ライフサイエンスコーパス: vesicular transport

1 g stimulates synaptic delivery of PSD-95 via vesicular transport.

2 in and dynein function collectively to drive vesicular transport.

3 he apoplast) via transporters, channels, and vesicular transport.

4 the endoplasmic reticulum (ER) by retrograde vesicular transport.

5 the endoplasmic reticulum (ER) by retrograde vesicular transport.

6 onal cells that is thought to be involved in vesicular transport.

7 surface to the endoplasmic reticulum (ER) by vesicular transport.

8 n and Htt-associated protein-1 to facilitate vesicular transport.

9 of ARF-bound GDP with GTP to regulate Golgi vesicular transport.

10 metabolism of APP by altering its endocytic vesicular transport.

11 nal COPI-, COPII-, and microtubule-dependent vesicular transport.

12 ed by bacterial pathogens to manipulate host vesicular transport.

13 table signs of neurodegeneration or abnormal vesicular transport.

14 ng X-chromosome-linked genes associated with vesicular transport.

15 ectors that mediate all the known aspects of vesicular transport.

16 for peptide precursors as sorting signals in vesicular transport.

17 nsible for most retrograde microtubule-based vesicular transport.

18 lgi localization of rab1a, a key mediator of vesicular transport.

19 also facilitate late-endosome-to-trans-Golgi vesicular transport.

20 n membranes, enabling the protein to undergo vesicular transport.

21 the endoplasmic reticulum (ER) by retrograde vesicular transport.

22 cytoskeleton reorganization, and protein and vesicular transport.

23 tor generation, and cytokine release through vesicular transport.

24 ope and the release of IL-12 but not IL-4 by vesicular transport.

25 M130, a Golgi-associated protein involved in vesicular transport.

26 h a model whereby PLD2 plays a role in Golgi vesicular transport.

27 d by homology to yeast Sec34p, implicated in vesicular transport.

28 regulates a cis-Golgi step in intracellular vesicular transport.

29 -containing protein implicated in regulating vesicular transport.

30 nctions of Rab25 and Rab11a in postendocytic vesicular transport.

31 legans research has provided to the field of vesicular transport.

32 mbrane t-SNARE proteins are also involved in vesicular transport.

33 ment to human bronchial epithelial cells and vesicular transport.

34 pathway, and 3) degradation does not require vesicular transport.

35 hocyte-like cells by a process that requires vesicular transport.

36 es, Arfs and Ypt/rabs, are key regulators of vesicular transport.

37 family play a key role in the regulation of vesicular transport.

38 e Golgi apparatus and may have a function in vesicular transport.

39 Rab family are involved in the regulation of vesicular transport.

40 iated with partial restoration of Z alpha1AT vesicular transport.

41 the endoplasmic reticulum (ER) by retrograde vesicular transport.

42 itial rate that exceeds that of conventional vesicular transport.

43 rab family are involved in the regulation of vesicular transport.

44 lular compartments and are key regulators of vesicular transport.

45 a biochemical pathway that is essential for vesicular transport.

46 e remained dispersed, suggesting a defect in vesicular transport.

47 broader context of clathrin-dependent plant vesicular transport.

48 es with G-proteins to regulate intracellular vesicular transport.

49 mmobile complexes on microtubules that limit vesicular transport.

50 e and helps to promote the directionality of vesicular transport.

51 erentiation/survival, T-cell activation, and vesicular transport.

52 tions to uncovering the mechanisms governing vesicular transport.

53 sed as an intervention after reinitiation of vesicular transport.

54 o rhabdomere membranes via a Rab11-dependent vesicular transport.

55 med are carried through the Golgi network by vesicular transport.

56 livered to the lumen of the Golgi complex by vesicular transport.

57 transition (EMT), epigenetic regulation and vesicular transport.

58 rocesses, including endocytosis, repair, and vesicular transport.

59 Previous work has identified distinct vesicular transport activities for the different classic

60 al phenotypes consistent with a reduction in vesicular transport activity and neurosecretion.

61 reticulum remains functionally connected by vesicular transport after its fragmentation in cells exp

62 Microtubule depolymerization disrupted vesicular transport along microtubules and caused the ac

63 Antibodies to Htt inhibited vesicular transport along microtubules, suggesting that

64 nnate immunity, cytoskeletal remodeling, and vesicular transport also exhibited differential expressi

65 , cardinal Nef functions affecting host cell vesicular transport and actin dynamics were fully preser

66 ransferase activity, have a critical role in vesicular transport and activate a phospholipase D (PLD)

67 rganization and retromer- and ESCRT-mediated vesicular transport and degradation of essential raft pr

68 For applications such as the study of vesicular transport and drug delivery, there is a pressi

69 y, GMIP-down-regulated cells showed impaired vesicular transport and exocytosis, while inhibition of

70 with the Rab27a effector JFC1 and modulates vesicular transport and exocytosis.

71 genes encoding proteins associated with ATP vesicular transport and fusion, including vesicle-associ

72 ) translocation, ER-to-Golgi trafficking and vesicular transport and fusion.

73 cal functions including signal transduction, vesicular transport and maintenance of cellular architec

74 single particles and they cluster during the vesicular transport and maturation.

75 s likely to function in clathrin-independent vesicular transport and membrane fusion events necessary

76 s play central roles in synaptic plasticity, vesicular transport and mitochondrial function.

77 smic dynein and its activator dynactin drive vesicular transport and mitotic spindle organization.

78 rfamily and are recognized as key players in vesicular transport and organelle dynamics in eukaryotic

79 ized as critical components in intracellular vesicular transport and phospholipase D activation.

80 ized as critical components in intracellular vesicular transport and phospholipase D activation.

81 terol itself as well as proteins involved in vesicular transport and protein glycosylation and degrad

82 cell type-restricted role for LIS1 in large vesicular transport and provide the first quantitative s

83 lly neuronal differentiation, axonal growth, vesicular transport and release, and ionic conductance.

84 ablishes a newly identified role for Bves in vesicular transport and reveals a novel, broadly applied

85 with VAMP3, a SNARE protein that facilitates vesicular transport and specifically recycles transferri

86 ontextual fear-conditioning and identify the vesicular transport and synaptogenesis pathways as the m

87 idence for an alternative novel mechanism of vesicular transport and vacuolar sequestration of anthoc

88 gulation, ubiquitination, dephosphorylation, vesicular transport, and cell adhesion.

89 lecule transport, cell wall maintenance, and vesicular transport, and include many open reading frame

90 -modifying enzymes, molecular motor-mediated vesicular transport, and intracellular signaling by loca

91 angers and cytoskeletal elements involved in vesicular transport, and raises the possibility that abn

92 es, proteins of the translational machinery, vesicular transport, and signaling.

93 es: one transcellular, via caveolae-mediated vesicular transport, and the other paracellular, through

94 functions, and the other with transcription, vesicular transport, and ubiquitination.

95 S-acylation/deacylation cycles and vesicular transport are critical for an adequate subcell

96 AB23, encoding a small GTPase that regulates vesicular transport, are present in the majority of case

97 Syntaxins are thought to function during vesicular transport as receptors on the target membrane

98 ts, those interfering with the intracellular vesicular transport as well as inhibition of the fusion

99 ch functions in endosome-to-Golgi retrograde vesicular transport, as a critical player in sphingolipi

100 G (AnkG), a cytoskeletal protein involved in vesicular transport, as a novel aldosterone-induced prot

101 emodeling is important for the regulation of vesicular transport associated with exocytosis, but a di

102 The small GTPase Sec4p is required for vesicular transport at the post-Golgi stage of yeast sec

103 a mediator of endoplasmic reticulum to Golgi vesicular transport, at T75 to be regulated by TAK1 in v

104 Vesicular transport between secretory compartments requi

105 c leaflet is essential for +ALPS binding and vesicular transport between the EE and the TGN.

106 ype II membrane protein that is required for vesicular transport between the endoplasmic reticulum an

107 -kD hydrophilic protein that is required for vesicular transport between the ER and Golgi complex.

108 4 kD), a new mammalian v-SNARE implicated in vesicular transport between the ER and the Golgi.

109 eins to the TGN requires continual cycles of vesicular transport between the TGN and endosomal compar

110 ily of clathrin adaptor proteins involved in vesicular transport between the trans-Golgi network and

111 ntracellular site and that agents that block vesicular transport block responses of neutrophils to li

112 feldin A-induced endoplasmic reticulum/Golgi vesicular transport block.

113 everal proteins that have been implicated in vesicular transport but do not belong to any of the t-SN

114 nesin motor proteins are used for long-range vesicular transport but microtubules do not extend into

115 ng agents colchicine or nocodazole abrogated vesicular transport but not the flow of the nanotube sur

116 Rab GTPases play an essential role in vesicular transport by coordinating the movement of vari

117 Rab proteins and their effectors facilitate vesicular transport by tethering donor vesicles to their

118 Rab GTPases and their effectors facilitate vesicular transport by tethering donor vesicles to their

119 cant structural and mechanistic parallels to vesicular transport by the clathrin/AP2 system.

120 This vesicular transport can be reconstituted by using three

121 ation, protein folding, quality control, and vesicular transport can be well predicted by the single

122 complexity by which a single small GTPase in vesicular transport can coordinate its multiple steps to

123 ed that LTP-mediated lipid trafficking, like vesicular transport, can be subject to tight Ca(2+)regul

124 GN) is the sorting of proteins into distinct vesicular transport carriers that mediate secretion and

125 embrane asymmetry and play critical roles in vesicular transport, cell polarity, signal transduction,

126 associated with multiple functions including vesicular transport, cell signaling, oxidation state, cy

127 , general bud site selection, cell polarity, vesicular transport, cell wall synthesis, protein modifi

128 veolae and is implicated in the processes of vesicular transport, cholesterol balance, transformation

129 ells, these vesicles coalesce to form tubulo-vesicular transport complexes (TCs), which shuttle anter

130 bladders, which was blocked by inhibitors of vesicular transport, connexin hemichannels, ABC protein

131 observe both direct delivery of tubular and vesicular transport containers (TCs) from sorting endoso

132 These pathways commonly depend on vesicular transport controlled by Rabs, small GTPases in

133 amphetamine treatment and suggested that non-vesicular transport could be the main mechanism establis

134 e leads to cellular abnormalities, including vesicular transport defects and increased endoplasmic re

135 Other over-responders are annotated to have vesicular transport defects, traceable to lipid defects

136 ole in sustaining a microtubule track during vesicular transport deserves investigation.

137 Vesicular transport enables the export of large molecule

138 A twofold increase in vesicular transport enhances the vesicular capacity for

139 Precise regulation of these two aspects of vesicular transport ensures efficient cargo transfer whi

140 Vesicular transport events appear to be facilitated by t

141 We now describe serum-regulated upstream vesicular transport events leading to centrosomal Rab8 a

142 ized as critical components in intracellular vesicular transport, exist in an inactive cytosolic form

143 in inflammation/immunity, uptake/transport, vesicular transport/exocytosis, apoptosis/cellular stres

144 atter homologue, p20, has a putative role in vesicular transport from ER to Golgi complex.

145 Thus, TBC1D14- and Rab11-dependent vesicular transport from REs contributes to and regulate

146 have used brefeldin A (BFA), which inhibits vesicular transport from the ER to the Golgi, to demonst

147 rapidly, in a process that does not require vesicular transport from the ER.

148 Deletion of PEP12, a gene required for vesicular transport from the Golgi to the prevacuolar co

149 tates the efficient initiation of retrograde vesicular transport from the neurite tip.

150 nomeric clathrin-adaptor protein involved in vesicular transport from the TGN.

151 major player in clathrin coat formation for vesicular transport from the trans-Golgi to the endocyti

152 e important functions beyond their classical vesicular transport functions, including nutrient sensin

153 SNAP, other proteins apparently unrelated to vesicular transport (glyceraldehyde-3-phosphate dehydrog

154 tor (ARF) 6 has been shown to play a role in vesicular transport; however, the expression and subcell

155 Rab GTPases, key regulators of vesicular transport, hydrolyze GTP very slowly unless as

156 osolic protein thought to play a key role in vesicular transport in all eukaryotic cells.

157 m used by Legionella pneumophila to modulate vesicular transport in both protozoan and mammalian host

158 animals that are characterized by defects in vesicular transport in cell bodies of motor neurons, axo

159 ar membrane fusion, an essential process for vesicular transport in cells.

160 ar membrane fusion, an essential process for vesicular transport in cells.

161 d to explain both constitutive and regulated vesicular transport in eukaryotic cells, including relea

162 on, cargo protein sorting, and regulation of vesicular transport in eukaryotic cells.

163 The discovery of vesicular transport in fungi opens many new avenues for

164 volution of the Rab family in particular and vesicular transport in general, and may be used to predi

165 ization; GSLs are required for intracellular vesicular transport in resorption-active intestine.

166 of LPS and ceramide and point to a role for vesicular transport in responses to these mediators.

167 of pre-Golgi intermediates and required for vesicular transport in the early secretory pathway.

168 itted a careful evaluation of the role(s) of vesicular transport in transmitter-specific behaviors.

169 SEC24 is essential for vesicular transport in vivo because depletion of Sec24p

170 member of a gene family believed to regulate vesicular transport in yeast, but without known function

171 function, specifically in the regulation of vesicular transport, in specific regions of the develope

172 ormation rather than the situation with most vesicular transport, in which the forming vesicle concen

173 l cAMP (DBcAMP), stimulators of transcytotic vesicular transport, increased the biliary recovery of D

174 The vesicular transport inhibitor brefeldin A inhibited CCE

175 AP complexes play roles in the formation of vesicular transport intermediates and the selection of c

176 ent studies have demonstrated that polarized vesicular transport involving Rab8 and its guanine nucle

177 Vesicular transport is a general mechanism that governs

178 This dataset yields insights into how vesicular transport is adapted to the specialized functi

179 Non-vesicular transport is mediated by the interaction of me

180 ar pathway and suggest that ER to peroxisome vesicular transport is not required to provide lipids fo

181 The mechanism of vesicular transport is not well understood, and little i

182 The role of the class VI myosins in vesicular transport is particularly intriguing because t

183 Thus, although vesicular transport is the limiting factor determining q

184 Microtubule-based vesicular transport is well documented in epithelial cel

185 GTPases, the key organizers of intracellular vesicular transport, is essential for their function.

186 s a distinct myosin function, presumably the vesicular transport, is involved in elongation of the ro

187 d with calcein AM under conditions that slow vesicular transport (low temperature and stationary grow

188 These include the induction of the RAB vesicular transport machinery and a general down-regulat

189 ce locus, rhg1, identified expression of the vesicular transport machinery component, alpha soluble N

190 The experiments indicate a role for the vesicular transport machinery during infection of soybea

191 bits the expression of key components of the vesicular transport machinery, and down-regulates Glutam

192 express components of the insulin-sensitive vesicular transport machinery, namely, VAMP2, syntaxin-4

193 assays, we identified the components of the vesicular transport machinery, the GEF Rabin8 and the GT

194 toreceptors as part of the cell signaling or vesicular transport machinery.

195 of a defense response by the activity of the vesicular transport machinery.

196 A vesicular transport mechanism was confirmed by colocaliz

197 ole/lysosome by a constitutive non-classical vesicular transport mechanism, the cytoplasm to vacuole

198 vels in nerve terminals are 5-7 mm, and that vesicular transport mechanisms are not saturated under b

199 IL-16 also elicited brefeldin A-inhibitable, vesicular transport-mediated release of preformed IL-4,

200 eukin (IL)-16, eotaxin, and RANTES stimulate vesicular transport-mediated release of preformed, granu

201 IL-16 induced the rapid vesicular transport-mediated release of RANTES.

202 of fundamental cellular processes, including vesicular transport, mitosis, and cell migration.

203 A core prediction of the vesicular transport model is that COPI vesicles are resp

204 perspective on the facilitated diffusion and vesicular transport models to account for the emerging c

205 Membrane budding is a key step in vesicular transport, multivesicular body biogenesis, and

206 sly to identify several proteins involved in vesicular transport (N-ethylmaleimide-sensitive fusion p

207 utophagy and lysosomal catabolism reflecting vesicular transport obstruction and defective lysosomal

208 1 transport activity was normal, as shown by vesicular transport of [(3)H]17beta-estradiol-17-beta-(D

209 lar degradation of Abeta and facilitated the vesicular transport of Abeta to lysosomes.

210 phoid follicle-associated epithelium conduct vesicular transport of antigens from the mucosal surface

211 g demonstrated that PKC inhibitors inhibited vesicular transport of apoE to the plasma membrane.

212 osomal disturbance) or alter the polarity of vesicular transport of autophagosomes on microtubules, c

213 Here we show that AbetaOs reduce vesicular transport of brain-derived neurotrophic factor

214 ved particular attention for its role in the vesicular transport of cationic transmitters as well as

215 the sphingolipid sphingomyelin requires non-vesicular transport of ceramide from the endoplasmic ret

216 uggests that ATP11B contributes to secretory vesicular transport of cisplatin from Golgi to plasma me

217 on of the microtubule cytoskeleton disturbed vesicular transport of DHE but not its enrichment in the

218 lvement of vesicular glutamate transports in vesicular transport of glutamate.

219 ansgenic expression of Rab4, which regulates vesicular transport of heptahelical receptors to plasma

220 between HRas and PI3K, locally reinforced by vesicular transport of HRas to the axonal growth cone.

221 model of retrograde signaling whereby rapid vesicular transport of ligand-receptor complex from the

222 icient in responses to LPS exhibit defective vesicular transport of LPS and ceramide and point to a r

223 their membrane composition by regulating the vesicular transport of membrane-bound sterol regulatory

224 Indeed, the vesicular transport of most classical transmitters invol

225 ytosis, but the proteins responsible for the vesicular transport of neurotransmitters are still being

226 rable evidence supports a model in which the vesicular transport of neurotrophin-Trk complexes transm

227 sphate (Man-6-P) receptors (MPRs) direct the vesicular transport of newly synthesized lysosomal enzym

228 xits of interendothelial spaces; and (v) the vesicular transport of orosomucoid is strongly inhibited

229 In contrast to vesicular transport of other cargo via glycolipids, Py p

230 osome (MVB) plays a key role in coordinating vesicular transport of proteins between the Golgi comple

231 in complexes (COPI and COPII), which mediate vesicular transport of proteins to and from the ER.

232 Whereas vesicular transport of Tf and efflux of DHE from the ERC

233 PKD1 influences cell migration by directing vesicular transport of the alphavbeta3 integrin heterodi

234 Although vesicular transport of the H-Ras protein from the Golgi

235 However, vesicular transport of the principal excitatory transmit

236 ic vesicles, but the protein responsible for vesicular transport of the principal excitatory transmit

237 Silencing HTT reduces vesicular transport of TrkB in striatal neurons.

238 of Arf-bound GDP with GTP for initiation of vesicular transport or activation of specific enzymes th

239 s is not essential either for Ypt1p-mediated vesicular transport or as a timer to turn off Ypt1p-medi

240 the targeting of many proteins that use the vesicular transport pathway and thus favors its successf

241 to define a late-endosome-to-plasma-membrane vesicular transport pathway important in viral assembly.

242 The SNARE-mediated vesicular transport pathway plays major roles in synapti

243 evealed that iRGD coadministration induced a vesicular transport pathway that carried Au-labeled sili

244 alpha-COP binds to SMN, linking the COPI vesicular transport pathway to SMA.

245 t least partly through the inhibition of the vesicular transport pathway.

246 ctions of both NPC1 and Ptc involve a common vesicular transport pathway.

247 osphoinositides play key regulatory roles in vesicular transport pathways in eukaryotic cells.

248 we now rule out an essential role for known vesicular transport pathways in transporting the major y

249 f GTPases, acting as essential regulators of vesicular transport pathways.

250 Coat complexes sort protein cargoes into vesicular transport pathways.

251 Unlike the situation in conventional vesicular transport, precursor Ape1, along with its rece

252 st the induction of an autophagocytosis-like vesicular transport process during ectomycorrhizal inter

253 indings indicate that, if Rab24 functions in vesicular transport processes, it may operate through a

254 vesicular membranes necessary for long range vesicular transport processes.

255 cover an unexpected molecular link between a vesicular transport protein and a syndrome of autoimmuni

256 We have identified Rab8, a vesicular transport protein associated with trans-Golgi

257 A subset of the Arf1-COPI vesicular transport proteins also regulated droplet morp

258 Molecular analysis of vesicular transport proteins has revealed important info

259 Vesicular transport proteins package classical neurotran

260 n the current paradigm of cargo selection in vesicular transport, proteins to be sorted to other orga

261 on continued polarized secretion, suggesting vesicular transport provides a positive feedback signal

262 As a basis for the specificity of vesicular transport reactions, each step in the secretor

263 rane-association domains disrupts retrograde vesicular transport, recapitulating the BPAG1 null pheno

264 esults suggest that the function of Ypt1p in vesicular transport requires not only the GTP-bound form

265 However, vesicular transport requires PSD-95 palmitoylation to at

266 These data suggest that deregulation of vesicular transport results in reduced capacitative calc

267 er 60 distinct Rab GTPases regulate specific vesicular transport steps in the mammalian central vacuo

268 rstanding of membrane-localized processes in vesicular transport, such as membrane budding and fissio

269 ikely by compromising the development of the vesicular transport system for ACh preventing it from ac

270 ossess a pharmacopoeia of (1) the eukaryotic vesicular transport system, (2) immunity, and (3) previo

271 d PS2 partially co-localized to sites of the vesicular transport system.

272 in a variety of cellular processes including vesicular transport, the respiratory burst, and mitogene

273 to monensin, tamoxifen decreased the rate of vesicular transport though the recycling and secretory p

274 d that Pyk2 may be involved in regulation of vesicular transport through its interaction with Pap.

275 increase in tumor cGMP levels and increased vesicular transport through tumor capillaries, and could

276 t known for regulating membrane dynamics and vesicular transport; thus, we performed photobleaching e

277 reformed in human eosinophils for release by vesicular transport to contribute to immune responses.

278 Recent findings indicate that fungi use vesicular transport to deliver substances across their c

279 atory protein that links MICAL-L1.EHD1-based vesicular transport to dynein motors.

280 AnkX protein prevented microtubule-dependent vesicular transport to interfere with fusion of the L. p

281 and redistribute proteins after delivery by vesicular transport to neural cell plasma membranes.

282 for diverse cellular processes ranging from vesicular transport to nuclear envelope breakdown to mit

283 nt for their interdependent cellular role in vesicular transport to primary cilia.

284 reveal that BBS may be caused by defects in vesicular transport to the cilium.

285 ceptors, and quantitatively leave the ER via vesicular transport to the Golgi.

286 tic trafficking from the plasma membrane, or vesicular transport to the vacuole, has a smaller effect

287 Incoming human papillomavirus (HPV) utilize vesicular transport to traffic from the plasma membrane

288 s revealed that, in this zone, alteration of vesicular transport together with cytoskeleton dynamics

289 Myosin Va (MyoVa) mediates F-actin-based vesicular transport toward the plasma membrane and is fo

290 An unusually low rate of vesicular transport (transcytosis) has been identified a

291 ons and extremely low rates of transcellular vesicular transport (transcytosis).

292 icles are key components of the machinery of vesicular transport used by eukaryotic cells.

293 ve endoderm, suggesting that a deficiency in vesicular transport via early endosomes underlies the mu

294 Vesicular transport was not disrupted by filipin providi

295 cular mechanism of the EFA6/Arf6 function in vesicular transport, we searched for new EFA6 partners.

296 ilarly, normal sphingolipid biosynthesis and vesicular transport were required for optimal growth upo

297 GTP-binding proteins known for their role in vesicular transport, where they nucleate the assembly of

298 ing between eukaryotic compartments requires vesicular transport, wherein tethering provides the firs

299 wn to regulate early stages of intracellular vesicular transport, without proteasomal involvement.

300 cerevisiae that is temperature sensitive for vesicular transport, YopM failed to accumulate in the nu