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3 to be involved in sex determination although very little is known about both its structure and functi
5 animal body sizes over the last century, but very little is known about changes in plant sizes, even
6 studies on facial expression interpretation; very little is known about children's ability to recogni
9 timulants, such as caffeine or nicotine, but very little is known about drugs that can enhance the co
10 documented (e.g., entanglement and choking), very little is known about effects on assemblages and co
11 by a unique combination of factors, however very little is known about factors that control the deve
12 el plant Arabidopsis (Arabidopsis thaliana), very little is known about floral induction in tulip.
14 ed by members of several chaperone families, very little is known about folding of proteins in the in
15 ntributing to deafness have been identified, very little is known about genes/variants modulating the
20 wn about the mechanism of DNA translocation, very little is known about how ATP modulates motor-DNA i
21 flow in angiogenesis and vessel remodeling, very little is known about how changes in vessel diamete
24 al for predicting carbon uptake and storage, very little is known about how eCO2 affects nutrient cyc
25 crucial role in branching morphogenesis, but very little is known about how endothelial cells contrib
30 ms are implicated in nicotine's actions, but very little is known about how nicotinic acetylcholine r
32 capacity of replication origins to initiate, very little is known about how or if cells actively regu
34 nt splicing is regulated by phosphorylation, very little is known about how protein kinases phosphory
35 factors that contribute to reward value, but very little is known about how reward is computed in the
36 essential effectors are poorly defined, and very little is known about how spacious vacuoles are for
38 modulated by their cultural background, but very little is known about how such a culture-specific p
41 umed processed tomato product worldwide, but very little is known about how the manufacturing process
43 is implicated in many chronic diseases, but very little is known about how the unfolded protein resp
46 known as lipoviral particles (LVP); however, very little is known about how these particles are creat
48 with combined nutritional deficiencies, yet very little is known about how these signalling pathways
49 e associations with dangerous taste stimuli, very little is known about how these stored emotional as
51 ous progress in understanding their origins, very little is known about how to control the conduction
52 ur understanding of sensory map development, very little is known about how topographic representatio
56 modified by different fatty acids; however, very little is known about how zDHHC enzymes contribute
58 hage activation were recently uncovered, but very little is known about interactions of CPPD crystals
59 ed with negative cardiometabolic end points, very little is known about interindividual variation in
61 ytial virus (RSV) acts at mucosal sites, and very little is known about its ability to influence airw
62 mainly using electrophysiological criteria, very little is known about its anatomical organization.
64 role in the development of neural networks, very little is known about its dynamics and the underlyi
65 cted action and reward-guided behaviors, yet very little is known about its involvement in taste codi
66 fying molecular characteristics of the scar, very little is known about its mechanical properties.
67 Despite the importance of this reaction, very little is known about its mechanism, and as a conse
69 es (ODNs) by chemical DNA synthesis and thus very little is known about its physicochemical propertie
70 se (MGL) is a recently identified lipase and very little is known about its regulation and function i
71 hallenges posed by the clonal nature of MAE, very little is known about its regulation; in particular
72 plays a role in many biologic processes, yet very little is known about its role in metabolism of dru
75 h much is known about total Zn(2+) in cells, very little is known about its subcellular distribution.
76 the region inhibits natural aggression, yet very little is known about its underlying neural activit
79 onsiderably increased over the past decades, very little is known about molecular events involved in
80 e of MreB for cell morphology and viability, very little is known about MreB-interacting factors.
83 osomes derived from hematopoietic cells, but very little is known about NK cell exosomes, despite the
84 eem to prefer monosaccharides as substrates, very little is known about OprB-mediated sugar uptake.
87 esolution of telomeric secondary structures, very little is known about RECQL4, the RecQ helicase mut
89 and mechanisms underlying individual steps, very little is known about regulatory mechanisms control
90 being discovered more than two decades ago, very little is known about requirements for NaPi-III tra
91 in a skin-associated lymphoid tissue (SALT), very little is known about skin B-cell responses as well
92 uantity of sequences in different databases, very little is known about specific virus isolates and t
95 However, despite its clinical prevalence, very little is known about the action of TMS at the cell
96 ntinually evolving HIV-1 pandemic.IMPORTANCE Very little is known about the ancestral HIV-1 strains t
99 importance of the polymer surfactant shell, very little is known about the atomistic structure of th
101 le in innate immunity in plants and animals, very little is known about the biological function of th
108 chromatin conformation studies are emerging, very little is known about the chromatin conformation of
109 oral role of BLA inputs to sensory cortices, very little is known about the circuit organization of B
110 ave addressed the function of NRG1 in brain, very little is known about the cleavage and shedding mec
111 be familial or occur in isolation; however, very little is known about the clinical characteristics,
113 considerable research effort over the years, very little is known about the complex in vivo events th
115 ugh many studies have linked AMPK with mTOR, very little is known about the connection between AMPK a
116 processing in the ferret (Mustela putorius), very little is known about the connections between the d
118 lysaccharide capsule and melanin production, very little is known about the contribution of Plb1 to c
119 ubstrates have been characterized in plants, very little is known about the corresponding ubiquitin a
121 r fields of the adult hippocampal formation, very little is known about the development of these path
122 Despite the prevalence of paused Pol II, very little is known about the dynamics of these early e
123 d and Drug Administration-approved drug, but very little is known about the effect of adenosine on IC
125 s been well characterized in proteobacteria, very little is known about the effectors of this signali
126 defense against encapsulated pathogens, but very little is known about the effects of Ab binding on
127 to microbial infections is well established, very little is known about the effects of health-promoti
129 on with thermal or enzymatic treatments, but very little is known about the effects of UV light.
130 biogenesis resulting in pore activation, but very little is known about the elongation steps that fol
131 development of small-molecule therapeutics, very little is known about the environmental factors ass
132 ll many questions that remain unanswered and very little is known about the etiology or genetic predi
133 n studied in animals, plants, and fungi, but very little is known about the evolution of sexes in oth
134 Although central for sexual differentiation, very little is known about the expression profile, cellu
138 ng aberrantly expressed miRNAs in leukaemia, very little is known about the functional consequences o
144 gh its biological importance is appreciated, very little is known about the genome dimerization proce
149 gration have been identified; however, still very little is known about the intracellular molecular m
153 nd macrophages has been extensively studied, very little is known about the mechanism by which the au
155 ence of strongly bound CEs in the CETP core, very little is known about the mechanism of CE/triglycer
158 structural features of these invaginations, very little is known about the mechanism underlying thei
160 n is known to be regulated at the RNA level, very little is known about the mechanisms involved.
161 various stimuli including hypoxia; however, very little is known about the mechanisms that confine i
162 y caspases in vitro and in vivo as well, but very little is known about the mechanisms that regulate
163 e likelihood of receiving rewards ourselves, very little is known about the mechanisms that underpin
165 e to methodological and technical challenges very little is known about the mediation of these intera
167 ns have been seen in MDS marrow progenitors, very little is known about the molecular alterations in
168 ghout life and to contribute to obesity, yet very little is known about the molecular circuits that c
172 ing hemichordate (Saccoglossus kowalevskii), very little is known about the molecular mechanism under
173 ite its important role in plant development, very little is known about the molecular mechanism with
174 ograming is at the heart of development, yet very little is known about the molecular mechanisms prom
176 e of AOC1 in regulating polyamine breakdown, very little is known about the molecular mechanisms that
183 standing microtubule organizing centers, yet very little is known about the molecular structure of it
184 ors such as leukotrienes and prostaglandins, very little is known about the molecules involved in lym
185 a fundamental process in adipocyte biology, very little is known about the morphological changes tha
186 owever, it is rare in adults, and therefore, very little is known about the most appropriate treatmen
187 terminants of this preferential sparing, but very little is known about the myogenic cells in this mu
188 to the cortex have been extensively studied, very little is known about the nature of the signals tha
192 ave been studied for more than a century but very little is known about the non-equilibrium processes
198 genesis of cutaneous acute GVHD (aGVHD), but very little is known about the pathogenesis of chronic G
204 esis and ABA levels in angiosperms; however, very little is known about the physiological trigger for
205 eir relevance in host/pathogen interactions, very little is known about the pore stoichiometry and as
206 re is mounting evidence for this hypothesis, very little is known about the precise filtering mechani
210 ynamics play a role in varicosity formation, very little is known about the proteins that directly im
211 n function, localization, and stability, yet very little is known about the ratios of these modificat
213 tanding of beta-cell regeneration in adults, very little is known about the regeneration of the non-b
214 inositol levels and neurological disorders, very little is known about the regulation of inositol sy
216 eins have been reported in human cancer, and very little is known about the regulation of their activ
217 n almost every aspect of RNA metabolism, yet very little is known about the regulation of this class
218 essor in a variety of cancer types; however, very little is known about the regulation of this protei
219 ental blood flow during human pregnancy, yet very little is known about the regulatory mechanisms.
221 rate to a limited extent following vagotomy, very little is known about the response of central vagal
222 studied in aggressive B-cell lymphomas, but very little is known about the risk in peripheral T-cell
223 )-mediated signaling in cancer pathogenesis, very little is known about the role GPCRs play in TNBC.
225 e of the most studied proteases in bacteria, very little is known about the role of ClpXP in mitochon
230 embryonic lethality of Pbmr1-null mice, but very little is known about the role of PBAF, or its sign
232 vely regulate cocaine-induced behaviors, but very little is known about the role of specific HATs in
235 tegrator subunit causes snRNA misprocessing, very little is known about the role of the individual su
238 terious in development and promotes disease, very little is known about the signaling pathways that r
240 omposed predominately of the protein Ribeye, very little is known about the structural dynamics of ri
241 ucturally characterize fibrils of Abeta1-40, very little is known about the structure of amyloid fibr
244 , seawater sulfate concentration is high and very little is known about the sulfur metabolism of mari
248 understanding virus' evolutionary dynamics, very little is known about the topography of virus adapt
249 the glycolysis pathway in effector T cells, very little is known about the transcriptional mechanism
251 rray of malignant tumor cell types; however, very little is known about the transcriptional regulatio
252 espite the potential of plant based methods, very little is known about the underlying biochemical re
254 r the survival of a virus or an organism but very little is known about the underlying mechanisms.
255 generation of chronic pain states; however, very little is known about the underlying molecular mech
258 ead in terrestrial and aquatic environments, very little is known about the urease activity and regul
260 al diseases are emerging in aquaculture, but very little is known about the viruses and the diseases
262 hlighted clues to the success of this group, very little is known about their adaptive response to ch
264 DMC patients has been extensively described, very little is known about their cerebral anomalies, whi
266 m through wastewater and animal farm runoff, very little is known about their effects in the environm
267 s) on neuronal function are well understood, very little is known about their effects on cells of the
268 spite the widespread use of these compounds, very little is known about their effects on mood states.
269 own to utilize protein ADP-ribosylation, yet very little is known about their enzymes that synthesize
270 have been well studied in woody plants, but very little is known about their function in more ancien
272 of these genes can be present, but, to date, very little is known about their functional activity.
273 ce of voltage-gated ion channels in neurons, very little is known about their functional properties i
276 iated microbial species in wound infections, very little is known about their interspecies relationsh
277 s of the Neotropical epiphyte diversity, yet very little is known about their origin and diversificat
278 d for these symbiotic receptor-like kinases, very little is known about their phosphorylation substra
280 ded antisense RNAs (asRNAs) in bacteria, but very little is known about their possible functions.
281 dulators of gene expression in bacteria, yet very little is known about their prevalence and function
282 nes have been characterized in chickens, but very little is known about their receptors and their fun
283 n pathogenesis of tuberculous pleuritis, but very little is known about their response to anti-tuberc
284 circulating inflammatory monocytes; however very little is known about their role in liver diseases.
285 soforms of Pcyt2, -alpha and -beta; however, very little is known about their specific roles in this
286 tronic states exist at these boundaries, but very little is known about their structural properties.
287 where Schlenk-type equilibria are involved, very little is known about their structure in solution.
290 numerous phosphorylation sites on TRPM7, but very little is known about TRPM6 phosphorylation or site
295 ain processes rewards we will get ourselves, very little is known about vicarious reward processing.
298 role of the 5'UTR in translation initiation, very little is known about whether m(6)A modification in
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