ライフサイエンスコーパス: versatile

1 lso prepared in two- to three-steps from the versatile 2-hydroxy-5,6,7,7a-tetrahydro-3H-pyrrolizin-3-

2 possible to access all four stereoisomers of versatile 2-vinyltetrahydrofurans with exceedingly high

3 Synthetically versatile 3,3-disubstituted fluorooxindoles exhibiting v

4 This new route provides straightforward and versatile access to drug-relevant scaffolds or fragments

5 Given that the products are versatile, accessing polyfluorinated arene building bloc

6 This work describes a versatile analytical approach, which combines the proxy

7 ue or salience, the signal appears to play a versatile and active role in adaptive sensorimotor prior

8 Polypyridyl platforms have proven quite versatile and amenable to studying various parameters th

9 This approach is very versatile and can be applied to produce ternary and quat

10 y-based electrocatalytic sensing strategy is versatile and can potentially be used with other folding

11 requency conversion of photons which is both versatile and deterministic.

12 ze a single locus, we have built a flexible, versatile and easy-to-use web interface designed to help

13 ld comprise a more environmentally-friendly, versatile and economical alternative.

14 The small animal tumor model is the most versatile and effective means of understanding tumor tra

15 The reaction is highly versatile and exhibits good functional group tolerance w

16 Messenger RNA (mRNA) has emerged as a versatile and highly effective platform to deliver vacci

17 nd efficient optoelectronic devices based on versatile and inexpensive solution-processable materials

18 ngle mode fiber, making this approach highly versatile and integrable.

19 The design and fabrication of a versatile and low-cost electrochemical-scanning probe mi

20 sable materials in order to generate simple, versatile and low-cost microfluidic devices.

21 S4s without modifications, demonstrating the versatile and modular nature of S4s.

22 ate characterization, and the development of versatile and permissive culture systems.

23 ine, and chemistry, indicating the extremely versatile and polyedric aspect of this nanomaterial.

24 acetylated linear polyglucosamines, are very versatile and promising functional biopolymers.

25 cific antibodies (bsAbs) are one of the most versatile and promising pharmaceutical innovations for c

26 A versatile and rapid access to various chain lengths of e

27 roducts obtained in this reaction are highly versatile and rapidly undergo further diversification.

28 functional peptides would therefore offer a versatile and robust platform to produce highly function

29 The proposed protocol provides a versatile and scalable alternative to existing routes fo

30 Glycodendrimersomes provide a versatile and sensitive diagnostic platform to reveal th

31 oF mass spectrometry was introduced as a new versatile and sensitive tool to investigate covalently f

32 novel biointerfaces led to exploit the more versatile and tunable graphene-like 2D nanomaterials (e.

33 Cystatin C (CysC) is a versatile and ubiquitously-expressed member of the cyste

34 HF (SmI2(H2O)n) has in recent years become a versatile and useful reagent, mainly for reducing carbon

35 dimensional (3D) printing has proven to be a versatile and useful technology for specialized applicat

36 orm Caenorhabditis elegans (C. elegans) is a versatile and widely used animal model for in vivo studi

37 as the "in vitro scratch assay" as a simple, versatile, and cost-effective method to study collective

38 Since APEX-RIP is simple, versatile, and does not require special instrumentation,

39 m represents a new class of easily prepared, versatile, and redox-active oxido clusters that should c

40 of injectable hydrogels and summarizes their versatile application in the treatment of ophthalmic dis

41 ion with no chemical mediators, represents a versatile approach for detection of a wide variety of ot

42 lity through structure-directing agents is a versatile approach for new materials synthesis that has

43 he galvanic replacement reaction is a highly versatile approach for the creation of a variety of nano

44 In this study, we demonstrate a versatile approach for the formation of electrochromic n

45 rlying mathematical tool, has proven to be a versatile approach to achieve such unusual outcomes rely

46 Herein we show a versatile approach to control the buckling of individual

47 ticles with polymer ligands has emerged as a versatile approach to control the interactions and organ

48 In a new, versatile approach to fun-ction-alizing recombinant spid

49 tion (ALD) in MOFs has recently emerged as a versatile approach to functionalize MOF surfaces with a

50 ions, CD8alpha:MyD88 represents a unique and versatile approach to help overcome immunosuppression an

51 This bottom-up strategy offers a versatile approach to the rational design of strongly co

52 chemistry tailoring with SAMs constitutes a versatile approach towards the tuning of the electronic

53 all, we show that this is an informative and versatile approach, suitable for exploring relationships

54 further endorsing the inorganic benzene as a versatile aromatic scaffold for engineering of molecular

55 A versatile array of nitrile oxides and alpha-keto esters

56 Furthermore, our strategy is extremely versatile, as solvent, nanoparticle and ligand can all b

57 We believe that the DNA sequence-directed versatile assembly of periodic higher-order structures r

58 s system, MyoRobot, for robust objective and versatile assessment of muscle or polymer materials (bio

59 Type IV secretion (T4S) systems are versatile bacterial secretion systems mediating transpor

60 Using the current fabrication technique, versatile bacteriorhodopsin-based photoelectric immunose

61 This versatile behavior might be a key feature for ecological

62 peed fluorescence microscopy illuminated the versatile behaviour of trypanosome developmental stages,

63 putational design and directed evolution are versatile biocatalysts whose promiscuous activities repr

64 g the whole-organism C. elegans coupled with versatile biochemical, biophysical, and genetic tools, w

65 This system provides a versatile biological tool to analyze human heart develop

66 graphene oxide (RGO) for the development of versatile biosensing platform.

67 , we demonstrate realization of a simple and versatile biosensor platform capable of high performance

68 This versatile biosensor platform simultaneously exploits the

69 Here, we establish a versatile blastocyst complementation platform based on C

70 on of widely available carboxylic acids into versatile boronic esters would be highly enabling for sy

71 A novel and versatile "bottom-up" approach is developed to estimate

72 red monofluorinated alkenes were shown to be versatile building blocks for the synthesis of various f

73 c labeling of Plasmodium mRNAs is incredibly versatile, can be used to measure transcriptional dynami

74 ste feeds, which currently underutilize this versatile carbon synthon.

75 These versatile catalysts are simple to prepare, easy to use,

76 deprotonation of ureas generates a class of versatile catalysts that are simultaneously fast and sel

77 mong organic azides, vinyl azides have shown versatile chemical reactivities in the recent developmen

78 cture, excellent mechanical performance, and versatile chemistry.

79 Triazole ureas constitute a versatile class of irreversible inhibitors that target s

80 es (heterocyclic nanographenes) are a highly versatile class of organic materials, applicable as func

81 The new role of the versatile cofactor SAM is likely to be found in other ex

82 A transcriptional regulators are emerging as versatile components for genetic network construction.

83 n numerous scientific fields as a simple and versatile conjugation strategy.

84 DNA is a versatile construction material for the bottom-up assemb

85 structure hierarchically assembled to form a versatile damage-tolerant protein-based tooth, with a st

86 A more versatile decoupling scheme, termed sel-SHARPER, removes

87 Higher polarizations, versatile detection schemes, and flow of (129)Xe over la

88 By harnessing such low-cost and versatile deuterated substrates, Raman-DIP has the poten

89 Our versatile device is an optimal platform for microfluidic

90 A simple and versatile directed assembly method of silk fibroin, whic

91 Here, we present a versatile DNA surface adapter that can programmably self

92 dance, organization, and function, combining versatile Drosophila genetics with superresolution micro

93 Here we discuss the history of this versatile drug and its use in global health.

94 erse reaction has the potential to allow the versatile E. coli system to be employed as an exciting n

95 Therefore, we envision the K-channel as a versatile, easy to use microfluidic component enabling d

96 A versatile, efficient, and metal-free method for construc

97 with much better air-stability, make PtSe2 a versatile electronic 2D layered material.

98 The genome encodes versatile energy pathways, including fermentative and re

99 e pharmaceutical industry are not precise or versatile enough for customized medicine formulation and

100 n vectors to mutagenize genes, and highlight versatile experimental strategies for the generation of

101 The versatile fabrication methods utilized in sensor develop

102 This study sheds light onto the versatile folding ability of the specific class of alpha

103 he dcFCCS framework presented here is highly versatile for biophysical analysis of binding interactio

104 Here we describe a rapid, simple and versatile Free-of-Acrylamide SDS-based Tissue Clearing (

105 Here we describe a versatile, functional pipeline and apply it to SNPs at 1

106 vidence also indicates that neutrophils have versatile functions in contributing to adaptive immunity

107 The versatile functions of SR (serine/arginine-rich) protein

108 Metarhizium robertsii is a versatile fungus with saprophytic, plant symbiotic and i

109 ly sensitive, miniaturized, easy-to-use, and versatile gas sensing.

110 CRISPR is a versatile gene editing tool which has revolutionized gen

111 ential of developing long-lasting, safe, and versatile gene therapy approaches based on engineering e

112 It is versatile, generating both conditional and targeted inse

113 system has been harnessed as a powerful and versatile genome-editing tool and holds immense promise

114 re remains the need, however, for a soluble, versatile, HBC-based platform, which can be tailored by

115 e "necessary nitrogen atom" is shown to be a versatile high-impact design element for multiparameter

116 scopy (FERS) is an arising new technique for versatile highly sensitive and selective multigas analys

117 -state (and chemically) specific, rapid, and versatile imaging technique for understanding and hence

118 Cardiac PET is a versatile imaging technique providing important diagnost

119 calcium sensor for photoacoustics (CaSPA), a versatile imaging technique that allows for fast volumet

120 ce of polar dielectric, allowing potentially versatile implementation in a host of materials such as

121 Despite its electron deficiency, boron is versatile in forming multiple bonds.

122 DNA origami is particularly versatile in this context because each DNA strand in the

123 five human RecQ proteins and is particularly versatile in this regard, forming protein complexes with

124 This procedure is operationally simple, versatile, inexpensive, and quick to perform, making it

125 ght the importance of diverse, flexible, and versatile inputs that shape network function.

126 cyclohexanones has been performed and yields versatile intermediates in high yields and enantioselect

127 Organic isocyanates are versatile intermediates that provide access to a wide ra

128 Chemical reaction networks (CRNs) are a versatile language for describing the dynamical behaviou

129 CBM64 compact structure and its extended and versatile ligand interacting platform illustrate how typ

130 tion or transesterification catalyzed by the versatile lipase/sterol esterase from the ascomycete fun

131 stepwise approach takes advantage of simple, versatile, low-cost screening tools that can be applied

132 eting growth is well known, conversely these versatile machines can also pull microscopic objects apa

133 The versatile manifestations of these highly contagious orga

134 re not matched by any other method, and this versatile material has the potential to bridge the perfo

135 dant in nature and they are some of the most versatile materials for applications ranging from cataly

136 Hydrogel particles are versatile materials that provide exquisite, tunable cont

137 ydrates in isotope-filtered experiments is a versatile means for a simultaneous mapping of the bindin

138 Alternatively, irradiation is a versatile means of evaluating defect interactions while

139 laments form different polymer networks with versatile mechanical properties that depend on their spa

140 signalling is perhaps the most universal and versatile mechanism regulating a wide range of cellular

141 s the power of selective catalysis to enable versatile membrane-free fuel cells.

142 ace properties highlights its potential as a versatile messenger in cell membrane events.

143 ready to use for various purposes due to the versatile metal complexation properties of the TPA unit.

144 ric acid-derived substrates should provide a versatile method for constructing useful building blocks

145 In conclusion, this versatile method is broadly applicable in screening and

146 Thus, the versatile method might become a potential alternative to

147 RP-ABPP thus provides a versatile method to monitor the metabolic regulation of

148 Here we report a simple and versatile method to transiently overexpress the hyaluron

149 Using this versatile method, that requires only single sided contac

150 Here, we present a versatile methodology to tackle this design issue by exp

151 Moreover, this efficient and versatile methodology, which also uses low-cost, "wet" r

152 ss spectrometry has afforded one of the most versatile methods to acquire structural information for

153 The development of a versatile microbiosensor for hydrogen detection is repor

154 These findings underpin a great potential of versatile microencapsulation technology for the developm

155 ic cleavage, while the phosphonyl group is a versatile mimic of transition-states, intermediates, and

156 vers of arsenic methylation in metabolically versatile mixed anaerobic enrichments from a Mekong Delt

157 We have demonstrated a versatile mode matching method for FFPCs.

158 ithelium and human neutrophils can provide a versatile model of trans-epithelial migration in vitro,

159 , are demonstrating that ubiquitylation is a versatile modification that can be used to fine-tune the

160 We now identify versatile modifications at Lys31 within the globular dom

161 d in living organisms and is one of the most versatile molecules in metabolism.

162 lncRNAs are remarkably versatile molecules that interact with RNA, DNA, or prot

163 s the potential therapeutic utility of these versatile molecules.

164 The imine partner bears the synthetically versatile N-Cbz group, avoiding the use of the specializ

165 Cytochrome P450-reductase (CPR) is a versatile NADPH-dependent electron donor located in the

166 old to upconversion nanoparticles, a simple, versatile nanoparticulate system for simultaneous deep-t

167 Thus, this simple and versatile nanoplatform has great potential for the selec

168 The versatile nature of GMs may be explored to enable multi-

169 The performance capabilities of this versatile new arrangement were demonstrated for differen

170 Our results reveal a versatile new family of tunable materials with excellent

171 In the past 15 years, versatile new methods have been developed that effect cr

172 The versatile new poly(oligo(ethylene glycol) vinyl acetate)

173 ConcatSeq provides a versatile new sample preparation tool for long-read sequ

174 ative magnetic resonance imaging (qMRI) is a versatile, non-destructive and non-invasive tool in life

175 ivation has enabled facile installation of a versatile, nucleophilic coupling handle at a previously

176 We have developed a versatile on-chip vortex-assisted electroporation system

177 Here, we introduce plantiSMASH, a versatile online analysis platform that automates the id

178 ology, but current solutions are costly, not versatile or are difficult to deploy.

179 tching the size of methylene blue (MB(+)), a versatile organic molecule used for bio-recognition, was

180 truction of carbocyclic ring systems bearing versatile organoboronic esters.

181 -oriented synthesis (DOS) is achieved with a versatile oxalyl linker offering rapid access to complex

182 Here, we demonstrate a versatile partial cation exchange method to fabricate la

183 A novel and versatile peptide-based bio-logic system capable of regu

184 In recent years, numerous versatile peptidic catalysts have been developed that be

185 elets, which imply a single subpopulation of versatile platelets and thus suggest that their commonal

186 This highly versatile platform employs mass spectrometry and statist

187 m cells (piPSC) in vitro thereby providing a versatile platform for applications ranging from regener

188 mi, in combination with GFP antibodies, is a versatile platform for calibrating fluorophore and antib

189 synthetic approach constitutes a simple and versatile platform for expanding the availability of tai

190 otected by crystalline symmetry, which are a versatile platform for exploring topological phenomena a

191 Myristoylated ELPs provide a versatile platform for genetically pre-programming self-

192 Thus, the MGNT arrays may be used as a versatile platform for high-sensitive label-free optical

193 ed moieties makes the avidin-biotin system a versatile platform for nanotechnology.

194 rks and tunable surface chemistries, offer a versatile platform for preparing well-defined nanostruct

195 Double quantum dots (DQDs) are a versatile platform for solid-state physics, quantum comp

196 alysis by LILBID mass spectrometry provide a versatile platform for the analysis of membrane proteins

197 ges of using rLDL particles as a natural and versatile platform for the targeted delivery of theranos

198 This versatile platform is applicable to study a wide range o

199 ning metal-organic framework (MOF) confers a versatile platform to contrive next-generation chemical

200 nitrogen-heteroatom bonds as a powerful and versatile platform to rapidly synthesize diverse aminoar

201 Here, we demonstrate a versatile platform to realize 1D systems made by combini

202 atial addressability, DNA origami provides a versatile platform with which to engineer nanoscale stru

203 These advances with versatile, preassembled reagents could greatly reduce th

204 unfold possibilities for more efficient and versatile production of 3D objects.

205 ormation of a diverse range of synthetically versatile products from simple precursors.

206 ed from colloidal nanomaterials give rise to versatile properties that can be exploited in a range of

207 The versatile protein assembly mechanism conferred by the ba

208 ch guanidinium salts can act as powerful and versatile protein denaturants.

209 e propose that CrPV-1A is a multifunctional, versatile protein that creates a cellular environment in

210 The highly motile and versatile protozoan pathogen Trypanosoma brucei undergoe

211 The simple and versatile qRAS design offers a useful tool for the inves

212 opens the door to the use of molecules as a versatile quantum memory and for precision measurements

213 reaction is now one of the fastest and most versatile reactions available for conjugations of biomol

214 utilization of fluorinated sulfur ylides as versatile reagents for Corey-Chaykovsky cyclopropanation

215 noldiazo esters and amides have proven to be versatile reagents for cycloaddition reactions that allo

216 ever, the neural mechanism to construct such versatile receptive fields remains unclear.

217 that in demanding building blocks with more versatile redox chemistry, biospheric molecular oxygen t

218 carbon organic radical great potential as a versatile reducing agent that can be generalized in othe

219 found that CH4 was a highly efficient and a versatile reducing agent, as the total reducing power of

220 It also positions the versatile regulator Gle1 as a potential node for the coo

221 tion, and that ITIM-containing receptors are versatile regulators of platelet signal transduction, wi

222 Thus, pneumococci express a versatile repertoire of surface proteins sequestering an

223 Finally, we used the versatile RESA platform to map candidate protein-RNA int

224 rize complex cellular networks and provide a versatile resource to identify new regulators of mitocho

225 ps and a regulator of RNaseH1, extending the versatile role of RPA in suppression of genomic instabil

226 A-binding domain in eukaryotes, and it plays versatile roles in RNA metabolism.

227 A versatile Rotary Chemical Vapour Deposition (RCVD) techn

228 Here we report a versatile S-adenosyl-l-methionine (SAM)-dependent enzyme

229 1,2,4-triazolo[4,3-a]pyrazin-3-one as a new versatile scaffold for the development of adenosine huma

230 the human adaptive immune system, providing versatile scaffolds to display diverse antigen-binding s

231 These successful predictions of the versatile SCAN functional open the gates to study comple

232 veral biophysical techniques, can serve as a versatile screening and engineering platform.

233 perovskite chalcogenides are a new class of versatile semiconductors with high absorption coefficien

234 Our results establish BLISS as a versatile, sensitive and efficient method for genome-wid

235 the KZip(+) technology, we have developed a versatile set of LexAop-KZip(+) fly lines that can be us

236 ng RNAs, is an evolutionarily widespread and versatile silencing mechanism that plays an important ro

237 n made to solve parts of the above issues, a versatile solution is still absent.

238 tor for optical information processing, this versatile spin-cavity quantum transistor provides a soli

239 s of the group 14 elements are well-known as versatile starting materials in many chemical transforma

240 As inexpensive and versatile starting materials, such compounds continue to

241 the ease of coupling this process with other versatile, stereocontrolled reactions has enhanced the u

242 natural products or use of cyclopropanes as versatile strategic intermediates.

243 acellular bacterial pathogens have developed versatile strategies to generate niches inside the eukar

244 The versatile strategy based on molecular engineering greatl

245 ponsive proteins into hydrogels represents a versatile strategy for designing dynamically tunable mat

246 This facile synthetic process provides a versatile strategy for designing particles to new struct

247 In this report, we introduce a versatile strategy to synthesize polymers with tailored

248 results extend the scope of the already very versatile Suzuki-Miyaura reaction toward the synthesis o

249 we explore a general synthetic strategy for versatile synthesis of various holey transition metal ox

250 Here, we present an efficient and versatile synthetic methodology from which four diastere

251 The development of renewable monomers, the versatile synthetic routes to convert these monomers to

252 However, a robust and versatile synthetic strategy for these materials remains

253 lness of furans as powerful nucleophiles and versatile synthons.

254 ur study provides a sensitive, specific, and versatile system for fundamental research into the indiv

255 toxide react to form a highly attractive and versatile system that shows (reversible) silylation of a

256 veals that POM:gamma-CD constitutes a highly versatile system which gives aggregates with 1:1, 1:2, a

257 ults in the development of new, diverse, and versatile systems with prospects in bandgap engineering,

258 Despite these versatile tasks in mammalian biology, their skills on a

259 imensional solid and establishes M-EELS as a versatile technique sensitive to valence band excitation

260 enabled researchers to repurpose them into a versatile technology that is broadly revolutionizing bio

261 ropose a new approach to use Parylene C as a versatile template for patterning soft materials potenti

262 e proteins indicate that they should provide versatile templates for developing inhibitors of protein

263 high levels of stereoselectivity, affording versatile tertiary propargylic alcohols containing two s

264 The system is more versatile than current electrodialytic carbonate eluent

265 s, the proposed multi-scale approach is more versatile than the existing approaches for evaluating pe

266 In the drug delivery area, versatile therapeutic systems intended to yield customiz

267 e3 provide a platform for the realization of versatile time-reversal symmetry-breaking physics.

268 We present a versatile, time- and labor-efficient method to functiona

269 This strategy is versatile to a variety of MNPs and MOF crystals.

270 ystem CRISPR-Cas9 has been appropriated as a versatile tool for editing genomes, controlling gene exp

271 MegaSTAR is a versatile tool for generating sandwich ELISA-grade and b

272 the first time to our knowledge, could be a versatile tool for investigating the pathophysiological

273 ic gene expression, we view this method as a versatile tool for matching function to genetic classifi

274 spectroscopy, which has been proven to be a versatile tool for obtaining one dimensional absorption

275 The ICA represents a fast and versatile tool for single-cell sorting of peripheral pla

276 Our findings thereby enable a versatile tool for ultrafast and efficient control of li

277 fully open design of FlyPi make it a highly versatile tool in a range of applications, including the

278 RT is thus a versatile tool that can be used for both confocal micros

279 ectroscopy (2D IR) has been established as a versatile tool that can uniquely probe proteins structur

280 m may provide CPR and DPANN organisms with a versatile tool that could be used for adaptation to a dy

281 A versatile tool to enhance our understanding of the molec

282 e of hybridisation, they are set to become a versatile tool to fabricate sensitive and selective nove

283 pheres and negative for saddles-has proven a versatile tool to guide the self-assembly of defects suc

284 The CRISPR-Cas9 system provides a versatile toolkit for genome engineering that can introd

285 vitro models that should prove powerful and versatile tools for disease modelling and therapeutic ex

286 DNA transposons and retroviruses are versatile tools in functional genomics and gene therapy.

287 Antisense oligonucleotides (ASOs) are versatile tools that can regulate multiple steps of RNA

288 ire, utilize, and control this biochemically versatile trace element.

289 olutionary prerequisite for the functionally versatile tribosphenic molar morphology, which underlies

290 ts can be directly controlled, thus allowing versatile tuning of geometrical frustration and manipula

291 A versatile two-photon laser lithography is employed for L

292 iquitination events form a sophisticated and versatile ubiquitin code.

293 via a single-collision event and opens up a versatile, unconventional path to access this previously

294 ted alkenes is achieved for the synthesis of versatile unsymmetrical 1,2-diamine derivatives.

295 This provides a good example of versatile use of a protein structure in biological organ

296 y functionalized cyclopenta[b]indolines with versatile vinyl and nitro-groups.

297 ata and identify robust gene-sets along with versatile viral responsive genes.

298 A highly versatile water-soluble pyridine-spiropyran photoswitch

299 The technique is extremely versatile, with the local delivery of molecules highly t

300 The presented methodology is scalable and versatile without the need for elaborate phosphine ligan