ライフサイエンスコーパス: vascularization

1 fusion limitations and facilitating adequate vascularization.

2 s to overcome the effects of hypoxia or poor vascularization.

3 impaired wound closure and compromised wound vascularization.

4 an promote angiogenesis, which improves bone vascularization.

5 roperties, mitigation of host responses, and vascularization.

6 ed improved wound closure and improved wound vascularization.

7 ked reductions in hyperplasia, dysplasia and vascularization.

8 bone grafting is the lack of sufficient bone vascularization.

9 angiogenesis in both physiological and tumor vascularization.

10 ice led to diminished SK lesions and corneal vascularization.

11 nt of mucogingival defects by inducing local vascularization.

12 that facilitates rapid restoration of islet vascularization.

13 ch are derived from vascular initials during vascularization.

14 g to excessive cellular consumption and poor vascularization.

15 tumor microenvironment because of inadequate vascularization.

16 ly induced tumors that also display enhanced vascularization.

17 size reduction and a 90% reduction in tumor vascularization.

18 ber of regulatory T cells and limiting tumor vascularization.

19 eceptor essential for angiogenesis and tumor vascularization.

20 tages of chondrogenesis, including transient vascularization.

21 tinal neurons titrate VEGF to limit neuronal vascularization.

22 t strategy to improve EC transplantation and vascularization.

23 e in the face of stressors due to inadequate vascularization.

24 ing cells can enhance the potency of EVs for vascularization.

25 nto the cornea and results in its subsequent vascularization.

26 ndothelial cells and reduced neonatal retina vascularization.

27 ed intratumoral expression of VEGF and tumor vascularization.

28 ulogenesis during both development and tumor vascularization.

29 lecular environment needed for normal thymic vascularization.

30 ion of nutrients and oxygen and induce tumor vascularization.

31 uced labyrinth surface area and blood vessel vascularization.

32 ccelerated tumorigenesis while also altering vascularization.

33 ce, and tumors were evaluated for growth and vascularization.

34 action but exhibited fibrosis, and GS showed vascularization.

35 ing, corneal neovascularization, and retinal vascularization.

36 d supply of oxygen caused by a lack of early vascularization.

37 critical factor in the development of islet vascularization.

38 is not effective for CSBDs due to inadequate vascularization.

39 C-associated protein, promotes breast cancer vascularization.

40 k rarefaction with decreased choriocapillary vascularization.

41 of CAFs to deform the matrix and suppressed vascularization.

42 se, which was a feature of module-associated vascularization.

43 rmed to determine the absence or presence of vascularization.

44 e channels, which we termed primitive myxoid vascularization.

45 ally-inhibited CAFs showed partial rescue of vascularization.

46 nation in human GBM, despite increased tumor vascularization.

47 e brain increases HIF-1alpha/VEGF levels and vascularization.

48 in vitro and in vivo and inhibited xenograft vascularization.

49 on and tumor cell killing, and altered tumor vascularization.

50 , and a link between T cell infiltration and vascularization.

51 of biochemical events related to healing and vascularization.

52 ture system as a platform for studying tumor vascularization.

53 plex interplay between hormone secretion and vascularization.

54 ovasculature, resulting in an improved early vascularization.

55 issue formation and remodeling, and to tumor vascularization.

56 cers (2), graft infection (2), and interface vascularization (4).

57 h malignant tumors [P < .001]), and internal vascularization (70 of 86 patients with tumors vs seven

58 e recurrence brought upon in-part by delayed vascularization accompanied by overactive inflammatory r

59 lop a safe and effective therapy for corneal vascularization, adeno-associated virus (AAV) gene thera

60 ients of oxygen/nutrients due to inefficient vascularization and abundant stroma, and thus is able to

61 splayed greater MDSC infiltration, increased vascularization and accelerated tumor growth.

62 prostate cancer models, each with different vascularization and acid-extruding protein carbonic anhy

63 is sufficient to cause regression of tumour vascularization and an enhanced immune response, leading

64 ctivated macrophages in turn promote stromal vascularization and angiogenesis even before the formati

65 into engineering approaches for therapeutic vascularization and angiogenesis, whether by creating ne

66 ing it an ideal monocot model for addressing vascularization and biomass deposition.

67 of RAD001 was associated with reduced tumor vascularization and cell proliferation but occurred inde

68 thelial cell (EC) plasticity drives aberrant vascularization and chemoresistance in glioblastoma mult

69 occurred in 44% (11/25; P = 0.001), corneal vascularization and conjunctivalization in 24% (6/25; P

70 hat had to be removed after 2 years owing to vascularization and corneal thinning.

71 a reveal that Egfl7 is crucial for placental vascularization and embryonic growth, and may provide in

72 st formation and permitting normal placental vascularization and embryonic growth.

73 ecific deletion of YAP/TAZ leads to impaired vascularization and embryonic lethality.

74 he platform circumvented the need for tissue vascularization and enabled higher-throughput image-base

75 Possibilities of integrating vascularization and encapsulation in bioprinted tissues

76 tissue engineering are restricted by delayed vascularization and fail to recapitulate this stepwise d

77 other transcription factors associated with vascularization and fiber formation and components of ce

78 ; non-CM-specific miRNAs regulate myocardial vascularization and fibrosis.

79 ls plays a pivotal role in maintaining islet vascularization and function.

80 pe (wt) pigs were used to analyze myocardial vascularization and function.

81 s and morphology can enhance in vitro tissue vascularization and graft integration prospects.

82 een reported to critically account for tumor vascularization and growth in mouse tumor experimental m

83 ablation of sprouting ECs diminished tumour vascularization and growth without compromising vascular

84 ation of PlGF-2/Neuropilin-1-mediated tissue vascularization and growth.

85 , which may contribute to an impaired lesion vascularization and growth.

86 c effect likely as a result of earlier islet vascularization and improved islet engraftment.

87 procedure to investigate bone regeneration, vascularization and infection prevention in response to

88 LA-G to safely and effectively treat corneal vascularization and inhibit fibrosis while alluding to b

89 tor (VEGF) signaling profoundly affects both vascularization and innervation of the pancreatic islet.

90 Tissue vascularization and integration with host circulation re

91 itis, calcinosis, acroosteolysis, and distal vascularization and is sensitive for calcinosis and acro

92 nd invasive MDA-MB-231 tumors display higher vascularization and less mature ECM, significantly enhan

93 g mechanisms mediate neural tube and retinal vascularization and maintain the BBB and BRB.

94 The transplanted BM/islets showed signs of vascularization and migration from the renal capsule int

95 It is generally accepted that vascularization and oxygenation of pancreatic islets are

96 reatments that have a direct effect on tumor vascularization and perfusion.

97 The distal vagina also showed increased vascularization and perivascular fibers containing NPY.

98 in endothelial cells to enable intracerebral vascularization and proper expression of molecular marke

99 nate-pretreated hMSC enhanced wound closure, vascularization and re-epithelialization and confirmed t

100 arge bone defects is limited by insufficient vascularization and slow bone regeneration.

101 othelial growth factor (VEGF) to enhance jaw vascularization and stabilize the major mandibular arter

102 in disease severity and delayed the onset of vascularization and stromal keratitis.

103 inding was associated with an impaired early vascularization and stromal tissue growth as well as red

104 hesized that burn injury would enhance early vascularization and subsequent bone formation of subcuta

105 ate a mechanism that controls aberrant tumor vascularization and suggest that targeting Endo-MT may o

106 Islet grafts were assessed for the degree of vascularization and total cellular insulin content.

107 he obesity-dependent tumour ASC recruitment, vascularization and tumour growth promotion.

108 fibrotic group had marked bleb scarring and vascularization and worse logMAR visual acuity.

109 ation of this adhesion inhibitor allowed for vascularization and wound healing, and maintained local

110 vo with regard to left ventricular function, vascularization, and amelioration of apoptosis and hyper

111 yperplasia, epicardial activation, increased vascularization, and causes cardiomegaly through persist

112 ds out for its multiple effects on immunity, vascularization, and cell migration.

113 monstrated superior structural organization, vascularization, and contractile function of fully diffe

114 malignant process, including proliferation, vascularization, and dissemination.

115 influenced by baseline PED height, degree of vascularization, and drug type.

116 types are responsible for matrix deposition, vascularization, and injury response.

117 smaller histological lesions, reduced tumor vascularization, and less lung metastases.

118 cantly reduced immunosuppression, intratumor vascularization, and local and metastatic breast cancer

119 tyrosine residues facilitates the survival, vascularization, and metastatic spread of breast tumors.

120 ted with increased insulin signaling, muscle vascularization, and percent cardiac output to muscle ra

121 ting differing host responses, mechanisms of vascularization, and proteolytic activity.

122 tokines critically involved in inflammatory, vascularization, and remodeling processes.

123 ment of hematopoietic stem cells, reparative vascularization, and reperfusion of the ischemic muscle.

124 characterized by intense pain, alteration of vascularization, and skin necrosis.

125 y compared, and optimal construct thickness, vascularization, and survival kinetics are unknown.

126 umerous factors mediating follicular growth, vascularization, and ultimately oocyte release via folli

127 odeling and have promise as therapeutics for vascularization applications.

128 Several pre-vascularization approaches have been developed to increa

129 The results suggest that mineralization and vascularization are coupled by localized secretion of pa

130 Current treatments of corneal vascularization are limited in efficacy and elicit undes

131 Three patterns of rhizophore vascularization are present in Selaginella and each is c

132 A molecular environment that promotes vascularization around human carcinomas can materialise

133 ency of DPC from balding scalps in fostering vascularization around the hair follicle may contribute

134 hed MSCs cause a dramatic increase in tissue vascularization as well as an induction of peripheral ne

135 VEGF receptor that mediates endothelial cell vascularization, as a mutant p53 transcriptional target

136 iposity, with a parallel increase in adipose vascularization associated with reduced circulating none

137 eIf2alpha) levels, as well as a reduction in vascularization-associated gene expression (Flt1, Vegf1,

138 A rapid and stable bone vascularization at an early stage of implantation is ess

139 Devices explanted showed vascularization at the end of 2, 6, and 12 months with o

140 hil-T cell interactions in the regulation of vascularization at the maternal-fetal interface.

141 e cell delivery system utilizing appropriate vascularization at the site of cell implantation that re

142 e employed to enhance endothelial-derived EV vascularization bioactivity.

143 have been shown to regulate wound and tumor vascularization by different mechanisms.

144 chambers in nude mice, cardiopatches undergo vascularization by host vessels and continue to fire Ca(

145 t mice showed significantly enhanced hepatic vascularization by micro-computed tomography and histolo

146 f endothelial Nrf2 enhanced EC sprouting and vascularization by suppression of Dll4/Notch signaling i

147 g can reveal additional means by which tumor vascularization can be inhibited by pharmacological inte

148 t, under conditions of stress, inappropriate vascularization can lead to disease.

149 through the induction of angiogenesis, tumor vascularization can occur through the nonangiogenic mech

150 f green fluorescent protein(+)/Tie2(+) EPCs, vascularization, cell proliferation, and apoptosis were

151 )/Tie2(+) EPCs, numbers of circulating EPCs, vascularization, cell proliferation, apoptosis, and immu

152 e, evaluated by tumor-to-blood [T/B] ratio), vascularization (cerebral blood volume [CBV]), and vascu

153 To determine if islet vascularization changes in response to insulin resistanc

154 llowing stroke while increasing peri-infarct vascularization compared to nonporous hydrogel controls

155 receptor and AKT and reduced decreased tumor vascularization compared with vehicle.

156 BUT), conjunctival congestion, corneal haze, vascularization, conjunctivalization, and limbal stem ce

157 We found that the cerebral vascularization deficit of nft (y72) mutants is caused b

158 t MIP-2 levels is responsible for suppressed vascularization detected in mice treated with anti-IL-7

159 ffeine did not interfere with normal retinal vascularization development but selectively protected ag

160 grade gliomas are characterized by exuberant vascularization, diffuse invasion, and significant chemo

161 r 1.5 million individuals suffer from cornea vascularization due to genetic and/or environmental fact

162 Poor vascularization during adipose tissue proliferation caus

163 revealed similar results, with a decrease in vascularization during therapy.

164 ed AnaLysis ; GE Healthcare, Milwaukee, Wis) vascularization flow index ( VFI vascularization flow in

165 interval ]: 0.90, 0.98) versus 0.899 for VFI vascularization flow index (95% CI confidence interval :

166 e interval : 0.82, 0.97) versus 0.67 for VFI vascularization flow index (95% CI confidence interval :

167 aukee, Wis) vascularization flow index ( VFI vascularization flow index ).

168 actional moving blood volume values than VFI vascularization flow index for intra- and interobserver

169 oving blood volume performed better than VFI vascularization flow index in repeatability studies.

170 FMBV fractional moving blood volume and VFI vascularization flow index produced significantly differ

171 Linear regression of VFI vascularization flow index versus FMBV fractional moving

172 Mean VFI vascularization flow index was 2.26 +/- 0.96 (range, 0.1

173 Owing to the importance of vascularization for the clinical applicability of tissue

174 al translation of this approach in long-term vascularization for tissue engineering and treatment of

175 reservoir of effectors that facilitate tumor vascularization, growth, and metastasis.

176 viability acutely following trauma in which vascularization has been compromised would be beneficial

177 These results indicate that VEGF-A and islet vascularization have a lesser role in adult islet functi

178 ulation of molecules involved in myogenesis, vascularization, hypertension, hypertrophy (associated w

179 or of cancer growth via modulation of tumour vascularization, immune response and metastasis formatio

180 d in significantly earlier normoglycemia and vascularization, improved glucose tolerance, and increas

181 a plug assay and decreased VEGF-A-stimulated vascularization in a mouse ear model.

182 Vascularization in CIA was determined by immunohistochem

183 table to Th17 cell differentiation and joint vascularization in CIA.

184 ions, color Doppler US failed to demonstrate vascularization in four (33.3%) lesions, which were posi

185 scular defects characterized by both reduced vascularization in intersegmental vessels, decreased pro

186 egulation of TGF-beta2 may increase aberrant vascularization in KS tumors through increased capillary

187 In this study, we assessed wound and tumor vascularization in mice with genetic ablation of both in

188 We document rhizophore vascularization in nine Selaginella species using cleare

189 permits the spatiotemporal analysis of organ vascularization in normal mice and in mouse strains with

190 s and source of endothelial cells to promote vascularization in regenerative strategies.

191 Vascularization in response to anti-vascular endothelial

192 Outcomes were vascularization in retinal zone III without a prior need

193 parisons with the architecture of rhizophore vascularization in Selaginella.

194 homing, differentiation of osteoclasts, and vascularization in the CIA effector phase.

195 flow, providing a new target for modulating vascularization in the clinic.

196 non-invasive assessment of pathologic ileal vascularization in the course of Crohn's disease.

197 tered immune cell responsiveness and reduced vascularization in the heart.

198 nd liver damage, promoted abnormal labyrinth vascularization in the placenta, and decreased fetal gro

199 del of vasculogenesis, we observed increased vascularization in the presence of breast cancer CAFs co

200 of PGC-1alpha during normal and pathological vascularization in the retina.

201 NFalpha enhanced immune activity and altered vascularization in the tumor bed.

202 ssion abrogated GSC transdifferentiation and vascularization in vitro, and inhibited VM in animal mod

203 cular endothelial growth factor A and, thus, vascularization, increased placental fetal capillary vol

204 Initial US echogenicity and vascularization influence the ablation outcome.

205 of scAAV8G9-optHLA-G1 + G5 prevented corneal vascularization, inhibited trauma-induced T-lymphocyte i

206 o macitentan treatment reduced tumor growth, vascularization, intravasation, and metastatic progressi

207 Aberrant vascularization is a hallmark of cancer progression and

208 s into islets occurs postnatally, when islet vascularization is already complete.

209 As vascularization is an important factor for the distribut

210 ifferentiation, but its relevance for glioma vascularization is unknown.

211 extended follow-up is needed because retinal vascularization is usually incomplete.

212 singly, even after 3 months of reduced islet vascularization, islet architecture and beta-cell gene e

213 nt dramatically reduced pancreatic and islet vascularization, leading to reduced beta-cell proliferat

214 Stromal thinning, vascularization, lipid deposition, and against-the-rule

215 These compensatory changes in islet vascularization may influence whether beta-cells can ade

216 ng in a rabbit model, resulting in increased vascularization, more mature collagen fiber organization

217 In vivo implantation suggests vascularization of 3D bioprinted cardiac patches with en

218 blishment of simple methods for the in vitro vascularization of 3D constructs and better maturation o

219 Therefore, primary vascularization of allografts governs their immunogenici

220 together, these results suggest that primary vascularization of allografts is associated with a lack

221 (EPCs) into microvessels contributes to the vascularization of endometriotic lesions.

222 developing blood vessels contributes to the vascularization of endometriotic lesions.

223 The requirement for immediate vascularization of engineered dental pulp poses a major

224 the inflammatory status and the preexisting vascularization of high-risk patients undergoing corneal

225 lar peritubular cells, via PEDF, may prevent vascularization of human seminiferous tubules.

226 marrow stem/progenitor cells that accelerate vascularization of ischemic areas.

227 how that CNS-resident radial glia direct the vascularization of neighboring tissues during developmen

228 port that Nck is required for the growth and vascularization of primary tumors and lung metastases in

229 HO-1 inhibition by SnPP reduced growth and vascularization of RMS tumors in vivo accompanied by ind

230 roles in controlling angiogenesis, including vascularization of solid tumors.

231 Abnormal vascularization of solid tumours results in the developm

232 injury, and showed significantly attenuated vascularization of sponge implants.

233 Growth and vascularization of subcutaneous tumor allografts was enh

234 ults showed a significantly higher degree of vascularization of the callus than of the healthy perios

235 ular resistance index (RI) and the degree of vascularization of the callus with a subjective radiolog

236 g in endothelial cells (ECs) is required for vascularization of the central nervous system (CNS) and

237 e of this intercellular communication is the vascularization of the central nervous system (CNS), whi

238 MMP-2) plays important roles in invasion and vascularization of the central nervous system and repres

239 nonical WNT signaling is required for proper vascularization of the CNS during embryonic development.

240 ogenous Sema3A protein inhibits Vegf-induced vascularization of the cornea.

241 anisms that prevent angioblast migration and vascularization of the developing cornea are not clear.

242 ifferentiation process that orchestrates the vascularization of the developing YS with the induction

243 tant mice results in ectopic angioblasts and vascularization of the embryonic mouse corneas.

244 pertrophic chondrocyte apoptosis and impairs vascularization of the growth plate.

245 mpletely blocking the vascular drive for the vascularization of the immature retina.

246 cells would reduce their ability to improve vascularization of the infarct area seen after transplan

247 ks after MI revealed significantly increased vascularization of the infarct areas and reduced myocard

248 In addition to vascularization of the lens through a capsular dehiscenc

249 on, inflammation, fibrous encapsulation, and vascularization of the material.

250 In addition, burn injury enhanced vascularization of the ossicles (P < 0.05).

251 rogeneous disorder characterized by abnormal vascularization of the peripheral retina, which can resu

252 Vascularization of the regenerating tissue is selectivel

253 examine the development and consequences of vascularization of the tuberculous granuloma in the zebr

254 The inefficient vascularization of tumor tissue also limits the penetrat

255 estigated the influence of allograft primary vascularization on alloimmunity, rejection, and toleranc

256 l growth factor isoform A (VEGF-A) and islet vascularization on beta-cell function and survival using

257 ry (P = 0.03), persistent or increased tumor vascularization on the interim PET (DeltaBF cutoff = -30

258 icant effect of ferrogel actuation on muscle vascularization or perfusion was found.

259 n of endothelial cells (ECs) for therapeutic vascularization or tissue engineering is a promising met

260 ntrolled the release of VEGF, which promotes vascularization, or dexamethasone, an anti-inflammatory

261 NS-resident progenitors in the regulation of vascularization outside the CNS, serving as a paradigm f

262 c volume, urethral volume, and genitourinary vascularization over time in response to estradiol-induc

263 Deep corneal vascularization (P = .012), preexisting active inflammat

264 g suture removal (P = .01), and suture-tract vascularization (P = .04) significantly influenced posto

265 islets displayed obesity-induced growth and vascularization patterns that were reversed by leptin tr

266 xic compared with normoxic exosomes of tumor vascularization, pericyte vessel coverage, GBM cell prol

267 n may activate endothelial EVs towards a pro-vascularization phenotype, which could have implications

268 nd that freshly isolated cells have a higher vascularization potential.

269 en-deficient mice severely impaired fracture vascularization, precluded bone union, and resulted in r

270 After retreatment with IVB, retinal vascularization proceeded minimally and slowly.

271 y associated with capillaries, but the islet vascularization process during embryonic organogenesis s

272 this evidence, we found that increased tumor vascularization (reflected by changes in tumor vascular

273 e ability of endothelial EVs to induce a pro-vascularization response.

274 ng Tauber staging), central corneal disease (vascularization, scarring, ulceration, and conjunctivali

275 However, nidus vascularization still persisted after treatment in four

276 on clinical examination were haze, scarring, vascularization, stromal edema, pigment clumps on endoth

277 ic details, indications, graft size, corneal vascularization, surgical complication, rejection episod

278 transplantation significantly enhances graft vascularization, survival, and proliferation of grafted

279 transplantation significantly enhances graft vascularization, survival, proliferation, and the densit

280 Therefore, germinal zone vascularization sustains NPC proliferation in the prenat

281 vels were associated with a higher degree of vascularization than the regions without drug signals (p

282 se questions, we found that with progressive vascularization, the expression level in EECs of the nut

283 Vascularization underlies the success of guided bone reg

284 ile tissue ingrowth was tracked by measuring vascularization using magnetic resonance imaging in the

285 ility to selectively target tumor growth and vascularization using tubulin-destabilizing agents.

286 patches were transplanted in rats, and their vascularization was assessed.

287 Also, the anterior extent of retinal vascularization was decreased (mean, 1.76 disc diameters

288 s [DD] vs. 4.48 DD), and the rate of retinal vascularization was delayed (mean, 0.11 DD/week vs. 0.23

289 Distal vascularization was detected in 26 patients (59%) and 30

290 compared with WT; however, adaptive cardiac vascularization was increased in some mutant mice and re

291 ce-like corneal opacities, prominent corneal vascularization was present in 2 patients mimicking inte

292 , calcifications, acroosteolysis, and distal vascularization was recorded.

293 A was inactivated in adult beta-cells, islet vascularization was reduced twofold.

294 osteoid osteoma (edema, hyperemia, and nidus vascularization) were considered at baseline and at imag

295 nduced doppel overexpression in ECs enhanced vascularization, whereas doppel constitutively colocaliz

296 NA methylation are a feature of sorghum root vascularization, which we confirmed using tissue-specifi

297 showed similar tendencies toward decreasing vascularization, with a stronger decrease in tumors trea

298 monstrated reduced invasion, metastasis, and vascularization, with opposing effects produced by ROBO1

299 Gal-1 in prostate cancer cells reduced tumor vascularization without altering expression of other ang

300 is characterized by enhanced cell division, vascularization, wound healing and adjustment of host ad