ライフサイエンスコーパス: vasculature

1 reous (more recently termed persistent fetal vasculature).

2 for DHA retention and metabolism in the gut vasculature.

3 ischemia and their position relative to the vasculature.

4 as approximately 10-fold smaller than glioma vasculature.

5 adjacent tissues or involvement of critical vasculature.

6 transdifferentiation occurs adjacent to the vasculature.

7 er cells, but were ineffective against tumor vasculature.

8 te layer-by-layer analysis of injured ocular vasculature.

9 dothelial sprouting in the postnatal retinal vasculature.

10 m those of RAS stimulation in the kidney and vasculature.

11 d by the abnormal development of the retinal vasculature.

12 ling plays in the development of the retinal vasculature.

13 health and function of the intimal layer in vasculature.

14 growth, VEGF expression and decreased tumour vasculature.

15 ke cancer cells, immune cells, and the tumor vasculature.

16 obal decrements to structural aspects of the vasculature.

17 fied a novel role for Panx1 in the lymphatic vasculature.

18 plant tissues, including the shoot, root and vasculature.

19 suppressed and maintains a quiescent, patent vasculature.

20 airways, the parenchyma, and the surrounding vasculature.

21 plicated in Wnt7a/Wnt7b signaling in the CNS vasculature.

22 pecific delivery that is restricted to brain vasculature.

23 y, mimicking the changes that exist in tumor vasculature.

24 tact both neuronal synapses and the cerebral vasculature.

25 aracterized by loss and obliteration of lung vasculature.

26 till present challenges in evaluating ocular vasculature.

27 ow and pressure distribution in the cortical vasculature.

28 and increased cell adhesion molecules in the vasculature.

29 ng a regulatory function for this SNP in the vasculature.

30 by inadequate perfusion and hyper-permeable vasculature.

31 -varying spatial distributions of angiogenic vasculature.

32 how to direct them to stably integrate into vasculature.

33 ecies show enriched expression in developing vasculature.

34 ature and the neurons and glia that abut the vasculature.

35 ancer immunotherapy via effects on the tumor vasculature.

36 ulature, and valves, as well as the systemic vasculature.

37 eased deposition of collagen in the occluded vasculature.

38 f inoculation but reduced spread through the vasculature.

39 ical for initial migration of PMN out of the vasculature.

40 of the complexities of BMP signalling in the vasculature.

41 ling through selective expansion of perfused vasculature.

42 how marked underdevelopment of the placental vasculature.

43 ategy for adaptive homoeostasis in the adult vasculature.

44 dogenous multimodal contrast provided by the vasculature.

45 s with gray and white matteras well as dense vasculature.

46 terface between primary tumor and mesenteric vasculature.

47 ribute to its proinflammatory effects in the vasculature.

48 the influence of functional tumor-associated vasculature.

49 pic alteration and maturation of the tumor's vasculature.

50 emical agent and a pressure wave through the vasculature.

51 e that recapitulates barrier function of the vasculature.

52 ative breast cancer and the associated tumor vasculature.

53 ne function, may also converge to act on the vasculature.

54 rated tortuous and disorganized intratumoral vasculature.

55 traight migration, guided by lung-associated vasculature.

56 tivity were up-regulated in the hypertensive vasculature.

57 ly along with the soft tissue comprising the vasculature.

58 evascularized and integrated with the host's vasculature, a feature not seen in other s.c.

59 mulates with Fe in the cells surrounding the vasculature, a pattern previously shown to be determined

60 Within the liver vasculature, adenosine triphosphate is converted into py

61 in male mice, reflecting potential shifts in vasculature, amino acid transport, serotonin homeostasis

62 ich was associated with restoration of renal vasculature and amelioration of hypoxia through increase

63 cord and their potential impact on the local vasculature and blood-spinal cord barrier (BSCB).

64 age- and gonadotropin-dependent increases in vasculature and branching surrounding follicles.

65 A (VEGFA) promoter showed defective ovarian vasculature and decreased ovulatory responses.

66 stead, many of these neutrophils reenter the vasculature and have a preprogrammed journey that entail

67 lacked apparent deformities in the embryonic vasculature and heart, the placental labyrinths of these

68 elucidate an unexpected role of TH1 cells in vasculature and immune reprogramming.

69 roles in development and maintenance of the vasculature and in angiogenesis.

70 er allowed visualization of tumor-associated vasculature and its contrast against normal blood vessel

71 ized preferentially to the vicinity of tumor vasculature and macrophages in the tumor.

72 drug delivery systems in targeting the micro-vasculature and micro-environments of breast cancer tumo

73 renin-angiotensin system regenerated kidney vasculature and normalized Tgf-beta and endothelin-1 gen

74 50 nm provided better visualization of tumor vasculature and penetration through thicker tumors than

75 elegans with conserved effects in the murine vasculature and potential implications for mammalian vas

76 op pharmacological therapies that target the vasculature and regulate diverse aspects of hematopoiesi

77 hat the local release of drug into the tumor vasculature and resulting high drug concentration can al

78 Dysregulated crosstalk between the vasculature and retinal neurons is increasingly recogniz

79 is predominantly expressed in both the root vasculature and root tips, in a distinct developmental p

80 restored the delayed development of retinal vasculature and the intralaminar capillary networks, sup

81 vated and enter target organs, including the vasculature and the kidney, in this disease.

82 ar communication occurs between cells of the vasculature and the neurons and glia that abut the vascu

83 of phosphorescence signals from the retinal vasculature and tissue.

84 in the postnatal development of the retinal vasculature and under conditions of ischemia-reperfusion

85 ympathetic outflow directed to the cutaneous vasculature and, correspondingly, greater reductions in

86 ntify molecular targets of DHI in resistance vasculatures and demonstrate its role in vascular functi

87 from prohypertensive actions in the kidney, vasculature, and brain, to effects in the skin that atte

88 dings reveal a novel function of the retinal vasculature, and imply that in normal neonatal mice, oxy

89 y means of directly altering the myocardium, vasculature, and metabolism.

90 es, qualitative evaluation of iris and tumor vasculature, and quantitative vessel density.

91 lex (guard cells and subsidiary cells), root vasculature, and root cortex.

92 um, myocardium, coronary arteries, pulmonary vasculature, and valves, as well as the systemic vascula

93 cardiovascular organs, such as the heart and vasculature, and with the brain.

94 ture and stiffness of the proximal pulmonary vasculature are independent predictors of outcome in PAH

95 nning nearly all size scales of native human vasculature are readily generated with unprecedented use

96 exchange of matter between cell network and vasculature are ubiquitous in numerous brain pathologies

97 Blood and lymphatic vasculatures are intimately involved in tissue oxygenati

98 onents of the engineered tissue, such as the vasculature, are of murine origin.

99 uce the formation of a lymphatic and a blood vasculature around themselves.

100 es lethal aGVHD and identifies the lymphatic vasculature as a novel therapeutic target in the setting

101 e of CCN3-deficient mice is intrinsic to the vasculature, as AAA was not exacerbated in WT animals th

102 auterine life is relaxation of the pulmonary vasculature at birth, allowing for a rapid increase in p

103 these vesicles can selectively bind inflamed vasculature because they possess intact targeting molecu

104 umor and healthy cells, biomarker entry into vasculature, biomarker elimination from plasma, and subj

105 chest with mild compression of the pulmonary vasculature but no other evidence of lymphoma.

106 of pNPs increased, its Pd decreased in tumor vasculature, but remained largely unchanged in healthy v

107 loaks" the luminal surfaces within the renal vasculature by covering the point of contact between don

108 was examined both in conduit and resistance vasculature by ex vivo aortic rings.

109 es and clinical imaging properties, analyzed vasculature by immunohistochemistry and electron microsc

110 Tumors induce their heterogeneous vasculature by secreting vascular endothelial growth fac

111 We focused on phenotypes of hypocotyl vasculatures caused by double mutation in ERECTA (ER) an

112 , luteal formation/regression and associated vasculature changes lead to tissue remodeling during eac

113 These vasculature changes were accompanied with features of BS

114 aluate the roles of CAFs in modulating tumor vasculature, chemoresistance, and disease progression.

115 ubmandibular salivary gland development, the vasculature co-develops with the epithelium during branc

116 In the lymphatic vasculature, collecting vessels generate rapid contracti

117 ultrasound in evaluation of renal transplant vasculature compared to 2-dimensional (2D) Duplex ultras

118 the formation of a space-filling and mature vasculature compared with hydrogel materials that promot

119 Derangements in the host vasculature contribute to the cardinal manifestations of

120 eframing current evidence in this model, the vasculature could become an important therapeutic target

121 e, but remained largely unchanged in healthy vasculature, demonstrating a trend similar to tumor sele

122 The role of fluid shear stress in vasculature development and remodeling is well appreciat

123 ur knowledge about the genetic regulation of vasculature development, from the scale of single genes

124 aracterized by silencing of genes related to vasculature development.

125 still remains limited for cancer, heart, or vasculature diseases.

126 e with blood vessels and help to pattern the vasculature during development.

127 ation of epithelial pattern formation by the vasculature during organ development and regeneration is

128 results suggest that the evolution of tumor vasculature during progression may influence drug delive

129 sed excessive radial growth of the hypocotyl vasculature during secondary growth.

130 ntimicrobial proteins) are released into the vasculature during sepsis where they contribute to host

131 w noninvasive detailed evaluation of retinal vasculature during surgical procedures and in patients w

132 hts into drug vector distribution changes in vasculature during tumor progression, we combined intra-

133 n plants is crucial because the evolution of vasculature enabled plants to thrive on land.

134 D276 ADCs killed both cancer cells and tumor vasculature, eradicating large established tumors and me

135 GF therapy is concerned with delayed retinal vasculature, eye, and brain development of preterm infan

136 n of leukocytes and humoral factors from the vasculature, first across the endothelial blood-brain ba

137 hesion of infected erythrocytes to the brain vasculature, followed by rupture and release of contents

138 ocarriers rely principally on abnormal leaky vasculature for tumor access, a transcytosis transport p

139 ce of ABA biosynthesis in guard cells versus vasculature for whole-plant stomatal regulation is uncle

140 the formation of less organized host-derived vasculature formation.

141 Lymphatic vasculature generated by this approach exhibits the majo

142 The retinal vasculature grows towards the periphery ahead of differe

143 s that a combinatorial regimen targeting the vasculature, GSCs, and GECs, using drugs already approve

144 enesis; however, it is not known whether the vasculature has instructive effects on the epithelium.

145 theranostic nanosystem consisting of a tumor vasculature-homing peptide (CGKRK) fused to a pro-apopto

146 l cells (ASCs) for engineering the pulmonary vasculature in a decellularized rat lung scaffold.

147 nsin II (AngII) affects transcriptome in the vasculature in a region-specific manner, which may help

148 udy, we provide a detailed picture of the BM vasculature in acute myeloid leukemia using intravital t

149 gression leads to differential remodeling of vasculature in central and endosteal bone marrow regions

150 missive to maturation and maintenance of the vasculature in CMT2D mice.

151 ulated sympathetic control of the peripheral vasculature in hypertension, no studies have examined in

152 ulated sympathetic control of the peripheral vasculature in hypertension, no studies have examined in

153 ions may contribute to enhanced leakiness of vasculature in Kindlin-2(+/-) mice.

154 aging approach to characterize the lymphatic vasculature in mesenteric tissue from controls or patien

155 VEGF-A (Ad-VEGF-A(164)) replicates the tumor vasculature in mice without tumor cells.

156 n developed to study changes in the cerebral vasculature in numerous neuropathological processes incl

157 ovarian architecture and essential roles of vasculature in organizing follicles to allow future stud

158 formation about alterations of the pulmonary vasculature in pulmonary arterial hypertension (PAH) is

159 as well as metabolic regulations of cerebral vasculature in response to changes in pressure or cerebr

160 exhibit markedly decreased left ventricular vasculature in response to transverse aortic constrictio

161 way specifies distinct cell types around the vasculature in subepidermal layers of both root and shoo

162 these results provided automated imaging of vasculature in the earliest stages of carcinogenesis fro

163 white belly spot, all have persistent fetal vasculature in the eye, and 50% have webbed digits.

164 rticles enable fast in vivo imaging of blood vasculature in the mouse brain and hindlimb in the NIR-I

165 ration, causing a partial obstruction of the vasculature in the regenerated lung.

166 In line with these data, the vasculature in vimentin knockout (VimKO) embryos and pla

167 ology allowed us to study the normal retinal vasculature in vivo with better depth resolution than pr

168 mug/mL cAMP had Pd that approximated healthy vasculature in vivo.

169 ation of new blood vessels from pre-existing vasculature, in order to obtain nutrients required for c

170 death, female fertility, platelet function, vasculature inflammation, and diet-induced atheroscleros

171 The vasculature influences the progression and resolution of

172 oglial volume changes, and ion exchange with vasculature into a comprehensive model to elucidate the

173 quent monocyte infiltration from the retinal vasculature into the inner retina that replenishes the l

174 In turn, leakage from the vasculature into the parenchyma causes brain swelling an

175 sis, wherein endothelial cells from existing vasculature invade the surrounding matrix to form new va

176 into the tumor tissue caused by its abnormal vasculature is a major obstacle to the treatment of canc

177 A defining feature of this vasculature is a physical blood-brain barrier (BBB).

178 ing how the global architecture of the renal vasculature is achieved.

179 Because the vasculature is affected in chronic renal transplant dysf

180 ive immune cell accumulation in the cerebral vasculature is associated with compromised integrity of

181 s advanced our knowledge on how the coronary vasculature is built and revealed unexpected features of

182 Brain vasculature is conventionally represented as straight cy

183 volved to protect the integrity of the human vasculature is critical to our ability to predict and co

184 nd to stimulate angiogenesis at a site where vasculature is deficient and healing is compromised.

185 The retinal vasculature is easily imaged, and may be a surrogate bio

186 Solid tumor vasculature is highly permeable, allowing the possibilit

187 Visualizing ocular vasculature is important in clinical ophthalmology becau

188 The renal vasculature is integral to the physiologic function of t

189 We found that pericyte coverage of tumor vasculature is inversely correlated with GBM patient sur

190 The cutaneous vasculature is involved in many diseases.

191 In reality, the vasculature is more complicated with branching and coili

192 The lymphatic vasculature is not considered a formal part of the immun

193 hether a similar cross-talk regulates the BM vasculature is not known.

194 thetically-mediated control of the cutaneous vasculature is not only preserved, but also exaggerated

195 The atherosclerotic coronary vasculature is not only the culprit but also a victim of

196 3D imaging of the bone vasculature is of key importance in the understanding of

197 The renal vasculature is required for blood filtration, blood pres

198 Similarly, oxidative balance in the vasculature is tightly regulated by a wealth of pro- and

199 mpromises smooth muscle cell coverage of the vasculature leading to embryonic lethality.

200 We further demonstrated that dilated vasculature, loss of vascular integrity resulting in ext

201 nal glomerular functions rely on specialized vasculature maintained by VEGF that is produced by neigh

202 unction of smooth muscle cells (SMCs) in the vasculature may cause defects associated with HGPS.

203 The known physiologic effects of EDN1 on the vasculature may explain the pattern of risk for the five

204 that preventing degradation of the endosteal vasculature may improve current paradigms for treating A

205 signaling via locally generated SPMs in the vasculature may represent a novel homeostatic mechanism

206 tis and systemic comorbidities affecting the vasculature, metabolism, and bone.

207 3D collagen matrix that emulates anatomical vasculature more closely than inorganic polymers, thus t

208 AMD, increased need for visualization of the vasculature must be taken into account.

209 e with the expression of OsK5.2 in the plant vasculature, mutant plants displayed a reduced K(+) tran

210 e sodium-hydrogen exchanger in the heart and vasculature (NHE1 isoform) and the kidneys (NHE3 isoform

211 is study was to compare the distal pulmonary vasculature of <2 mm in diameter in Systemic Sclerosis (

212 lls, as well as TGFbeta1 upregulation in the vasculature of 9p21 risk allele carriers.

213 urbit[6]uril (CB6) contrast agent within the vasculature of a living rat.

214 t MTI1 and DEP1 were mainly expressed in the vasculature of all plant parts.

215 , TRU1 is highly expressed in the leaf trace vasculature of axillary internodes, while in teosinte, t

216 MtLAX2 is expressed in nodule primordia, the vasculature of developing nodules, and at the apex of ma

217 In contrast, the vasculature of DSA-exposed allogeneic islet grafts was d

218 , provides new opportunities for imaging the vasculature of entire organs with a spatial resolution b

219 rcumventricular organs in the brain or leaky vasculature of late-stage intracranial tumors.

220 lls, and in the meristem, invasion zone, and vasculature of nodules.

221 The central vasculature of plant roots is protected by a hydrophobic

222 een Fli1 and FOXO3A was also observed in the vasculature of scleroderma patients.

223 trated that ALMT9 is highly expressed in the vasculature of shoots and roots.

224 The vasculature of the central nervous system (CNS) forms a

225 suggest that a strong auxin response in the vasculature of the treated leaf and auxin signaling in t

226 The unique characteristics of the tumor vasculature offer the possibility to selectively target

227 -8 mum in diameter can circulate through the vasculature, offering possibilities for ultrasound (mole

228 blood cells when injected directly into the vasculature or diluted into blood from wild type mice.

229 helial cells, and blood cells in the retinal vasculature, other important cell classes, such as retin

230 cognized, how these progenitors regulate the vasculature outside the CNS remains largely unknown.

231 r spheroids, and to track the degradation of vasculature over time within extracted murine pancreatic

232 In the vasculature, p66Shc-induced ROS engenders endothelial dy

233 ld improve our understanding of the role the vasculature plays in bone disease.

234 ythroblasts initially navigate the embryonic vasculature prior to establishing a deformable cytoskele

235 y intravenous injection, to target the tumor vasculature, produce immune activation and tumor cell ki

236 Vasculature proliferation also involves the cell cycle r

237 an essential role in the development of the vasculature, promoting vascular quiescence and long-term

238 agents) are detected and tracked within the vasculature, provides new opportunities for imaging the

239 t capacity of adipose tissue surrounding the vasculature (PVAT) and has been implicated in resultant

240 Construction of follicle-vasculature relationship maps indicated age- and gonadot

241 ting cancer cell invasion into the lymphatic vasculature remain little understood.

242 nderlying the morphogenesis of the lymphatic vasculature remain to be fully understood.

243 enesis of MS; however, its role in the brain vasculature remains unknown.

244 nt monocytes are retained in the bone marrow vasculature, representing an important reservoir of marg

245 Human endothelial cells seeded via native vasculature restore perfusability.

246 ed IFNgamma-induced regression of the tumour vasculature, resulting in arrest of blood flow and subse

247 estigation of aggrecan presence in the human vasculature revealed that aggrecan and aggrecan cleavage

248 . administration of these NPs can target WAT vasculature, stimulate the angiogenesis that is required

249 icial vasculature, they migrated towards the vasculature structure.

250 Targeting stiffness-induced changes in the vasculature, such as CCN1, is therefore a potential yet

251 iscuss how other properties of the lymphatic vasculature, such as mechanisms of lymphatic contraction

252 ary and form an interface with the pituitary vasculature, suggesting that preoptic AgRP2 neurons are

253 lyses of the foveal avascular zone (FAZ) and vasculature surrounding the FAZ were performed on the au

254 brain is supplied with blood by specialized vasculature that is structurally and functionally distin

255 the disease, induce an aberrant fenestrated vasculature that permits the accumulation of high levels

256 key structural and functional changes in the vasculature that promote hypoperfusion and ischemia, whi

257 e pancreatic tumor extracellular matrix, the vasculature, the immune system, and metabolism, and disc

258 Due to its vasculature, the temporal pole is not commonly completel

259 led chemical stimulation from the artificial vasculature, they migrated towards the vasculature struc

260 essential to maintain the pancreatic cancer vasculature through a VEGF-independent mechanism.

261 in patterning and stabilization of the early vasculature through production and maintenance of the va

262 igh endogenous auxin signaling occurred near vasculature tissue and the outer layer and glume primord

263 stand how plants connect and reconnect their vasculature to a wide variety of organisms.

264 framework for quantitative imaging of tumor vasculature to derive a spatially informed, prognostic g

265 protein-coding mRNAs can move via the phloem vasculature to distant tissues, where they may act as no

266 ical step in cancer cell transit through the vasculature to metastasize.

267 treatment option that targets GBM-associated vasculature to mitigate the growth of GBMs.

268 n which PF4 interacts with components of the vasculature to modulate cellular events.

269 he engineered plants allocate more N via the vasculature to the shoot and seeds and produce more biom

270 from whence it is distributed via embryonic vasculature toward cotyledon tissues.

271 depends on their ability to extravasate from vasculature towards the target tissue.

272 1616 1616 References 1616 The plant vasculature transports water, sugars, hormones, RNAs and

273 ed microenvironment caused by abnormal tumor vasculature triggering metabolic switches.

274 to maintain the physiological state of blood vasculature under inflammatory conditions.

275 can ligands mediate leukocyte rolling in the vasculature under shear forces.

276 A images of the superficial and deep retinal vasculatures using vessel-based and FAZ-based metrics.

277 e showed that adiponectin accumulates in the vasculature via T-cadherin, and the adiponectin-T-cadher

278 ctors, vasculogenic mimicry (VM), the mature vasculature (von Willebrand Factor) and tumor induced an

279 few decades, enhanced permeability of tumor vasculature was actively exploited for targeted delivery

280 ction chemotherapy failing to restore normal vasculature was associated with a poor prognosis.

281 The systemic vasculature was investigated using brachial artery flow-

282 hieves excellent delineation of the cerebral vasculature, was qualitatively and quantitatively superi

283 SS OCT en face images of choroidal vasculature were also captured and converted to binary i

284 En face SS-OCT images of the choroidal vasculature were binarized.

285 Plants have developed mechanisms to repair vasculature when such protections fail and to even initi

286 d recruited to the peritoneum membrane lumen vasculature where they reside through CX3C-chemokine rec

287 xpressed in endothelial cells throughout the vasculature, where it regulates L-arginine uptake.

288 P. aeruginosa adhered avidly to lung vasculature, where patrolling neutrophils and other immu

289 ed role in the formation of tumor-associated vasculature which could possibly offer potential novel t

290 amine selectively targets pre-existing tumor vasculature, which causes vascular shutdown and leads to

291 HUVECs yielded a Pd that approximated tumor vasculature while HUVECs treated with 25 mug/mL cAMP had

292 drug concentrations within a tumor and tumor vasculature while maintaining low systemic toxicity.

293 echniques, however, cannot resolve the human vasculature with all plexus in a non-invasive manner.

294 Targeting the tumor vasculature with antibody-drug conjugates (ADCs) is a pr

295 2+) or cAMP elevation, thereby supplying the vasculature with factors controlling hemostasis.

296 mise as a technique to visualize the retinal vasculature with lower risk and cost than fluorescein an

297 To evaluate tumor vasculature with optical coherence tomography angiograph

298 he highly permeable, but heterogeneous tumor vasculature, with the permeabilizing effects of mild (40

299 sualisation of calcified bone tissue and the vasculature within the calcified bone matrix.

300 oacoustic microscopy (PAM) images the ocular vasculature without using exogenous contrast agents, avo