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4 n atom replacing a sulfur atom), blocked the vasodilatory action of H2O2 on resistance vessels and re
7 th rats fed a LFD, HFD feeding abolished the vasodilatory actions of globular adiponectin (gAd) and i
8 microvascular endothelial cells (HMVEC) and vasodilatory actions on bovine coronary arteries and rec
10 pressure and adverse events consistent with vasodilatory activity of AKB-9778 emerged at doses of 22
11 ) and thereby provide a basis for the graded vasodilatory activity that is inversely proportional to
15 NO, (localization, diffusiveness, half-life, vasodilatory affects) have supported its potential role
16 arations, and to investigate the efficacy of vasodilatory agents on the level of intrinsic tone in th
22 generating angiotensin-(1-7), which induces vasodilatory and antiproliferative actions in the cardio
23 I(2) (prostacyclin) is a lipid mediator with vasodilatory and antithrombotic effects used in the trea
24 time course and degree to which mechanical, vasodilatory and cardiac mechanisms contribute to the in
26 rteries, and greater vasoreactivity (greater vasodilatory and constrictor responses) than age-matched
27 = 0.02) and dramatically reduced the overall vasodilatory and hyperaemic response (area under the cur
28 ter VEGFR2 activation, the mast cell-derived vasodilatory and inflammatory mediators may contribute m
30 roperties of angiotensin II (Ang II) and the vasodilatory and natriuretic properties of bradykinin an
31 kt and eNOS contributes to some of the acute vasodilatory and neuroprotective effects of thyroid horm
32 rease the availability of peptides that have vasodilatory and other vascular effects; they also inhib
36 cytochrome P450 (CYP) epoxygenases, possess vasodilatory, antiinflammatory, and fibrinolytic propert
40 ROLS: 3.73 +/- 0.71 mm, p<0.05), had greater vasodilatory (BAFMD%: Athletes: 8.21 +/- 1.78 vs. CONTRO
41 Of note was an apparent 10-fold increase in vasodilatory bradykinin that reversed after drug infusio
42 pacity on low-density lipoproteins), and HDL vasodilatory capacity (HDL ability to induce the release
43 paraoxonase-1 arylesterase activity, and HDL vasodilatory capacity (relative to control, P=0.039, P=0
46 vascular dysfunction resulting in diminished vasodilatory capacity and tissue hypoperfusion is associ
47 ly treadmill exercise would improve the poor vasodilatory capacity of collateral arteries isolated fr
48 rcise training improves endothelium-mediated vasodilatory capacity of hindlimb collateral arteries, a
50 he resistive reserve ratio, a measure of the vasodilatory capacity of the microcirculation and calcul
53 d flows and flow reserve suggest an impaired vasodilatory capacity, possibly due to residual damage o
55 r an upstream resistance site is under tonic vasodilatory control or a downstream site is under vasoc
56 ion neurons of birds use VIP and NO to exert vasodilatory control over blood flow to and within the a
60 fferences in skeletal muscle metabolism, not vasodilatory dynamics, must account for the augmented gl
63 Albumin-mediated S-nitrosylation and its vasodilatory effect directly depend on the concentration
64 on, an NO-trapping agent, reversed the basal vasodilatory effect of ACEI in the pulmonary vasculature
66 dothelial nitric oxide synthase and that the vasodilatory effect of endothelial nitric oxide synthase
69 ive K+ channels appear to play a role in the vasodilatory effect of testosterone in resistance arteri
70 with acetylcholine results in a significant vasodilatory effect on both conductance and resistance r
71 enous nitric oxide donor, caused a selective vasodilatory effect on renal conductance but not on resi
72 art disease is limited because of the potent vasodilatory effect that causes hypotension, and other s
76 ising cAMP content, have acute inotropic and vasodilatory effects in treating congestive heart failur
78 We investigated the hemodynamic and coronary vasodilatory effects of CGS-21680, a potent selective ad
79 ene name EDNRB)], the receptor mediating the vasodilatory effects of endothelin-1 (ET-1) is induced b
80 ence of aging and the menopause on the acute vasodilatory effects of estrogen using ex vivo human and
82 ing lung pathology consistent with competing vasodilatory effects on the normal and abnormal areas th
83 s often limited by the appearance of adverse vasodilatory effects such as headache or peripheral edem
84 DPPH, FRAP and ABTS assays and the in vitro vasodilatory effects were assessed using norepinephrine
86 , in addition to its direct bradycardiac and vasodilatory effects, can increase sympathetic discharge
87 serum sodium levels, and had more pronounced vasodilatory effects, compared with LeTx, as reflected b
88 and symptomatic improvement through balanced vasodilatory effects, neurohormonal suppression and enha
92 ,8,11-trienoic acid (14,15-EET) is a labile, vasodilatory eicosanoid generated from arachidonic acid
93 dothelial 15-lipoxygenase (15-LO) to several vasodilatory eicosanoids such as 11,12,15-trihydroxyeico
95 eurons as their main cellular source and the vasodilatory EP2 and EP4 receptors as their main targets
96 yramidal cells as their principal source and vasodilatory EP2 and EP4 receptors as their targets.
97 E) and neutral endopeptidase, which degrades vasodilatory factors (eg, ADM) and natriuretic peptides.
100 Arterial blood pressure is controlled by vasodilatory factors such as nitric oxide (NO) that are
101 ginine supplementation to completely restore vasodilatory function may be attributable to the down-re
103 ce, respectively) with regard to endothelial vasodilatory function, endothelial progenitor cell (EPC)
107 gic processes in which cardiac inotropic and vasodilatory functions are linked to specific aspects of
108 erein to modulate the vascular signaling and vasodilatory functions of nitric oxide (NO) during acute
109 tent oxidant) to generate carbon monoxide (a vasodilatory gas that has anti-inflammatory properties),
110 enzyme that degrades heme to generate CO (a vasodilatory gas), iron, and the potent antioxidant bili
111 chamber (8 degrees C to 10 degrees C) and a vasodilatory heat chamber (40 degrees C to 42 degrees C)
112 wice that of control fetuses at rest, during vasodilatory hyperaemia, and during hyperaemia plus incr
117 alatine ganglia, the source of nitroxidergic vasodilatory innervation of cerebral blood vessels.
121 O(2) demand is thought to be satisfied by a vasodilatory mechanism that results in increased blood a
124 sympathetic contractile agents and unaltered vasodilatory mechanisms may provide a means for maintena
125 agonist of the thromboxane receptor, whereas vasodilatory mechanisms of CO relied on the activation o
130 nduced mast cell-derived proinflammatory and vasodilatory mediator production in a VDR-dependent mann
131 does not restore HPV, indicating that other vasodilatory mediators besides NO also influence HPV in
133 ing perfusion to the small intestine via the vasodilatory molecule endothelial nitric oxide synthase
136 eoxy)-state subserves the release from Hb of vasodilatory nitric oxide (NO) bioactivity, it has not y
137 egatory, antiadhesive, antiinflammatory, and vasodilatory omega-3 (n-3) fatty acids (DHA and EPA) are
138 This effect is independent of any other vasodilatory or endothelial effects and is apparently ex
140 tion and K(ATP) channel opening is the major vasodilatory pathway for sildenafil in retinal arteriole
145 , when negated, allows for the expression of vasodilatory pathways which are masked by the primary ox
146 ular [Ca(2+)] regulate endothelium-dependent vasodilatory pathways, the molecular identities of the i
152 disease by using systemic overproduction of vasodilatory peptides, such as atrial natriuretic peptid
153 uces vasoconstriction through suppression of vasodilatory peptides, such as glucagon, or through a lo
155 P-loading greatly improved HDL signaling and vasodilatory potential in pre-contracted arteries and co
157 Inhibition of eNOS reduces synthesis of its vasodilatory product, nitric oxide, leading to arterial
158 have several roles in skin-e.g., pro-edema, vasodilatory, proinflammatory, and pruritogenic-melatoni
159 S-nitrosation of Hb (SNO-Hb) may confer vasodilatory properties by allowing release of NO during
161 fat diet combining the anti-inflammatory and vasodilatory properties of eicosapentaenoic acid (EPA; f
162 enalaprilat, verapamil, and caffeine on the vasodilatory properties of the adenosine A(2A)-receptor
163 erent assays to evaluate the antioxidant and vasodilatory properties of three typical food products f
164 ts of cytochrome P450 epoxygenases that have vasodilatory properties similar to that of endothelium-d
166 omeric epoxyeicosatrienoic acids have potent vasodilatory properties while 20-hydroxyeicosatetraenoic
167 otential mechanisms include altered coronary vasodilatory properties, changes in regional mechanical
170 nner, was associated with an increase of the vasodilatory prostaglandin (PG) D2 in plasma and could b
173 e positioning, inhaled nitric oxide, inhaled vasodilatory prostaglandins, and extracorporeal membrane
175 ed rats was associated with incorporation of vasodilatory prostanoids in the renal-cell membrane and
180 n), there was a trend toward higher coronary vasodilatory reserve in men than in women (2.9 +/- 0.6 v
181 onary circulation and post-stenotic coronary vasodilatory reserve in patients with and without corona
183 y, severe coronary artery disease, decreased vasodilatory reserve of epicardial and resistance arteri
185 study was to assess the spectrum of coronary vasodilatory reserve values in patients with angiographi
186 There were no differences between coronary vasodilatory reserve values on the basis of gender for p
189 n consumed), peak VO2, total work performed, vasodilatory reserve, forearm mitochondrial oxidative fu
190 The measurement of post-stenotic coronary vasodilatory reserve, now possible in a large number of
193 hibition during exercise caused an immediate vasodilatory response (increase in Con(T) and Con(L) and
194 3] sigmoidal dose-response curve indicated a vasodilatory response as the concentration of the antago
195 s are obligatory to observe the normal local vasodilatory response from rest to SS hypoxia; (2) NO re
197 o cardiac myocytes as well as modulating the vasodilatory response mediated by endothelial nitric oxi
198 es can damage the endothelium and impair the vasodilatory response of arteries; however, there are no
203 , there was no age-related difference in the vasodilatory response to acetylcholine among the enduran
204 d hypercoagulability, and restoration of the vasodilatory response to acetylcholine to levels compara
206 rats exposed to CIH exhibited an attenuated vasodilatory response to ACh and hyperresponse to Mtx co
208 xation is increased; (4) L-NAME suppressible vasodilatory response to ET is abolished; (5) there is n
209 e observed impairments in ACh responses, the vasodilatory response to exogenous ATP is not reduced wi
211 y is depleted in banked blood, impairing the vasodilatory response to hypoxia, and they suggest that
216 52.3 +/- 1.1% (P < 0.001) and inhibited the vasodilatory response to NF023 (50 mum, 7.9 +/- 2.0%; P
218 e to the upright-seated posture augments the vasodilatory response to PLM in the young, with no effec
225 ogs produced vasodilation, whereas a similar vasodilatory response was observed during exercise in CH
226 essure and both the immediate and peak rapid vasodilatory response, such that the responses increased
227 e vascular endothelial nitric oxide synthase vasodilatory response, which is a common potential site
236 nize the effects of endothelin-1, it induced vasodilatory responses leading to a significant improvem
239 lower apoA-I levels also displayed impaired vasodilatory responses to acetylcholine (mean +/- SEM, 1
240 explains how vascular XO activity diminishes vasodilatory responses to acetylcholine in hypercholeste
242 17-ODYA interventions, respectively) mediate vasodilatory responses to ACh but not to KCl, and that v
245 B) receptor mediated, nitric oxide dependent vasodilatory responses to ET-1 compared with controls an
246 ased ipsilateral, but not contralateral, UBF vasodilatory responses to exogenous E2beta by approximat
247 d whites exhibited comparable myocardial and vasodilatory responses to heat stress, but blacks exhibi
248 blocker, BaCl(2) (30 micromol/L), inhibited vasodilatory responses to KCl and bradykinin but not to
249 lts indicate that relaxin mediates the renal vasodilatory responses to pregnancy and thus may be impo
252 pothesis that muscle fatigue would attenuate vasodilatory responsiveness throughout the resistance ne
253 2) the COX pathway does not appear to have a vasodilatory role in cutaneous reactive hyperaemia.
254 e blood-pressure-lowering effects of the new vasodilatory, selective endothelin type A antagonist, da
256 the well-described vasopressin deficiency in vasodilatory septic shock, these studies indicate that d
263 device (n=23) were evaluated for post-bypass vasodilatory shock requiring catecholamine pressors, and
264 at our institution have studied a variety of vasodilatory shock states that are characterized by vaso
267 ly increased blood pressure in patients with vasodilatory shock that did not respond to high doses of
270 sin plasma levels are inappropriately low in vasodilatory shock, most likely because of impaired baro
271 y of vasopressin has been found in prolonged vasodilatory shock, such as is seen in severe sepsis.
275 GS5 may balance vascular tone by attenuating vasodilatory signaling in vivo in opposition to RGS2, an
277 egulate blood pressure by releasing ATP as a vasodilatory signaling molecule in response to the incre
278 (.)); however, the effects of aldosterone on vasodilatory signaling pathways in vascular smooth muscl
280 sient receptor vanilloid 4 (TRPV4) channel's vasodilatory signaling using mathematical modeling.
281 hesis that stimulating endothelium-dependent vasodilatory signalling will enhance the ability of cont
283 port the concept that EC Kir2 channels boost vasodilatory signals that are generated by Ca(2+) -depen
285 -nitro-L-arginine methyl ester, reverses the vasodilatory state, thereby improving fluid balance and
286 , and recently we observed that a variety of vasodilatory states are characterized by vasopressin def
287 trate were measured before and after a renal vasodilatory stimulus of a mixed amino acid intravenous
288 vel-dependent (BOLD) MRI in conjunction with vasodilatory stress to index the ability to augment intr
291 yte Ca2+ elevations can lead to secretion of vasodilatory substances from perivascular astrocyte endf
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