ライフサイエンスコーパス: vesicular transporter

1 Likewise, KCs do not express a known vesicular transporter.

2 o identify the substrate binding site of the vesicular transporter.

3 nits GLR-1 and GLR-2 and the EAT-4 glutamate vesicular transporter.

4 (prt) that is structurally similar to known vesicular transporters.

5 l and are refilled with neurotransmitter via vesicular transporters.

6 the neuronal gamma-aminobutyric acid-glycine vesicular transporters.

7 naptic markers synaptophysin, SV2, glutamate vesicular transporter 1, and CTBP2 label foveal cones at

8 The distribution of the monoamine vesicular transporter 2 was shown by immunocytochemistry

9 quantal size can be regulated by changes in vesicular transporter activity.

10 re depends on the functional activity of the vesicular transporters and their efficient sorting to th

11 l first discuss the properties of C. elegans vesicular transporters and transporter mutants, and then

12 organelles immunoreactive for GABA, the GABA vesicular transporter, and the vesicular monoamine trans

13 Vesicular transporters are required for the storage of a

14 Vesicular transporters are responsible for the loading o

15 Vesicular transporters catalyze the filling of synaptic

16 pathway (e.g., receptor, uptake transporter, vesicular transporter, degradation enzymes).

17 We observe that changing the number of vesicular transporters expressed at hippocampal excitato

18 of synaptic differentiation, the predominant vesicular transporters expressed in neocortical neurons,

19 that this modulation of synaptic strength by vesicular transporter expression is endogenously regulat

20 Together, these findings underscore that vesicular transporter expression is used endogenously to

21 d by an increase in the levels of VAChT, the vesicular transporter for ACh, and confirm that there is

22 ar monoamine transporter VMAT2, which is the vesicular transporter for dopamine.

23 In addition, a recently identified vesicular transporter for GABA defines a novel family of

24 enzyme for GABA (GAD65/67) or the brainstem vesicular transporter for glutamate (VGLUT2).

25 his vesicular GABA transporter (VGAT) with a vesicular transporter for monoamines shows that there ar

26 the orphan Rxt1/NTT4 protein functions as a vesicular transporter for proline, glycine, leucine, and

27 inity for histamine, and the identity of the vesicular transporter for this monoamine is uncertain.

28 ptic endings of DAergic cells contained both vesicular transporters for DA [vesicular monoamine trans

29 we found that some mesoaccumbens fibers have vesicular transporters for dopamine (VMAT2) in axon segm

30 rons in the dorsal raphe nucleus, expressing vesicular transporters for GABA or glutamate (hereafter,

31 Although the vesicular transporters for monoamines and acetylcholine

32 One family of proteins includes vesicular transporters for monoamines and acetylcholine.

33 r cloning has recently demonstrated that the vesicular transporters for monoamines and ACh show stron

34 )(2)) within TMEM163 that encodes a probable vesicular transporter in nerve terminals.

35 [vesicular GABA/glycine transporter (VGAT)] vesicular transporters in postnatal retina.

36 revealed colocalization of ACh and glutamate vesicular transporters in synaptic vesicles (SVs) in the

37 and GABA/glycine (known as VIAAT+ or VGAT+) vesicular transporters in the Mo5, Mo7, Amb, and Mo12.

38 In unc-46 mutants, the vesicular transporter is not found specifically in synap

39 Vesicular transporters mediate the packaging of neurotra

40 VGLUT2 is clearly the predominant vesicular transporter mRNA found in the hypothalamus; ri

41 s expressed in neurons that lack other known vesicular transporters or neurotransmitters, it may defi

42 ion of available glutamate and the number of vesicular transporters participating in loading.

43 Vesicular transporters play an essential role in the pac

44 Vesicular transporters regulate the amount and type of n

45 hetic enzyme glutamic acid decarboxylase and vesicular transporter, respectively .

46 nce indicating that Rxt1/NTT4 functions as a vesicular transporter selective for proline, glycine, le

47 Two of the four classes of vesicular transporters so far identified (VAChT and VGAT

48 Some neurons lack known vesicular transporters, suggesting additional neurotrans

49 phan hydroxylase, and cat-1, which encodes a vesicular transporter that loads serotonin into synaptic

50 ks any of the known characteristics of other vesicular transporters, these results suggest that certa

51 n when expressed in the same neuron, the two vesicular transporters thus target to distinct populatio

52 dy takes advantage of the specificity of the vesicular transporters to afford the first detailed map

53 tion, dopamine vesicles utilize a cascade of vesicular transporters to dynamically increase the vesic

54 eles of either the glutamate or GABA/glycine vesicular transporters to selectively eliminate glutamat

55 The vesicular transporters translocate the first proton usin

56 However, the presence of the vesicular transporter (vesicular acetylcholine (ACh) tra

57 plus its synthetic enzyme (GAD(65)) and its vesicular transporter (VGAT).

58 g a mouse that lacks the glutamate-selective vesicular transporter VGLUT1, we find that glutamate alo

59 cat retina that contain glutamate, plus its vesicular transporter (VGLUT1), and GABA, plus its synth

60 reas IB4-labeled afferents had low levels of vesicular transporters, VGLUT1 (5%) or VGLUT2 (21%).

61 The mouse glutamate vesicular transporter VGLUT2 has recently been character

62 ontrols, as were the levels of the glutamate vesicular transporter vGlut2.

63 In contrast, the synaptic vesicular transporters VGLUT2 or GAD7 labeled much large

64 re available for each of the four C. elegans vesicular transporters, which has permitted a careful ev