability coefficient (r) were

289 ved in terms of leaf metabolic fluxes, these variations were not tightly linked to the genome structu

290 variation accounted for 63% of the phenotype variation, whereas the host traits considered here (age

291 We retained three components (50% of total variation) which, after rotation, were identified as thr

292 for further analysis of Cd and Zn tolerance variation, which is evident at different plant ages in v

293 y with strong tolerances to input faults and variations, which shows the feasibility of using them in

294 To identify common or rare genetic variation with potential therapeutic implications for T2

295 ral times to systematically correlate output variations with parameter changes or to tune parameters.

296 es from Indian isolates and correlated these variations with RDT reactivity.

297 , parent material types, and spatial climate variations, with significantly increased C:P and N:P rat

298 ghlight the non-linear response to sea-level variations, with the potential to amplify or mitigate ag

299 uality would increase with latitude (despite variation within regions) and traits would be correlated

300 yman Rise to investigate patterns of genomic variation within subseafloor populations.