ライフサイエンスコーパス: vectorial

1 taneous intracellular sterol trafficking was vectorial.

2 and illustrate its essential role in normal vectorial acid transport into the urine by the kidney.

3 antly, this myosin II-derived force inhibits vectorial actin polymerization at focal adhesions throug

4 ort the hypothesis that fatty acid import by vectorial acylation in yeast requires a multiprotein com

5 of exogenous fatty acids by a process called vectorial acylation.

6 Vectorial analyses were conducted in accordance with the

7 s rate-limiting step is then followed by the vectorial and sequential folding of the remaining repeat

8 ls, produced by TLC-S application, displayed vectorial apical-to-basal polarity.

9 ymal interactions with the UB seem to govern vectorial arborization and tapering of the collecting sy

10 a methodology that can be used to visualize vectorial auxin responses in a manner that can be integr

11 se studies provide evidence for a regulated, vectorial, basolateral-to-apical bicarbonate transport i

12 can be used to produce a radially polarized vectorial beam for optical needle field generation.

13 Annexin bridging is vectorial, because annexin is bound to PS molecules on t

14 amatic pathological sequelae nor impairs the vectorial behavior or lifespan, indicating that mosquito

15 Net and vectorial beta-hexosaminidase secretion, cytosolic Ca(2+

16 % efficiency, although most probably without vectorial bias.

17 ondary structures may contribute to impaired vectorial bile duct secretion and postischemic cholestas

18 The established cell line displayed vectorial bile salt transport and specific phosphatidylc

19 Vectorial biotinylation detected apically disposed, cell

20 ing flow cytometry, confocal microscopy, and vectorial biotinylation.

21 portantly, other functions of seipin, namely vectorial budding and resistance to inositol, are retain

22 also demonstrate that seipin is required for vectorial budding of droplets toward the cytoplasm.

23 his result is consistent with the concept of vectorial Ca2+ efflux in which Ca2+ pumping by SERCA red

24 stimulates both cellular calcium uptake and vectorial calcium transport activities in Rcho-1 cells.

25 pecies' invasiveness, vector competence, and vectorial capacity (VC).

26 We report on three components of vectorial capacity - vector competency, distributional a

27 To investigate the genomic basis of vectorial capacity and explore new avenues for vector co

28 level analogues of two classical quantities: vectorial capacity and the basic reproductive number, R0

29 However, the robustness of the vectorial capacity approach is challenged by the fact th

30 ses of 3 degrees C from 27 degrees C reduced vectorial capacity by 51-89% depending on species and DT

31 ty, and mosquito mortality decreased overall vectorial capacity for both mosquito species.

32 Variation in vectorial capacity for human malaria among Anopheles mos

33 Its rapid expansion and vectorial capacity for various arboviruses affect an inc

34 he phylogenetic history and the evolution of vectorial capacity in the A. gambiae complex.

35 Genetic manipulation of mosquito vectorial capacity is a promising new weapon for the con

36 A central component of its vectorial capacity is the ability to maintain sufficient

37 Our results suggest that traits enhancing vectorial capacity may be gained through interspecific g

38 ing a framework based on measurements of the vectorial capacity of an insect population to transmit d

39 Genetic modification of the vectorial capacity of mosquito vectors of human disease

40 pathogen's genome may be used to reduce the vectorial capacity of mosquitoes for that virus.

41 function of Anopheles genes determining the vectorial capacity of the malaria parasite.

42 thways to biological processes essential for vectorial capacity such as fertility, locomotion and sur

43 we show that a low observation rate and high vectorial capacity translated into a significant attack

44 south, our estimates suggest an increase in vectorial capacity under all scenarios.

45 st that in the desert fringes of the Sahara, vectorial capacity would increase under the worst-case s

46 culation models (GCMs) to predict changes in vectorial capacity, an indication of the risk of human m

47 pecies, these phenotypic differences include vectorial capacity, as it is only females that blood fee

48 of memory on vector behaviour, particularly vectorial capacity, has barely been investigated.

49 Some determinants of vectorial capacity, such as chemosensory genes, do not s

50 vector species worldwide and key elements of vectorial capacity, we review the sensitivity of Culicoi

51 n host-seeking behaviors that underlie their vectorial capacity.

52 opulations of genetic constructs that reduce vectorial capacity.

53 les gambiae, where olfaction is critical for vectorial capacity.

54 ecological differentiation, speciation, and vectorial capacity.

55 egy for the genetic manipulation of mosquito vectorial capacity.

56 n, we first use a standard model of relative vectorial capacity.

57 al and fecundity, which are known to augment vectorial capacity.

58 e physiological processes intimately tied to vectorial capacity.

59 hel, climate change is predicted to decrease vectorial capacity.

60 odified microtubules are oriented to support vectorial cargo transport to areas of high need.

61 on transport across membranes in microalgae (vectorial catalysis).

62 itical for numerous processes, including the vectorial cell migration required for wound healing, cel

63 enable to the specific investigation of this vectorial cellular communication.

64 also generating functional switches to drive vectorial cellular processes.

65 The ramifications of vectorial charge redistribution are discussed in the con

66 This ultrafast vectorial charge-transfer process illustrates the potent

67 These enzymes each catalyse two vectorial/chemical reactions, sugar phosphorylation usin

68 bR), the luminally derived adenosine induces vectorial chloride secretion and a polarized secretion o

69 t 10% of CFTR mutations, result in defective vectorial chloride transport, partly by altering the pol

70 membrane in epithelial cells is critical for vectorial chloride transport.

71 PPARdelta coordinate NPC1L1/ABCA1-dependent vectorial cholesterol flux from bile through cholangiocy

72 decreases by 50% beta2AR agonist-stimulated vectorial Cl(-) and net fluid transport across rat and h

73 formate exchange protein that represents the vectorial component of a proton-motive metabolic cycle i

74 ric spatial reference frames and may involve vectorial computations relative to landmarks.

75 [corrected] How do such vectorial constraints impact the folding pathway?

76 mperature, operating in conjunction with the vectorial control of crystal growth.

77 in occurs prior to their exit and subsequent vectorial cotransport on post-Golgi vesicles to ROS.

78 (exchange) = 1.4 +/- 0.2), establishing that vectorial delivery of copper by Atx1 is not based on a h

79 astigmatism measurements was defined as the vectorial difference with the refractive astigmatism, wi

80 paradigm wherein a cellular ligand promotes vectorial domain folding by facilitating an energeticall

81 nd the molecular principles that provide the vectorial driving force of these interactions, we develo

82 n; Overall dynamic body acceleration (ODBA), vectorial dynamic body acceleration (VDBA), acceleration

83 sfer events and therefore contributes to the vectorial efficiency of proton transport.

84 on-the dispersion relation of the underlying vectorial electromagnetic modes-by their selective excit

85 omplexes would be of practical importance in vectorial electron and/or electron transfer in various o

86 residue relative to the flavin for efficient vectorial electron transfer leading to photoreduction.

87 The polypeptide's vectorial emergence from the ribosomal tunnel establishe

88 nsport measurements because of the lack of a vectorial environment and necessitating reconstitution i

89 oyl-CoA synthetase activity, which indicates vectorial esterification and metabolic trapping are the

90 ET is not just an inevitable consequence of vectorial ET with small energetic offsets, but is in fac

91 r models of minicircle replication involving vectorial export of free minicircles into the KFZ.

92 This protein plays an important role in vectorial fatty acid transport across the plasma membran

93 xtend the super-oscillation concept into the vectorial-field regime to work with circularly polarized

94 solutes were loaded by the PCE cells, then a vectorial flow from the blood into the eye would occur.

95 Vectorial flow of zebrafish aqueous humor is in contrast

96 ta(2)-adrenergic receptor agonist-stimulated vectorial fluid and Cl(-) transport across primary rat a

97 that were associated with a decrease in net vectorial fluid transport across human alveolar type II

98 Inhibition of cAMP-dependent stimulation of vectorial fluid transport across the alveolar epithelium

99 ibition of cAMP-dependent stimulation of the vectorial fluid transport across the lung epithelium fol

100 ssion of ion transport genes responsible for vectorial fluid transport in primary cultures of human a

101 re of the alveolar epithelium to up-regulate vectorial fluid transport in response to beta-adrenergic

102 Functional studies demonstrated that net vectorial fluid transport was reduced for human alveolar

103 of epithelial electrogenic Cl- secretion and vectorial fluid transport.

104 uggesting that the M4 helix rotates to allow vectorial flux of Ca2+ upon enzyme phosphorylation.

105 These results challenge the vectorial folding model and, together with the finding t

106 f native protein during OM secretion; hence, vectorial folding of the beta-helix could contribute to

107 The prevailing model postulates that vectorial folding of the beta-helix in the extracellular

108 passenger moves, with the energy provided by vectorial folding of the beta-strand-rich passenger on t

109 Because the periplasm lacks ATP, vectorial folding of the passenger domain in a C-to-N-te

110 ps and led to the full reconstruction of the vectorial folding pathway of a large polypeptide, the 25

111 Given that most membrane proteins have vectorial functions, both functional studies and applica

112 Vectorial imaging of magnetic domains reveals an unusual

113 ese data suggested that the presence of anti-vectorial immunity impacts the rate of differentiation o

114 In this study, we used models of anti-vectorial immunity to investigate the impact of pre-exis

115 arized epithelial cells contribute important vectorial information for guidance of young, migrating n

116 nals alone are insufficient, and to use that vectorial information to bias movement by enhancing the

117 indicating that both native conformation and vectorial insertion were accomplished.

118 erm in the objective function that penalizes vectorial invariants of the reconstructed surface stress

119 we hypothesized that IL-1beta would decrease vectorial ion and water transport across the distal lung

120 othesized that TGF-beta1 would also decrease vectorial ion and water transport across the distal lung

121 We reconstituted a model vectorial ion pump, proteorhodopsin, in liposomes of opp

122 PSTI also induced changes in vectorial ion transport (short-circuit current) when add

123 Restitution and vectorial ion transport effects of PSTI were dependent o

124 link between the structural organization and vectorial ion transport function of epithelial cells.

125 ich cells (MRCs) indicates that they mediate vectorial ion transport.

126 cells are reproducibly detectable following vectorial labelling with biotin, and that detailed analy

127 kine receptor agonist can inhibit the normal vectorial leukocyte migration mediated by chemokines.

128 model for structural changes involved in the vectorial, light-driven transport of protons by bacterio

129 holangiocytes then transport bile acids in a vectorial manner across their apical and basolateral pla

130 e remarkable ability to translocate DNA in a vectorial manner, orienting themselves according to pola

131 Here we use time-resolved-vectorial measurements of magnetization dynamics of thin

132 This preferential, vectorial migration was chemotactic toward many differen

133 cell (DC) showed chemoattractantDeltadriven vectorial migration, while CD8 T cell migration across L

134 e chemistries to one another, rather than to vectorial motion.

135 ion of bile flow and is rate limiting in the vectorial movement of bile acids from blood to bile.

136 The vectorial movement of proteins requires specific recogni

137 - and outward-facing conformations, allowing vectorial movement of substrates.

138 g axons and determining whether they undergo vectorial movement.

139 The vectorial (N- to C-terminal) nature of cotranslational f

140 d polarity of transport proteins involved in vectorial Na movement in ARPKD epithelium.

141 However, vectorial Na(+) transport across confluent monolayers of

142 ncreases lung edema clearance by stimulating vectorial Na+ flux and Na, K-ATPase function in rat alve

143 l properties of the nascent polypeptide, the vectorial nature and rate of translation, molecular crow

144 ct N-terminal nucleus is consistent with the vectorial nature of cotranslational membrane insertion f

145 entation, and functional assays verified the vectorial nature of ion transport in this system.

146 otranslational folding is complicated by the vectorial nature of nascent chains, the frequent ribosom

147 cclusion to its dephosphorylation ensure the vectorial nature of net transport.

148 A 'switch' mechanism ensures the vectorial nature of pumping.

149 Given the vectorial nature of ribosome-assisted translation, the t

150 data track or that make explicit use of the vectorial nature of the data are not applicable in such

151 location of pinwheel centers because of the vectorial nature of these patterns, such that the appare

152 Numerical simulations based on the vectorial nonlinear Schr odinger equation demonstrate a

153 -2 is uniformly distributed, arguing against vectorial nuclear export into the mitochondrial cloud.

154 lizing pair-rule transcripts by directional (vectorial) nuclear export.

155 s traditional MANOVA tests commonly used for vectorial observations.

156 lcium responses of fibroblast cells, using a vectorial, or multi-time-point, measure from information

157 rizzled (Fz)/PCP signaling regulates planar, vectorial orientation of cells or groups of cells within

158 The profile structures established the vectorial orientation of the Ca(2+)-ATPase within these

159 ing a membrane protein with a unidirectional vectorial orientation, on a semiinfinite aqueous subphas

160 initial Luciferase refolding occurs along a vectorial pathway and also suggest a mechanism that chap

161 ere used to construct a working model of the vectorial pathway for the translocation of taurine acros

162 te repression in addition to its role in the vectorial phosphorylation of glucose catalyzed by the ph

163 Our approach allows for a fine vectorial picture of the local forces gating the channel

164 r the structure of the complex by exploiting vectorial preparation methods and manipulating ionic str

165 Axonal autophagy is a vectorial process that delivers cargo from the distal ax

166 strate-stimulated ATP hydrolysis by Pgp is a vectorial process.

167 that control cell survival, cell growth, and vectorial processes including protein targeting in polar

168 action between the C-propeptides followed by vectorial propagation of the triple-helical domain in th

169 e non-autonomous effects on cell polarity, a vectorial property.

170 Based on vectorial proteolysis of right-side-out vesicles with tr

171 the two carboxylate residues that define the vectorial proton path in BR in which Asp-85 and Asp-96 s

172 involving the same residues that define the vectorial proton path in BR.

173 ts of water and protein atoms that result in vectorial proton transfers to and from the Schiff base.

174 the earlier protonated acceptor, preventing vectorial proton translocation across the membrane.

175 hile not ruled out, is not required and that vectorial proton transport can be achieved through the c

176 To enforce vectorial proton transport in bacteriorhodopsin (bR), it

177 collecting duct of the distal nephron, where vectorial proton transport is required for urinary acidi

178 n as the "reprotonation switch" required for vectorial proton transport.

179 te dissociation of Kap60p.NLS complexes in a vectorial reaction mechanism.

180 egments so that neither the chemical nor the vectorial reaction will be completed unless the other is

181 pecificity for catalysis of the chemical and vectorial reactions.

182 uction and its translocation to the nucleus, vectorial release of PGs, and mitogenesis in polarized H

183 r) filters to study COX-2 production and the vectorial release of prostaglandins (PGs).

184 landin E2 (PGE2) release, a process we call "vectorial release via sided reuptake." Importantly, alth

185 eins are sorted in the TGN into at least two vectorial routes to apical and basolateral surface domai

186 veolar fluid clearance is mainly governed by vectorial salt movement via apically located rate-limiti

187 significantly to bile formation through the vectorial secretion of water and electrolytes and are a

188 secretion, including a concerted process, or vectorial secretion with different directionalities.

189 on within the SNARE complex does not support vectorial SNARE complex zipping during exocytosis.

190 ned by sequence-independent interactions and vectorial-specific recognition domains.

191 e of unsterile pH probes and endoscopes, and vectorial spread by flies.

192 to calcify appears to involve a block of the vectorial spread of mineral from initial nuclei within M

193 involving transient assembly and short-range vectorial spurts.

194 through a series of alternating chemical and vectorial steps that involve a series of changes in the

195 These enzymes are able to generate vectorial strand transport independent of the supercoili

196 dvances during propagation, we show that the vectorial structure of the near field of an emitter is e

197 ion of inorganic sulfur from thiosulfate and vectorial sulfur transfer, and we designate NWMN_0026.5

198 water transport into the airway lumen is the vectorial sum of the water fluxes associated with active

199 Thus, a vectorial summation to derive DBA cannot be assumed to b

200 es are observed to exhibit three-dimensional vectorial textures, which collectively feature a chirali

201 argeted in polarized cell types that mediate vectorial thiamine transport (e.g. renal and intestinal

202 acids, a motif that plays a pivotal role in vectorial trafficking in polarized epithelial cells and

203 e, but our mechanistic understanding of this vectorial trafficking step in plants is limited.

204 In both cell lines, vectorial transepithelial apparent permeability coeffici

205 ork in a concerted manner to bring about the vectorial transfer of folate across the RPE cell layer f

206 monstrate the importance of ferritin for the vectorial transfer of imported iron to mitochondria in d

207 RPE cells mediate the vectorial transfer of nutrients from choroidal blood to

208 y of cargo complexes followed by short-range vectorial transit (the "dynamic recruitment" model).

209 site is involved directly in the process of vectorial translocation of arsenite or antimonite across

210 ulate and undergo uncoupled cleavage, before vectorial translocation of bound Ca(2+) in the forward d

211 Vectorial translocation of FGF2 across the membrane is g

212 ad-to-tail consistent with a cooperative and vectorial translocation of protein substrates.

213 udy of the utilization of binding energy for vectorial translocation of protons and other cations.

214 n along the free-energy surface results in a vectorial translocation of the DNA, consistent with the

215 of YopB, which in turn is essential for the vectorial translocation of Yops into eukaryotic cells.

216 of the chronic disease in smaller scale than vectorial transmission, reported as controlled in countr

217 t GFP-tagged sensory receptors undergo rapid vectorial transport along the entire length of the cilia

218 rans-Golgi network (TGN) are involved in the vectorial transport and delivery of rhodopsin to photore

219 ysosomes, suggesting that ARD1 might undergo vectorial transport between the two organelles.

220 We studied the vectorial transport characteristics of indinavir, nelfin

221 has been established to be essential to the vectorial transport efficiency of CcO, yet the underlyin

222 basolateral membrane, respectively, allowing vectorial transport in both directions depending on the

223 stinct structural elements that cooperate in vectorial transport in polarized epithelial cells.

224 -NFH-labeled neurofilaments undergo vigorous vectorial transport in the axon in both anterograde and

225 ely on the basolateral membrane and mediates vectorial transport of bicarbonate in a number of epithe

226 In retinal photoreceptors, vectorial transport of cargo is critical for transductio

227 membrane of epithelial cells is critical for vectorial transport of chloride in a variety of epitheli

228 hypothesize that the RPE plays a role in the vectorial transport of folate from the choroidal blood t

229 r with the reduced-folate transporter in the vectorial transport of folate from the choroidal blood t

230 The role of these transporters in the vectorial transport of folates across epithelia is consi

231 able, nonpolymerizable actin mutant, we show vectorial transport of G-actin in live migrating endothe

232 e, a ubiquitous membrane protein critical to vectorial transport of ions and nutrients, is required t

233 ted a role for the actin cytoskeleton in the vectorial transport of late secretory vesicles to the pl

234 It is hypothesized that Ran drives vectorial transport of macromolecules into and out of th

235 Surprisingly, TRAP also stimulates vectorial transport of many, but not all, other substrat

236 consistent with previous experiments showing vectorial transport of organic anions between the choroi

237 Precise vectorial transport of rhodopsin is essential for rod ph

238 microtubules led to a dramatic inhibition of vectorial transport of SCb cargoes.

239 directional permeation of anions rather than vectorial transport of solutes.

240 ement of transmembrane domains necessary for vectorial transport of substrates in ATP-binding cassett

241 e effect of [K+]o trans-RPF gradients on the vectorial transport of taurine across the isolated prepa

242 retrograde transport as part of a program of vectorial transport of the viral genome to the nucleus.

243 retrograde transport as part of a program of vectorial transport of viral genome to the nucleus.

244 dium pump (Na+, K+, ATPase) resulting in the vectorial transport of water into the blastocoel.

245 To examine vectorial transport properties of Tat basic domain in we

246 action, we characterized the biochemical and vectorial transport properties of this protein.

247 d the N- and O-glycosylation sites, retained vectorial transport to apical membranes.

248 e show that MEX-5 asymmetry requires neither vectorial transport to the anterior, nor protein degrada

249 m the trans-Golgi network (TGN) and by their vectorial transport toward the rod outer segment.

250 that this ATPase activity is not coupled to vectorial transport, including 1) NOD does not produce m

251 osomes to microtubules rather than producing vectorial transport.

252 bound form of Ran/TC4 with NTF2 helps define vectorial transport.

253 e largely irreversible steps associated with vectorial transport.

254 g, nanopore pulling assay for dissecting the vectorial unfolding mechanism of pseudoknots.

255 These findings provide new insights into RNA vectorial unfolding mechanisms, which play an important

256 te- and strand-specific fashion, and mediate vectorial unwinding of the DNA duplex via an ATP-depende

257 totypic signaling system responsible for the vectorial uptake and phosphorylation of carbohydrate sub

258 This vectorial vortex analysis enables a determination of the

259 Vectorial vortex analysis is used to determine the polar

260 Polarized THz beams are converted into THz vectorial vortex beams with no spatial or wavelength dis

261 THz beam but can also passively control THz vectorial vortex beams.

262 is void of aquaporins adept at facilitating vectorial water transport, and yet it reabsorbs approxim

263 ding energy to the kinetic power stroke of a vectorial zinc transport.