ライフサイエンスコーパス: vestibular hair cell

1 cholinergic efferents innervating peripheral vestibular hair cells.

2 ssion, reminiscent of two subtypes of native vestibular hair cells.

3 cholinergic efferents innervating peripheral vestibular hair cells.

4 mechanotransduction complex in auditory and vestibular hair cells.

5 the tips of stereocilia of both cochlear and vestibular hair cells.

6 l mouse cochlear hair cells but persisted in vestibular hair cells.

7 ve distinct functional roles in cochlear and vestibular hair cells.

8 ctures at the apical surface of auditory and vestibular hair cells.

9 atment caused apoptosis of both auditory and vestibular hair cells.

10 f data concerning BK expression in mammalian vestibular hair cells.

11 esponse, and normal transduction currents in vestibular hair cells.

12 myosin-1c is required for fast adaptation in vestibular hair cells.

13 tips of the stereocilia of the cochlear and vestibular hair cells.

14 signaling events that regulate the death of vestibular hair cells.

15 nner hair cells, spiral ganglion neurons and vestibular hair cells.

16 in the apoptotic destruction of auditory and vestibular hair cells.

17 h1-null mice failed to generate cochlear and vestibular hair cells.

18 ptation of mechanoelectrical transduction in vestibular hair cells.

19 on, regeneration, and apoptosis of mammalian vestibular hair cells.

20 upport to calyceal synaptic contact with the vestibular hair cell and that Caspr is required for the

21 Vestibular hair cells and afferents were counterstained

22 detected in stereocilia of both cochlear and vestibular hair cells and also along the apical surface

23 ly as embryonic day 16.5 in the auditory and vestibular hair cells and associated ganglionic neurons,

24 form in hair bundles of outer hair cells and vestibular hair cells and is the predominant PMCA of hai

25 enrichment of relatively pure populations of vestibular hair cells and non-sensory cells including su

26 y hair cells and deafness in mice, a loss of vestibular hair cells and overt behavioral defects chara

27 ted in maturing (myosin VIIA immunoreactive) vestibular hair cells and subsequently in the underlying

28 are significant signaling regions of type II vestibular hair cells and suggest that type II hair cell

29 used dual patch-clamp recordings from turtle vestibular hair cells and their afferent neurons to show

30 Brn-3c protein is found only in auditory and vestibular hair cells, and the Brn-3a and Brn-3b protein

31 In mammals, type I and II vestibular hair cells are defined by their shape, contac

32 Significantly, adult pRb(-/-) vestibular hair cells are functional, and pRb(-/-) mice

33 zd9, whereas the main receptors expressed in vestibular hair cells are Fzd1 and Fzd7, in addition to

34 Our results suggest that cochlear and vestibular hair cells are the primary regulators of auto

35 Auditory and vestibular hair cell bundles exhibit active mechanical o

36 he M-like conductances in mouse auditory and vestibular hair cells can include KCNQ4 subunits and may

37 -rich stereocilia elongation in auditory and vestibular hair cells, causing deafness and balance defe

38 located in the apical region of cochlear and vestibular hair cells, consists of alternating, cross-li

39 s spectrometry shows that bundles from chick vestibular hair cells contain a complete set of proteins

40 resonance seen in many types of auditory and vestibular hair cells contributes to frequency selectivi

41 development of hair bundles in cochlear and vestibular hair cells, controlling hair bundle morphogen

42 In a wild-type mouse, during auditory and vestibular hair cell development, myosin XVa appears at

43 Accordingly, whole cell currents of vestibular hair cells did not differ between genotypes.

44 Lesions of vestibular hair cells disrupt the characteristic firing

45 ects reflect a complete loss of auditory and vestibular hair cells during the late embryonic and earl

46 Both type I and type ll vestibular hair cells express the alpha9 and alpha10 sub

47 Cochlear and vestibular hair cells from PCDH15-deficient mice also sh

48 nd that, whereas the basolateral membrane of vestibular hair cells from the frog saccule extrudes H+

49 We conclude that HCN1 contributes to vestibular hair cell function and the sense of balance.

50 Vestibular hair cells have a distinct planar cell polari

51 Type I vestibular hair cells have large K+ currents that, like

52 and ultrastructure of efferent terminals on vestibular hair cells in alpha9, alpha10, and alpha9/10

53 ibe unique morphological features of type II vestibular hair cells in mature rodents (mice and gerbil

54 ion mixture resulted in the return of type 1 vestibular hair cells in ototoxin-damaged cristae, and i

55 sition of the kinocilium is reversed between vestibular hair cells in the cristae of the semicircular

56 Vestibular hair cells in the inner ear encode head movem

57 often result in degeneration of cochlear and vestibular hair cells in the inner ear.

58 The molecular diversity of vestibular hair cells indicates a functional diversity t

59 cochlear outer hair cells and some groups of vestibular hair cells, indicating that Jag1 is required

60 type I hair cell, and the basolateral type I vestibular hair cell is NR-1 immunoreactive.

61 Myo1c to stereociliary tips of cochlear and vestibular hair cells is disrupted by treatments that br

62 Additionally, Ocm immunoreactivity in vestibular hair cells is present as early as E18 and is

63 te the effect of hydrostatic pressure on the vestibular hair cells located in the labyrinth of the do

64 al yet distinct roles of pRb in cochlear and vestibular hair cell maturation, function, and survival

65 o suggest that persistent TMC2 expression in vestibular hair cells may preserve vestibular function i

66 cadherin 15 has been described for a teleost vestibular hair-cell model and mammalian organ of Corti

67 ning (i.e., light paired with stimulation of vestibular hair cells) modifies the kinetics of presynap

68 spiral and vestibular ganglia, inner ear and vestibular hair cell neurons in the vestibuloacoustic sy

69 We transfected auditory and vestibular hair cells of organotypic cultures generated

70 I(h) has been characterized in vestibular hair cells of the inner ear, but its molecula

71 ble intracellular damage to the auditory and vestibular hair cells of the inner ear.

72 tional co-activator regulated by miR-135b in vestibular hair cells of the mouse inner ear as well as

73 ransduction is impaired in cochlear, but not vestibular, hair cells of early postnatal Vlgr1/del7TM m

74 ted in a significant and age-related loss of vestibular hair cells only in the saccule.

75 monly associated with damage to cochlear and vestibular hair cells or neurons.

76 t expression patterns: some are specific for vestibular hair cells, others for cochlear hair cells, a

77 component, to trace development of the SO in vestibular hair cells over the first postnatal week.

78 nd PMCA2 isozymes holds for rat auditory and vestibular hair cells; PMCA2a is the only PMCA isoform i

79 pe of CNGA3 transcript in a purified teleost vestibular hair cell preparation with immunolocalization

80 Treatment with GF I significantly enhanced vestibular hair cell renewal in ototoxin-damaged utricle

81 Sensory transduction in auditory and vestibular hair cells requires expression of transmembra

82 t and mechanical stimulation of the animal's vestibular hair cells resulted in an increase in the exc

83 efined immunolocalization in rat and chicken vestibular hair cells showed that CLIC5 is limited to th

84 Confocal imaging of isolated bullfrog vestibular hair cells shows that the bundle membrane seg

85 ings of light and presynaptic stimulation of vestibular hair cells (simulating light-rotation pairing

86 the localization of BK channels in mammalian vestibular hair cells, specifically in rat vestibular ne

87 coupled receptors as a result of presynaptic vestibular hair cell stimulation.

88 n inner hair cells and in type I and type II vestibular hair cells suggests a functional role in hair

89 In contrast, many pRb(-/-) vestibular hair cells survive and continue to divide in

90 ctions, owing to the failure of cochlear and vestibular hair cells to differentiate properly.

91 vey excitatory stimuli from inner ear type I vestibular hair cells to postsynaptic calyx nerve termin

92 However, it is unclear whether vestibular hair cells undergo similar degeneration in co

93 ethods to demonstrate that utricular type II vestibular hair cells undergo turnover in adult mice und

94 carinic receptors (mAChRs), are expressed by vestibular hair cells (VHCs).

95 In frog and mouse vestibular hair cells, we found that the rate of fast ad

96 s, a robust model for mammalian auditory and vestibular hair cells, we identified a urea-thiophene ca

97 sing the Brn 3.1 knockout mouse, which lacks vestibular hair cells, we recently described a major rol

98 found at calyx terminals ensheathing type I vestibular hair cells where it may be localized pre- or

99 oad punctate cytoplasmic distribution in the vestibular hair cells, whereas it was detected in the en