ライフサイエンスコーパス: virus RNA

1 e replication and transcription of influenza virus RNA.

2 SSPE were tested for the presence of measles virus RNA.

3 mized using a synthesized fragment of Dengue virus RNA.

4 ttle or no sequence similarity to the helper virus RNA.

5 o be involved in cyclization of yellow fever virus RNA.

6 does not stimulate the export of hepatitis B virus RNA.

7 en 1915 and 1919 were tested for influenza A virus RNA.

8 surface antigen (HBsAg) and hepatitis delta virus RNA.

9 d less efficiently than genomic Rous sarcoma virus RNA.

10 GM-CSF was +0.14 log human immunodeficiency virus RNA.

11 fficient packaging of avian leukosis-sarcoma virus RNA.

12 ng the 3' end of the minus strand of Sindbis virus RNA.

13 ive binding assay with tRNA and brome mosaic virus RNA.

14 emen specimen that tested positive for Ebola virus RNA.

15 imed with other PAMPs, including hepatitis C virus RNA.

16 h DI RNAs but not in synthesis of the helper virus RNAs.

17 e transcription and replication of influenza virus RNAs.

18 3'-untranslated region of pea enation mosaic virus RNA 2.

19 spectively; all had undetectable hepatitis C virus RNA 48 weeks after the end of therapy.

20 primary endpoint was absence of hepatitis C virus RNA 6 months posttreatment.

21 proteases p29 and p48 contributes to optimal virus RNA accumulation.

22 pse patients (undetectable serum hepatitis C virus RNA after 24 weeks of peginterferon-ribavirin and

23 t of which included detection of hepatitis D virus RNA among anti-hepatitis D virus seropositive part

24 teroviruses possess specialized functions in virus RNA amplification, virus invasion, and cell-to-cel

25 for ribosome shunting in cauliflower mosaic virus RNA and are well conserved in cIAP2 orthologs.

26 Plasma human immunodeficiency virus RNA and CD4 lymphocyte response to nucleoside reve

27 y reproducible quantification of hepatitis C virus RNA and displayed a nearly 600-fold dynamic range

28 infection, RIG-I-like receptors (RLRs) sense virus RNA and induce MAVS to form prion-like aggregates

29 L segment minigenome systems for analysis of virus RNA and protein features involved in replication.

30 the 3' untranslated region (UTR) of Sindbis virus RNA and relocalizes from the nucleus to the cytopl

31 l; after several years, both hepatitis delta virus RNA and serum HBsAg became undetectable.

32 nts in spleen necrosis virus and human foamy virus RNA and support the model that divergent retroviru

33 nt-independent expression of bovine leukemia virus RNA and supports the hypothesis that SNV RNA conta

34 f 519 donors who were positive for West Nile virus RNA and the removal of more than 1000 potentially

35 C infection, close monitoring of hepatitis C virus RNA and treatment of patients with persistent vire

36 mplexes (RNPs) formed by the hepatitis delta virus RNAs and protein, HDAg, perform critical roles in

37 n of a cellular protein binding to influenza virus RNAs and, importantly, suggest that influenza viru

38 ol dehydrogenase, satellite tobacco necrosis virus RNA, and alfalfa mosaic virus (AMV) 4, were used i

39 transferases, the level of serum hepatitis C virus RNA, and histologic necroinflammatory scores all d

40 NASBA) technique with which small amounts of virus RNA are amplified using a simple water bath.

41 Infection was assessed by measuring plasma virus RNA as well as T and B cell responses.

42 (undetectable [<125 IU/mL] serum hepatitis C virus RNA at 24-week follow-up).

43 efined as undetectable levels of hepatitis C virus RNA at 4 weeks) and were eligible to participate.

44 , reverse transcriptase PCR identified Ebola virus RNA at a higher level in CSF (cycle threshold valu

45 e (2 log10 reduction in level of hepatitis C virus RNA at week 12; n=466), and undetectable hepatitis

46 eek 12; n=466), and undetectable hepatitis C virus RNA at weeks 20 (n=320), 48 (end of treatment, n=2

47 replication, internal polyadenylation of B19 virus RNAs at (pA)p is favored in cells which are both p

48 microwave heating of a suspension of a model virus, RNA bacteriophage MS2, 13 chemical digestion prod

49 samples to screen blood donors for West Nile virus RNA began in July 2003.

50 For example, the human immunodeficiency virus RNA-binding protein Rev associates with the solubl

51 nt relationships with human immunodeficiency virus RNA blood levels.

52 These data show that heterologous virus RNAs (BSMV) can serve as primer donors for MStV mR

53 er unrelated IRES (from encephalomyocarditis virus RNA), but did not affect the 5'-end-dependent tran

54 he packaging signals for all eight influenza virus RNAs, but it lost the ability to independently rea

55 cipants' semen samples were tested for Ebola virus RNA by real-time RT-PCR and participants received

56 Duration of detection of Ebola virus RNA by real-time RT-PCR varies by individual and m

57 s from all five cases were positive for Zika virus RNA by RT-PCR, and sequence analyses showed highes

58 ) with a less than 2-log drop in hepatitis C virus RNA by week 4.

59 prevent the free reassortment of influenza A virus RNAs by rewiring their packaging signals.

60 tis C virus infection with serum hepatitis C virus RNA concentrations of at least 5 log10 IU/mL, crea

61 10.6-fold even at relatively low hepatitis C virus RNA concentrations.

62 Rous sarcoma virus RNA contains a negative regulator of splicing (NRS

63 ts of virus load >500 human immunodeficiency virus RNA copies/mL.

64 Virus RNA could be detected for up to 33 days in vaginal

65 ylcytidine (1) was designed as a hepatitis C virus RNA-dependent RNA polymerase (HCV RdRp) inhibitor.

66 subgenomic RNA synthesis by the brome mosaic virus RNA-dependent RNA polymerase (RdRp), provided that

67 For the brome mosaic virus RNA-dependent RNA polymerase (RdRp), we determined

68 rs (IC(50) = 0.08-3.8 microM) of hepatitis C virus RNA-dependent RNA polymerase (RdRp).

69 By using a purified dengue virus RNA-dependent RNA polymerase and a subgenomic 770-

70 Influenza virus RNA-dependent RNA polymerase consists of three vir

71 ion stability and poor activity of the avian virus RNA-dependent RNA polymerase in human cells.

72 More specifically, we show that the Nodamura virus RNA-dependent RNA polymerase interacts with the ou

73 The Sindbis virus RNA-dependent RNA polymerase nsP4 possesses an ami

74 would support the notion that the influenza virus RNA-dependent RNA polymerase undergoes a conformat

75 cessing of heterotypic segments by influenza virus RNA-dependent RNA polymerase, an inhibitory effect

76 Influenza A virus RNA-dependent RNA polymerase, purified from virion

77 erstood but is suggested to target influenza virus RNA-dependent RNA polymerase.

78 hildren had recombinant vesicular stomatitis virus RNA detectable in saliva.

79 Hepatitis A virus RNA detected in clinical specimens was sequenced t

80 Median duration of Ebola virus RNA detection was 158 days after onset (73-181; ma

81 The duration of mumps virus RNA detection was studied during a mumps outbreak

82 assuming an eclipse of 7 d from infection to virus RNA detection.

83 the 5' end of type 1 human immunodeficiency virus RNA dimerize spontaneously in vitro in a reaction

84 Picorna-like insect virus RNAs direct an unorthodox form of translation init

85 py (AFM) was used to detect HCV (hepatitis C virus) RNA directly and to quantitatively analyse it wit

86 oat globulin, and satellite tobacco necrosis virus RNA displayed the strongest dependence on eIF4B.

87 ts with a >2-log(10) decrease in hepatitis C virus RNA during prior PEG-IFN/RBV therapy: 11% (4/38) i

88 K cells in the presence of bafilomycin A(1), virus RNA enters the cell and is translated, but replica

89 ctions as a positive effector of hepatitis B virus RNA export.

90 , by use of in situ hybridization, to detect virus RNA expression before and after in vitro T cell ac

91 of short, terminally labeled probes to Ebola virus RNA followed by click assembly and analysis of the

92 The two ribozymes found in hepatitis delta virus RNA form related but non-identical secondary struc

93 mprove amplification-free detection of Ebola virus RNA from blood.

94 Intracellular dengue virus RNA from cells infected with transcript-derived vi

95 -mediated initiation on encephalomyocarditis virus RNA from purified components and used primer exten

96 at 50% and 90% of male survivors clear Ebola virus RNA from seminal fluid at 115 days (90% prediction

97 s data showed a mean clearance rate of Ebola virus RNA from seminal fluid of -0.58 log units per mont

98 INTERPRETATION: Time to clearance of Ebola virus RNA from seminal fluid varies greatly between indi

99 . have claimed to have recovered influenza A virus RNA from Siberian lake ice, postulating that ice m

100 bjects who achieved undetectable hepatitis C virus RNA from weeks 4 and 12, known as extended rapid v

101 scription and replication of the influenza A virus RNA genome are mediated by the viral RNA polymeras

102 n 5A (NS5A) encoded by the human hepatitis C virus RNA genome is shown here to induce the activation

103 volved in the packaging of Rift Valley fever virus RNA genome segments, L, M, and S.

104 he U5-IR loop of the feline immunodeficiency virus RNA genome suggests a novel intermolecular interac

105 its effects on gene expression by the killer virus RNA genome.

106 -based sensors for the detection of the Zika virus RNA genome.

107 region, which is responsible for capping the virus RNA genome.

108 anscription and replication of the influenza virus RNA genome.IMPORTANCE Influenza A viruses are a ma

109 low mosaic (TYMV) and kennedya yellow mosaic virus RNAs had activities in all three properties simila

110 Ebola virus RNA has been noted in the following body fluids da

111 The unusual structure of hepatitis delta virus RNA has previously been shown to enhance its stabi

112 Vaccinia virus RNA helicase (NPH-II) catalyzes nucleoside triphos

113 tions (ts10, ts18, and ts39) of the vaccinia virus RNA helicase nucleoside triphosphate phosphohydrol

114 The data suggest that hepatitis C virus RNA helicase, and therefore viral replication, cou

115 The hepatitis C virus RNA helicase, NS3, is an important model system fo

116 ferase) RNA or naturally capped brome mosaic virus RNA, however, was not affected by the presence of

117 shedding, as defined by detection of measles virus RNA in > or =1 specimen obtained 30-61 days after

118 ring the 3 weeks following diagnosis yielded virus RNA in 93% of tests.

119 ed that the number of men positive for Ebola virus RNA in affected countries would decrease from abou

120 r methods allow reliable detection of rabies-virus RNA in biological fluids or tissue before death.

121 d transaminitis and had prolonged detectable virus RNA in blood and semen, suggesting that the possib

122 We monitored Ebola virus RNA in CSF and plasma, and sequenced the viral gen

123 osensor allows the rapid detection of Dengue virus RNA in only 15 min.

124 compared with the ability to detect rubella virus RNA in oral fluids by reverse transcription-PCR (R

125 in reaction assay was used to detect measles virus RNA in peripheral blood mononuclear cells, urine,

126 Detectable human immunodeficiency virus RNA in peripheral blood was associated with lower

127 had been discharged with undetectable Ebola virus RNA in peripheral blood.

128 er concentrations of simian immunodeficiency virus RNA in plasma, and those engaging in affiliation h

129 data showed the long-term presence of Ebola virus RNA in semen and declining persistence with increa

130 r time, we found that concentration of Ebola virus RNA in semen during recovery is remarkably higher

131 We report the presence of Ebola virus RNA in semen in a cohort of survivors of EVD in Si

132 itability in detecting the presence of Ebola virus RNA in semen.

133 posttransplant, with detectable hepatitis C virus RNA in serum and features of hepatitis C on liver

134 ty, Calif.) for the detection of hepatitis C virus RNA in serum and plasma.

135 inely detected in deer mice which maintained virus RNA in the blood and lungs.

136 technique was used to detect La Crosse (LAC) virus RNA in the central nervous system (CNS) tissues of

137 This study modeled the presence of Ebola virus RNA in the semen of male Ebola survivors participa

138 h the use of consensus primers detected Zika virus RNA in the serum of the patients but no dengue vir

139 In addition, the inhibition of brome mosaic virus RNA in vitro translation in wheat germ lysates by

140 (EUA) and are routinely used to detect Ebola virus RNA in whole blood and plasma specimens at the Lib

141 To study the encapsidation of Sindbis virus RNAs in infected cells, we designed a new assay th

142 We probed the structure of murine leukemia virus RNA inside virus particles using SHAPE, a high-thr

143 h NH(4)Cl did not prevent the penetration of virus RNA into the cell cytoplasm or translation of the

144 lpha) production is triggered when influenza virus RNA is detected by appropriate pattern recognition

145 Accumulation of unspliced Rous sarcoma virus RNA is facilitated in part by a negative cis eleme

146 Sequencing of the RT gene from plasma virus RNA isolated at peak viremia confirmed that both o

147 Barley yellow dwarf virus RNA, lacking a 5' cap and a 3' poly(A) tail, conta

148 A dramatic reduction in hepatitis C virus RNA level was observed after 2 days of treatment w

149 nts was evaluated and effects on hepatitis C virus RNA level, quasispecies evolution, and liver histo

150 Ebola virus RNA levels (virus load) in PBMC specimens were fou

151 Hepatitis E virus RNA levels also remained detectable in the serum a

152 patients had significantly lower hepatitis C virus RNA levels and more favorable changes in hepatic h

153 Patients with baseline hepatitis C virus-RNA levels (bHCV-RNA)>6 log IU/mL or cirrhosis hav

154 e quantitation of the human immunodeficiency virus RNA load in blood.

155 modelling to describe the dynamics of Ebola virus RNA load in seminal fluid, including clearance par

156 D4(+) T lymphocytes in uninfected AGMs, milk virus RNA load in SIV-infected AGMs was comparable to th

157 protein cleavage is sufficient for mediating virus RNA maturation.

158 11 of the A complementation group of Sindbis virus RNA-negative mutants.

159 0 donations that were positive for West Nile virus RNA, of which 362 (67 percent) were IgM-antibody-n

160 s disease was confirmed by a finding of Zika virus RNA or a specific neutralizing antibody response t

161 The crystal structure of an alfalfa mosaic virus RNA-peptide complex reveals that conserved AUGC re

162 a from 4 subjects had human immunodeficiency virus RNA pol T215Y/F mutant and 4 had codon 215 wild ty

163 nserved amino acids in bovine viral diarrhea virus RNA polymerase (BVDV RdRp) and RdRps from related

164 sm of initiation of replication by influenza virus RNA polymerase and establish whether initiation of

165 An interaction between the influenza A virus RNA polymerase and the C-terminal domain (CTD) of

166 e the principle of the assay using influenza virus RNA polymerase and yeast PAP as examples.

167 hate (T-705-RTP), is recognized by influenza virus RNA polymerase as a substrate competing with GTP,

168 alyzed the elongation properties of vaccinia virus RNA polymerase during a single round of transcript

169 and that the error rate of the yellow fever virus RNA polymerase employed by the chimeras for genome

170 tion of the vRNA promoter with the influenza virus RNA polymerase heterotrimeric complex is likely to

171 The PB2 subunit of the influenza virus RNA polymerase is a major determinant of viral pat

172 The PB2 subunit of the influenza virus RNA polymerase is a major virulence determinant of

173 The vaccinia virus RNA polymerase is a multi-subunit enzyme that cont

174 ing that the PB2 627 domain of the influenza virus RNA polymerase is not involved in core catalytic f

175 of N-end rule substrates such as the Sindbis virus RNA polymerase nsP4 (bearing N-terminal Tyr) and t

176 vidence that the H4L subunit of the vaccinia virus RNA polymerase plays a direct role in transcriptio

177 We have previously shown that Sindbis virus RNA polymerase requires an N-terminal aromatic ami

178 Vaccinia virus RNA polymerase terminates transcription downstream

179 Vaccinia virus RNA polymerase terminates transcription in respons

180 Vaccinia virus RNA polymerase terminates transcription in respons

181 Thus, influenza virus RNA polymerase uses different initiation strategie

182 The YLD virus RNA polymerase was able to express genes regulated

183 ates the remarkable flexibility of influenza virus RNA polymerase, and aids our understanding of the

184 d partially purified recombinant influenza A virus RNA polymerase, in the absence of influenza virus

185 says using a surrogate respiratory syncytial virus RNA polymerase.

186 uclear-cytoplasmic large double-stranded DNA virus RNA polymerases, and plant plastid RNA polymerases

187 e infected with SIN/beclin had fewer Sindbis virus RNA-positive cells, fewer apoptotic cells, and low

188 gulatory T cells reduced the amount of Seoul virus RNA present in the lungs and the proportion of ani

189 g interaction with and regulation of rubella virus RNA processing.

190 in the initiation but not the maintenance of virus RNA propagation and also contributes to the regula

191 double mutant of the 26 nt potato leaf roll virus RNA pseudoknot.

192 <10,000 copies/mL of human immunodeficiency virus RNA (range, <500-1250).

193 a plasmid DNA vaccine incorporating Sindbis virus RNA replicase functions (pSINCP) and expressing an

194 rans-acting proteins, L and NP, required for virus RNA replication and gene expression were exchangea

195 trans-acting viral factors required for both virus RNA replication and gene transcription, requires t

196 e host factors is revealing basic aspects of virus RNA replication and helping to define the normal f

197 membrane association of positive-strand RNA virus RNA replication complexes is implicated in their f

198 Using a system to study Sindbis virus RNA replication in Drosophila melanogaster, we fou

199 cal, efficient synthesis of 1, a hepatitis C virus RNA replication inhibitor, is described.

200 Positive-strand RNA virus RNA replication is invariably membrane associated

201 PF-429242 did not affect virus RNA replication or budding but had a modest effect

202 nt insights into the early events in Sindbis virus RNA replication suggest a requirement for either t

203 e genome and encodes the enzymes involved in virus RNA replication).

204 HCV-induced dsRNA foci, the likely sites of virus RNA replication, and propose that HCV genome synth

205 inhibition was due not to interference with virus RNA replication, gene expression, or budding but r

206 67K mutations did not affect GPC processing, virus RNA replication, or gene expression.

207 Here, we show that BeAn virus RNA replication, translation, polyprotein processi

208 he OTU protease activity was dispensable for virus RNA replication.

209 bis virus genome are significant for Sindbis virus RNA replication.

210 cell lines transfected with a Semliki Forest virus RNA replicon encoding a single viral structural pr

211 uman papillomavirus type 16 E7, in a Sindbis virus RNA replicon vector.

212 These included DNA encoding Sindbis virus RNA replicons (pSINCP), cationic poly(lactide-co-g

213 Using engineered Sindbis virus RNA replicons expressing puromycin acetyltransfera

214 solation and characterization of hepatitis C virus RNA replicons resistant to a novel ketoamide inhib

215 accine platform consisting of Semliki Forest virus RNA replicons that express the vesicular stomatiti

216 Amplification of replication-competent alpha-virus RNAs (replicons) can be initiated by RNA or DNA tr

217 e that amplification of turnip yellow mosaic virus RNA requires aminoacylation, but that neither the

218 ly that frameshifting on Barley yellow dwarf virus RNA requires viral sequence located four kilobases

219 t the colinear mRNA derived from influenza C virus RNA segment 6 serves as the mRNA for CM2.

220 ear mRNA transcript derived from influenza C virus RNA segment 6.

221 The coding region of influenza A virus RNA segment 7 from the 1918 pandemic virus, consis

222 The virus RNA segment S, M, and L untranslated regions were

223 RNA species are derived from the influenza C virus RNA segment six, (i) a colinear transcript contain

224 c packaging signals for individual influenza virus RNA segments are located in the 5' and 3' noncodin

225 us, including modern-looking avian influenza virus RNA sequences from an archival goose specimen coll

226 ses studied for the presence of Epstein-Barr virus RNA showed scattered positivity in 2-7% of lymphoi

227 CSF Ebola virus RNA slowly declined and was undetectable following

228 inhibit the synthesis of all three influenza virus RNA species, block Crm1-dependent nuclear export,

229 formed during the interaction of a West Nile virus RNA stem loop structure with the human T cell-rest

230 ranscription of specific portions of measles virus RNA, such as the nucleocapsid gene, appears able t

231 + T215rev showed full human immunodeficiency virus RNA suppression while receiving a TDF- or tenofovi

232 ing activity but retained their functions in virus RNA synthesis and assembly of infectious particles

233 rk advances our understanding of influenza A virus RNA synthesis and identifies the initiation platfo

234 rk advances our understanding of Influenza A virus RNA synthesis and identifies the initiation platfo

235 iral infectious cycle in switching influenza virus RNA synthesis from transcription mode to replicati

236 nant purified hnRNP C proteins can stimulate virus RNA synthesis in vitro and that depletion of hnRNP

237 Influenza A virus RNA synthesis is catalyzed by the viral polymerase

238 e production of infectious virus and blocked virus RNA synthesis when added prior to infection.

239 signaling is required for maximal influenza virus RNA synthesis, viral ribonucleoprotein (vRNP) nucl

240 athway can differentially regulate influenza virus RNA synthesis, which may also offer some new persp

241 specifically impede intracellular influenza virus RNA synthesis.

242 NA, transcribed from the double-stranded CTF virus RNA template by reverse transcriptase PCR.

243 tant to gain wider knowledge about influenza virus RNA to create new strategies for drugs that will i

244 has shown a differential effect on influenza virus RNA transcription and replication.

245 inhibitors specifically diminished influenza virus RNA transcription from the cRNA promoter but not f

246 e the inhibition but also activate influenza virus RNA transcription from the cRNA promoter.

247 We propose that N(pro) is involved with virus RNA translation in the cytoplasm for virus particl

248 Chlorella virus RNA triphosphatase (cvRtp1) is the smallest member

249 reviously shown to be essential for vaccinia virus RNA triphosphatase activity inactivated the tripho

250 oposal that protozoan, fungal, and Chlorella virus RNA triphosphatases belong to a single family of m

251 In some eukaryotic viruses, RNA upstream of the coding region forms an inte

252 p every 3-6 weeks, which we tested for Ebola virus RNA using quantitative real-time RT-PCR.

253 that ICP27 also mediates the export of some virus RNAs via a Crm1-dependent pathway and present evid

254 Replication of plus-strand RNA viruses [(+)RNA viruses] is performed by viral replicase

255 All well-characterized positive-strand RNA viruses[(+)RNA viruses] induce the formation of host mem

256 ment-specific packaging signals of influenza virus RNAs (vRNAs) are located in the 5' and 3' noncodin

257 Mumps virus RNA was characterized directly from cerebrospinal

258 Influenza virus RNA was detected as well or better after 6 months

259 Ebola virus RNA was detected in 86 semen specimens from 19 (73

260 Hepatitis C virus RNA was detected in Gammagard, and the risk of tra

261 More virus RNA was detected in the brain and spinal cord of I

262 Ebola virus RNA was detected in the semen of all 7 men with a

263 c biliary atresia in the 10 patients in whom virus RNA was detected.

264 However, the Delta p48 mutant virus RNA was rescued when p48 was provided in trans.

265 Levels of virus RNA were reduced in HLA-DR transgenic mice compare

266 vels of infectious virus, virus antigen, and virus RNA were similar in both groups.

267 Eggplant mosaic virus RNA, which has a differently constructed acceptor

268 alylated 3'-fragment of turnip yellow mosaic virus RNA, which has a pseudoknotted amino acid acceptor

269 of sustained clearance of serum hepatitis C virus RNA, which is influenced, in turn, by the patient'

270 Erysimum latent virus RNA, which lacks an identifiable anticodon domain,

271 ancing the hybridization of the target Ebola virus RNA with capture probes bound to the beads.

272 F3), if a >2-log(10) decrease in hepatitis C virus RNA with previous PEG-IFN/RBV treatment was achiev

273 45-base synthetic fragment of Harvey sarcoma virus RNA with recombinant or synthetic HIV-1 NC protein

274 od donations were being tested for West Nile virus RNA with the use of investigational nucleic acid a