ライフサイエンスコーパス: vibrissa

1 n when inhibition was evoked from a surround vibrissa.

2 ceiving the main signals from the stimulated vibrissa.

3 ortical column appropriate for the deflected vibrissa.

4 d for motion toward their preferred surround vibrissa.

5 stically significant increase of LCGU in the vibrissa activated C3 barrel, and l-NA treatment did not

6 excitatory responses evoked by physiological vibrissa afferent stimulation were reduced by LY382884 a

7 f the signals elicited by deflection of each vibrissa alone.

8 ween the horizontal angle of contact of each vibrissa and every possible (pitch, distance, and yaw) c

9 Lrp4 and Wise mutants also share defects in vibrissa and hair follicle development, suggesting that

10 1 expression seen in the sebaceous glands of vibrissa and hair follicles in transgenic lines harborin

11 cited by the confluence of touch by a single vibrissa and the phase of vibrissa motion in the whisk c

12 yielded responses to deflection of a single vibrissa, and a significantly (P < 0.001) higher percent

13 ibrissa pathway, such integration across the vibrissa array strongly shapes the coding of spatiotempo

14 ificantly for recordings outside the primary vibrissa barrel column, providing additional evidence fo

15 ime-varying forces and bending moment at the vibrissa base during both noncontact (free-air) whisking

16 d experimental control in studies related to vibrissa-based neuronal circuitry.

17 rhythmic neuronal activity that accompanies vibrissa-based sensation, in rats, transiently locks to

18 ile whisking synchronized to sniffing serves vibrissa-based touch [6, 15, 16].

19 Vibrissa-based touch in rodents involves stereotypic, rh

20 en breathing and the sensations of smell and vibrissa-based touch.

21 nst an object, the intrinsic dynamics of the vibrissa can be as large as many of the mechanical effec

22 c dysfunction in the relay nuclei of the rat vibrissa circuit follows traumatic brain injury (TBI).

23 and provides strong modulation of signals of vibrissa contact.

24 or arteriole vs. venous blood within primary vibrissa cortex of awake, head-fixed mice.

25 receptive field, and arrives within 25 ms of vibrissa deflection.

26 present in large quantities in cultured rat vibrissa dermal papilla cells but undetectable in cultur

27 uctions in slope and increases in latency of vibrissa-evoked field potentials 3 days after injury.

28 derlying the slow and fast components of the vibrissa-evoked response.

29 scillations (FOs; > 200 Hz), superimposed on vibrissa-evoked slow potentials, may support rapid senso

30 in Shh -/- skin grafts, as well as cultured vibrissa explants treated with cyclopamine to block Shh

31 ic/GABAergic cells that rhythmically inhibit vibrissa facial motoneurons.

32 , we labeled neurons synapsing directly onto vibrissa facial motor neurons (vFMNs).

33 ly determine the horizontal angle at which a vibrissa first touches an object, and we therefore asked

34 of the human Lef-1 promoter during the hair/vibrissa follicle and sebaceous gland formation.

35 Using the vibrissa follicle as our model, we isolated follicle seg

36 Rat vibrissa follicle clonogenic keratinocytes, closely rela

37 patterns of Lef-1 expression during hair and vibrissa follicle development.

38 These data suggest that the vibrissa follicle is a in vitro good model system with w

39 , each originating from melanocytes within a vibrissa follicle rather than at the graft edge.

40 riptional targets of Trps1 in the developing vibrissa follicle, we performed microarray hybridization

41 s of guard hairs and inner conical bodies of vibrissa follicle-sinus complexes.

42 hair follicle progenitors in the developing vibrissa follicle.

43 of the whisker pad is noted, both around the vibrissa follicles and along the intervibrissal epidermi

44 In this investigation, adult rat vibrissa follicles for which growth in culture is limite

45 We have isolated vibrissa follicles from 12 d old rats and confirmed by h

46 in morphology that suggest that cultured rat vibrissa follicles retain cyclical activity in vitro.

47 endings) in the same target (Merkel cells of vibrissa follicles).

48 sae, the structure and innervation of facial vibrissa follicles, body hair follicles, and intervening

49 r anagen re-entry, and formation of compound vibrissa follicles.

50 ssage RNA is highly abundant in cultured rat vibrissa FP cells, can be detected at very low levels in

51 We conjecture that resonance properties in vibrissa, hypoglossal, and potentially other motoneurone

52 rom rats trained to rhythmically sweep their vibrissa in search of a target.

53 e a model for the rapid integration of multi-vibrissa input.

54 te for rapid excitatory and inhibitory multi-vibrissa interactions.

55 ude, latency, and precision induced by cross-vibrissa interactions.

56 this issue of Neuron that touch by a single vibrissa leads to a rapid depolarization of primary sens

57 Variation in vibrissa length predicted motion mean frequencies, inclu

58 orienting response to stimulation of unique vibrissa-like body hairs that are widely spaced over an

59 Consistent with a model of vibrissa mechanics, optical measurements of vibrissae re

60 e vibrissa motor cortex to drive spiking and vibrissa motion in awake mice when excited with red ligh

61 touch by a single vibrissa and the phase of vibrissa motion in the whisk cycle; different units have

62 uscle activity leads to an enhanced range of vibrissa motion than would be available from the intrins

63 between instantaneous velocity and timing of vibrissa motion, finding a strong interaction between an

64 i, reflecting the resonance amplification of vibrissa motion.

65 ged the nature of information conveyed about vibrissa motion.

66 rized the electrophysiological properties of vibrissa motoneurones (vMNs) in rat.

67 ory pathways from vibrissa sensory inputs to vibrissa motoneurons in the facial nucleus.

68 2+ excitatory projection neurons involved in vibrissa motor control.

69 ion, spike trains of single units in primary vibrissa motor cortex report the absolute angle of vibri

70 We used ReaChR expressed in the vibrissa motor cortex to drive spiking and vibrissa moti

71 a context-dependent change in the pattern of vibrissa movement during tactile exploration.

72 t in which bilateral or ipsilateral (intact) vibrissa movement predominated; (3) in both hemispheres

73 trimmed group, an abnormal pattern of evoked vibrissa movement was evident in which bilateral or ipsi

74 r-to-muscle circuit for positive feedback in vibrissa movement.

75 he vibrissae to the motoneurons that control vibrissa movement.

76 The rhythmic vibrissa movements are induced by local injection of a g

77 second-order sensorimotor loops that control vibrissa movements by rodents.

78 This protocol produces coordinated rhythmic vibrissa movements that are sustained for several hours

79 us firing during complex patterns of ongoing vibrissa movements that may ensure transmission of prefe

80 or the pharmacological induction of rhythmic vibrissa movements that mimic exploratory whisking.

81 Precise vibrissa movements were evoked by expressing ReaChR in t

82 , and coordination of bilaterally homologous vibrissa movements.

83 e trigeminal loop provides an enhancement of vibrissa muscle tone upon contact during active touch.

84 at provides positive sensory feedback to the vibrissa musculature during simulated whisking and conta

85 nucleus motoneurons that directly innervate vibrissa musculature.

86 al enhancement in functional activity of the vibrissa neurons at different somatosensory nuclei as ra

87 ment or VEGF blockade were observed in mouse vibrissa organ cultures, which lack a functional vascula

88 he gradient in vibrissa resonance across the vibrissa pad.

89 as a master clock for the synchronization of vibrissa, pad, and snout movements, as well as for the b

90 the primary somatosensory cortex of the rat vibrissa pathway, such integration across the vibrissa a

91 r motion in two processing stages of the rat vibrissa pathway.

92 Following vibrissa plucking, the levels of [125I]alpha-bungarotoxi

93 the known decoding of touch as a function of vibrissa position in the whisk cycle.

94 lectromyogram ( nabla EMG) as a surrogate of vibrissa position, and (ii) the field potential ( nabla

95 sa motor cortex report the absolute angle of vibrissa position.

96 eaths and are accompanied by an asymmetry in vibrissa positioning toward the same side of the face.

97 ation of sensory input as it progresses from vibrissa primary sensor (S1) to motor (M1) cortex.

98 rved that the local extracellular current in vibrissa primary sensory cortex contained oscillatory co

99 mata of multiple cubic millimeter regions of vibrissa primary sensory cortex in mouse.

100 nonlinear mixing of neuronal activity in the vibrissa primary sensory cortex of rat, a region that re

101 ion is preserved and transformed through the vibrissa processing pathway.

102 Displacement of one vibrissa produced a field of activity that extends over

103 ovides a precise tactile modality, including vibrissa-related 'barrel' columns in primary somatosenso

104 These results demonstrate that vibrissa-related central patterns are able to form in th

105 the pre-Botzinger complex (preBotC) and the vibrissa-related region of the intermediate reticular fo

106 in the whisk cycle, rather than angle of the vibrissa relative to the face.

107 ntly smaller-sized primary motor cortex (M1) vibrissa representation in the hemisphere contralateral

108 a result of unilateral lesions of the entire vibrissa representation of S-I barrel field cortex (BFC)

109 the cortical map, focuses the extent of the vibrissa representation relative to lower frequency stim

110 vibrissae, in agreement with the gradient in vibrissa resonance across the vibrissa pad.

111 Vibrissa resonance constitutes a potentially useful mech

112 We investigated the neural correlates of vibrissa resonance in trigeminal ganglion and primary so

113 y specificity, a further potential impact of vibrissa resonance is enhancement of sensitivity to near

114 First, vibrissa resonance significantly lowered the threshold f

115 vents, indicating that biomechanics, such as vibrissa resonance, shape signals most likely to drive n

116 short latency responses (median = 3.8 ms) in vibrissa-responsive LD neurons.

117 ts are thought to mediate the first stage of vibrissa scanning control via sensory feedback that prov

118 The representation of touch and vibrissa self-motion may in principle be encoded along s

119 onal signals that encode touch in the rodent vibrissa sensorimotor system.

120 ese neurons both receive primary inputs from vibrissa sensory afferent fibers and send monosynaptic c

121 he level and spatial extent of activation of vibrissa sensory cortex critically depend on behavioral

122 al loop consists of excitatory pathways from vibrissa sensory inputs to vibrissa motoneurons in the f

123 Rats lack precise vision, but their vibrissa sensory system provides a precise tactile modal

124 fication can increase the sensitivity of the vibrissa sensory system to an ecologically relevant rang

125 sduction during active sensing in the rodent vibrissa sensory system, a widely used model.

126 y in the relative frequency of dual forelimb-vibrissa sites that form the common border between these

127 yer 2/3 pyramidal neurons of the rat primary vibrissa (Sm1) cortex in vivo.

128 eurons within the thalamus and cortex of the vibrissa somatosensory system in the awake, freely movin

129 onset of vM1 optogenetic activation preceded vibrissa stimulation by 20 ms.

130 Increasing the intensity of vibrissa stimulation entailed more adaption in paralemni

131 ified the response of vS1 neurons to passive vibrissa stimulation in all cortical layers measured.

132 rated that the minimal amplitude of resonant vibrissa stimulation required to evoke responses in SI i

133 from LD neurons reveal that they respond to vibrissa stimulation with short latency (median = 7 ms)

134 by presenting low-amplitude, high-frequency vibrissa stimulation.

135 matotopy using a new omni-directional, multi-vibrissa stimulator.

136 arallels between frequency processing in the vibrissa system and the auditory system and have importa

137 We used the rat vibrissa system as a model for active sensing and determ

138 The rodent vibrissa system is a widely used experimental model of a

139 In the rodent vibrissa system, an ideal observer analysis of cortical

140 In the mouse vibrissa system, trigeminal brainstem circuits are thoug

141 st level of sensorimotor feedback in the rat vibrissa system.

142 se findings suggest strong parallels between vibrissa tactile processing and auditory encoding, in wh

143 ever, we lack a general dynamic model of the vibrissa that includes the effects of inertia, damping,

144 peri-threshold inputs (<or=80 microm at the vibrissa tip), we recorded NV and SI neurons during stim

145 equency, motions as small as 8 microm at the vibrissa tip, corresponding to angular deflections of le

146 ng, i.e., the rhythmic movement of the rat's vibrissas to acquire tactile information, occurs within

147 ides a mechanism for the rapid modulation of vibrissa touch during exploration of peri-personal space

148 sary to compute angular coordinates based on vibrissa touch.

149 to altered tactile experience by unilateral vibrissa trimming from birth (birth-trimmed group) or fo

150 Findings demonstrated that (1) vibrissa trimming from birth, but not when initiated in

151 ative cell implants repeatedly induced giant vibrissa-type follicles and fibres.

152 Local maxima for one vibrissa were seen to overlie the global maximum found f

153 sholds for eliciting movement of the trimmed vibrissa were significantly lower than normal; and (4) i

154 most clearly by transplanting ND-GFP-labeled vibrissa (whisker) hair follicles to unlabeled nude mice

155 ing perception, including stimulation of the vibrissa with moving complex natural stimuli such as san