ライフサイエンスコーパス: vascular lesion

1 ion of monocytes and T cells around sites of vascular lesion.

2 rophile infiltrates, and Shiga toxin-induced vascular lesions.

3 the pulmonary arterioles by the formation of vascular lesions.

4 tively active Notch1 induced similar hepatic vascular lesions.

5 hotothermolysis" is widely used for treating vascular lesions.

6 and lymph node lesions; germ cell tumors and vascular lesions.

7 (BM-derived) immune cells that migrate into vascular lesions.

8 retinopathy and contribute to the resultant vascular lesions.

9 sappearance, a desired endpoint for treating vascular lesions.

10 Animals in group 2 never developed vascular lesions.

11 hemangiomas, and may be useful for cutaneous vascular lesions.

12 n in nude mice, form lumen-obliterating lung vascular lesions.

13 oss of PPARgamma expression in their complex vascular lesions.

14 oup 5 recipients accepted allografts without vascular lesions.

15 to protect against diabetes-induced retinal vascular lesions.

16 cells (VSMCs) contribute to the formation of vascular lesions.

17 enchymal-like cells in obstructive pulmonary vascular lesions.

18 -recognized component of the pathogenesis of vascular lesions.

19 onship between elevated PAI-1 expression and vascular lesions.

20 VSM) mitogen that is expressed in developing vascular lesions.

21 ssel wall or be incorporated into developing vascular lesions.

22 ould be monitored for the development of new vascular lesions.

23 olic regulatory genes in the pathogenesis of vascular lesions.

24 ent also reduced the incidence and extent of vascular lesions.

25 erial extravasation or posttraumatic splenic vascular lesions.

26 the Ink CKI, p16(Ink4), is not expressed in vascular lesions.

27 rdinating the cellular events that result in vascular lesions.

28 ces the formation of thrombus and neointimal vascular lesions.

29 completely suppressed enhanced formation of vascular lesions.

30 f vascular hypertrophy and the generation of vascular lesions.

31 herapeutic tool in the treatment of SMC-rich vascular lesions.

32 roteins expressed by endothelium at sites of vascular lesions.

33 atherosclerosis and have fewer monocytes in vascular lesions.

34 ting mechanisms linked to the development of vascular lesions.

35 oses an individual to develop HHT-associated vascular lesions.

36 agement should emphasize scoring of specific vascular lesions.

37 es induced apoptosis and acute regression of vascular lesions.

38 withdrawal is associated with regression of vascular lesions.

39 et cell sensitization and the development of vascular lesions.

40 creased left ventricular performance without vascular lesions.

41 opment of atherosclerotic and injury-induced vascular lesions.

42 ion of a disease-prone cell type within some vascular lesions.

43 g occurred in subjects both with and without vascular lesions.

44 d PCR was performed only in the samples from vascular lesions.

45 oles in the inflammatory cell recruitment to vascular lesions.

46 t may be relevant to the pathogenesis of HHT vascular lesions.

47 ion diet resulted in reduced IK17 binding to vascular lesions.

48 tients, Th1 and Th17 cells co-existed in the vascular lesions.

49 endothelial cells in occlusive and plexiform vascular lesions.

50 h17 but not the Th1 arm in the blood and the vascular lesions.

51 appearance of skeletal elements in calcified vascular lesions.

52 al target for drug development against these vascular lesions.

53 immunohistochemistry for evidence of complex vascular lesions.

54 Seventy consecutive patients provided a vascular lesion, a blood sample, and 36 subgingival samp

55 ificant Alzheimer disease neuropathology and vascular lesions, a cognitively and physically intact ce

56 Cerebral cavernous malformations (CCMs) are vascular lesions affecting the central nervous system.

57 KS-derived spindle cells induce vascular lesions and display enhanced vascular permeabil

58 ere receiving sirolimus had no recurrence of vascular lesions and had decreased vascular proliferatio

59 These vascular lesions and other classic histologic features w

60 hydes may exert potent biological effects in vascular lesions and other sites of inflammation.

61 ed the importance of comparing patients with vascular lesions and patients with neurodegenerative dis

62 n pancreas transplants with specification of vascular lesions and prospects for defining a vasculariz

63 found that TopBP1 expression was reduced in vascular lesions and pulmonary endothelial cells isolate

64 asL) expression has been detected in chronic vascular lesions, and Fas-mediated apoptosis of vascular

65 NFT deposition, vascular lesions, and high NPC scorewere associated with

66 of neurofibrillary tangles, amyloid plaques, vascular lesions, and Lewy bodies.

67 microbleeds, coexistent ischemia, associated vascular lesions, and markers of hemorrhage expansion is

68 data from primary cells isolated from human vascular lesions, and we found that glucose sensitivity

69 matory chorioretinal or inflammatory retinal vascular lesions, anterior chamber cell grade, vitreous

70 Before intramural coronary vascular lesions appeared at week 4 of ALDOST, we found

71 re of the antiphospholipid syndrome, chronic vascular lesions are common, particularly in patients wi

72 Because the vascular lesions are homogeneously distributed throughou

73 The vascular lesions associated with autoimmune small-vessel

74 an MADH4 mutation should be screened for the vascular lesions associated with hereditary haemorrhagic

75 st that the mTORC pathway is involved in the vascular lesions associated with the antiphospholipid sy

76 From P15 onward, Vldlr(-/-) retinas develop vascular lesions associated with the local upregulation

77 entification and treatment of the underlying vascular lesions at an early stage can also prevent subs

78 hrombin mediates the formation of neointimal vascular lesions at sites of mechanical vascular injury

79 neurofibrillary tangle (NFT) pathology, and vascular lesion burden were determined.

80 f smooth muscle cells is a common feature of vascular lesions but its pathophysiological significance

81 s well established in both benign tumors and vascular lesions, but has only limited applicability for

82 rime monocytes for enhanced recruitment into vascular lesions by increasing monocytes' responsiveness

83 ne may play an important role in stabilizing vascular lesions by promoting SMC collagen synthesis.

84 We show that blocking formation of these vascular lesions by two independent mechanisms, tamoxife

85 ontribute to the pathogenesis of Stx-induced vascular lesions by up-regulating toxin receptor express

86 Cerebral cavernous malformations (CCM) are vascular lesions causing seizures and stroke.

87 Our data suggest that in the vascular lesions characteristic for GCA, a subset of mac

88 connexin 43 downregulation promotes retinal vascular lesions characteristic of diabetic retinopathy

89 ositive capillary cells at 6 to 8 months and vascular lesions characteristic of retinopathy at 18 mon

90 The etiology and pathogenesis of the vascular lesions characterizing primary pulmonary hypert

91 Venous malformations are low-flow vascular lesions consisting of disorganized thin-walled

92 percortisolemia induces diabetes or diabetic vascular lesions contribute to mania, an overlapping fun

93 RPE and vascular lesions develop secondarily with increasing pen

94 Vascular lesions developed randomly without regard for v

95 l-animal model in which diabetes accelerates vascular lesion development.

96 ecular link between diabetes and accelerated vascular lesion development.

97 ironment has been proposed to exist within a vascular lesion due to intimal or medial cell proliferat

98 Most orbital vascular lesions express VEGF receptors, which may sugge

99 Despite more occlusive vascular lesions, fasudil also markedly reduced right ve

100 plications of overzealous needling of such a vascular lesion for histopathological diagnosis as in ou

101 avernous malformations (CCMs) in which focal vascular lesions form throughout the central nervous sys

102 Pyogenic granulomas, acquired vascular lesions, form on the ocular or palpebral surfac

103 mmation has been suggested to play a role in vascular lesion formation after angioplasty.

104 Ionizing radiation has been shown to reduce vascular lesion formation after balloon overstretch inju

105 It is postulated that vascular lesion formation and remodeling involves a bala

106 we show that Id3a protein is induced during vascular lesion formation and that Id3a expression peaks

107 myofibroblasts contribute to the process of vascular lesion formation by proliferating, synthesizing

108 pled receptors (GPRCs) and may contribute to vascular lesion formation by stimulating proliferation o

109 (KO) mice and showed that the A2bAR prevents vascular lesion formation in an injury model that resemb

110 ents in the response to injury that typifies vascular lesion formation in atherosclerosis and resteno

111 been implicated as an important mediator of vascular lesion formation in atherosclerosis and resteno

112 ory properties, in inhibiting injury-induced vascular lesion formation in both naive and immunologica

113 Here, we show that during vascular lesion formation in rats, an alternative isofor

114 by thrombin in vitro and is associated with vascular lesion formation in vivo.

115 e of GATA-6 downregulation in injury-induced vascular lesion formation, adenoviral vectors were used

116 decrease the extent of granulation tissue or vascular lesion formation, and that the vascularization

117 termine whether endothelial Akt could affect vascular lesion formation, mutant mice with a constituti

118 isoform that acts to limit SMC growth during vascular lesion formation, providing the first evidence

119 ing DNA replication, VSMC proliferation, and vascular lesion formation, suggesting that PGC-1beta may

120 Given that Ang II promotes vascular lesion formation, we examined whether this matr

121 th muscle cells (SMCs) and may contribute to vascular lesion formation.

122 a novel and critical mediator that inhibits vascular lesion formation.

123 SMCs) is key to understanding and modulating vascular lesion formation.

124 ted Ang II-responsive genes that may mediate vascular lesion formation.

125 angioplasty might have an important role in vascular lesion formation.

126 udies to dissect the contributions of ROS to vascular lesion formation.

127 effect on the development and progression of vascular lesion formation.

128 harmacological PPARgamma agonists attenuates vascular lesion formation.

129 ate VSMC growth and matrix production during vascular lesion formation.

130 to vascular injury plays a critical role in vascular lesion formation.

131 induced VSMC migration, an important step in vascular lesion formation.

132 cated in pathological cardiac remodeling and vascular lesion formation.

133 expression in vivo and in protecting against vascular lesion formation.

134 d in NAD(P)H oxidase-dependent manner during vascular lesion formation.

135 luent density were surgically implanted, and vascular lesion formations at distal graft-vessel anasto

136 both Ang II and macrophages was observed in vascular lesions from all 5 monkeys after regression of

137 nd (TRAIL) immunoreactivity within pulmonary vascular lesions from patients with idiopathic PAH and a

138 I vessels versus larger vessels: the type I vascular lesion has a large component of proliferating m

139 years, which was clinically identified as a vascular lesion in the area of calcaneus and talus.

140 extravasation in seven patients and splenic vascular lesions in 19 patients.

141 tension (PH) in 99 (63%) patients and peptic/vascular lesions in 57 (37%).

142 e prognostic significance of common specific vascular lesions in acute allograft rejection.

143 nderstand the pathophysiology underlying the vascular lesions in CCM, it is critical to develop a rep

144 tions to the use of the pulsed dye laser for vascular lesions in children are discussed.

145 s may provide a useful approach for reducing vascular lesions in diabetic retinopathy.

146 critical role in the development of retinal vascular lesions in early DR.

147 etic peptides recognize both parenchymal and vascular lesions in FBD patients.

148 t may be a novel target for the treatment of vascular lesions in HHT2.

149 Studies of vascular lesions in humans and animal models documented

150 results support a role for various placental vascular lesions in medically indicated and spontaneous

151 ith the constitutively active Rac1QL induced vascular lesions in mice that were remarkably similar to

152 nt with a role in the formation of pulmonary vascular lesions in PPH, and reduced BMPR-II expression

153 olerance induction and prevention of chronic vascular lesions in recipients of simultaneous heart and

154 The reduction of vascular lesions in resveratrol-treated Vldlr(-/-) mice

155 The discovery of complex vascular lesions in SHIV-nef- but not SIV-infected anima

156 (PAH), which is characterized by obstructive vascular lesions in small arteries.

157 direct pressure gradient measurements across vascular lesions in swine.

158 We observed vascular lesions in the brains of 55% of the double-muta

159 These mice developed age-dependent vascular lesions in the skin, extremities, oral cavity a

160 It is suggested that the antral vascular lesions in these patients may represent a compo

161 chanisms may contribute to acute and chronic vascular lesions in transplants.

162 vesicles, as has been described in calcified vascular lesions in vivo as well as in bone and teeth.

163 mediated tissue damage is the development of vascular lesions in which endothelial cells are swollen

164 ically abnormal smooth muscle cells in early vascular lesions included elastin, among other matrix el

165 hrix jacchus) develop characteristic retinal vascular lesions including macular edema (ME), a leading

166 Tissue factor, which is expressed in vascular lesions, increases thrombin production, blood c

167 derived cells from p27(-/-) mice repopulated vascular lesions induced by mechanical injury in p27(+/+

168 ons, the majority are autopsy series and the vascular lesion involves the bronchial arteries.

169 To test the hypothesis that the KD vascular lesion is an activated T lymphocyte-dependent p

170 rotid Doppler followed by cMRA if a cervical vascular lesion is suspected.

171 morrhagic telangiectasia (HHT), the hallmark vascular lesion is termed an arteriovenous malformation,

172 ease of o,o'-dityrosine in LDL isolated from vascular lesions is consistent with the hypothesis that

173 Medical therapy for vascular lesions is in its infancy but shows promise.

174 A hallmark of vascular lesions is the phenotypic modulation of vascula

175 nas were analyzed for vascular permeability, vascular lesions, leukostasis, morphologic changes of mi

176 Although hemangiomas are well-known vascular lesions, little is known about the mechanisms t

177 ibutes to the development and progression of vascular lesions, little is known regarding the molecula

178 h has shown that the extent and depth of the vascular lesion may be contributing factors in promoting

179 ragility, leading to the suggestion that the vascular lesion may be of a secondary nature.

180 proved recognition of these often-undetected vascular lesions may be important for identification of

181 Stx-induced intestinal, renal, and CNS vascular lesions may involve a localized production of p

182 NHL and benign cutaneous vascular lesions not associated with AIDS were used as n

183 The vascular lesion of CR, transplant vascular sclerosis (TV

184 Vascular lesions of aortic isografts and allografts were

185 ect and display different characteristics of vascular lesions of clinical and/or research interest.

186 of oxidative stress is known to inhibit the vascular lesions of early diabetic retinopathy, and we i

187 suppressing proinflammatory cytokines in the vascular lesions of GCA.

188 Direct assessment of the vascular lesions of model animals in vivo is important f

189 xamined for the development of early retinal vascular lesions of NPDR and compared to littermates at

190 inflammatory cell infiltration in pulmonary vascular lesions of patients with idiopathic pulmonary a

191 ytes, and dendritic cells are present in the vascular lesions of PH, whether in idiopathic pulmonary

192 Finally, aortic vascular lesions of the aspirin-treated animals showed 5

193 Cerebral cavernous malformations (CCMs) are vascular lesions of the central nervous system appearing

194 CCMs) are sporadically acquired or inherited vascular lesions of the central nervous system consistin

195 Vascular lesions of the orbit, although not malignant, c

196 and their subtypes are expressed on selected vascular lesions of the orbit.

197 nd of the alpha1-adrenergic receptor (AR) on vascular lesions of the retinopathy in experimentally di

198 In cardiac allografts, mild vascular lesions of varying NI were detectable by day 30

199 In patients who require transplantation, vascular lesions often recur.

200 y 2015) who developed a new-onset, expanding vascular lesion on his right leg.

201 sequencing of the well-demarcated, blanching vascular lesion on the lateral right shin revealed a som

202 Distinctive vascular lesions on chest radiographs and CT scans in Ei

203 Characterization of vascular lesions on the basis of visual estimation of pe

204 (P = 0.0002) and the development of punctate vascular lesions on the colonic surface, which correspon

205 ues harboring only dysplasia with or without vascular lesions onto nude mice was able to yield HCCs c

206 sheath, epidermal inclusion cysts, lipomas, vascular lesions, peripheral-nerve tumours, skin cancers

207 In response to agonists produced at vascular lesions, platelets release a host of components

208 These vascular lesions potentially mark cerebrovascular frailt

209 ion of 3-chlorotyrosine in HDL isolated from vascular lesions raises the possibility that MPO, by vir

210 tion of 3-nitrotyrosine in LDL isolated from vascular lesions raises the possibility that NO, by virt

211 ts against inflammaging, limiting kidney and vascular lesions related to aging.

212 etinal stages long before the development of vascular lesions representing the classic hallmark of di

213 Intraosseous vascular lesions resemble orbital cavernous venous malfo

214 Vascular lesions resulting from injury are characterized

215 cant correlation between acute rejection and vascular lesion severity in the WF-LEW combination (r=0.

216 g factor in multiple vascular disorders, and vascular lesion severity is tempered by enhanced endothe

217 RNA sequencing of the vascular lesions shows abundant expression of molecules

218 diagnose and assess the risk of intracranial vascular lesions such as atherosclerosis, aneurysms, dis

219 pathogenic similarities between TV and other vascular lesions such as atherosclerosis.

220 Pelvic vascular lesions such as pseudoaneurysms and arterioveno

221 Vascular lesions such as venopathy and--to a lesser exte

222 l oxidation products known to be enriched in vascular lesions, such as 1-hexadecanoyl-2-oxovalaryl-sn

223 share pathological hallmarks with peripheral vascular lesions, such as increased inflammation and oxi

224 of selected CD4+ T cell specificities in the vascular lesions support the model that giant cell arter

225 tx2e in their blood developed more-extensive vascular lesions than pigs without detectable Stx2e in t

226 us malformations of the brain are congenital vascular lesions that affect 0.01-0.50% of the populatio

227 However, biopsy specimens showed that vascular lesions that can be associated with humoral rej

228 pth the influence of diabetes on the various vascular lesions that cause brain ischemia.

229 vasculature along with formation of multiple vascular lesions that closely resemble human cavernomas

230 in the remodeling of extracellular matrix in vascular lesions that could lead to plaque weakening and

231 The vascular lesions that develop consist of direct arteriov

232 es characterized by complex, lumen-occluding vascular lesions that develop in genetically susceptible

233 ple enchondromas and tested a range of other vascular lesions that enter into the differential diagno

234 vides insight into the nature of the retinal vascular lesions that likely represent a clinical correl

235 d to cerebral cavernous malformations (CCM), vascular lesions that most frequently occur in the brain

236 ovenous malformations (BAVMs) are congenital vascular lesions that often present as cerebral hemorrha

237 iven that mutations were absent in 154 other vascular lesions, the mutation seems to be highly specif

238 iltration of the graft or the development of vascular lesions typical of chronic rejection.

239 at develops in some diabetics was due to the vascular lesions used to characterize the disease.

240 seven patients) and a posttraumatic splenic vascular lesion was 83% (10 of 12 patients) sensitive on

241 the 22 patients with contained injuries, the vascular lesion was visualized only at the arterial phas

242 The sensitivity of CT for detecting vascular lesions was 100%, specificity was 89% (8 of 9),

243 Furthermore, macrophage recruitment to vascular lesions was significantly reduced in EBP50 knoc

244 Three previously undescribed vascular lesions were identified histologically in Eisen

245 owever, the non-AIDS-related NHLs and benign vascular lesions were negative.

246 st this hypothesis, plexiform and concentric vascular lesions were serially microdissected from lung

247 will contribute to our understanding of this vascular lesion, which remains a leading cause of morbid

248 patients with severe PH demonstrates complex vascular lesions, which contain inflammatory cells, we w

249 eserves elastin components of ECM within the vascular lesions, which, at least in part, is modulated

250 sociated with retinal vascular inflammation, vascular lesions with increased leukocyte adhesion and c