ライフサイエンスコーパス: vascularity

1 nce useful in the assessment of brain tumors vascularity.

2 in the process of evaluation of intratumoral vascularity.

3 cells and was associated with reduced tumor vascularity.

4 evidence of neuronal recovery with increased vascularity.

5 eated mice, correlating with decreased tumor vascularity.

6 ncreased proliferation, tumor outgrowth, and vascularity.

7 r mucosal wounds, nor did it alter wound bed vascularity.

8 ha expression and marked inhibition of tumor vascularity.

9 ta cells, in the absence of changes in islet vascularity.

10 fects on ECM remodeling and increased muscle vascularity.

11 odels, concomitant with an increase in tumor vascularity.

12 xpression of IL-17 in mouse ankles increases vascularity.

13 lved in tumor-stromal interactions and tumor vascularity.

14 ewer endothelial cells indicative of reduced vascularity.

15 luences endothelial cell migration and tumor vascularity.

16 ion reduced pericytes without reducing tumor vascularity.

17 microvessel density and other indicators of vascularity.

18 severity and more prominent inflammation and vascularity.

19 sessment of intratendinous and peritendinous vascularity.

20 nd diabetes reversal, due to hypoxia and low vascularity.

21 kles and the IPE cyst did not have intrinsic vascularity.

22 bility of WT HSV to increase infected tissue vascularity.

23 pressing prostate growth by targeting tissue vascularity.

24 nically exposed to hypoxia owing to aberrant vascularity.

25 ound healing was notable for increased wound vascularity.

26 stered locally did not alter tumor growth or vascularity.

27 mor, delay of tumor growth, and intratumoral vascularity.

28 s were also immunostained for CD31 to assess vascularity.

29 achment of pericytes and disruption of tumor vascularity.

30 nt status, or histologic assessment of tumor vascularity.

31 , histological analysis, and quantitation of vascularity.

32 hen MVD may not accurately reflect a tumor's vascularity.

33 -enhanced US improves visualization of tumor vascularity.

34 eceptor knockout mice reflecting the reduced vascularity.

35 ents, the lesions were hyperechoic with poor vascularity.

36 vascular structures and quantify intestinal vascularity.

37 erage of tumors, depending on their size and vascularity.

38 pair, irrespective of fracture stability and vascularity.

39 ing iris melanocytic lesions, for growth and vascularity.

40 patterning that results in high interdigital vascularity.

41 s-like enhancement associated with increased vascularity.

42 0.1) for bleb height, and 3.4 (0.2) for bleb vascularity.

43 animal to detect mural inflammation or tumor vascularity.

44 pt and survive long-term reductions in islet vascularity.

45 The treated group also revealed less vascularity (1.6 +/- 0.1 units vs. 1.1 +/- 0.0 units; P

46 s in granuloma formation (30%) and granuloma vascularity (42%) in a murine chronic inflammation-induc

47 led that the tumors have evidence of reduced vascularity after treatment.

48 parenchyma and lesion signal intensities and vascularity, airway, esophagus, and diaphragm appearance

49 onfirmed a significant increase in lymphatic vascularity, along with reversal of the intense tissue h

50 specifically into BAT of obese mice restored vascularity, ameliorated brown adipocyte dysfunction, an

51 F and PDGF inhibition together reduced tumor vascularity and abundance of pericytes.

52 ut the change was less than the reduction in vascularity and actually increased when expressed per su

53 reproducible technique for quantifying tumor vascularity and angiogenesis in advanced HCC.

54 period ameliorates inflammation and restores vascularity and beta-cell function into adulthood, demon

55 1 in animals with an established neuropathy, vascularity and blood flow returned to levels similar to

56 proteins involved in regulating white matter vascularity and blood flow.

57 The increased vascularity and bone regeneration in the pVHL mutants we

58 Cell implantation markedly improved vascularity and cardiac function after myocardial infarc

59 ged mice also demonstrated higher ratios for vascularity and cellularity of the CNV (1.34 +/- 0.06 vs

60 rmacologic induction of bradycardia enhances vascularity and coronary reserve, preserves function of

61 lthough some markers of tumor growth such as vascularity and cyclin D1 expression are suppressed, pri

62 is sometmies impossible because of the rich vascularity and difficult location.

63 If the vascularity and echogenicity of the scrotal mass is simi

64 cs of tissue that surrounds tumor, including vascularity and electric conductivity, affect ablation o

65 e depends on the stage of tumor development (vascularity and endothelial receptor expression) and the

66 retrospective studies was to evaluate tumor vascularity and expression of components of the VEGF pat

67 umour cell implantation, with reduced tumour vascularity and extensive necrosis.

68 maging, additional tissue properties such as vascularity and fibrosis can be demonstrated.

69 on, treatment with bevacizumab reduces tumor vascularity and growth.

70 it results in a permanent reduction in islet vascularity and impaired insulin secretion.

71 nd endothelial cells, resulting in increased vascularity and improved cardiac function.

72 enchymal-to-endothelial transition, enhances vascularity and improves cardiac function.

73 are malignant tumors characterized by their vascularity and invasive capabilities.

74 erative and apoptotic activities, as well as vascularity and macrophage infiltration that correlated

75 olesions' together with a global increase in vascularity and microglia.

76 Vascularity and myeloid suppressor cell populations and

77 romotes progression through effects on tumor vascularity and myeloid suppressor cell populations, in

78 Increased vascularity and neoangiogenesis have been implicated in

79 e was associated with enhanced intralesional vascularity and neutrophilic inflammation, which are hal

80 effects of glucose and inflammation on islet vascularity and on beta function, mass, and insulin in i

81 entify Vegfa as a regulator of perichondrial vascularity and osteoblast differentiation at early stag

82 rine growth restriction (IUGR) on pancreatic vascularity and paracrine signaling between the EC and b

83 rectal cancer can enable assessment of tumor vascularity and perfusion changes that result from chemo

84 y period results in augmentation of lesional vascularity and perfusion, as well as improved motor rec

85 st cancer appears to predict increased tumor vascularity and perhaps cancer dissemination by hematoge

86 re the biologic effects of the drug on tumor vascularity and permeability.

87 y be related to factors altering endometrial vascularity and permeability.

88 vation in osteoblasts had markedly increased vascularity and produced more bone in response to distra

89 relationships between anaplasia, tumor size, vascularity and prognosis, and local recurrence seeded b

90 Preserved vascularity and reduced inflammation correlated with imp

91 iority in an order reflecting superiority of vascularity and resistance to radiation: latissimus dors

92 AMG 386 also appeared to impact tumor vascularity and showed antitumor activity in this patien

93 significantly increased cell proliferation, vascularity and synaptogenesis, as well as reduced apopt

94 d regression that are respectively linked to vascularity and tumor cell alterations, including cellul

95 s the VEGF blocker aflibercept reduced tumor vascularity and tumor perfusion more dramatically than e

96 In addition to angiographic data on vascularity and vascular access, demonstration of hepato

97 inclusion of vascular factors such as tumor vascularity and vascular involvement, ulceration was no

98 a and is associated with increased bronchial vascularity and vascular permeability.

99 lating VEGF-A expression may influence islet vascularity and, consequently, the amount of insulin del

100 ession may be a means to regulate lymph node vascularity and, potentially, immune function.

101 creas showed increase in cell proliferation, vascularity, and abnormal vascular structures; such chan

102 stroma have a differentiated phenotype, low vascularity, and are associated with a favorable prognos

103 hemoglobin levels, suggesting reduced joint vascularity, and both endothelial cell migration and tub

104 for flatmount analysis of CNV surface area, vascularity, and cellularity.

105 Flap angiography confirmed intact vascularity, and computer tomography scan and histology

106 eatment led to delayed tumor growth, reduced vascularity, and decreased lung metastasis.

107 ations in lipid regulatory factors, enhanced vascularity, and decreased M1/M2 macrophage ratios may a

108 nts may decrease tumor contrast-enhancement, vascularity, and edema, the mechanisms leading to improv

109 irway smooth muscle (ASM), mucus gland area, vascularity, and epithelial integrity.

110 es were evaluated for tumor size, pattern of vascularity, and extent of vascularity (vascularity inde

111 TNFalpha-associated tumor growth, vascularity, and generation of tumor vascular leukocytes

112 their ability to inhibit tumor angiogenesis, vascularity, and growth.

113 ibited undifferentiated histology, increased vascularity, and heightened proliferation--features that

114 en I deposition, decreased cellularity, less vascularity, and higher glycosaminoglycan content when c

115 Granulation tissue area, vascularity, and IGF1 and EGF receptor phosphorylation a

116 pitulates tumor heterogeneity, invasiveness, vascularity, and immunosuppressive microenvironment in s

117 he overall size of claustrum, its pronounced vascularity, and its more complex intrinsic connectivity

118 proliferation, increased fibrosis, increased vascularity, and mast cell infiltration.

119 s measured that related to tumor blood flow, vascularity, and oxygenation demonstrated no significant

120 owth, numbers of metastases to major organs, vascularity, and perfusion between SU5416-treated and co

121 oved scarring in terms of height, thickness, vascularity, and pigmentation (12 months and 18-24 month

122 ingival tissue eases manipulation, maintains vascularity, and promotes wound healing during and after

123 translucent structure, granularity, fibrin, vascularity, and stool after oral or rectal allergen cha

124 ranslucency, granularity, fibrin production, vascularity, and stool.

125 ce of a capsule, homogeneity, the pattern of vascularity, and washout.

126 , in human prostate cancer cells and reduced vascularity (angiogenesis) in vivo using Matrigel plug a

127 Ageing reduced vascularity ( approximately 50%, P < 0.01), angiogenic c

128 onments associated with inflammation or poor vascularity are encountered in vivo.

129 way smooth muscle, extracellular matrix, and vascularity are prominent features of airway remodeling

130 CAM treated with EMD displayed moderate vascularity as indicated by a maximal score of 3.0 +/- 0

131 ), as was the total color Doppler area (CDA; vascularity assessment) (median reduction 100% and 47.1%

132 ockade resulted in markedly increased tumour vascularity, associated with enhanced angiogenic sprouti

133 and changes in synovial thickening and joint vascularity at 18 weeks, we were able to distinguish tho

134 phic measurements of synovial thickening and vascularity at baseline in the placebo + MTX group demon

135 of microerosions (P < .0001), and increased vascularity at the squamocolumnar junction (OR, 9.3; 95%

136 ibomian gland quality, orifice plugging, lid vascularity) between patients with PTSD or depression an

137 ssociated with a prominent decrease in tumor vascularity (blood and lymph vessels), likely due to red

138 e transfer exhibited significantly decreased vascularity both in an orthotopic and in an ectopic mode

139 ling can block angiogenesis and reduce tumor vascularity, but little is known about the reversibility

140 hibitor of VEGF signaling, reduced the tumor vascularity by 86%.

141 erazine, non-invasive visualization of tumor vascularity by bioluminescence imaging was possible.

142 During painful crisis, a further decrease in vascularity (caused by flow stoppage in small vessels) a

143 biology by probing characteristics of tumour vascularity, cellularity and metabolism which critically

144 Tumor vascularity changes during treatment were assessed from

145 collagen alignment and an advanced state of vascularity compared to control treatments.

146 C chemokines (ie, the ELR score) and greater vascularity compared with tumors in which MIF-CD74 co-ex

147 Early differences in vascularity correlated with later bone development.

148 nsgenic mice, where pericytes decreased 47%, vascularity decreased 38%, and basement membrane sleeves

149 Overall tumor vascularity decreased 79% over 28 days, without a corres

150 he hypothesis that abnormal gastrointestinal vascularity develops during continuous-flow LVAD support

151 Intratumoral vascularity did not correlate with either tumor size or

152 However, histologic patterns of tumor vascularity do not correlate with Doppler US depiction o

153 n following POH, while preserving myocardial vascularity, does not prevent mitochondrial and contract

154 +) will improve histological measurements of vascularity, fibrosis, and inflammation in human subject

155 ing CNR and providing increased perilesional vascularity, Gadovist can help in the determination of m

156 Plaque vascularity has been implicated in its growth and stabil

157 or receptor (EGFR) associated with increased vascularity has been implicated in the pathogenesis of F

158 issue, and glandular tissue contains greater vascularity, hence, more total hemoglobin.

159 tivation was associated with decreased islet vascularity, highlighting the proposed role of endotheli

160 y with RTKIs abrogated the increase in islet vascularity, impairing T-cell migration into the islet a

161 maging depicted an absence of residual nidus vascularity in 32 (76%) of the 42 patients who were trea

162 ranulation tissue reconstitution, and tissue vascularity in a murine model of repair stimulation.

163 ation of FLLL32 can inhibit tumor growth and vascularity in chicken embryo xenografts as well as subs

164 m of this study was to evaluate interstitial vascularity in cryptogenic fibrosing alveolitis (CFA) an

165 ffered due to reduced central and peripheral vascularity in MMC group (P = 0.027; P = 0.041).

166 T whitening, supporting a role for decreased vascularity in obesity-associated BAT.

167 method for longitudinal monitoring of tumor vascularity in response to the anti-angiogenic drug tivo

168 By contrast, there was only mild vascularity in sections treated with the negative contro

169 enable the in-vivo visualization of abnormal vascularity in synovium and subchondral bone that have n

170 after 4 days and a 2.8-fold increase in the vascularity in the dermis that peaked after 2 days.

171 nified layer (hyperkeratosis), and increased vascularity in the dermis.

172 However, the role of tumor vascularity in the prognostic assessment of melanoma rem

173 ional liver tissue is limited by the lack of vascularity in the tissue-engineered constructs.

174 ficant suppression of tumor growth and tumor vascularity in vivo by targeting Akt and focal adhesion

175 Vascularity in whole knees and distal femora was signifi

176 In 2 eyes with nevi there was no increased vascularity; in another, fine vascular loops were noted

177 Changes in tumor size, pigmentation, and vascularity; incidence of iris neovascularization; and r

178 Rosuvastatin restored nerve vascularity, including vessel size, and nerve function a

179 prominent increase in CNR, and perilesional vascularity increase are important findings determining

180 increase in CNR, and absence of perilesional vascularity increase support findings of benign breast l

181 By contrast, 10% O2 impaired fetal vascularity, increased barrier thickness and reduced pla

182 Tumors had decreased volumes, decreased vascularity, increased CTL infiltrate, and Nrp1-depleted

183 cination of tumor-bearing mice reduced tumor vascularity, increased infiltration of CD3+ T cells into

184 hytherapy included decreased intrinsic tumor vascularity, increased tumor pigmentation, and decreased

185 found between the pattern of vascularity or vascularity index before or after contrast material admi

186 n of vascularity, and extent of vascularity (vascularity index).

187 The tissue samples were analyzed for vascularity, inflammatory cell infiltration, growth patt

188 ized by large areas of apoptosis, diminished vascularity, inhibition of hyperplasia in overlying epid

189 r solid tumors and metastatic lesions, tumor vascularity is a critical factor in assessing response t

190 Nonischemic muscle vascularity is also lower in Y2(-/-) mice, whereas it is

191 Increasing tumor vascularity is highly correlated with ulceration, possib

192 quence of PDGF-B blockade, but reduced tumor vascularity is likely to be secondary to pericyte regres

193 In infected tumors, this increased vascularity is mediated by reduced TSP-1 and TSP-2 level

194 ther this ability to enhance infected tissue vascularity is retained in oncolytic HSV, which could be

195 This increased vascularity lacked functionality, correlating with enhan

196 , vasoconstriction and altered expression of vascularity markers in skin and internal organs, early i

197 Quantitative Doppler US vascularity measurements considerably contribute to mali

198 gist-defined ellipsoid, in which six Doppler vascularity measures were calculated.

199 lioblastoma, including tumor cellularity and vascularity, metabolite expression, and patterns of tumo

200 For intrinsic vascularity (n = 19), 12 tumors (63%) showed decrease an

201 Permanent reductions in placental vascularity occurred during the earlier but not the late

202 aphic (CT) perfusion for evaluation of tumor vascularity of advanced hepatocellular carcinoma (HCC) a

203 dministration resulted in increased size and vascularity of CNV, and older mice developed a greater r

204 CL(2)MDP-lip reduces size, cellularity, and vascularity of CNV.

205 Perfusion CT measurements may measure vascularity of colorectal tumors, however, correlation w

206 tumor sections revealed 70 to 80% diminished vascularity of HAS antisense tumors.

207 ma4D shRNA reduces dramatically the size and vascularity of HNSCC tumor xenografts.

208 ro endothelial cell migration and growth and vascularity of HNSCC xenografts expressing a degradation

209 xamination of two cases showed intralesional vascularity of mild-to-moderate degree.

210 Size and vascularity of MNV imaged with OCTA before and after the

211 NFalpha expression promoted tumor growth and vascularity of mouse melanoma, lung cancer, and mammary

212 mice with XL999 resulted in 43% reduction in vascularity of spontaneous pancreatic islet tumors over

213 m the avascularity of thrombi and the sparse vascularity of stromal tumors.

214 The enhanced vascularity of the -/- tumors is particularly significan

215 The vascularity of the 5-kDa EMD-protein fraction was not di

216 pothesized that this is related to the local vascularity of the bone.

217 of 7.5-10 MHz to observe the morphology and vascularity of the eyeball was applied.

218 om the OCTA images, we assessed the size and vascularity of the MNV.

219 derstanding may help clinicians optimize the vascularity of the recipient bed to further improve fat

220 marrow transplantation models, the enhanced vascularity of the wound was shown to be mediated, at le

221 ger of the angiogenic switch, increasing the vascularity of tumors and inducing molecular markers of

222 rowth factor (VEGF) signaling can reduce the vascularity of tumors and leakiness of surviving vessels

223 pact of increased PHIP copy number and tumor vascularity on ulceration status was highly significant

224 correlation was found between the pattern of vascularity or vascularity index before or after contras

225 d not affect tumor proliferation, apoptosis, vascularity, or lymphocyte infiltration.

226 the number of reported adverse events, bleb vascularity, or morphology between the 2 groups.

227 .021), and gross appearance of intratumoral vascularity (P = .018).

228 scribed oval mass (P = .024) at mammography, vascularity (P = .047) and posterior enhancement (P = .0

229 > .999), ectropion (P > .999), and intrinsic vascularity (P = .70).

230 3 times less ischemia and greater peripheral vascularity (P = 0.001) than control animals treated wit

231 d that ligands for CRFR2 act to limit tissue vascularity, perhaps as a counterbalance to factors that

232 ealing wounds as controls, and the increased vascularity persisted for at least 2 weeks.

233 lar keratitis, by increasing infected tissue vascularity, possibly reflecting altered angiogenic fact

234 nopposed action of Ang1, but decreases tumor vascularity primarily by blocking Ang2 actions.

235 The decrease in vascularity produced by SelCID treatment is attributed t

236 ormalization, but not the reduction in tumor vascularity produced by the Ang2 inhibitor.

237 tion of signaling pathways that govern tumor vascularity provide a potential avenue to thwart cancer

238 , no Doppler feature, including intranodular vascularity, pulsatility index, resistive index, or peak

239 rrelated significantly with histologic tumor vascularity (r = 0.83; P < 0.001).

240 l tumors attached to peritoneal organs, with vascularity ranging from 2% to 10%, also show enhanced d

241 Tumour growth was retarded and vascularity reduced in clec14a(-/-) mice.

242 reased circulating EPC counts and myocardial vascularity, reduced fibrosis, and improved cardiac func

243 e genetic program with increased scar border vascularity, reduced fibrosis, and recovery of pumping f

244 Features that were evaluated included lesion vascularity relative to the adjacent cortex in the arter

245 surface area (in relative disc areas or DA), vascularity (relative fluorescence), and cellularity (pr

246 tial for direct nose to brain delivery, high vascularity, relatively large absorptive surface area, a

247 er differences observed in RBM thickness and vascularity result from disease or normal age-related de

248 Tumor vascularity seems to be a precursor of both vascular inv

249 Increasing tumor vascularity significantly increased the risk of relapse

250 Interestingly, adventitial vascularity significantly increased, suggesting a mechan

251 the immunohistochemical assessment of tumor vascularity (SMA and CD34 counts) (P < .003).

252 ovides dynamic real-time assessment of tumor vascularity so that contrast enhancement can be identifi

253 This compared favorably to the degree of vascularity stimulated by the mixture of fibroblast grow

254 f the synovium, its thickening and increased vascularity through ultrasound and magnetic resonance ex

255 e developed a novel approach to assess tumor vascularity using recombinant Gaussia luciferase (rGluc)

256 size, pattern of vascularity, and extent of vascularity (vascularity index).

257 addition to improving lymphatic function and vascularity, VEGF-C can apparently reverse the abnormali

258 hin the hydrogels and significantly improved vascularity, ventricular geometry, ejection fraction, ca

259 ith vascular involvement and increased tumor vascularity versus matched controls lacking these factor

260 Immunohistochemistry was employed to measure vascularity (vWF), neurogenesis (BrdU TUJ1, DCX and NeuN

261 relationship between stromal Sdc1 and tumor vascularity was also examined in a tissue array containi

262 The fact that vascularity was also increased by recombinant human amel

263 Vascularity was also increased by recombinant human amel

264 Subchondral bone plate vascularity was altered with increasing stages of OA.

265 Tumor vascularity was assessed from total Hb (tHb), oxygenated

266 Increasing tumor vascularity was associated with increased incidence of u

267 Similarly, vascularity was consistently lower in the tumor center c

268 Bleb vascularity was graded on a scale of 1 to 5 (1 indicatin

269 d to control eyes with emmetropia, choroidal vascularity was greater in eyes with high myopia (beta =

270 Vascularity was higher in group 1 than in group 2 (P = 0

271 Lung vascularity was increased by MFN2.

272 d fibrosarcomas was impaired, although tumor vascularity was increased.

273 Paradoxically, this increased vascularity was non-productive-as shown by poor perfusio

274 On color Doppler US, no vascularity was observed in the heterogeneous testicular

275 Vascularity was present in all lesions (n = 94) at contr

276 At the higher amounts, vascularity was reduced and not significantly different

277 number of sprouts was reduced by 82%, tumor vascularity was reduced by 67%, and tumor growth slowed

278 Histologic analysis revealed that vascularity was reduced in sEphB4-treated membranes.

279 Intestinal vascularity was significantly higher after LVAD support

280 Change in wound bed vascularity was significantly lower in oral wounds than

281 ailed to penetrate grafts, and after 2 weeks vascularity was still disturbed.

282 Using the Power Doppler callus vascularity was visualized and vascular resistance index

283 Tumor permeability and vascularity were assessed by calculating the bidirection

284 Nevertheless, muscle insulin action and vascularity were increased.

285 ize used in these studies, no differences in vascularity were observed, and MR parameters measured th

286 orescence imaging, alterations in knee joint vascularity were quantified with muCT after perfusion of

287 the newborn neovasculature as well as tissue vascularity were significantly increased by coadminister

288 ous, homogenous), and perilesional increased vascularity were studied.

289 ate analysis, vascular involvement and tumor vascularity were the strongest predictors of melanoma ou

290 blood perfusion, cellular proliferation, and vascularity were visualized using Hoechst 33342, bromode

291 s correlated with the normalization of tumor vascularity when injected during tumor growth and with t

292 elling of specific CSPGs as well as enhanced vascularity, which was closely associated with CD206-pos

293 ) and foveal (1.5 mm) regions, and choroidal vascularity, which was determined by dividing vascular a

294 ealed that VEGFR-2 was confined to the islet vascularity, which was increased in inflamed islets.

295 or's environment (eg, stromal matrix, tissue vascularity),will likely enable improved treatment strat

296 ssociated increase in mesenteric and colonic vascularity with an increase in mean signal intensity of

297 ssociated increase in mesenteric and colonic vascularity with an increase in mean signal intensity of

298 t in the angiogenic balance toward increased vascularity with reduced tumor cell apoptosis.

299 onfiguration, lesion pigmentation, intrinsic vascularity within the lesion, presence of associated pi

300 However, VEGF inhibition reduced tumor vascularity without decreasing pericyte density, and PDG