ライフサイエンスコーパス: virtually

1 mbines CSF and OM RT-QuIC testing to provide virtually 100% diagnostic sensitivity and specificity in

2 n Tasmanian devils (Sarcophilus harrisii) is virtually 100% fatal.

3 e, computer-generated periodic gratings were virtually ablated via a computational process based on a

4 epubertal) female rats, wash-in of letrozole virtually abolished long-term potentiation (LTP), wherea

5 AMPK-alpha1 and AMPK-alpha2 deletion virtually abolished the hypoxic ventilatory response, an

6 her sites that limit 5'ppp-dsRNA sensing and virtually abrogate RIG-I activation.

7 Whereas transcripts of Clr-d and Clr-f are virtually absent from the spleen, Clr-g transcripts were

8 In stark contrast, the N(7)-H emission is virtually absent in AnsB, which supports a water-accessi

9 The calyceal processes were virtually absent in cones and displayed markedly reduced

10 ermum species at elevated concentrations but virtually absent in Leptospermum subtenue suggesting its

11 f a broad variety of lineages, whereas it is virtually absent in normal adult tissues.

12 thelial cell activation; this difference was virtually absent in patients more than 55 years old.

13 several rare deoxy amino l-sugars which are virtually absent in the human cells.

14 d T-bet(lo)Eomes(hi)(CXCR6+); the latter was virtually absent in the periphery.

15 cteristic, i.e. rather common in Finland but virtually absent or rare elsewhere in Europe.

16 In the absence of Mss116, Pet309 is virtually absent, and although mitoribosome loading onto

17 The Purkinje isoform Dp427p was virtually absent.

18 ation, indicative of extensive gene flow and virtually affecting all regions except East Africa, wher

19 otype appears frequently in the Amish, where virtually all affected individuals harbor homozygous fou

20 Virtually all agricultural communities worldwide are exp

21 Although virtually all AMLs with wild-type DNMT3A displayed CpG i

22 The majority of meningiomas and virtually all aneurysms not referred or referred but unt

23 overprinting from subsequent impact events, virtually all Apollo-era samples show evidence for (40)A

24 of nosocomial infections, and resistance to virtually all approved antibacterial agents is emerging

25 etween ENSO and southeast Asian SATs wherein virtually all April extremes occur during El Nino years.

26 ion of proteins with polyubiquitin regulates virtually all aspects of cell biology.

27 The complex pathophysiology of HF impacts virtually all aspects of normal cardiac function - from

28 al flood pulse, a phenomenon that influences virtually all aspects of river-floodplain ecosystem dyna

29 ogy, disorders of sodium handling may affect virtually all aspects of the homeostatic functions of th

30 As disorder severity increased, virtually all associations became stronger.

31 cules, i.e., molecular recognition, controls virtually all biological processes including the interac

32 ds and glycolipids are critical pathways for virtually all cell membranes.

33 perception that L. monocytogenes can infect virtually all cell types, neither naive nor inflammatory

34 P2Y receptors are expressed in virtually all cells and tissue types and mediate an asto

35 Exosomes are nanovesicles released by virtually all cells, which act as intercellular messenge

36 Double immunofluorescence demonstrated that virtually all ChAT-ir basal forebrain neurons were also

37 on in a wavelength range of 115-240nm, where virtually all chemical species absorb.

38 It infects virtually all children by the age of three years and the

39 cant BKI treatment effects were observed for virtually all clinical and parasitological scoring param

40 Although virtually all coronary artery disease associated single-

41 eaths occur in cholera-endemic settings, and virtually all deaths occur in developing countries.

42 ein of NSPCs, is constitutively expressed by virtually all ELCs before, during, and after regeneratio

43 In contrast, virtually all enteric glia express proteolipid protein 1

44 ase (MAPK) signaling cascades are present in virtually all eukaryotic cells.

45 of mobile elements present in the genomes of virtually all forms of life [1, 2].

46 onal migration are grounded in the view that virtually all functionally relevant microtubules (MTs) i

47 Virtually all guidelines recommend that patients should

48 In those tested, virtually all high-grade disease occurred in the 43.1% o

49 New NIH definitions classify virtually all human brain and behavioral research as cli

50 DNA repair gene defects are found in virtually all human glioblastomas, but the genetic evide

51 the measurable levels of BaP metabolites in virtually all human urine samples examined.

52 Calcium carries messages to virtually all important functions of cells.

53 ugh actions in the amygdala and accounts for virtually all interindividual variability in long-term f

54 s and allows retrospective investigations as virtually all ionized compounds are detected with a high

55 f naturally occurring scaffolds that targets virtually all known chemical functionalities and microen

56 e of the cell's fusion machinery and mediate virtually all known intracellular membrane fusion reacti

57 niphobic surfaces are extremely repellent to virtually all liquids.

58 ctive lysosomal acidification contributes to virtually all lysosomal storage disorders (LSDs) and to

59 RATIONALE: Virtually all mesenchymal stem cell (MSC) studies assume

60 application of a CSF1R inhibitor eliminated virtually all microglia from the visual system, whereas

61 Virtually all mitochondrial matrix proteins and a consid

62 All criteria sets accurately excluded virtually all nonclinical grief cases and accurately exc

63 amily, which are epigenetically repressed in virtually all normal cells.

64 LL cells of over 90% of patients, but not on virtually all normal postpartum tissues.

65 ce, and confocal imaging to demonstrate that virtually all NTS-->lPBN and lPBN-->CeA CGRP projections

66 ain of the S. aureus BirA results in loss of virtually all of its ligation activity.

67 However, virtually all of our quantitative knowledge about total

68 icient enzyme that catalyses the fixation of virtually all of the carbon found on Earth.

69 dopts context-specific dynamics that mediate virtually all of the events involved in the inner workin

70 Virtually all of the peptides/proteins examined herein c

71 detected after EPS removal, indicating that virtually all of the sulfhydryl sites are located on the

72 disordered regions within proteins result in virtually all of their primary sequence being exposed, a

73 ted hospitalizations were due to total heat, virtually all of which were from mild heat.

74 Because virtually all organisms compete with others in their soc

75 lay critical roles in chromosome dynamics in virtually all organisms, but how they function remains p

76 Unlike virtually all other receptors of medical interest, it ha

77 neuronal circuit mapping, and is applied to virtually all parts of the rodent nervous system, includ

78 r 3-methylglutaconic aciduria was present in virtually all patients (98%).

79 However, virtually all patients succumb to acquired EGFR tyrosine

80 on in adults, were conspicuously absent from virtually all pediatric cases.

81 ron is contacted by GABA-positive terminals, virtually all perisomatic terminals supplying it show GA

82 family of cell-surface receptors involved in virtually all physiological processes, are the major tar

83 Virtually all plastid (chloroplast) genomes are circular

84 ugh there was a drop in signal intensity for virtually all specimens under all storage/shipping condi

85 Another protein, eIF1A, is involved in virtually all steps, including subunit joining.

86 cells, with cognitive impairments evident in virtually all tauopathies.

87 In contrast, virtually all temporal patterning mechanisms discovered

88 tors, Hymenoptera play a fundamental role in virtually all terrestrial ecosystems and are of substant

89 Virtually all the intron-bound Rbfox is associated with

90 s transduced large numbers of hair cells and virtually all the supporting cells, along with close to

91 hanisms before initiating therapy extends to virtually all therapeutic considerations.

92 leotide exchange factors (Arf-GEFs) regulate virtually all traffic through the Golgi by activating Ar

93 ted in most major cardiovascular trials, and virtually all trials have excluded older patients with c

94 dopamine has a robust adhesion capability to virtually all types of surfaces.

95 diated signaling by the endothelium controls virtually all vascular functions.

96 ttention-control function, are necessary for virtually all volitional motor acts while its damage con

97 ocyte common antigen, and it is expressed in virtually all white cells and in hematopoietic stem cell

98 actors cooperate similarly in H3 eviction at virtually all yeast promoters.

99 an innate response essential for survival in virtually all-animal species.

100 bacteria" remains common in textbooks, it is virtually always stated without citation or argument.

101 can activate cell-intrinsic host defenses in virtually any cell type ranging from professional phagoc

102 ng has enabled the mutation and insertion of virtually any DNA sequence, particularly in cell culture

103 low therapeutic antibodies to be produced in virtually any expression system and still maintain effec

104 n the second step, allows the predictions of virtually any flat learning method to be enhanced.

105 tent the HPO terms predictions starting from virtually any flat learning method.

106 pores in the membrane and allows delivery of virtually any fluorescent probes, ranging from labeled I

107 n (HR) with engineered template DNA to alter virtually any gene and create mutant mice.

108 help to predict the perceptual qualities of virtually any molecule with high accuracy and also rever

109 sulting in oral and ocular dryness, although virtually any organ system can be affected.

110 calable, and rapid, and it can be applied to virtually any organism.

111 simplifying the creation of null alleles in virtually any organism.

112 sphate (ADP) enhances platelet activation by virtually any other stimulant to complete aggregation.

113 In principle, this approach accommodates virtually any peptide or expressed protein amenable to N

114 ecific incorporation of 5-hydroxyindole into virtually any protein.

115 d quantitative insights into the function of virtually any RBP.

116 cturing GMP compliant precision particles of virtually any size, shape, and composition, the PRINT te

117 path-amounts at distances up to 2000 m using virtually any solid surface as a reflector, whilst also

118 ll with the quality of the training data for virtually any stoichiometric inorganic crystalline mater

119 on various semiconducting small molecules on virtually any substrate by combining the advantages of a

120 rm and can be implemented directly on top of virtually any substrates.

121 e ease in E. coli and can be evolved to bind virtually any target.

122 zable and can be readily modified to monitor virtually any type of enzyme-catalyzed cleavage reaction

123 e possibility to study GABAergic function in virtually any vertebrate species.

124 y double-stranded RNA molecules derived from virtually any virus, and extremely specific, because it

125 TDA is virtually applicable to any solute with size ranging fro

126 of the molecular state of cells and tissues, virtually at every level of biological organization.

127 ling neutrophils and other immune cells were virtually blind to the pathogen's presence.

128 ltage characteristics of the transistor were virtually channel-length independent with an infinite ou

129 in the murine hippocampus that developed in virtually complete absence of vesicular glutamate releas

130 Data collected in <1 wk produced a virtually complete de novo assignment of the coat protei

131 e large sample size, prospective design, and virtually complete follow-up; however, histologic detail

132 3 of Drosophila mauritiana, which results in virtually complete hybrid male sterility when homozygous

133 with mutant transporter construct revealed a virtually complete loss of transport activity that was p

134 rated by portal angiography, which disclosed virtually complete portosystemic shunting in Fut2(-/-)(h

135 g nationwide population-based registers with virtually complete registration of all hospital contacts

136 et-s/GroEL aggregates and Het-s fibrils, but virtually completely eliminated in Het-s/GroEL fibrils,

137 strate that colloidal nanocrystals represent virtually defect-free systems, suffering from nonradiati

138 dispels the popular view that this region is virtually devoid of life.

139 spleens of Hdac3(F/-)Mb1-Cre(+/-) mice were virtually devoid of mature B cells, and B220(+)CD43(+) B

140 s and large pericentromeric regions that are virtually devoid of meiotic recombination.

141 ipient-derived T cells was low before KT and virtually did not change over time (0.0139% +/- 0.0039 a

142 tal and inferior-longitudinal fasciculi were virtually dissected using manual and automatic determini

143 g S1-M1 of the motor-sensory homunculus were virtually dissected using TrackVis, and diffusion proper

144 (N-CBZ) as a PfHsp90-selective inhibitor by virtually docking a large set of antimalarial compounds,

145 ation of domestic dogs and other animals has virtually eliminated human rabies in industrialized coun

146 ses, while sparing hair cells, in adult mice virtually eliminated the auditory brainstem response and

147 influenzae and Streptococcus pneumoniae has virtually eliminated the concern for bacterial infection

148 binding of ALO-D4 to the plasma membrane was virtually eliminated when cholesterol stores were deplet

149 Surprisingly, however, these effects were virtually eliminated when mussels were exposed to both h

150 h as anti-phosphatidylcholine B1a cells, are virtually eliminated.

151 thod based purely on light manipulation that virtually eliminates speckle noise originating from a sa

152 r sparse choices of explanatory features fit virtually equally well.

153 the functionality of the core language into virtually every biological domain (sequence and structur

154 entry serves critical cellular functions in virtually every cell type, and appropriate regulation of

155 Signalling by ubiquitination regulates virtually every cellular process in eukaryotes.

156 lations, and to map spatial distributions in virtually every CNS region and disease state.

157 Reconstructions indicate that virtually every DNA triplet was recognized by at least o

158 s ubiquitinate protein substrates to control virtually every eukaryotic process and are misregulated

159 he small modifier, ubiquitin (Ub), regulates virtually every known cellular process in eukaryotes.

160 ses in simple and elegant total syntheses in virtually every natural product class: terpenes, alkaloi

161 ematic functional organization is present in virtually every normal adult, including regions preferri

162 idespread, from the periplasm of bacteria to virtually every organelle in the human cell.

163 te back to the origins of life, are found in virtually every species and every cell, and play fundame

164 ive capsid protein, plays essential roles at virtually every step in the early phase of the viral lif

165 xecute a wide variety of regulatory roles at virtually every step of gene expression and translation.

166 onal complexity, as pathogens interfere with virtually every step of gene expression.

167 prosthetic group in proteins that reside in virtually every subcellular compartment performing diver

168 human body and contains molecules drawn from virtually every tissue, including the microbes and virus

169 blem with the concept of habit has been that virtually everyone has their own ideas of what is meant

170 The obtained nanoMIPs are virtually free of template and demonstrate high affinity

171 synthesize beta-sitostanyl oleate, yielding virtually full conversion of up to 80mM beta-sitostanol

172 jection, whereas wild-type controls achieved virtually full recovery.

173 luorescence anisotropy, observing tubulin in virtually fully monomeric and dimeric states.

174 xtracted among 162,000 preselected cases 102 virtually homoplasy-free, phylogenetically informative r

175 cloud radars' and Doppler lidar now provides virtually ideal instrumentation.

176 reveals that the degree of functional ITH is virtually identical between primary ccRCCs of the lowest

177 in the complex with either 4 or 18 displayed virtually identical binding modes and interactions, high

178 criticisms and find that all samples display virtually identical fabrics, argue that the modern setti

179 oportion of labeled neurons of each type was virtually identical in all cases, thus indicating that a

180 Quality-adjusted life-years were virtually identical in all the three treatment arms; hen

181 hough the selvamicin biosynthetic cluster is virtually identical in both bacterial producers, in one

182 wo most recent whole-genome duplications had virtually identical localization patterns, and that less

183 dent clonogenic growth potential compared to virtually identical populations that had been equally ex

184 dentical size allows the two spheres to have virtually identical refractive index sensitivity and sur

185 aratope we showed crystallographically to be virtually identical to that of 10E8, a potency on a pane

186 Outcomes were virtually identical to the current gold standards for co

187 cted than males (95% CI: 1.2-1.8), which was virtually identical to the relative risk of being at hom

188 ins, are sterile and display meiotic defects virtually identical to those observed in Cdk2 KO mice in

189 brachial, inguinal, and mesenteric LNs were virtually identical, and a substantial portion of identi

190 n (AR) and glucocorticoid (GR) receptors are virtually identical, yet these transcription factors sha

191 The tricuspid valve was virtually ignored for a long time in the past.

192 tency as 22R-HC (3) at LXRbeta, while it was virtually inactive at LXRalpha (EC50 = 14.51 muM).

193 stitutively, while proinflammatory cells are virtually inactive.

194 tulated final intermediate distal to Fea and virtually incapable of coordinating to it.

195 me range hue attention-filter selectivity is virtually independent of discriminabilty.

196 d organized collagen architectures that were virtually indistinguishable from those in age-matched un

197 uted polydiacetylenes (PDAs 1 and 2a-c) into virtually indistinguishable N = 8 armchair graphene nano

198 a varying malignancy potential ranging from virtually indolent tumors to rapidly progressing cancers

199 ise during parallel evolution, they might be virtually inevitable, as the combination of two such ste

200 erapies, relapse of multiple myeloma (MM) is virtually inevitable.

201 e activation and selective transformation of virtually inexhaustible or easy-to-generate chemicals li

202 he possibility of functionalization leads to virtually infinite MOF designs using generic modular met

203 , whereas the A329T mutation rendered CaMKK2 virtually insensitive to Ca(2+)-CaM stimulation.

204 ing compactional flattening, the specimen is virtually intact, comprising a fully articulated skeleto

205 iological materials, yet are lightweight and virtually invisible to the human immune system, and they

206 on and that of E. coli, making the signature virtually invisible.

207 ree energies indicate that all reactions are virtually irreversible.

208 nderstanding of diatom life cycle control is virtually lacking.

209 ncapsulation of cargo that can be contained, virtually leakage-free, over several months.

210 is an uncommon primary cause of death in HCM virtually limited to embolic stroke, supporting a low th

211 ly folded "hair trigger" device into which a virtually limitless number of microbial detection platfo

212 the plasma membrane of different cells with virtually molecular resolution by direct stochastic opti

213 comicelles and the individual segments were virtually monodisperse in length, which facilitated thei

214 Moreover, half of the patients carried virtually mutually exclusive mutations in other TCR-rela

215 BQSR had virtually negligible effect on INDEL calling and general

216 so became increasingly slower over time with virtually no 4-CINB reduction being observed after 18 da

217 tained therapeutic efficacy while exhibiting virtually no anaphylactic off-target effects.

218 us and Northern European components and have virtually no Asian influence.

219 The aHUS-linked CCP 19 mutant D1119G-CFH had virtually no CA on (self-like) sheep erythrocytes (ES) b

220 antioxidant present in many foods, bestowed virtually no CAA in HepG2 cells.

221 24% compaction, the most compact chains show virtually no change, and intermediate chains compress by

222 at our methodology is isoform-specific, with virtually no cross-hybridization, achieving limits of de

223 of TRF2 in post-mitotic immature neurons had virtually no detectable effect on circuit assembly, neur

224 rectly catalyzes recombination, it generates virtually no detectable indels or other stochastic DNA m

225 major pollutants, the program expansion had virtually no discernible effect on pollution levels.

226 and all but 18 nucleotides of the 5'-UTR had virtually no effect on the level of gene expression as l

227 ommendation is based on limited evidence and virtually no experimental data from the pediatric popula

228 There was virtually no increase in the quantity of customers makin

229 There is virtually no information assessing the insurability of f

230 terogeneous, with 40% of molecules requiring virtually no mechanical force to unfold (<10 piconewtons

231 lity assays revealed that OligoG CF-5/20 had virtually no membrane-perturbing effects.

232 this network is language-selective, showing virtually no modulation by nonlinguistic tasks.

233 nomic datasets [4] to SCG assemblies reveals virtually no overlap, suggesting that nuclear genomic di

234 g the genes involved in these two illnesses, virtually no progress had been made until the past decad

235 l tool in organic synthesis, there have been virtually no reports of processes that generate, much le

236 M17 wild-type levels in all tissues and show virtually no shedding of all tested ADAM17 substrates, t

237 in vehicle- or BRD3308-treated groups showed virtually no sign of immune cell infiltration, except mi

238 hen coevolved species shift out of sync, but virtually no studies have documented the effects of clim

239 , gold constitutes a notable exception, with virtually no well-characterized examples known to date.

240 adal-to-centennial climate changes are still virtually nonexistent despite substantial efforts to dev

241 receive diagnosis, and routine screening is virtually nonexistent in the USA.

242 he coordination chemistry of anionic gold is virtually nonexistent, and this unique oxidation state i

243 derivatives: diazabenzoindoles, which remain virtually nonfluorescent, despite having a similar, rigi

244 Conversely, we identified 8 virtually nonoverlapping patient subgroups, jointly comp

245 Hsp90 coimmunoprecipitated with beta2AR but virtually not with TPbeta, indicating that nascent GPCRs

246 ctenophore neural and muscular systems, and virtually nothing has been reported about their embryoge

247 Virtually nothing is known about the relevance of glycol

248 Virtually nothing is known about the role of these nonpr

249 s) have gained unprecedented popularity, but virtually nothing is known about their cardiovascular ri

250 linkage model reduced the linkage signal to virtually null.

251 , and (Hf0.2Zr0.2Ta0.2Cr0.2Ti0.2)B2, possess virtually one solid-solution boride phase of the hexagon

252 pedited treatment was that the procedure was virtually painless.

253 A virtually pathognomonic finding of NF1 is the plexiform

254 ge-dependent segmentation of the signal, and virtually precludes the possibility of making comparativ

255 Our method measures the impact of virtually resecting putative control regions on synchron

256 While circulating B cells are virtually restored to preinfection levels during the chr

257 ligands using a homology model of GPR171 to virtually screen a library of compounds.

258 of active compounds were mined and mapped to virtually screen potential analogs.

259 by principal component analysis matched the virtually screened data.

260 Participating groups virtually screened possible inhibitors from a library co

261 Optimized ligands from the database were virtually screened to obtain the most efficient and pote

262 n many enzyme active sites, yet has remained virtually silent as a probe in NMR spectroscopy.

263 t and violent offending were elevated across virtually the full spectrum of parental psychiatric dise

264 ntext, with a spatial resolution approaching virtually the molecular level.

265 Interestingly, virtually the same rigidification was seen upon exposing

266 are indispensable for SAR and necessary for virtually the whole transcriptional SAR response, a mode

267 n of complex polycyclic diketopiperazines in virtually their final forms, thus providing rapid and hi

268 In contrast, the N-I bond length is virtually unaffected by changes of the electron density.

269 inside RNA duplexes (<PhiF> = 0.22) that is virtually unaffected by the neighbouring bases (PhiF = 0

270 While dimers were virtually unbreakable, dimerization of the monomeric pop

271 ures left the association for lean body mass virtually unchanged (lowest HR: 1.33 [95% CI: 1.28 to 1.

272 ysis the effect size of the main outcome was virtually unchanged when the occurrence of AMs was assig

273 LTPA the level of these amino acids remained virtually unchanged.

274 hin the proto-lunar disk, which is as of yet virtually unconstrained.

275 chromothripsis, whereas this phenomenon was virtually undetectable in a control group of marker chro

276 addition, the p53 (Trp53) protein, which is virtually undetectable in early wild-type embryos, accum

277 , chemical space from 500 to 1000 Da remains virtually unexplored and represents a vast opportunity f

278 p), unlike many pi-building blocks, has been virtually unexplored in supramolecular constructs.

279 lar microbiomes are poorly characterized and virtually unexplored in wildlife species.

280 their impacts on variation in tolerance are virtually unexplored.

281 ional modes of plasmonic molecules have been virtually unexplored.

282 ons based on their electronic properties are virtually unexplored.

283 revealed that, whereas UV-induced damage is virtually uniform throughout the genome, repair is affec

284 CSR creates a virtually unique IgH locus in every B cell clone by intr

285 The standard genetic code (SGC) is virtually universal among extant life forms.

286 unoglobulin G, with the aim to demonstrate a virtually universal protein detection platform.

287 spite the importance of communication, it is virtually unknown how information is transferred in loca

288 nd potential function(s) of cementocytes are virtually unknown, and the question may be posed whether

289 factors controlling their distributions are virtually unknown.

290 l-known, the sublethal effects on fishes are virtually unknown.

291 HROOM3 in kidney development and function is virtually unknown.

292 NARE proteins reach their sites of action is virtually unknown.

293 ha-C(sp(3))-H containing amide substrates is virtually unlimited highlighting the potential value of

294 HPG Pore allows for virtually unlimited sequencing data scalability, thus gu

295 naive rabbit antibody library as a rich and virtually unlimited source of rabbit mAbs.

296 SiR provides a virtually unlimited temporal window for the study of net

297 he number of combinatorial TALE-VAS pairs is virtually unlimited, this platform provides an experimen

298 tands out among fluorescent bases due to its virtually unquenched fluorescence emission in duplex DNA

299 the kinetics in the presence of ligands are virtually unstudied.

300 ur analysis indicates that the S1' pocket is virtually vacated, thus free of any water molecules.