ライフサイエンスコーパス: vertebral

1 -energy trauma) fractures, of which 62% were vertebral, 1% hip and 36% other nonvertebral fractures.

2 Spinal curvatures with no underlying vertebral abnormality (idiopathic scoliosis (IS)) most c

3 Nonetheless, very little is known about vertebral anatomy in the earliest stem tetrapods, becaus

4 he cerebral circulation with emphasis on the vertebral and basilar arteries (the posterior cerebral c

5 It involves mostly vertebral and basilar arteries.

6 en with severe osteoporosis, the risk of new vertebral and clinical fractures is significantly lower

7 ures, clinical fractures (a composite of non-vertebral and symptomatic vertebral), and non-vertebral

8 ore atherosclerotic stenosis or occlusion in vertebral and/or basilar arteries underwent large-vessel

9 a composite of non-vertebral and symptomatic vertebral), and non-vertebral fractures.

10 herapy [RRT]) and bone events (incident hip, vertebral, and all fractures).

11 Pelvis/hip, vertebral, and lower leg fractures were the most prevale

12 We sought the genetic cause of cardiac, vertebral, and renal defects, among others, in unrelated

13 We identified hip, vertebral, and upper arm fractures using ICD-9-CM codes.

14 ernal-zygotic ptk7 mutants (MZptk7) leads to vertebral anomalies associated with CS.

15 Vertebral anomalies in caudal regression syndrome may ar

16 rt stature, growth-plate irregularities, and vertebral anomalies, such as scoliosis.

17 enesis and the pathogenesis of lumbar/sacral vertebral anomalies.

18 n of MMC involves failure in neural tube and vertebral arch closure at early gestational ages, follow

19 Vertebral arch elements were present in early stem verte

20 nts: the vertebral body (or centrum) and the vertebral arches.

21 pods and raises questions about the presumed vertebral architecture of tetrapodomorph fish and later,

22 Here we describe the three-dimensional vertebral architecture of the Late Devonian stem tetrapo

23 sonography at the internal carotid (ICA) and vertebral arteries (VA).

24 ae leads to a complete loss of the bilateral vertebral arteries (VTAs) that extend along the ventrola

25 Imaging data on the patency of the vertebral arteries and posterior communicating arteries,

26 Eight studies that examined 5704 carotid or vertebral arteries in 1426 trauma patients met inclusion

27 ranial carotid arteries in 251 patients, and vertebral arteries in 82 patients.

28 ressure assessed at the internal carotid and vertebral arteries.

29 e catheterization of the internal carotid or vertebral arteries.

30 red at the internal carotid artery (ICA) and vertebral artery (VA) and CBF velocity at the middle cer

31 on the left side and dissection of the right vertebral artery and no ischemic changes within the brai

32 ence of congenital cerebrovascular variants; vertebral artery hypoplasia, and an incomplete posterior

33 No patients with isolated vertebral artery injuries had positive transcranial Dopp

34 injuries, but monitoring was not useful for vertebral artery injuries.

35 elayed stroke among patients who sustained a vertebral artery injury with or without additional vesse

36 ulted from carotid injury and 4 (26.7%) from vertebral artery occlusion (P = .03).

37 e studies of the exceedingly rare rotational vertebral artery syndrome have been added to the literat

38 including vertigo associated with rotational vertebral artery syndrome, as well as whiplash and degen

39 than the 'less-reactive' CA measured at the vertebral artery that was associated with WMH severity.

40 ion (CeAD), a mural hematoma in a carotid or vertebral artery, is a major cause of ischemic stroke in

41 ts), and most (97%) had L1 or mean T12 to L5 vertebral attenuation of 145 HU or less.

42 sis of extensive research: the ratio between vertebral base area and its height (A/H), and the ratio

43 o independent readers visually evaluated all vertebral bodies (n = 163) for the presence of abnormal

44 Chordomas are tumors that arise at vertebral bodies and the base of the skull.

45 Five porcine vertebral bodies in one pig underwent intervention (IRE

46 measure bone density of thoracic and lumbar vertebral bodies on computed tomographic (CT) images.

47 tebral bodies, heterogeneous signal from the vertebral bodies on T2 TIRM images, well-defined paraspi

48 es, hyperintense/homogeneous signal from the vertebral bodies on T2 TIRM images.

49 toff value of -80 to differentiate edematous vertebral bodies resulted in a sensitivity of 96.3%, spe

50 Failure load of the vertebral bodies was determined from destructive biomech

51 ion, and morphology of the tibiae and lumbar vertebral bodies were assessed by micro-computed tomogra

52 Twelve thoracic vertebral bodies were removed from three human cadavers

53 VNCa images were significantly different in vertebral bodies with and without edema (P < .001).

54 In all cases a destruction of vertebral bodies with end plates loss restriction and co

55 98.2%, and accuracy of 97.6% in the group of vertebral bodies with less than 50% sclerosis and/or air

56 epidural empyemas, abscess between adjacent vertebral bodies, abscesses beneath anterior longitudina

57 able to depict bone marrow in the collapsed vertebral bodies, especially in those with less than 50%

58 focal/heterogeneous contrast enhancement of vertebral bodies, heterogeneous signal from the vertebra

59 f vertebral bodies, low-grade destruction of vertebral bodies, hyperintense/homogeneous signal from t

60 diffuse/homogeneous contrast enhancement of vertebral bodies, low-grade destruction of vertebral bod

61 te cancer cells were either coimplanted with vertebral bodies, or inoculated in the tibiae of immunoc

62 cic spine, involvement of 2 or more adjacent vertebral bodies, severe destruction of the vertebral bo

63 ed to well-segmented areas of the developing vertebral bodies.

64 n infusion of donor BM cells isolated from 9 vertebral bodies.

65 f 98.3% for the differentiation of edematous vertebral bodies.

66 attenuation of the trabecular bone of the L5 vertebral body (L5HU) was measured.

67 , each consisting of two key components: the vertebral body (or centrum) and the vertebral arches.

68 more bilateral symmetric involvement of the vertebral body (P<.01), and continuation of vertebral bo

69 acture (P<.01), bone marrow contusion of the vertebral body (P=.01), muscle strain (P<.01) or tear (P

70 f occult vertebral body and facet fractures, vertebral body and facet contusions, intervertebral disk

71 dent readers assessed the presence of occult vertebral body and facet fractures, vertebral body and f

72 f the abdominal aorta at the level of the L3 vertebral body and its associations with multiple variat

73 ed diffuse bony involvement including the T7 vertebral body and left pedicle, ribs, pelvis, and calva

74 on chest radiograph with destruction of the vertebral body and preservation of the disc space.

75 In lumbar vertebrae reduced vertebral body area and wall thickness were accompanied

76 vertebral body (P<.01), and continuation of vertebral body changes with posterior pharyngeal wall ul

77 rvening joint change (P<.001), more cases of vertebral body collapse (P<.01), more bilateral symmetri

78 At least one moderate or severe vertebral body compression fracture was identified retro

79 DXA, 39 (48%) of 81 patients with unreported vertebral body compression fractures had a nonosteoporot

80 Most clinically important vertebral body compression fractures in nontrauma patien

81 iewed for the presence of moderate or severe vertebral body compression fractures of the lower thorac

82 OO was in the vertebral body for 18 of 57 patients, the neural arch fo

83 There were 141 thoracic and lumbar vertebral body fractures in the case set.

84 er system detects and anatomically localizes vertebral body fractures in the thoracic and lumbar spin

85 ith positive findings for fractures (59 with vertebral body fractures) and 10 control examinations (w

86 safe for the treatment of painful posterior vertebral body metastatic tumors.

87 e IRE electrode to the posterior wall of the vertebral body or the exiting nerve root were 2.93 mm +/

88 cant changes in the images of bone marrow in vertebral body scans; with a decrease in the intensity o

89 rument could be navigated into the posterior vertebral body tumors with a transpedicular approach.

90 47 tumors) with painful metastatic posterior vertebral body tumors, some of which were radiation ther

91 Lesions located in the vertebral body were excluded.

92 marrow, and skeletal muscle adjacent to the vertebral body were present.

93 ose single-section quantitative CT of the L4 vertebral body with use of a calibration phantom.

94 vertebral bodies, severe destruction of the vertebral body, focal/heterogeneous contrast enhancement

95 Bone needle was inserted into the vertebral body, followed by injection of PMMA cement.

96 NAT was measured at the level of the C5 vertebral body, subdivided into posterior (NATpost), sub

97 wer chondrogenic cells within the developing vertebral body, which fail to condense appropriately alo

98 N, or occurrence of first fracture (eg, hip, vertebral body, wrist).

99 ance in 1984 due to a hemangioma of cervical vertebral body.

100 d the destruction of the anterior rim of the vertebral body.

101 rienced relapse, with painful collapse of L3 vertebral body.

102 false-positive rate, as well as to calculate vertebral bone density, on CT images.

103 61.4 years +/- 11.8) performed for suspected vertebral bone metastases were included in this retrospe

104 e connected, and the developmental origin of vertebral bone-mineralizing cells.

105 ad normal hematopoiesis but reduced limb and vertebral bone.

106 n and spinal cord alignment to occipital and vertebral bones is crucial for coherent neural and skele

107 meningeal hemorrhages or deformities of the vertebral canal.

108 eletal disorder characterized by progressive vertebral, carpal and tarsal fusions, and mild short sta

109 n the medial sclerotome and later around the vertebral cartilage anlagen of body and pedicles.

110 osteoblast-independent mechanism for teleost vertebral centra formation.

111 This problem is especially complex given the vertebral chain of sympathetic ganglia derive secondaril

112 morphic) life cycle had an increased rate of vertebral column and body form diversification compared

113 of the segmented embryonic precursors of the vertebral column and musculature.

114 rdate body plan and for the formation of the vertebral column and numerous organs.

115 rmal development of the caudal aspect of the vertebral column and the spinal cord., It results in neu

116 known complete hominin cervical and thoracic vertebral column before 60,000 years ago.

117 The segmented vertebral column comprises a repeat series of vertebrae,

118 tor controlling rhythmic segmentation of the vertebral column during embryonic development.

119 entally revises our current understanding of vertebral column evolution in the earliest tetrapods and

120 t xenarthran mammals, which strengthened the vertebral column for locomotion.

121 The construction of the vertebral column has been used as a key anatomical chara

122 The vertebral column in the sacral area has large anterior a

123 bone fractures, spinal cord compression, and vertebral column instability.

124 Formation of the vertebral column is a critical developmental stage in ma

125 The mammalian vertebral column is highly variable, reflecting adaptati

126 he close proximity of the spinal cord to the vertebral column limits many conventional therapeutic op

127 e embryonic notochord and consequently adult vertebral column malformations.

128 which gives rise to the skeletal muscles and vertebral column of the body.

129 ntiated from the teratoma by the presence of vertebral column often with an appropriate arrangement o

130 ation, including re-patterning of the caudal vertebral column that is otherwise only seen in salamand

131 d signals are essential for formation of the vertebral column the phenotypes suggested that the lacZ

132 ed exclusively in mild defects in the caudal vertebral column.

133 , controls segmentation of precursors of the vertebral column.

134 discs (IVD) are essential components of the vertebral column.

135 Although several complete lumbar vertebral columns are known for early hominins, to date,

136 Two partial vertebral columns of Australopithecus sediba grant insig

137 Particular controversy surrounds whether vertebral component structures are homologous across ver

138 Vertebral compression fracture (VCF) is increasingly rec

139 %) patients with an unreported fracture, the vertebral compression fracture was not known clinically.

140 etect, anatomically localize, and categorize vertebral compression fractures at high sensitivity and

141 iction of bone marrow edema in thoracolumbar vertebral compression fractures in patients with osteopo

142 ve the detection rate of acute thoracolumbar vertebral compression fractures in patients with osteopo

143 T numbers between edematous and nonedematous vertebral compression fractures were found for both read

144 ive patients with 112 thoracic and/or lumbar vertebral compression fractures were studied between Jan

145 trate that human XylT2 deficiency results in vertebral compression fractures, sensorineural hearing l

146 ng depicted 46 edematous and 66 nonedematous vertebral compression fractures.

147 oplasty should be considered for symptomatic vertebral compression fractures.

148 traumatic bone marrow edema in patients with vertebral compression fractures.

149 for assessing traumatic bone marrow edema in vertebral compression fractures.

150 area and its height (A/H), and the ratio of vertebral coronal width to coronal height (W/H).

151 Vertnin genotype significantly affected vertebral counts as well.

152 uction of a Trp53-null allele attenuates the vertebral defects found in Pdgfra(PI3K/PI3K) neonates.

153 12Gso homozygotes present urinary and vertebral defects very similar to those associated with

154 n the mouse causes cerebellar hypoplasia and vertebral defects.

155 ebrates, much remains to be understood about vertebral development and evolution.

156 et Ctgf, indicates that Fat4-Dchs1 regulates vertebral development independently of Yap and Taz.

157 hin these genes will expand our knowledge on vertebral development using natural genetic variants seg

158 The importance of the Hox gene families in vertebral development was highlighted as significant ass

159 ered with some notochord-dependent aspect of vertebral development.

160 and structural features between carotid and vertebral dissection suggest that their pathophysiology

161 ne radiograms could be used as predictors of vertebral durability.

162 to the positional relationships between the vertebral elements, with the pleurocentra being unexpect

163 e total hip, and spine imaging shows several vertebral endplate deformities, but overall preservation

164 s, followed by partial volume averaging with vertebral endplates (173 [27.9%] of 620) and pedicle cor

165 y hominin spinal mobility, lumbar curvature, vertebral formula, and transitional vertebra position.

166 ociated with a significantly reduced risk of vertebral fracture among men with osteoporosis.

167 men with at least two moderate or one severe vertebral fracture and a bone mineral density T score of

168 and matched pair analyses were performed on vertebral fracture and patient levels.

169 points were the cumulative incidence of new vertebral fracture at 24 months and the cumulative incid

170 ts in this rare case of traumatic complex C2 vertebral fracture caused by a gunshot injury.

171 with bisphosphonates to reduce the risk for vertebral fracture in men who have clinically recognized

172 2.49) and with no history of hip or clinical vertebral fracture or of treatment for osteoporosis, fol

173 osteoporotic range and/or preexisting hip or vertebral fracture reduce fracture risk.

174 ams, making roentgenography a novel tool for vertebral fracture risk assessment in the future.

175 ne density as the most reliable parameter in vertebral fracture risk assessment.

176 eoporosis who were suspected of having acute vertebral fracture underwent DE CT and MR imaging.

177 nical fracture (nonvertebral and symptomatic vertebral fracture) at the time of the primary analysis

178 patients with at least 1 moderate-to-severe vertebral fracture, 62 (52.1%) had nonosteoporotic T-sco

179 Three- and 12-month vertebral fracture-free probability was 97.0% and 94.5%,

180 one patient with alendronate developed a new vertebral fracture.

181 the control patients sustained at least one vertebral fracture.

182 e recorded a significant reduction of 34% in vertebral fractures (0.66, 0.59-0.73), but only a small

183 0.59-0.73), but only a small effect for non-vertebral fractures (0.93, 0.87-0.99).

184 ctures (ranging from 0.90% to 1.86%) and non-vertebral fractures (ranging from 0.84% to 2.55%) remain

185 The yearly incidence of new vertebral fractures (ranging from 0.90% to 1.86%) and no

186 Children with ALL have a high incidence of vertebral fractures after 12 months of chemotherapy, and

187 New vertebral fractures after PVP were clustered within pati

188 rteen (52%) of the 25 children with incident vertebral fractures also had fractures at baseline.

189 lative risk reductions from 0.40 to 0.60 for vertebral fractures and 0.60 to 0.80 for nonvertebral fr

190 Incident hip and clinical vertebral fractures and initiation of treatment with bis

191 months of chemotherapy, and the presence of vertebral fractures and reductions in spine BMD Z-scores

192 utcomes included new vertebral, hip, and non-vertebral fractures as well as bone mineral density (BMD

193 Vertebral fractures at baseline increased the odds of an

194 Raloxifene may prevent vertebral fractures but may not improve BMD (low SOE).

195 with cystic fibrosis (CF), rib and thoracic vertebral fractures can have adverse effects on lung hea

196 bral hemangioma, in another 4 - pathological vertebral fractures due to metastases, and in one case -

197 The corresponding percentages of vertebral fractures for DXA and quantitative CT with a 5

198 nd reduced the incidence of new radiographic vertebral fractures in 1 high-quality trial.

199 Suspecting and promptly recognizing vertebral fractures in patients with AS could prevent se

200 or denosumab to reduce the risk for hip and vertebral fractures in women who have known osteoporosis

201 at the prevalence of osteoporosis is 25% and vertebral fractures is 10% in patients with AS.

202 lure, RRT, all fractures, hip fractures, and vertebral fractures occurred in 0.6%, 0.2%, 0.7%, 0.1%,

203 At 24 months, new vertebral fractures occurred in 28 (5.4%) of 680 patient

204 period of 24 months, a 48% lower risk of new vertebral fractures was observed in the romosozumab-to-a

205 Non-vertebral fractures were reported in 292 individuals, 15

206 two consecutive patients with 37 morphologic vertebral fractures were studied between October 2015 an

207 ctures) and 10 control examinations (without vertebral fractures), were performed.

208 e on the prevalence of osteoporosis, risk of vertebral fractures, and the recent advances in the trea

209 Denosumab also reduces risk for radiographic vertebral fractures, based on 1 trial.

210 comes included new and worsened radiographic vertebral fractures, clinical fractures (a composite of

211 % CI, 11% to 23%) had a total of 61 incident vertebral fractures, of which 32 (52%) were moderate or

212 in placebo-controlled trials to reduce only vertebral fractures.

213 al CT images assessed for moderate-to-severe vertebral fractures.

214 ertebral and symptomatic vertebral), and non-vertebral fractures.

215 The primary outcome was new radiographic vertebral fractures.

216 aratide reduces the risk of nonvertebral and vertebral fractures.

217 ab reduce the risk of hip, nonvertebral, and vertebral fractures; bisphosphonates are commonly used a

218 Non-vertebral fragility fractures occurred in 25 (4.0%) pati

219 is a skeletal malformation characterized by vertebral fusion.

220 ing embryogenesis was sufficient to generate vertebral fusions and scoliosis in the adult spine.

221 Moreover, the vertebral fusions in persons with MPS, coupled with evid

222 zed by pterygia, camptodactyly of the hands, vertebral fusions, and scoliosis.

223 hin the spine may lead to the development of vertebral fusions.

224 Proposed parameters describing vertebral geometry and/or shape can be established on th

225 by subsequent impairment in spinal cord and vertebral growth during fetal development.

226 ate deformities, but overall preservation of vertebral height.

227 cases the reason for vertebroplasty was the vertebral hemangioma, in another 4 - pathological verteb

228 Vertebral hemangiomas being the most common of all are s

229 Secondary outcomes included new vertebral, hip, and non-vertebral fractures as well as b

230 As is essential both for properly patterning vertebral identity at different axial levels and for mod

231 on a single CT section obtained at the L4-5 vertebral interface.

232 and who underwent CT that included the L4-5 vertebral interspace were included.

233 The lumbar vertebral level 4/5 IVDs harvested from 15-day-, 4- and

234 ional muscle area and bone density at the L3 vertebral level, compared with a group with no sarcopeni

235 ation values were significantly lower at all vertebral levels for patients with DXA-defined osteoporo

236 d subcutaneous adipose tissue (SAT) areas at vertebral levels T7 to L5.

237 umbar spinal stenosis at one or two adjacent vertebral levels to undergo either decompression surgery

238 ]) of trabecular bone between the T12 and L5 vertebral levels, with an emphasis on L1 measures (study

239 Similar performance was seen at all vertebral levels.

240 y of uridine monophosphate synthase, complex vertebral malformation, and brachyspina.

241 Congenital scoliosis is a common type of vertebral malformation.

242 Congenital vertebral malformations (CVM) occur in 1 in 1000 live bi

243 e focal notochord defects of the embryo with vertebral malformations (VM) in the adult.

244 teristic facial features, heart defects, and vertebral malformations.

245 The vertebral maturation pattern and extended brain growth m

246 Correlations between vertebral mechanical strength - its BMD, QCT density, A/

247 L3 and L4 vertebral mineral bone density, assessed by dual-energy

248 ertebrates is the specification of different vertebral morphologies, with an additional role in axis

249 ), mean age 54 +/- 12 years, was assessed by vertebral morphometry and data from patient records, sup

250 Routine measurements of BMD and vertebral morphometry are warranted in these patients fo

251 and trauma circumstances were collected from vertebral morphometry, patients' records, and questionna

252 e cycle complexity explain the variations in vertebral number and adult body form better than larval

253 ating, multiple genetic networks controlling vertebral number and identity, miR-196 is a critical pla

254 and 196b act redundantly to constrain total vertebral number.

255 allow eventual evolutionary changes of trunk vertebral numbers.

256 er interpretations of early hominin regional vertebral numbers.

257 ve not shown any benefit in the treatment of vertebral or basilar artery stenosis.

258 of a new symptomatic pathological fracture (vertebral or non-verterbal), or occurence of spinal cord

259 ts who received zoledronic acid had clinical vertebral or nonvertebral fractures, although this diffe

260 all patients with reported internal carotid, vertebral, or suspected intracranial artery aneurysms we

261 The mass had vertebral organization, limb and pelvic bones.

262 , including a possible posterior-to-anterior vertebral ossification sequence and the first evolutiona

263 fessionals who care for patients with native vertebral osteomyelitis (NVO).

264 omologous across vertebrates, how somite and vertebral patterning are connected, and the developmenta

265 ailed mechanisms that regulate and diversify vertebral patterning.

266 We show the potential for vertebral patterns to confer heightened sensitivity, wit

267 o 0.91 per patient-year and were highest for vertebral, pelvis/hip, and femur fractures.

268 he level in the control diet, on the NTD and vertebral phenotypes in Apobtm1Unc and Vangl2Lp mice, he

269 Vertebral precursors, called somites, provide one of the

270 ox genes, which are collinearly activated in vertebral precursors, repress Wnt activity with increasi

271 often occurred in the extracranial carotid, vertebral, renal, and coronary arteries.

272 These hits provide insight into human vertebral segmentation disorders and myopathies.

273 elitis episodes and extended a median of two vertebral segments (range, 1-12); in 21 of 48 (44%) ring

274 ubpial gadolinium enhancement extending >/=2 vertebral segments and persistent enhancement >2 months

275 Short transverse myelitis (STM; <3 vertebral segments) is considered noncharacteristic of n

276 ly extensive (greater than or equal to three vertebral segments) T2-hyperintensity in 44 of 50 (88%)

277 itudinally extensive spinal cord lesions (>3 vertebral segments), and absence of oligoclonal IgG band

278 inal cord T2-hyperintense lesion less than 3 vertebral segments, AQP4-IgG seropositivity, and a final

279 panied by a spinal cord lesion spanning >/=3 vertebral segments.

280 ary prevention, and the role of stenting for vertebral stenosis is being investigated.

281 quantitative computed tomography, estimated vertebral strength by finite element analysis, and self-

282 nd spine aBMD, vertebral vBMD, and estimated vertebral strength.

283 rameters that could be used as predictors of vertebral strength.

284 iomechanical tests were performed to measure vertebral strength.

285 -ganglionic neurons that comprise a chain of vertebral sympathetic ganglia, arises developmentally is

286 rsal fusion and extensive posterior cervical vertebral synostosis, cardiac septal defects with valve

287 lower aortic root strain (P=0.05) and higher vertebral tortuosity index (P=0.01) were independently a

288 notype severity such as aortic stiffness and vertebral tortuosity index have been proposed.

289 Vertebral tortuosity index was calculated as previously

290 onset of scoliosis without malformations of vertebral units.

291 Vertebral vBMD and strength improved with teriparatide t

292 se, as well as increased hip and spine aBMD, vertebral vBMD, and estimated vertebral strength.

293 cerebral venous drainage through the IJV or vertebral vein was found between patients with multiple

294 tions of the internal jugular vein (IJV) and vertebral vein.

295 rtebral veins, and reflux in the IJVs and/or vertebral veins in the sitting or supine position.

296 ways, and absence of flow in the IJVs and/or vertebral veins were found in 3 (6.8%), 2 (4.5%), and 3

297 of detectable blood flow in the IJVs and/or vertebral veins, and reflux in the IJVs and/or vertebral

298 Narrowing of vertebral vessels was the most common change (27 patient

299 ion included various degrees of narrowing of vertebral vessels, anterior, posterior and posterior com

300 ercent change in bone remodeling markers and vertebral volumetric BMD (vBMD) by quantitative computed