ライフサイエンスコーパス: vascular network

1 twork and lymph through a low-pressure, open vascular network.

2 ntly by providing circulating minerals and a vascular network.

3 that these cells followed a pre-established vascular network.

4 S1P receptor-1 (S1P1) stabilizes the primary vascular network.

5 tracellular matrix components and the intact vascular network.

6 ivert blood flow to the developing implanted vascular network.

7 is is critical in the expansion of the tumor vascular network.

8 s required for the formation of a functional vascular network.

9 nd a transparent, macroscopic extracorporeal vascular network.

10 tissue and participate in regeneration of a vascular network.

11 ering requires formation of a de novo stable vascular network.

12 he timely formation of a well differentiated vascular network.

13 d in culture, allantoides assemble a primary vascular network.

14 ensures the formation of a mature and stable vascular network.

15 which shares similarities with formation of vascular network.

16 blood flow for the formation of a functional vascular network.

17 ollicle as well as an ND-GFP interfollicular vascular network.

18 ndirectly prevent further elaboration of the vascular network.

19 d to connect into a characteristic intricate vascular network.

20 ation of angiogenesis and maintenance of the vascular network.

21 orphologically and functionally "normalized" vascular network.

22 ion, and stabilization to establish a mature vascular network.

23 adult mouse intestine contains an intricate vascular network.

24 d results in the rapid formation of a mature vascular network.

25 enes leading to the development of a primary vascular network.

26 angiogenesis and left-right asymmetry of the vascular network.

27 he newly formed vessels into the preexisting vascular network.

28 hormone-producing cell types and an invading vascular network.

29 pectives to engineer the optimal, functional vascular network.

30 ethod for quantifying FAZ at the superficial vascular network.

31 mplexes is transmitted into the intraretinal vascular network.

32 ed MR imaged functional changes in the tumor vascular network.

33 changing the numerical representation of the vascular network.

34 ional responses that form a highly efficient vascular network.

35 4679), suggesting a highly organized hepatic vascular network.

36 eling of primary blood vessels into a mature vascular network.

37 tem enabling brain endothelial cells to form vascular networks.

38 ascular front of developing and pathological vascular networks.

39 migrated through areas devoid of established vascular networks.

40 low-dependent clinical assays and biomimetic vascular networks.

41 underlies the formation of blood vessels and vascular networks.

42 lony-forming cells (ECFCs) to form efficient vascular networks.

43 ux, perfusion, and also development of newer vascular networks.

44 flecting very narrow vessels forming complex vascular networks.

45 and are required for the formation of stable vascular networks.

46 d grafts showed preserved islets and intense vascular networks.

47 genesis is a key process in the formation of vascular networks.

48 well as their subsequent incorporation into vascular networks.

49 ung mesenchyme, and later within ECs forming vascular networks.

50 columnar structures and supplied by matching vascular networks.

51 uent incorporation into functional pulmonary vascular networks.

52 othelial cells required for the expansion of vascular networks.

53 cess by which new vessels form from existing vascular networks.

54 onging cell survival signals and maintaining vascular networks.

55 lar density in both the superficial and deep vascular networks.

56 eep (0.616 mm(2) vs. 0.372 mm(2); P < 0.001) vascular networks.

57 AVM, since it can clearly depict the related vascular networks.

58 eptor 2 (VEGF-R2) expression in peri-infarct vascular networks.

59 nificantly decreased formation of functional vascular networks.

60 ricyte association was improved, with larger vascular networks.

61 restricted vascular leakage, and stabilized vascular networks.

62 scent endothelial cells to form a functional vascular network, a process termed 'angiogenesis'.

63 regulator in the maturation of the lymphatic vascular network affecting valve development and lymphat

64 The plant vascular network also transports water, photosynthates,

65 Here we show that implanted vascular networks anastomose with host vessels through a

66 defects in the development of the placental vascular network and cardiac hypoplasia.

67 including the ability to integrate into the vascular network and express the QH1 antigen.

68 Instead, low-dose TNFalpha stabilizes the vascular network and improves vessel perfusion.

69 would remodel both the VEGFR3(+) pericystic vascular network and larger renal lymphatics that may al

70 MLL1 is overexpressed along the line of vascular network and localized adjacent to endothelial c

71 nsport blood through a high-pressure, closed vascular network and lymph through a low-pressure, open

72 ion to enable user-defined geometries of the vascular network and microfluidic perfusion to control m

73 ial progenitors in stabilizing nascent brain vascular network and provide novel insights into the mol

74 necessary for angioblasts to assemble into a vascular network and to undergo vascular tube formation.

75 Acutely after TBI there is a reduction in vascular network and vascular complexity that are exacer

76 Conditioned media promoted equivalent vascular networks and CAC recruitment with superior effe

77 hat is critical for generation of functional vascular networks and local proliferative ductal alveola

78 Myc-deficient mice fail to develop normal vascular networks and Myc-deficient embryonic stem cells

79 and mesenchymal progenitor cells (MPC) form vascular networks and restore blood flow in ischemic ske

80 form blood vessel-like structures, including vascular networks and sprouts.

81 tion of soluble VEGFR-1 results in malformed vascular networks and the absence of large vessels.

82 genic chemokines in the development of tumor vascular networks and the chemokine binding properties o

83 een causatively linked to the elaboration of vascular networks and the regulation of capillary functi

84 representative areole (region bounded by the vascular network), and represent the volume of tissue wi

85 has an uneven growing front, a less-branched vascular network, and abnormal distribution of dll4-posi

86 , cell type, melanin content, mitotic count, vascular networks, and patients' age.

87 uronal and glial populations, interconnected vascular networks, and ramified microglia.

88 s gap junction-mediated signaling across the vascular network are essential for proper capillary diam

89 ndothelial differentiation into a functional vascular network are incompletely understood.

90 Angiogenesis and the development of a vascular network are required for tumour progression, an

91 Plant vascular networks are central to botanical form, functio

92 The vascular networks are designed following in vivo images

93 Here we show that embryonic vascular networks are strategically positioned to fulfil

94 At the same time, vascular networks are susceptible to regression mediated

95 Leaf vascular networks are well-fitted to investigate this is

96 were explanted and evaluated with regard to vascular network assembly and cell fate; and heterotypic

97 (NK-B), reversibly inhibits endothelial cell vascular network assembly and opposes angiogenesis in th

98 We hypothesized that establishing a local vascular network at the transplantation site would reduc

99 escribe a new phenotypic trait of reticulate vascular networks based on the topology of the nested lo

100 C-rich ECM surrounds Prx1-positive pulmonary vascular networks both in vivo and in tissue culture.

101 dothelial cells and angioblasts) labeled the vascular network but failed to label the spindle-shaped

102 eristics of polypoidal structures, branching vascular networks (BVNs), and origin of PCV using optica

103 onstrate prompt and consistent assembly of a vascular network by human ASCs and endothelial cells and

104 Formation of functionally adequate vascular networks by angiogenesis presents a problem in

105 Interestingly, the disruption of vascular networks by cancer cells was driven by changes

106 -canonical Wnt signalling stabilizes forming vascular networks by reducing endothelial shear sensitiv

107 regulated system, and generated subcutaneous vascular networks capable of systemic EPO release in imm

108 Inhibition of FZD4 in developing retinal vascular networks caused the upregulation of PLVAP, a pr

109 RAF(V600E), PLX4720 extensively modifies the vascular network causing abrogation of hypoxia.

110 with endothelial tubes, resulting in smaller vascular networks compared to those with healthy pericyt

111 ical serial sections demonstrated that a new vascular network composed of venous-venous loops forms i

112 ical serial sections demonstrated that a new vascular network composed of venous-venous loops of vary

113 These vascular networks connect at the lymphovenous (LV) junct

114 essed in 14/21 eyes (67 %) and the branching vascular network decreased in 1 eye and was stable in al

115 Computer-assisted quantification of this vascular network demonstrated considerable sensitivity o

116 ow modelling and polarity analysis in entire vascular networks demonstrates that polarization against

117 Vascular network density determines the amount of oxygen

118 Blood vascular networks derived from implanted endothelial cel

119 Vascular networks develop from a growing vascular front

120 The process whereby the primitive vascular network develops into the mature vasculature, k

121 poietin-1 (Ang-1) stimulates endothelial and vascular network differentiation through the Tie-2 recep

122 phangiogenesis results in the formation of a vascular network distinct from arteries and veins that s

123 During this second stage, we assume that the vascular network does not evolve and is independent of t

124 d dynamic changes occurring to the lymphatic vascular network during TLS development have not been st

125 t roles in the establishment of neuronal and vascular networks during embryonic development.

126 eling are essential for the establishment of vascular networks during organogenesis.

127 nesis, nascent vascular sprouts fuse to form vascular networks, enabling efficient circulation.

128 ich has a large, transparent, extracorporeal vascular network encompassing an area >100 cm(2) We foun

129 choroidal telangiectases, abnormal choroidal vascular networks, exudative and hemorrhagic presentatio

130 zed to result from selection to maximize how vascular networks fill space yet minimize internal trans

131 The abnormal choroidal vascular network filled in the arterial or early venous

132 icrovascular endothelial cells (HMEC) showed vascular network formation after 48-72 h.

133 signaling, greater senescence, and impaired vascular network formation and proliferation.

134 e spinal cord, providing novel insights into vascular network formation around developing organs.

135 human microvascular endothelial cell (HMVEC) vascular network formation in a 3-dimensional collagen g

136 lated human umbilical vein endothelial cells vascular network formation in a matrigel assay.

137 esults provide a framework for understanding vascular network formation in normal or pathological con

138 affold, preconditioned MPCs greatly enhanced vascular network formation in the infarct bed by mechani

139 ntly compromised in their ability to support vascular network formation in vitro and in vivo.

140 with Robo4, and accelerates endothelial-cell vascular network formation in vitro with a specific acti

141 -delta inhibited cell motility and lymphatic vascular network formation in vitro.

142 New vascular network formation is a critical step in the wou

143 wed that TN-C is required for Prx1-dependent vascular network formation on Matrigel.

144 on of the fibroblasts was required to induce vascular network formation via a transforming growth fac

145 n regulating endothelial cell morphology and vascular network formation.

146 el roles for pericytes during the process of vascular network formation.

147 helial cell viability, and proliferation and vascular network formation.

148 n-B2, and stimulated VEGF responsiveness and vascular network formation.

149 The density and complexity of vascular networks formed by the synergistic dual-cell sy

150 These ECFC-lined vascular networks formed functional anastomoses with the

151 applied tensile forces on the morphology of vascular networks formed within fibroblast and endotheli

152 Vascular networks formed within HA hydrogels containing

153 ertebrates, including birds and mammals, the vascular network forms throughout the embryonic disk wit

154 logenesis, the de novo growth of the primary vascular network from initially dispersed endothelial ce

155 used trypsin digestion to isolate the intact vascular network from retinas obtained postmortem from n

156 ere were defects in formation of a primitive vascular network from SIRT1(-/-)-derived embryoid bodies

157 source of mesenchymal stem cells (MSCs).New vascular networks from undifferentiated cells are essent

158 extension and anastomosis are the basis for vascular network generation, a process governed by the V

159 entered on the idea that the geometry of the vascular network governs how a suite of organismal trait

160 cal columns that are tightly linked with the vascular network, graph-theoretical analyses revealed th

161 atiotemporal in silico replication of stable vascular network growth.

162 Endothelial cells of the periventricular vascular network have molecular identities distinct from

163 est acceptable grader agreement for the deep vascular network (ICC <0.85).

164 a in 33 eyes (69%) and an abnormal choroidal vascular network in 24 eyes (50%).

165 device platform with a microfluidics-modeled vascular network in a femoral arteriovenous shunt in rat

166 lant of the development and maintenance of a vascular network in embryogenesis and the vascularizatio

167 human endothelial cells formed a functional vascular network in immunocompromised mice with signific

168 wide range of tissue systems including fine vascular network in murine brain without craniotomy as w

169 To test this hypothesis, we evaluated the vascular network in spontaneously developing melanomas o

170 drives the formation of a robust and complex vascular network in the absence of exogenous growth fact

171 videnced a stage-dependent alteration of the vascular network in the cortices of fetuses with pFAS/FA

172 ALCAM(-/-) mice displayed an altered blood vascular network in the lung and the diaphragm, indicati

173 ascular precursor cells and that the primary vascular network in the retina develops by angiogenesis

174 51) mice, which lack ENS in the hindgut, the vascular network in this region appeared to be normal su

175 ve been investigated to include an organized vascular network in tissue constructs.

176 y detailed three-dimensional analysis of the vascular network in tumors.

177 es endogenous tissue dynamics to assembly of vascular networks in a mammalian system.

178 d quantitative analyses of three-dimensional vascular networks in all three models.

179 re, with reconstitution of rich intrainsular vascular networks in both species.

180 os showed a complete loss of high-complexity vascular networks in cotyledons and a drastic increase i

181 s can be a single source of odontoblasts and vascular networks in dental tissue engineering.

182 rongly support the use of human EPCs to form vascular networks in engineered organs and tissues.

183 ave focused on how stroke affects neural and vascular networks in experimental models of type 1 diabe

184 way required for separation of the two major vascular networks in mammals.

185 at neural activity promotes the formation of vascular networks in the early postnatal mouse barrel co

186 Blood vascular networks in vertebrates are essential to tissue

187 iate angiogenesis, and (iii) and intravasate vascular networks in vivo via a matrix metalloproteinase

188 ally resulted in the rapid regression of the vascular networks in vivo.

189 ferative and vasculogenic activity to create vascular networks in vivo.

190 red as a distinct area of hyperfluorescence (vascular network) in early to intermediate frames and as

191 of the major vessels of the trunk lymphatic vascular network, including the later-developing collate

192 s with the host circulation is essential for vascular networks incorporated within cell-seeded bioeng

193 rmine the distribution of oxygen in a native vascular network, incorporating into our model features

194 We found that the enteric and vascular networks initially had very distinct patterns o

195 Yet the mechanism by which implanted vascular networks inosculate, or anastomose, with the ho

196 by pericytes and a role for gap junctions in vascular network interactions.

197 Assembly of these vascular networks involves sprouting, migration and prol

198 The microfluidics-based vascular network is a promising platform for generating

199 As it is altered by ionizing radiation, the vascular network is considered as a prime target in limi

200 well as appropriate localization of the deep vascular network is mediated by R-cadherin, an adhesion

201 enhances ischemia-induced remodeling of the vascular network is not known.

202 Establishment of a functional vascular network is rate-limiting in embryonic developme

203 onstrate that the expansion of the lymphatic vascular network is tightly regulated.

204 on and maintenance of blood flow through new vascular networks is essential for successfully treating

205 h to adulthood, but the normal patterning of vascular networks is maintained.

206 Angiogenesis, the growth and remodeling of a vascular network, is an essential process during develop

207 cyte coverage and formation of dense retinal vascular networks lacking the normal hierarchical arrang

208 nsity evident by CD31 staining as well as in vascular networks layered with smooth muscle cells when

209 signaling in the maturation of the lymphatic vascular network likely via regulating the perivascular

210 e morphology and location of BMCs within the vascular network may be observed along with differentiat

211 Assessing FAZ alterations in the deep vascular network may be subject to greater interobserver

212 Our results demonstrate that vascular network models cannot ignore certain complexiti

213 At the level of vascular network morphology, 7 months' diabetes induced

214 In addition, the vascular network must be organized so that all the paren

215 ng the primary tumor from developing its own vascular network needed for further growth.

216 monstrated that for insufficiently developed vascular networks, NPs are transported preferentially th

217 ent, the formation and remodeling of primary vascular networks occurs by vasculogenesis and angiogene

218 By using the vascular network of EMBs, EMBs can be perfused ex vivo a

219 methods that allow examination of the intact vascular network of large organs, such as the human plac

220 apted to exert their immune functions in the vascular network of the liver.

221 During mouse development, the sophisticated vascular network of the lung is established from embryon

222 the stepwise assembly and patterning of the vascular network of the zebrafish hindbrain.

223 A-4-phosphate (CA-4-P), rapidly disrupts the vascular network of tumors leading to secondary tumor ce

224 ansformed cells acquired the ability to form vascular networks on Matrigel.

225 t explanations focus on predicting the whole vascular network or sprout from the underlying cell beha

226 Our aim was to elucidate alterations of the vascular network organization, taking advantage of Flk1(

227 omography angiography provided more distinct vascular network patterns that were less obscured by sub

228 eed (74 mm/s) navigation of a multi-branched vascular network phantom.

229 Square-spiral towers, isolated within this vascular network, promote fluid mixing through chaotic a

230 Understanding the forces controlling vascular network properties and morphology can enhance i

231 Vascular network quantification by using high-spatial-re

232 The OCTA clearly identified vascular network rarefaction with decreased choriocapill

233 ndothelial cells to organize themselves into vascular networks, rather than from defects in tissue-sp

234 lishing the anatomical form of the lymphatic vascular network remain largely unknown.

235 Importantly, the engineered vascular networks remained patent at 4 weeks in vivo.

236 These results indicated that the yolk sac vascular network remains a site of progenitor production

237 This induces a vascular network remodeling response in the healing ovar

238 for macrophages in supporting the extensive vascular network required for corpus luteum integrity an

239 of new capillary sprouts from a preexisting vascular network requires a highly coordinated cellular

240 Morphogenesis of the developing vascular network requires coordinated regulation of an e

241 Morphogenesis of a vascular network requires dynamic vessel growth and regr

242 ary and sufficient to trigger alterations of vascular networks reveals an important feature of neurov

243 are central determinants in the formation of vascular networks seen in vertebrate organisms.

244 The differences between vascular networks, sexes, and fellow eyes and correlatio

245 A comparison with the plant vascular networks shows that the same optimization crite

246 Simulations differing only in initial vascular network structures but with identical dynamics

247 cientists have long sought to understand how vascular networks supply blood and oxygen to cells throu

248 Vascular networks surrounding individual organs are impo

249 These engineered human vascular networks survive implantation, integrate with t

250 arts that exhibited an elaborate ventricular vascular network, Tbx5(epi-/-) hearts displayed a marked

251 These tumors also showed a more developed vascular network than control tumors and secreted elevat

252 As a result, an organized vascular network that is optimal for tissue perfusion is

253 characterized by an aggressive and aberrant vascular network that promotes tumor progression and hin

254 arises from a preexisting red cell-deficient vascular network that remodels to patency to accommodate

255 n and fabricate a liver-assist device with a vascular network that supports a hepatic parenchymal com

256 t uterus and the development of an elaborate vascular network that supports embryonic growth.

257 largely responsible for maintaining the fine vascular network that surrounds highly remodeling bone.

258 of the peri-neural vascular plexus (PNVP), a vascular network that surrounds the CNS and is critical

259 generate an extensive primitive plexus-like vascular network that would perfuse the entire scaffold

260 owth requires the development of independent vascular networks that are often primitive in morphology

261 ricyte-induced stabilization of newly formed vascular networks that are predisposed to undergo regres

262 is comprised of two parallel, yet distinct, vascular networks that carry blood to and from the heart

263 Angiogenesis produces primitive vascular networks that need pruning to yield hierarchica

264 d alone in vivo, they formed transient blood vascular networks that regressed by day 30.

265 uced the formation of dilated and normalized vascular networks that were hypersensitive to anti-VEGF

266 In the absence of perfusable vascular networks, three-dimensional (3D) engineered tis

267 ions with the LVV to safeguard the lymphatic vascular network throughout life.

268 hat considers the average conductance of the vascular network to a representative areole (region boun

269 or cartilage, and the re-establishment of a vascular network to maintain cell viability.

270 y achieved because of the confinement of the vascular network to one plane close to the surface of th

271 Engineered tissues need a vascular network to supply cells with nutrients and oxyg

272 P1 expression from the mature regions of the vascular network to the growing vascular front was obser

273 of water under tension, but also exposed the vascular network to the risk of gas emboli and the sprea

274 in perfusion and function: the patterning of vascular networks to efficiently deliver blood and nutri

275 equire high rates of perfusion by functional vascular networks to ensure proper sensory transmission.

276 cells and promotes the formation of abnormal vascular networks typical of KS vasculature; upregulates

277 nsport was simulated for a three-dimensional vascular network using parameters for rat extensor digit

278 gineering will rely on our ability to create vascular networks using human cells that can be obtained

279 The decellularized vascular network was able to withstand fluid flow that e

280 "margin," and "location," either because the vascular network was not clearly shown (3 cases) or beca

281 In addition, a branching vascular network was noted above the Bruch membrane in 1

282 The vascular network was used to reseed the scaffolds with h

283 map of all endothelial cells in a remodeling vascular network, we propose that balanced movement of c

284 nt of the right-hand side and left-hand side vascular networks well before the network asymmetry beco

285 face angiograms of the superficial and deep vascular networks were acquired.

286 Vascular networks were derived from the reconstruction.

287 stricted, fewer small vessels were seen, and vascular networks were disorganized.

288 cxcr4a mutant zebrafish fail to form a vascular network, whereas ectopic expression of Cxcl12b

289 rs undergo vigorous growth and remodeling of vascular networks, which results in disappearance of the

290 y of aggressive cancer cells forming de novo vascular networks, which thereby contribute to perfusion

291 of-function causes formation of a hyperdense vascular network with disturbed blood flow.

292 Fli1 CKO mice showed a disorganized dermal vascular network with greatly compromised vessel integri

293 hat needs to be reorganized into a secondary vascular network with higher hierarchical structure.

294 somotor activity along a genetically defined vascular network with pharmacological and immunohistoche

295 is was confirmed by the presence of tortuous vascular networks with high levels of expression of CD31

296 bioengineering is the need for a functional vascular network within the engineered tissue.

297 muscle cells that surround and constrain the vascular network within the glomerulus of the kidney.

298 ased approach to generate endothelialized 3D vascular networks within cell-laden hydrogel biomaterial

299 ion of cancer is dependent on acquisition of vascular networks within the tumor.

300 ows for the evaluation of functional retinal vascular networks without a need for contrast dyes.