ライフサイエンスコーパス: vascular endothelial growth factor A

1 ranscriptional upregulation and secretion of vascular endothelial growth factor A.

2 important for tumor angiogenesis induced by vascular endothelial growth factor A.

3 wo layers of collagen and in the presence of vascular endothelial growth factor-A.

4 egion via upregulation of the ER target gene vascular endothelial growth factor-a.

5 ia as efficiently as a 21-nt siRNA targeting vascular endothelial growth factor-A.

6 a similar proportion was observed to secrete vascular endothelial growth factor-A.

7 is with comparable magnitude as observed for vascular endothelial growth factor-A.

8 athway, activating HIF-target genes, notably vascular endothelial growth factor-A.

9 mpanied by increased plasma concentration of vascular endothelial growth factor-A.

10 f a novel alginate-based delivery system for vascular endothelial growth factor-A(165) (VEGF) that ex

11 wound beds, fibroblasts are rich sources of vascular endothelial growth factor A, a cytokine necessa

12 h factor AA and BB; placental growth factor; vascular endothelial growth factor A and D; vascular end

13 angiopoietin actions are further modified by vascular endothelial growth factor A and integrins.

14 abundance of the proangiogenic growth factor vascular endothelial growth factor A and promoted the pr

15 crovascular endothelial cells in response to vascular endothelial growth factor A and showed less int

16 tration from E6.5, which increases placental vascular endothelial growth factor A and, thus, vascular

17 Vascular endothelial growth factor-A and AKT-3 were vali

18 try identified significant overexpression of vascular endothelial growth factor-A and C as well as p-

19 poptosis, with significant decreases of both vascular endothelial growth factor-A and nephrin protein

20 ucible factor-1alpha-dependent expression of vascular endothelial growth factor-A and platelet-derive

21 Leishmania major increases the expression of vascular endothelial growth factor-A and vascular endoth

22 neoangiogenesis and increased expression of vascular endothelial growth factor-a and vascular endoth

23 x and examined whether these are modified by vascular endothelial growth factors A and C (VEGFA and V

24 e of BM-mononuclear cells in the presence of vascular endothelial growth factors A and C and endothel

25 ncreased IL-1R antagonist, downregulation of vascular endothelial growth factor A, and glomerular and

26 epression of IL-1alpha and beta, IL-1R1, and vascular endothelial growth factor A, and upregulation o

27 et genes, such as matrix metalloproteinases, vascular endothelial growth factor-A, and chemokine (C-C

28 g against CD31 (vascular endothelial cells), vascular endothelial growth factor-A, and D2-40 (lymphat

29 ced angiogenesis and decreases expression of vascular endothelial growth factor A, angiopoietin 1, an

30 thelial sprouting and vascular leak, such as vascular endothelial growth factor A, are well described

31 rkers and the angiogenesis-related proteins: vascular endothelial growth factor-A, Arginase-1, and CC

32 lase, methylthioadenosine phosphorylase, and vascular endothelial growth factor-A as potential therap

33 ctivated PlexinD1 enhanced the expression of vascular endothelial growth factor-A, but not of inflamm

34 o, ramipril was associated with increases in vascular endothelial growth factor-A by 38% (95% confide

35 rs of proliferation and angiogenesis (Ki-67, vascular endothelial growth factors A/C, vascular endoth

36 growth factor beta 1, alpha 2 macroglobulin, vascular endothelial growth factor A, connective tissue

37 dependent on temporal and spatial changes in vascular endothelial growth factor-A distribution.

38 at significantly decreased the expression of vascular endothelial growth factor, a down target of HIF

39 Consistently, oxidative stress-induced vascular endothelial growth factor A expression was sign

40 ing SerRS to the nucleus where it attenuates vascular endothelial growth factor A expression.

41 ors and then is terminated by an increase in vascular endothelial growth factor A expression.

42 a biomarkers of angiogenesis/arteriogenesis (vascular endothelial growth factor-A, fibroblast growth

43 r zinc finger transcription activator of the vascular endothelial growth factor A gene-has recently e

44 progenitor cell differentiation factor, and vascular endothelial growth factor, a growth factor impo

45 Bevacizumab, a monoclonal antibody against vascular endothelial growth factor A, has shown clinical

46 ody Fab that neutralizes all active forms of vascular endothelial growth factor A--has been evaluated

47 eukin-8 and interleukin-13 higher in AML and vascular endothelial growth factor A higher in MDS.

48 atation of dermal microvessels stimulated by vascular endothelial growth factor A, histamine, and thr

49 oxide synthase-2 and decreased expression of vascular endothelial growth factor A in the OB, striatum

50 responses to fibroblast growth factor-2 and vascular endothelial growth factor-A in "motheaten viabl

51 nesis is associated with lower expression of vascular endothelial growth factor-A in integrin beta5-d

52 esis by releasing extracellular matrix-bound vascular endothelial growth factor A, increasing its bio

53 Syx knockdown in vitro impairs vascular endothelial growth factor-A-induced endothelial

54 At the molecular level, we observe that vascular endothelial growth factor A induces nuclear acc

55 oxidative stress-induced ROS generation and vascular endothelial growth factor A induction, thus pre

56 Vascular endothelial growth factor-A is also highly expr

57 mab, a humanized monoclonal antibody against vascular endothelial growth factor A, is currently appro

58 cription polymerase chain reaction; and with vascular endothelial growth factor A isoforms using enzy

59 However, the serum vascular endothelial growth factor-A level was significa

60 r resulted in reduced tumor growth, although vascular endothelial growth factor-A levels and vascular

61 trate that FGF upregulated the production of vascular endothelial growth factor A mainly by increasin

62 us also inhibited Akt and p38 stimulation by vascular endothelial growth factor, a major driver of an

63 tes Flt1, a naturally occurring inhibitor of vascular endothelial growth factor-A-mediated angiogenes

64 Vascular endothelial growth factor-A mRNA and protein ex

65 that the RBP HuR (a.k.a. Elavl1) stabilizes vascular endothelial growth factor-A mRNA, a potent angi

66 the actions of vascular permeability factor/vascular endothelial growth factor-A on both tumor endot

67 urther increased when HemECs were exposed to vascular endothelial growth factor-A or tumor necrosis f

68 These cells secrete vascular endothelial growth factor (a potent proangiogen

69 increased expression of functionally active vascular endothelial growth factor, a potent vascular pe

70 ptors present in dermal fibroblasts restores vascular endothelial growth factor A production by these

71 o exogenous Ang-2 led to decreased levels of vascular endothelial growth factor-A protein.

72 ally impaired and produce reduced amounts of vascular endothelial growth factor A, resulting in defic

73 d phosphatidylinositol 3-kinase and inhibits vascular endothelial growth factor A secretion by tumor

74 Maintenance of LSEC differentiation requires vascular endothelial growth factor-A stimulation of nitr

75 -1alpha axis in CLL-BMSCs with production of vascular endothelial growth factor, a survival factor fo

76 Vascular endothelial growth factor, a target of the TGF-

77 Anti-vascular endothelial growth factor-A therapies are only

78 The two most abundant secreted isoforms of vascular endothelial growth factor A (VEGF(165) and VEGF

79 Vascular endothelial growth factor A (VEGF) activates NF

80 er target the proangiogenesis growth factor, vascular endothelial growth factor A (VEGF) by preventin

81 Vascular endothelial growth factor A (VEGF) is a crucial

82 Genome wide studies indicate that vascular endothelial growth factor A (VEGF) is associate

83 rk was designed to determine the role of the vascular endothelial growth factor A (VEGF) isoforms dur

84 Vascular endothelial growth factor A (VEGF) likely plays

85 vo and the action of alcohol, glutamate, and vascular endothelial growth factor A (VEGF) on activity,

86 tor tyrosine kinase VEGFR2 after binding the vascular endothelial growth factor A (VEGF) to enhance a

87 are associated with increased expression of vascular endothelial growth factor A (VEGF), a potent en

88 n was parallel to an increased expression of vascular endothelial growth factor A (VEGF).

89 ges were characterized by high expression of vascular endothelial growth factor A (VEGF).

90 These effects were linked to decreased vascular endothelial growth factor A (VEGF-A) and angiop

91 The aim of this study was to validate vascular endothelial growth factor A (VEGF-A) and epider

92 Vascular endothelial growth factor A (VEGF-A) and its re

93 The addition of vascular endothelial growth factor A (VEGF-A) and medium

94 planation for such diversity at the level of vascular endothelial growth factor A (VEGF-A) and other

95 he balance between corneal concentrations of vascular endothelial growth factor A (VEGF-A) and the so

96 KSHV induced robust vascular endothelial growth factor A (VEGF-A) and VEGF-C

97 Proteome profiling identified vascular endothelial growth factor A (VEGF-A) as the mai

98 ct of hypoxia on VV infection, we found that vascular endothelial growth factor A (VEGF-A) augments o

99 BMP4 expression was negatively regulated by vascular endothelial growth factor A (VEGF-A) by way of

100 Vascular endothelial growth factor A (VEGF-A) can play b

101 High baseline plasma vascular endothelial growth factor A (VEGF-A) concentrat

102 Herein, we report that vascular endothelial growth factor A (VEGF-A) engages th

103 epithelial phenotype was enhanced following vascular endothelial growth factor A (VEGF-A) exposure.

104 Everolimus inhibits vascular endothelial growth factor A (VEGF-A) expression

105 use of reduced B-cell lymphoma 2 (BCL-2) and vascular endothelial growth factor A (VEGF-A) expression

106 chain of Myosin IIA, resulting in augmented vascular endothelial growth factor A (VEGF-A) expression

107 ChIP analysis of the human vascular endothelial growth factor A (VEGF-A) gene, a kn

108 transporter (xCT), interleukin 6 (IL-6), and vascular endothelial growth factor A (VEGF-A) genes.

109 Increased vascular endothelial growth factor A (VEGF-A) has been i

110 Esm1 expression is induced by the vascular endothelial growth factor A (VEGF-A) in endothe

111 To determine the importance of vascular endothelial growth factor A (VEGF-A) in this sy

112 angioma-derived stem cells for expression of vascular endothelial growth factor A (VEGF-A) in vitro a

113 Vascular endothelial growth factor A (VEGF-A) is a maste

114 Vascular endothelial growth factor A (VEGF-A) is a poten

115 Vascular endothelial growth factor A (VEGF-A) is a poten

116 Vascular endothelial growth factor A (VEGF-A) is a requi

117 Vascular endothelial growth factor A (VEGF-A) is a valid

118 Vascular endothelial growth factor A (VEGF-A) is best kn

119 Vascular endothelial growth factor A (VEGF-A) is one of

120 l vision, and although the angiogenic factor vascular endothelial growth factor A (VEGF-A) is present

121 The transcript of the angiogenic factor vascular endothelial growth factor A (VEGF-A) is subject

122 ies suggest that circulating levels of short vascular endothelial growth factor A (VEGF-A) isoforms,

123 Tumor vascular endothelial growth factor A (VEGF-A) level may

124 atment, there was a rapid increase in plasma vascular endothelial growth factor A (VEGF-A) levels and

125 The cytokines IL-1beta and vascular endothelial growth factor A (VEGF-A) modulate a

126 Vascular endothelial growth factor A (VEGF-A) mRNA and h

127 kade was more effective at reducing CNV than vascular endothelial growth factor A (VEGF-A) neutraliza

128 Vascular endothelial growth factor A (VEGF-A) produced l

129 Everolimus can reduce vascular endothelial growth factor A (VEGF-A) production

130 e to evaluate retrograde axonal transport of vascular endothelial growth factor A (VEGF-A) protein to

131 Vascular endothelial growth factor A (VEGF-A) regulates

132 KEY POINTS: Progressive depletion of all vascular endothelial growth factor A (VEGF-A) splice iso

133 helial cell migration, and tube formation in vascular endothelial growth factor A (VEGF-A) stimulated

134 lated SMAD1/5/8 (phospho-SMAD), osterix, and vascular endothelial growth factor A (VEGF-A) was carrie

135 occurs despite higher circulating levels of vascular endothelial growth factor A (VEGF-A), a key reg

136 oproteinases-1 (TIMP1), beta2-Microglobulin, Vascular Endothelial Growth Factor A (VEGF-A), and clust

137 f two principal effectors of vasculogenesis, vascular endothelial growth factor A (VEGF-A), and plate

138 Tumor-derived vascular endothelial growth factor A (VEGF-A), interleuk

139 Three classes of growth factors [vascular endothelial growth factor A (VEGF-A), platelet-

140 Vascular endothelial growth factor A (VEGF-A), the found

141 e and bind to the Flk-1/KDR receptor for the vascular endothelial growth factor A (VEGF-A), which is

142 it reduced hematopoietic potential caused by vascular endothelial growth factor A (Vegf-a)-dependent

143 ociated with a decrease in the expression of vascular endothelial growth factor A (VEGF-A).

144 glucose inhibits EMT by reducing myocardial vascular endothelial growth factor A (VEGF-A).

145 y within the endogenous chromosomal locus of vascular endothelial growth factor A (VEGF-A).

146 tumour growth and is induced principally by vascular endothelial growth factor A (VEGF-A).

147 (for example, carbonic anhydrase 9 (CA9) and vascular endothelial growth factor A (VEGF-A).

148 Vascular endothelial growth factor-A (VEGF) is critical

149 Vascular endothelial growth factor-A (VEGF) is produced

150 Vascular endothelial growth factor-A (VEGF) is the maste

151 We demonstrate that vascular endothelial growth factor-A (VEGF) rapidly indu

152 Vascular endothelial growth factor-A (VEGF), a potent an

153 Following acute exercise, protein levels of vascular endothelial growth factor-A (VEGF), endostatin

154 Bevacizumab is a monoclonal antibody to vascular endothelial growth factor-A (VEGF).

155 Vascular endothelial growth factor-A (VEGF-A) acts via 2

156 omeruli, the proendothelial survival factors vascular endothelial growth factor-A (VEGF-A) and angiop

157 on, tube formation, and increased release of vascular endothelial growth factor-A (VEGF-A) and basic

158 t tamoxifen decreased the mRNA expression of vascular endothelial growth factor-A (VEGF-A) and increa

159 Vascular endothelial growth factor-A (VEGF-A) and its 2

160 ed retinal function and an imbalance between vascular endothelial growth factor-A (VEGF-A) and pigmen

161 is, collagen quantity, and the expression of vascular endothelial growth factor-A (VEGF-A) and VEGF-C

162 bservation that therapeutic agents targeting vascular endothelial growth factor-A (VEGF-A) associate

163 'Vascular endothelial growth factor-A (VEGF-A) blockade h

164 Vascular Endothelial Growth Factor-A (VEGF-A) can be gen

165 Vascular endothelial growth factor-A (VEGF-A) contribute

166 In contrast, inhibition of vascular endothelial growth factor-A (VEGF-A) did not re

167 Vascular endothelial growth factor-A (VEGF-A) expression

168 ed tumor angiogenesis through the release of vascular endothelial growth factor-A (VEGF-A) from cance

169 Splicing of the human vascular endothelial growth factor-A (VEGF-A) gene has b

170 ut not GLI1, binds to and enhances the human vascular endothelial growth factor-A (VEGF-A) gene promo

171 Vascular endothelial growth factor-A (VEGF-A) has recent

172 tes mRNA and protein expression of epidermal vascular endothelial growth factor-A (VEGF-A) in normal

173 Vascular endothelial growth factor-A (VEGF-A) is one of

174 Vascular endothelial growth factor-A (VEGF-A) is require

175 Vascular endothelial growth factor-A (VEGF-A) is strongl

176 Vascular endothelial growth factor-A (VEGF-A) is thought

177 Unregulated expression of vascular endothelial growth factor-A (VEGF-A) plays an i

178 implicate a mechanism wherein tumor-derived vascular endothelial growth factor-A (VEGF-A) promotes t

179 nthetic modified RNA (modRNA) encoding human vascular endothelial growth factor-A (VEGF-A) results in

180 The tight regulation of vascular endothelial growth factor-A (VEGF-A) signaling

181 Vascular endothelial growth factor-A (VEGF-A) signaling

182 Vascular endothelial growth factor-A (VEGF-A) surprising

183 tion resolution by suppressing expression of vascular endothelial growth factor-A (VEGF-A), a macroph

184 r-2 (FGF-2), hepatocyte growth factor (HGF), vascular endothelial growth factor-A (VEGF-A), and vascu

185 ene) to increase the beta cell production of vascular endothelial growth factor-A (VEGF-A), angiopoie

186 M had significantly higher concentrations of vascular endothelial growth factor-A (VEGF-A), brain-der

187 action with one of its main natural ligands, vascular endothelial growth factor-A (VEGF-A), contribut

188 binant humanized monoclonal antibody against vascular endothelial growth factor-A (VEGF-A), has clini

189 The longer splice isoforms of vascular endothelial growth factor-A (VEGF-A), including

190 n derived neurotrophic growth factor (BDNF), vascular endothelial growth factor-A (VEGF-A), insulin-l

191 Prespecified biomarkers included plasma vascular endothelial growth factor-A (VEGF-A), protein e

192 -angiogenic factors and molecules, including vascular endothelial growth factor-A (VEGF-A), SRY-box c

193 Vascular endothelial growth factor-A (VEGF-A), the best

194 he role of a novel antiangiogenic isoform of vascular endothelial growth factor-A (VEGF-A), VEGF-A165

195 define the mechanisms by which PTK7 promotes vascular endothelial growth factor-A (VEGF-A)-induced an

196 ndent transcription of the angiogenic factor vascular endothelial growth factor-A (VEGF-A).

197 id-sclera complex were major contributors of vascular endothelial growth factor-A (VEGF-A).

198 ls typify pathologic angiogenesis induced by vascular endothelial growth factor-A (VEGF-A).

199 ticity, including HIF-1alpha and its target, vascular endothelial growth factor-A (VEGF-A).

200 hrough the cooperation of beta-defensins and vascular endothelial growth factor-A (Vegf-A).

201 network is illustrated by the actions of the vascular endothelial growth factor-A (VEGF-A)/VEGF recep

202 The effects of vascular endothelial growth factor-A (VEGF-A/VEGF) and i

203 (rAAV) (5 x 10(12) viral particles encoding vascular endothelial growth factor-A [VEGF-A] or thymosi

204 a 4-fold elevation in proangiogenic factors (vascular endothelial growth factor-A [VEGF-A], stromal c

205 The CCR2-mediated recruitment of a vascular endothelial growth factor A(VEGF-A)-expressing

206 Vascular endothelial growth factor-A, VEGF-C, and VEGF-R

207 d new blood vessel sprouts is coordinated by vascular endothelial growth factor A (VEGFA) and Delta-l

208 Vascular endothelial growth factor A (VEGFA) and the typ

209 Hepatocyte growth factor (HGF) and vascular endothelial growth factor A (VEGFA) are paracri

210 a-induced factor 1a (Hif1a) and secretion of vascular endothelial growth factor A (Vegfa) by starved

211 Production of Vascular Endothelial Growth Factor A (VEGFA) by the visc

212 proper through epithelial cell expression of vascular endothelial growth factor A (VEGFA) dependent u

213 ecent evidence indicates a specific role for vascular endothelial growth factor a (Vegfa) during arte

214 Vascular endothelial growth factor A (VEGFA) expression

215 d by breaching Bruch's membrane and inducing vascular endothelial growth factor A (VEGFa) expression

216 Murine neural tube vascular endothelial growth factor A (VEGFA) expression

217 sease progression through adipocyte-mediated vascular endothelial growth factor A (VEGFA) expression

218 Vascular endothelial growth factor A (Vegfa) has importa

219 of hypoxia inducible factor (HIF)-1alpha and vascular endothelial growth factor A (VEGFA) in MDA-231

220 at miR-1/206 directly regulate the levels of Vascular endothelial growth factor A (VegfA) in muscle,

221 egulation of angiogenic mediators, including vascular endothelial growth factor A (VEGFA) in OIR.

222 Remarkably, concomitant deletion of vascular endothelial growth factor A (VEGFA) in the mous

223 In the present study, we show that vascular endothelial growth factor A (VEGFA) induces Pyk

224 Vascular endothelial growth factor A (VEGFA) is a key fa

225 Vascular endothelial growth factor a (Vegfa) is essentia

226 The HIF-1alpha target gene Vascular Endothelial Growth Factor A (VEGFA) is expresse

227 Although vascular endothelial growth factor A (Vegfa) is required

228 Interestingly, vascular endothelial growth factor A (Vegfa) levels in t

229 dr expression to enable the DH to respond to vascular endothelial growth factor A (VEGFA) ligand from

230 tes and glomerular endothelial cells through vascular endothelial growth factor A (VEGFA) maintains a

231 Here, we show that vascular endothelial growth factor A (VEGFA) mRNA in mam

232 IL-6 activated the STAT3/vascular endothelial growth factor A (VEGFA) pathway dir

233 Vascular endothelial growth factor A (VEGFA) plays an im

234 Vascular endothelial growth factor A (VEGFA) production

235 in- or rapamycin-evoked mitophagy, increased vascular endothelial growth factor A (VEGFA) production,

236 deletion of hypoxia-response element in the vascular endothelial growth factor A (VEGFA) promoter sh

237 ty of efferocytosis and subsequently blunted vascular endothelial growth factor A (VEGFA) release.

238 oxia-inducible factor 1alpha (Hif1alpha) and vascular endothelial growth factor A (Vegfa) transcripts

239 y of the genes assayed, but up-regulation of vascular endothelial growth factor A (VEGFA) was observe

240 Expression of vascular endothelial growth factor A (VEGFA) was rapidly

241 Vascular endothelial growth factor A (VEGFA), a major re

242 Glucose deprivation induced the secretion of vascular endothelial growth factor A (VEGFA), basic fibr

243 luding those for interleukin-6 (IL-6), IL-8, vascular endothelial growth factor A (VEGFA), cyclin D,

244 Fibroblast growth factor 9 (FGF9), vascular endothelial growth factor A (VEGFA), interleuki

245 sms of Src-PLD1-PKCgamma-cPLA2 activation by vascular endothelial growth factor A (VEGFA), we studied

246 and upregulated paracrine factors, including vascular endothelial growth factor A (Vegfa).

247 s harbored focal gains at 6p21 incorporating vascular endothelial growth factor A (VEGFA).

248 ood-brain barrier opening, via production of vascular endothelial growth factor A (VEGFA).

249 (P </= 0.003) of rs3736265 with a variant in vascular endothelial growth factor A (VEGFA, rs3025033),

250 Expression of vascular endothelial growth factor-A (VEGFA) by tumour-a

251 s of small interfering RNA (siRNA) targeting vascular endothelial growth factor-A (VEGFA) or its rece

252 ned to regulate the endogenous gene encoding vascular endothelial growth factor-A (Vegfa).

253 Here we report an RNA switch in human vascular endothelial growth factor-A (VEGFA, also known

254 d; angiogenic and vessel maturation factors (vascular endothelial growth factor a [VEGFa], angiopoiet

255 w that L. major infection initiates enhanced vascular endothelial growth factor-A/VEGFR-2 signaling a

256 Vascular endothelial growth factor A was measured by Lum

257 Vascular endothelial growth factor A was measured by mul

258 ible factor-1alpha protein and expression of vascular endothelial growth factor-A were increased in e

259 rstitial cells (mesenchymal cells), requires vascular endothelial growth factor A, which stimulates m

260 essel formation in endothelial cells through vascular endothelial growth factor-A, which was up-regul

261 ody Fab that neutralizes all active forms of vascular endothelial growth factor A--with photodynamic