ライフサイエンスコーパス: vibriobactin

1 and norspermidine--produce the iron chelator vibriobactin.

2 xazolinyl) and bis(thiazolinyl) analogues of vibriobactin.

3 ses and is necessary for the biosynthesis of vibriobactin.

4 dary amine, also catalyzed by VibF, to yield vibriobactin.

5 owed the utilization of enterobactin but not vibriobactin.

6 port of heme and of the catechol siderophore vibriobactin.

7 The ViuPDGC system transports both vibriobactin and enterobactin in Escherichia coli.

8 ate transport of haemin and the siderophores vibriobactin and ferrichrome.

9 transport systems, including uptake of haem, vibriobactin and ferrichrome.

10 arrier proteins from VibB of Vibrio cholerae vibriobactin and HMWP2 of Yersinia pestis yersiniabactin

11 one of three acylations required for mature vibriobactin, and its formation confirms VibH's role in

12 is and transport of the catechol siderophore vibriobactin, and transport of several siderophores that

13 ss, Vibrio cholerae produces the siderophore vibriobactin as well as a number of iron-induced outer m

14 Vibriobactin biosynthesis in vitro has thus been accompl

15 d characterize V. cholerae genes involved in vibriobactin biosynthesis, we constructed a genomic cosm

16 Of the four genes positively implicated in vibriobactin biosynthesis, we have here expressed, purif

17 n, and its formation confirms VibH's role in vibriobactin biosynthesis.

18 V. cholerae VibA catalyzes an early step in vibriobactin biosynthesis.

19 obactin transport and mapped them within the vibriobactin biosynthetic gene cluster.

20 this mutant was unable to synthesize ferric vibriobactin but was able to utilize exogenous sideropho

21 enterobactin cluster and the Vibrio cholera vibriobactin cluster, were shuffled to produce a new sid

22 nents from siderophore NRPSs that synthesize vibriobactin, enterobactin, yersiniabactin, pyochelin, a

23 However, a mutant defective in the vibriobactin, Fbp, and Feo systems was not attenuated in

24 ibrio cholerae uses the catechol siderophore vibriobactin for iron transport under iron-limiting cond

25 d; IgG monoclonal antibodies specific to the vibriobactin fragment of the BSA and OVA conjugates were

26 Our data indicate that the vibriobactin genes are clustered, like the E. coli enter

27 a conclusion confirmed with the formation of vibriobactin in a C1-deficient system.

28 o cholerae secretes the catechol siderophore vibriobactin in response to iron limitation.

29 The Vibrio cholerae siderophore vibriobactin is biosynthesized from three molecules of 2

30 Vibriobactin is structurally similar to enterobactin, th

31 Vibriobactin [N(1)-(2,3-dihydroxybenzoyl)-N(5),N(9)-bis[

32 d when compared by circular dichroism to the vibriobactin NRPS VibH, a naturally free-standing C doma

33 The iron-chelating catechol siderophore vibriobactin of the pathogenic Vibrio cholerae is assemb

34 The iron-chelating peptide vibriobactin of the pathogenic Vibrio cholerae is assemb

35 This strain was unable to produce vibriobactin or DHBA, confirming that in V. cholerae Vib

36 osomal DNA downstream of the Vibrio cholerae vibriobactin outer membrane receptor, viuA, and the vibr

37 Comparative rates of vibriobactin production, coupled with dissociation const

38 talytically inactive and is not required for vibriobactin production.

39 port requires TonB and is independent of the vibriobactin receptor ViuA.

40 of the mature protein of the Vibrio cholerae vibriobactin receptor, ViuA.

41 mutant with a cloned vibF fragment restored vibriobactin synthesis to normal.

42 n (Cy1-Cy2-A-C1-PCP-C2) enzyme VibF from the vibriobactin synthetase assembly line, which contains th

43 domain (Cy1-Cy2-A-C1-PCP-C2) VibF subunit of vibriobactin synthetase has previously been shown to be

44 Vibriobactin synthetase is an unusual NRPS in that all i

45 its PCP with L-threonine, and together with vibriobactin synthetase proteins VibE (adenylation) and

46 ptide synthetase (NRPS) VibF, a component of vibriobactin synthetase, has been heterologously express

47 We have identified genes for vibriobactin transport and mapped them within the vibrio

48 actin outer membrane receptor, viuA, and the vibriobactin utilization gene, viuB, was recovered from

49 s reduced, but did not completely eliminate, vibriobactin utilization.

50 in the utilization of both enterobactin and vibriobactin (VCA0227-0230).

51 A vibriobactin (VIB) analogue, with a thiol tether, 1-(2,3

52 It transports the catechol siderophores vibriobactin, which it synthesizes and secretes, and ent