ライフサイエンスコーパス: vesiculation

1 is required solely for EGF-stimulated inward vesiculation.

2 t may be required for a late stage in inward vesiculation.

3 shes the effect of EGF stimulation on inward vesiculation.

4 to thrombin rather than by inducing platelet vesiculation.

5 smembrane phospholipid movement and membrane vesiculation.

6 ty in the cytoplasm, with no plasma membrane vesiculation.

7 3, and the need for PLD1 activation in Golgi vesiculation.

8 2 and phosphatidic acid (PA) during membrane vesiculation.

9 mitosis, with little or no fragmentation and vesiculation.

10 echanically induced membrane deformation and vesiculation.

11 activated alpha subunit, that triggers Golgi vesiculation.

12 f membrane lipids and proteins and decreased vesiculation.

13 spholipid asymmetry and results in decreased vesiculation.

14 ll's outer leaflet upon in vitro storage and vesiculation.

15 ired for ESCRT-III disassembly and endosomal vesiculation.

16 ocesses such as endocytosis, tubulation, and vesiculation.

17 externalization, including cell division and vesiculation.

18 have unique roles in the mechanisms of COPII vesiculation.

19 f the C5b-9 complexes by endocytosis and exo-vesiculation.

20 over-expression of Cav-1 increased C5b-9 exo-vesiculation.

21 s that may correspond to regions of membrane vesiculation.

22 nto evaluating mechanisms for outer membrane vesiculation.

23 erize the process of liposome tubulation and vesiculation.

24 n MAC deposition and MAC-mediated damage and vesiculation.

25 ses during Golgi disassembly: unstacking and vesiculation.

26 physical design principles to ensure robust vesiculation against opposing forces like membrane tensi

27 h are disintegrated by membrane blebbing and vesiculation, aging lens fiber cells are compressed into

28 d into tubular extensions that later undergo vesiculation, allowing transport vesicles to move along

29 ion of purified EHD proteins to reconstitute vesiculation allows us to assess the ability of each pro

30 e disentangled by these chaperons to achieve vesiculation and acrosomal contents release.

31 after protracted loss of OM material through vesiculation and blebbing at cell-division sites and com

32 taining by immunofluorescence assay, and the vesiculation and breakdown of the internal parasite ultr

33 atric disorders and other conditions, aging, vesiculation and cell division).

34 ew fiber growth was disordered and displayed vesiculation and density variations.

35 Inner-membrane vesiculation and dissociation of ATP synthase dimers wou

36 more versatile function of these proteins in vesiculation and endocytosis beyond their role as scaffo

37 field and experimental observations of magma vesiculation and fragmentation resulting from heating (r

38 nsity on self-forming Percoll gradients upon vesiculation and in vitro "aging." Uptake of vesiculated

39 is a ubiquitous eukaryotic membrane budding, vesiculation and internalization process fulfilling nume

40 We further demonstrated that vesiculation and plasma membrane enclosure at the site o

41 e apical membrane of damaged cells exhibited vesiculation and shedding of microvilli.

42 ns with the vascular systems through altered vesiculation and TF shedding.

43 has the intrinsic ability to induce membrane vesiculation and to incorporate NC-like structures into

44 ar mechanism of ENTH-domain-induced membrane vesiculation and tubulation and the implications of the

45 Liposome remodeling processes (e.g., vesiculation and tubulation) due to N-BAR domain interac

46 new insight for their differential roles in vesiculation and tubulation, respectively.

47 embrane curvature induction is different for vesiculation and tubulation, these data also explain why

48 taneous curvature, and membrane stiffness on vesiculation and vesicle size distribution were investig

49 multiple points with the acrosomal membrane (vesiculation) and syntaxin and VAMP are shed with the re

50 , band 3, triggers membrane destabilization, vesiculation, and fragmentation, we discovered a SH2 sig

51 creased cell wall apposition and cytoplasmic vesiculation, and induction of callose deposition.

52 BB, including membrane tethering defects, MV vesiculation, and membrane shedding.

53 level surface fibrinogen retention, membrane vesiculation, and procoagulant activity.

54 r the sequence of events leading to budding, vesiculation, and secretion; and PxB-mediated transfer b

55 f the ENTH domain of epsin leads to liposome vesiculation, and that epsin is required for clathrin-co

56 ets treated with RO318220 suggested platelet vesiculation as a result of RO318220 treatment; however,

57 onally compromised GAPDH identifies enhanced vesiculation as a self-protective mechanism in ex vivo a

58 x in nuclear envelope breakdown, implicating vesiculation as an important step.

59 sed on membrane integrity and by cytoplasmic vesiculation as evidence of piecemeal degranulation.

60 Our novel vesiculation assay and in vitro electron microscopy anal

61 It undergoes extensive vesiculation at the onset of mitosis and its reassembly

62 of recombinant proteins, using a hypertonic vesiculation buffer containing chloride salts and no for

63 ossible roles of these components in driving vesiculation by constructing a quantitative model of the

64 ysis of the energetics and thermodynamics of vesiculation by recourse to nonlinear elasticity, taking

65 The extent of vesiculation by these proteins and vesicle size depend o

66 OP-I recruitment, the role of COP-I in Golgi vesiculation caused by expression of the dominant activa

67 c14p, which also suppresses the uncontrolled vesiculation caused by the cytosolic subfraction.

68 These experiments suggest that vesiculation contributes to alterations in membrane lipi

69 AR domain of Pacsin and mutagenesis studies, vesiculation could be linked to the presence of unique s

70 erturbed in the absence of Clc, resulting in vesiculation defects.

71 ation of the process of C5b-9 removal by exo-vesiculation demonstrated that inhibition of Cav-1 and c

72 phatidyl-choline were monitored for age- and vesiculation-dependent changes in cell density, membrane

73 and was preceded by PV membrane indentation, vesiculation, disruption, and, surprisingly, stripping o

74 Endophilin, which participates in membrane vesiculation during receptor-mediated endocytosis, is a

75 dynamin (Dyn2) has been implicated in Golgi vesiculation during secretion, we tested whether inhibit

76 by Src kinase regulates Golgi integrity and vesiculation during the secretory process.

77 Mutations that cause increased vesiculation enhance bacterial survival upon challenge w

78 rce from actin polymerization enables robust vesiculation even at high membrane tensions.

79 nesis and for a series of "reverse topology" vesiculation events.

80 results demonstrate VP40 selectively induces vesiculation from membranes containing phosphatidylserin

81 erefore, that the mechanism of AP-3-mediated vesiculation from neuroendocrine endosomes requires the

82 g proteins are required for the AP2-mediated vesiculation from the plasma membrane, but not from endo

83 of cPLA2alpha did not increase the endosomal vesiculation, implying a requirement for additional fact

84 The NEC drives nuclear envelope vesiculation in cells, but the precise budding mechanism

85 binant O-PS biosynthesis is coordinated with vesiculation in laboratory strains of Escherichia coli t

86 during HSV-1 infection and nuclear envelope vesiculation in NEC-transfected cells.

87 peptide release supports a dynamic role for vesiculation in NTHI pathogenesis and clinically relevan

88 ation of AlgU, since stress caused increased vesiculation in strains lacking algU.

89 Erythrocyte vesiculation in vitro produced MPs loaded with heme.

90 t mitotic Golgi breakdown proceeds by direct vesiculation independent of the ER.

91 vature as it tubulates liposomes and induces vesiculation into giant unilamellar vesicles, effects th

92 We conclude that ARF-mediated vesiculation into synaptic vesicle-sized organelles uses

93 We find that IQ-mediated Golgi vesiculation is inhibited by G alpha(s)-GDP and G alpha(

94 Vesiculation is mediated by the COPI budding machinery A

95 stops membrane disassembly, suggesting that vesiculation is necessary.

96 N-BAR spontaneous curvature fields, whereas vesiculation is only observed with isotropic N-BAR spont

97 Here, we show that Golgi vesiculation is required for progression to metaphase.

98 This inward vesiculation is specific for AnxA2 and not shared with o

99 protein involved in membrane tubulation and vesiculation, is essential for successful cytokinesis.

100 lation mutant strains did not correlate with vesiculation levels, demonstrating that vesicle producti

101 further mechanistic studies to identify the vesiculation machinery that regulates OMV secretion and

102 a during ascent strongly controls degassing, vesiculation, magma strength and the effusive-explosive

103 null mutants were recovered, suggesting that vesiculation may be a fundamental characteristic of gram

104 orks of concatenated vesicle buds by a novel vesiculation mechanism.

105 Such changes, rather than vesiculation mechanisms, also underlie the redistributio

106 ess, and growth characteristics of the novel vesiculation mutant strains did not correlate with vesic

107 Only a few low-vesiculation mutants and no null mutants were recovered,

108 Prospects of vesiculation occurring during splenic flow of erythrocyt

109 Our findings reveal that IQ-mediated Golgi vesiculation occurs through activation of heterotrimeric

110 es highlight the importance of annexin A2 in vesiculation of a population of Atg16L-positive structur

111 f small areas of plasma membrane followed by vesiculation of apposed membranes.

112 fier cPLA2alpha and EHD1 are involved in the vesiculation of CD59-containing endosomes.

113 Budding and vesiculation of erythrocyte membranes occurs by a proces

114 sequence seen during spontaneous inside-out vesiculation of erythrocyte membranes suggests that the

115 of PLD1, recruitment of COP-I to Golgi, and vesiculation of Golgi in cells are functionally separabl

116 studies support a role for cPLA2alpha in the vesiculation of GPI-AP-containing membranes, using endog

117 nerate sufficient heat to induce melting and vesiculation of hydrated silicic magma.

118 ant unilamellar vesicles by inducing massive vesiculation of liposomes.

119 the mitochondrial membrane potential, induce vesiculation of mitochondria, and induce elevated poly (

120 esulting complement activation initiates the vesiculation of myelin.

121 They cause dramatic vesiculation of new plasma membranes, and destabilize th

122 icular transport defects including unpacking/vesiculation of rhabdomeres, endocytosis of novel vesicl

123 lesion detectable by electron microscopy was vesiculation of rod discs, followed by disruption of out

124 nsport carriers, and to prevent uncontrolled vesiculation of TGN during protein transport.

125 mals (3/12) had APCs that involved prominent vesiculation of the anterior cortex.

126 bility, abnormal morphology, and spontaneous vesiculation of the cells; and 4) the above on/off rates

127 By reconstituting the IQ-mediated vesiculation of the Golgi apparatus in permeabilized cel

128 and their overactivation results in complete vesiculation of the Golgi apparatus.

129 spholipase C- and protein kinase D-dependent vesiculation of the Golgi in HeLa cells; Golgi-targeted

130 a marine sponge metabolite, causes complete vesiculation of the Golgi stacks.

131 t of proteins to coated pits and helps drive vesiculation of the lipid bilayer.

132 losed that resiniferatoxin treatment induced vesiculation of the mitochondria and the endoplasmic ret

133 glycerol, caused by itself an indiscriminate vesiculation of uncoated Golgi membranes that could be s

134 a morphological assay that Rab2 Q65L caused vesiculation of VTCs that accumulated at 15 degrees C.

135 ll measurements to investigate the impact of vesiculation on the reduction in volume, Hb mass, and me

136 l activity from a non-random process such as vesiculation or bleb formation: channel inactivation by

137 c Golgi breakdown in vivo proceeds by direct vesiculation or involves fusion with the endoplasmic ret

138 amin uses GTP hydrolysis physically to drive vesiculation; others support the view that dynamin acts

139 Here we review the advantage of vesiculation, particularly in a nonpathogenic context, a

140 he ER at M-phase as the result of a two-step vesiculation pathway involving ER-Golgi fusion followed

141 catalyse many of the essential steps in the vesiculation pathway.

142 swelling of endoplasmic reticulum and Golgi vesiculation preceding most nuclear changes and mitochon

143 The most widely used vesiculation procedure relies on formaldehyde and dithio

144 into vesicles for removal indicates that the vesiculation process can act to selectively eliminate un

145 vesicles prepared by a spontaneous, one-step vesiculation process is shown to be by a low affinity sy

146 ovesiculation of the external hemileaflet, a vesiculation process promoted by the detergent environme

147 be generated from endosomes by a sorting and vesiculation process that requires the heterotetrameric

148 large deformation that may arise during the vesiculation process.

149 in (EHD) ATPase proteins are involved in the vesiculation process.

150 A clearer understanding of such vesiculation processes holds promise for better elucidat

151 The fusing membranes dispersed by vesiculation, rather than simple unfolding of the conjoi

152 rosomal vesicle membrane at multiple points (vesiculation) results in the release of SNAP-25 with the

153 ltiple, independent measurements of membrane vesiculation revealed that fission became spontaneous as

154 A quantitative assay for vesiculation reveals an antagonistic relationship betwee

155 vesicles of MVB after EGF-stimulated inward vesiculation, suggesting that it may be required for a l

156 dings are consistent with reported trends in vesiculation that are believed to occur in cases of vari

157 ells leads to an increase in plasma membrane vesiculation that is relatively resistant to energy depl

158 st pathways for further study of erythrocyte vesiculation that point to the criticality of understand

159 ncreased levels of lipopolysaccharide and OM vesiculation that ultimately undermine the integrity of

160 re enhanced by bubble nucleation and growth (vesiculation) that reduce the density of magma.

161 Our current studies showed that during vesiculation the skeleton did not fragment but rather re

162 (subcellular fractionation, plasma membrane vesiculation to isolate pure plasma membrane fractions,

163 h reversal of staining to marked cytoplasmic vesiculation to loss of cellular membrane integrity with

164 ivity, DNA fragmentation, or plasma membrane vesiculation, typical characteristics of apoptosis.

165 t the critical membrane size for spontaneous vesiculation was correlated with membrane thickness, and

166 The degree of membrane vesiculation was more than 50% lower in EASs than in Ads

167 f envelope proteins resulting from decreased vesiculation was toxic and contributed to the growth def

168 latory mechanisms and physiological basis of vesiculation, we conducted a screen in Escherichia coli

169 f endoplasmic reticulum (ER) aggregation and vesiculation were observed in BBSV-infected Nicotiana be

170 serves a role similar to that of EHD1 in TRE vesiculation, whereas EHD2, despite being capable of ves

171 EHD1 and EHD4 are primarily in TRE membrane vesiculation, whereas EHD3 is a membrane-tubulating prot

172 EHD1 induces membrane vesiculation, whereas EHD3 supports TRE biogenesis and/o

173 nd cholesterol depletion abrogated C5b-9 exo-vesiculation, whereas, over-expression of Cav-1 increase

174 ring is independent of endoplasmic reticulum vesiculation, which occurs only at ionomycin concentrati

175 ion increases both MVB biogenesis and inward vesiculation within EGFR-containing MVBs.

176 s, suggesting that MVB biogenesis and inward vesiculation within MVB are mediated by separate mechani