ライフサイエンスコーパス: venous valve

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1 lantation, and confirmed Prox1 expression in venous valves.

2 aling for the development and maintenance of venous valves.

3 and in the atrioventricular, semilunar, and venous valves.

4 itical for the development or maintenance of venous valves.

5 Intriguingly, developing and mature venous valves also expressed a repertoire of proteins, i

6 ecame preferentially localized to the dorsal venous valve and atrioventricular canal regions.

7 ptum, display dilated atria with hypoplastic venous valves, and exhibit blood backflow from the heart

8 ion, fusion with the inferior margins of the venous valves, and formation of the mouth of the coronar

9 ions are not well understood, but congenital venous valve aplasia or agenesis may play a role in some

10 reover, we show that in Cx37-deficient mice, venous valves are entirely absent.

11 Deep venous valves are frequent sites of deep venous thrombos

12 therefore identified molecular regulators of venous valve development and maintenance and highlighted

13 eads to severe hypoplasia of the SAN and the venous valves, dis-regulation of the SAN genetic network

14 Unexpectedly, we found that venous valve endothelial cells closely resemble lymphati

15 thesis that FOXC2 mutations may be linked to venous valve failure and reflux.

16 s have been strongly associated with primary venous valve failure in both the superficial and deep ve

17 regulating the formation and maintenance of venous valves have not been studied.

18 e (reflux), and FOXC2 is highly expressed on venous valves in mouse embryos, we tested the hypothesis

19 This review focuses on the role of the venous valves in the genesis of thrombus formation in ve

20 at we believe to be the first description of venous valve morphogenesis and identify signaling pathwa

21 Venous valves play a crucial role in blood circulation,

22 ntrolling the development and maintenance of venous valves remain poorly understood.

23 Using global and venous valve-selective knockout mice, we further demonst

24 By preventing retrograde flow, venous valves spare capillaries and venules from being s

25 Venous valves (VVs) prevent venous hypertension and ulce

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