ライフサイエンスコーパス: virus-derived

1 (LS strain) fused to the cauliflower mosaic virus-derived 35S promoter.

2 tified 32 independent incursions of an avian virus-derived A allele into mammals, whereas 6 introduct

3 be detected from tissues 14 d postinfection, virus-derived Ag continues to drive a CD4(+) T cell resp

4 tion to determine the duration and impact of virus-derived Ag presentation.

5 cted DC maintain the ability to present both virus-derived and exogenous Ags, but that they actively

6 Assays measuring both Epstein-Barr virus-derived and human IL-10 yielded higher values than

7 When a similar test using virus-derived antigen was performed, a loss of both spec

8 gle day of antigenic stimulation even though virus-derived antigens (Ags) are still presented by DCs

9 The kinetics of presentation of influenza virus-derived antigens (Ags), resulting in CD4 T cell ef

10 nd proliferation in response to bacteria and virus-derived antigens.

11 Mutation within virus-derived CD8 T-cell epitopes can effectively abroga

12 uantum dots, carrying a controlled number of virus-derived (cognate) and other (noncognate) pMHC-I co

13 s transposon reverse transcriptases, produce virus-derived complementary DNAs (vDNA).

14 ll nuclei, usually through the deployment of virus-derived components.

15 ve previously shown that vaccines expressing virus-derived cytotoxic-T-lymphocyte (CTL) epitopes as s

16 n, many prokaryotes incorporate fragments of virus-derived DNA into loci called clustered regularly i

17 the ancestral parvovirus genome into a large virus-derived DNA transposon of the Polinton (polintovir

18 The Sindbis virus-derived DNA vectors described here increase the ut

19 thway that responds through the detection of virus-derived double-stranded RNA to suppress virus repl

20 P19 homodimers sequester 21-nt virus-derived duplex siRNAs, and it is thought that this

21 nstituted of viruses that infect host cells, virus-derived elements in our chromosomes, and viruses t

22 Rel is a chimeric protein that has 11 helper virus-derived Envelope (Env) amino acids (aa) at its N t

23 t three mutant residues in the eleven helper virus-derived Envelope (Env) amino acids (aa) at the N-t

24 plication, orchestrated by integrase (IN), a virus-derived enzyme.

25 Using a panel of 38 defined influenza A virus-derived epitopes recognized by C57BL/6 mouse CD8(+

26 as yet inadequate for identifying influenza virus-derived epitopes.

27 f persistent exposure to structurally stable virus-derived epitopes.

28 of HIV-, hepatitis B virus-, and hepatitis C virus-derived epitopes.

29 mulation with a lymphocytic choriomeningitis virus-derived escape mutant as demonstrated by the susta

30 d humans were infected by an HIV-1 precursor virus derived from a contaminated poliovaccine.

31 Two were infected with a wild-type virus derived from a full-length infectious clone (A12-I

32 d for efficacy against a multidrug-resistant virus derived from a highly experienced patient expressi

33 f influenza A/WSN/33 (H1N1), a mouse-adapted virus derived from a human influenza strain first isolat

34 f HIV-associated immunopathogenesis, using a virus derived from a human pathogen, we identified a sig

35 Virus derived from a second clone, p19/wenv16, caused so

36 cular evolution of a feline immunodeficiency virus derived from a wild cougar, Puma concolor, during

37 no long-term viral evolution, implying that virus derived from activated latent cells must dominate.

38 Virus derived from both clones caused persistent infecti

39 Virus derived from clone p19/wenv17 caused severe debili

40 ith BALB/c-adapted A/New Caledonia influenza virus derived from four consecutive lung pool passages.

41 Here, we describe a chimeric virus derived from GB virus B (GBV-B), an unclassified h

42 A virus derived from HSV-1(U(L)17-stop) but containing a r

43 isrupt the U5-PBS-tRNAMet interaction of the virus derived from HXB2(Met-AC).

44 Virus derived from IN-minus provirus is noninfectious.

45 in pig cell lines productively infected with virus derived from NIH miniature pig and Yucatan pig PBM

46 Virus derived from pHXB2(His-AC-GAC) with M184V RT had s

47 d provirus from a cell culture infected with virus derived from pHXB2(His-AC-TGT) revealed a G-to-A c

48 tRNA(His) to initiate reverse transcription [virus derived from pHXB2(His-AC-TGT)] revealed five addi

49 Virus derived from pMRE16ic replicated with the same eff

50 SHIV-KB9, a molecularly cloned virus derived from SHIV-89.6P, also caused CD4+ T-cell d

51 otypic analyses showed no difference between virus derived from subjects after TCN-032 treatment and

52 virus isolates and rechallenged them with a virus derived from the 2009 H1N1 A/CA/04/09 virus, named

53 Virus derived from the BAC clone had a wild-type phenoty

54 While virus derived from the clone containing the M47 mutation

55 Using the Wyeth strain of vaccinia virus derived from the Dryvax vaccine, we generated a re

56 Plaque-purified virus derived from the infectious construct replicated e

57 Plaque-purified virus derived from the infectious construct replicated e

58 An infectious molecular clone of virus derived from the isolate from macaque PGm (PGm5.3)

59 Using a recombinant virus derived from the JFH1 strain, we confirmed that pl

60 inated target cells infected with autologous virus derived from the latent reservoir, both in vitro a

61 A at 1,000 times the lethal dose of vaccinia virus derived from the licensed Dryvax vaccine seed.

62 Several studies have used virus derived from the molecular clone SFV4.

63 Nevertheless, comparison of the virus derived from the mutant (ps51) and wild-type (ps55

64 Following long-term infection with virus derived from the pathogenic GL8 molecular clone of

65 Virus derived from this clone differs from nonneuroinvas

66 A virus derived from this mutant but bearing a restored U(

67 ld-type S.A.AR86 infectious clone, ps55, and virus derived from this mutant clone, ps51, was signific

68 The virus derived from this yeast-assembled genome, KOS(YA),

69 Virus derived from transcripts containing mutations in t

70 iants that arose after drug selection, using virus derived from two different HIV proviral clones, NL

71 Animals were inoculated with a plaque-cloned virus derived from VR-2332, the North American PRRS viru

72 rain of the 2009 new pandemic H1N1 influenza virus, derived from the A/California/07/2009 isolate and

73 components, prompting hypotheses that these viruses derived from a fourth domain of cellular life.

74 Viruses derived from a Merlin-BAC derivative in which RL

75 ), and infection of a single pony (678) with viruses derived from a mixture of five of these molecula

76 reen of primary viral isolates revealed that viruses derived from asymptomatic, infected people had l

77 parent virus at 32 degrees C. ts+ revertant viruses derived from both mutants have also reverted in

78 These results show that viruses derived from C499 are more pathogenic for chimpa

79 s with HCV pseudoparticles and cell-cultured viruses derived from different heterologous 1a, 1b, 2a,

80 uate the infectivity and cellular tropism of viruses derived from different hosts.

81 sting each primer-probe pair against various viruses derived from laboratory virus stocks, as well as

82 arboviruses more efficiently infect DCs than viruses derived from mammalian cells.

83 To assess the cellular source of infectious viruses derived from MDM, virus-containing media from in

84 Viruses derived from Merlin-BAC in fibroblasts had mutat

85 ral strains, including neutralization escape viruses derived from other nAbs; however, no single nAb

86 p6 domain of Gag are frequently observed in viruses derived from patients on protease inhibitor (PI)

87 vealed that by day 15 of culture, the PBS of viruses derived from pHXB2(His) and pHXB2(His-T psi C) r

88 In contrast, viruses derived from pHXB2(His-AC) maintained a PBS comp

89 erably more nucleotide substitutions than in viruses derived from pHXB2(His-AC-GAC) containing the M1

90 s obtained after transfection, we found that viruses derived from pHXB2(His-AC-GAC) with the wildtype

91 ) with wild-type RT and M184V RT compared to viruses derived from pHXB2(His-AC-GAC).

92 tion of reverse transcription was delayed in viruses derived from pHXB2(His-AC-TGT) with wild-type RT

93 proviral genomes revealed that the PBSs from viruses derived from pHXB2(Met) and pHXB2(AC-Met) revert

94 In contrast, the viruses derived from pHXB2(Met-AC-Met) stably maintained

95 , novel mutant viruses were identified among viruses derived from pHXB2(Met-C-Met) at day 35 postcocu

96 Viruses derived from pMRE16icDeltaE200-Y229 and pMRE16ic

97 We characterized the replication fitness of viruses derived from pNL4-3 containing P236L or K103N in

98 f the growth phenotypes of additional mutant viruses derived from RNAs containing DEN2-WN chimeric 3'

99 Recombinant viruses derived from S648 and HSV-1(delta U(L)15ExII) an

100 Here we use wild-type and Vif-deficient viruses derived from the CD4(+) T cells of multiple dono

101 Sequencing of the viruses derived from the D17 cell lines revealed second-

102 We used NS1 truncated mutant influenza viruses derived from the human isolate influenza A/TX/91

103 e with a randomized DIS, infected cells with viruses derived from the library, and monitored the emer

104 Furthermore, viruses derived from the MLV chimera with SNV CA could s

105 ase-driven replication capacity than that of viruses derived from the mothers (P < 0.0001 by a paired

106 were inoculated with two recombinant hybrid viruses derived from the parent viruses SIVmac239, a lym

107 oliomyelitis have been shown to be caused by viruses derived from the Sabin vaccine strains.

108 Viruses derived from the transfection of these proviral

109 Using a set of viruses derived from these chimeras by exchanging portio

110 re detected in the growth characteristics of viruses derived from these clones as compared to the ori

111 In assays using a panel of reassortant viruses derived from these strains, the difference in AT

112 Viruses derived from these transfected cells were infect

113 Propagation of viruses derived from TR-BAC, TB40-BAC4, and FIX-BAC in e

114 ptation, we selected mutant receptor-adapted viruses derived from two P1/Mahoney variants, one which

115 ted subjects or seronegative plasma to which viruses derived from wild-type and mutant infectious mol

116 susceptible to infection with avian leukosis virus-derived gene vectors.

117 ronger cellular immunity in rodents than did virus-derived gene.

118 ell death in response to the accumulation of virus-derived glycosphingolipids upon infection of natur

119 uced a predominant Th1 response, and the PR8 virus-derived HA110-120 peptides induced a mixed Th1/Th2

120 complexed with a H-2Kk-restricted influenza virus-derived hemagglutinin peptide (Ha255-262) but does

121 nce an alternatively added HA (for influenza virus-derived hemagglutinin) epitope tag caused similar

122 Hepatic overexpression of the virus-derived human ET-1 mRNA was accompanied by a 13-fo

123 ructural motifs within Op-IAP, an efficient, virus-derived IAP.

124 and with VSV-mediated virotherapy, and that virus-derived IFN-beta would add further safety to the V

125 In contrast, expression of CrmA, a cowpox virus-derived inhibitor of the Ced-2-like proteases ICE

126 iated herpesvirus are autocrine dependent on virus-derived interleukin-6 (IL-6), but not on cellular

127 ant genes and there are no reports of animal virus derived IRES activity in plant cells.

128 oto-oncogene from which the Abelson leukemia virus derived its Gag-v-Abl oncogene, recent results hav

129 sites, located between two Moloney leukemia virus-derived LTR, into which genes of interest may be i

130 Thus far, detection of virus-derived miRNAs has been largely limited to DNA vir

131 well known that these pathogens make use of virus-derived multitasking proteins, as well as dedicate

132 SHIV(MD14) carrying simian immunodeficiency virus-derived nef established significantly higher virus

133 Correspondingly, virus-derived noncoding and antisense transcripts may sh

134 hus, neither the A nor the B allele of avian virus-derived NS segments necessarily attenuates virus r

135 responses to infection showed that the avian virus-derived NS segments provoked lower levels of expre

136 o test this, a number of clade A and B avian virus-derived NS segments were introduced into human H1N

137 ty of infected cells or cells triggered with virus-derived nucleic acids to produce type I interferon

138 Mammalian cells recognize virus-derived nucleic acids using a defined set of intra

139 n (IFN-I) and other cytokines in response to virus-derived nucleic acids.

140 ly related to the avidity of the TCR for the virus-derived peptide (p) + major histocompatibility com

141 te algorithms identified 101 influenza A PR8 virus-derived peptides as potential epitopes for CD8+ T

142 Six virus-derived peptides from five different viral protein

143 se by inhibiting the cell surface display of virus-derived peptides on MHC class I molecules.

144 ple, of a large collection of ~30,000 dengue virus-derived peptides only 0.3% were predicted to bind

145 virus-infected cells through recognition of virus-derived peptides presented at the cell surface by

146 inal proline residues was observed in Hendra virus-derived peptides presented by Ptal-N*01:01 on the

147 CD8(+) T cells that recognize virus-derived peptides presented on MHC class I are vita

148 :01, and elucidated the binding capacity for virus-derived peptides.

149 elicit cytotoxic CD8(+) T cells specific for virus-derived peptides.

150 We also report detection of virus-derived PIWI-interacting RNAs (piRNAs) in Drosophi

151 Using a Tobacco rattle virus-derived plasmid for in planta transient expression

152 and 8 CFU of Escherichia coli carrying Ebola virus-derived plasmids.

153 nt DLAV vaccine (TV005) with pools of dengue virus-derived predicted major histocompatibility complex

154 Peptides were fused to the hepatitis B virus-derived PreS domain as recombinant fusion proteins

155 I mainly by interfering with the function of virus-derived primary siRNAs.

156 lerated primary B cell response to influenza virus-derived protein, evidenced by high anti-nucleoprot

157 To study the role of the virus-derived proteins on the development of these elect

158 r untreated primary cultures with viruses or virus-derived replicons that lacked the structural prote

159 n of replication-incompetent murine leukemia virus-derived retroviral vectors.

160 the 3' U3 region of Moloney murine leukemia virus-derived retroviral vectors.

161 fense against viral infection by recognizing virus-derived RNAs and are localized to intracellular me

162 replication-competent, noncytopathic Sindbis virus-derived RNAs.

163 ve-strand RNA viruses requires production of virus-derived secondary small interfering RNAs (siRNAs)

164 gh mice infected with viruses with the avian virus-derived segment 8s had reduced weight loss compare

165 nal plasmid vector and from a Semliki Forest virus derived, self-replicating vector.

166 ting genetic subtypes were included, as were viruses derived shortly after transmission and during th

167 report here the generation of an X31 (H3N2) virus-derived single-cycle infectious influenza virus, X

168 s was associated with a much higher level of virus-derived siRNA accumulation compared to plants infe

169 In plants, virus-derived siRNAs (viRNAs) can target and silence cel

170 antiviral RNAi pathway and the generation of virus-derived siRNAs (viRNAs).

171 ivirus-induced gene silencing by quantifying virus-derived siRNAs and by evaluating their distributio

172 mature human somatic cells produce abundant virus-derived siRNAs co-immunoprecipitated with AGOs in

173 Next, we evaluated the distribution of virus-derived siRNAs on the respective virus genome at t

174 NV) does not result in the production of any virus-derived siRNAs or viral miRNAs.

175 S is likely initiated by a process guided by virus-derived small (s) RNAs that are 21/22-nt in length

176 Virus-derived small interfering RNA (siRNA) is a primary

177 of polymorphisms and recombination, and the virus-derived small interfering RNA (vsiRNA) sequences i

178 In addition, AGO1 recruits virus-derived small interfering RNAs (siRNAs) in vivo, s

179 ntiviral RNA interference (RNAi) directed by virus-derived small interfering RNAs (siRNAs) represents

180 eins to suppress RNAi as their hosts produce virus-derived small interfering RNAs (siRNAs) that direc

181 Diverse eukaryotic hosts produce virus-derived small interfering RNAs (siRNAs) to direct

182 ies and mosquitoes induces the production of virus-derived small interfering RNAs (siRNAs) to specifi

183 is antiviral immunity involves production of virus-derived small interfering RNAs (viRNAs) and result

184 llenberg virus resulted in the production of virus-derived small interfering RNAs (viRNAs) of 21 nucl

185 We identified virus-derived small interfering RNAs (viRNAs), 21 nt in

186 s in infected cells showed the production of virus-derived small interfering RNAs (viRNAs), which are

187 nd RNA viruses can trigger the biogenesis of virus-derived small interfering RNAs (vsiRNAs), we show

188 verse eukaryotic organisms, Dicer-processed, virus-derived small interfering RNAs direct antiviral im

189 ible for antiviral defense and generation of virus-derived small interfering RNAs, in DI RNA producti

190 The roles of virus-derived small RNAs (vsRNAs) have been studied in p

191 We now report the accumulation of virus-derived small RNAs (vsRNAs) in hypovirus CHV1-EP71

192 he generation by Dicer-like (DCL) enzymes of virus-derived small RNAs of 21 to 24 nucleotides (nt) th

193 ped a sequence-independent strategy based on virus-derived small RNAs produced by the host response,

194 By sequencing virus-derived small RNAs, we show that the viruses repre

195 Here we describe examples of influenza A virus-derived small viral RNAs (svRNAs).

196 results in the RNAi-dependent production of virus-derived, small-interfering RNAs (viRNAs), which in

197 to miRNAs, we also identified novel forms of virus-derived smRNAs, revealing greater complexity withi

198 Mice were immunized with a pool of virus-derived T-cell epitopes.

199 f HIV-1 RT and on wild-type HIV-1 and mutant viruses derived thereof, Ile100 and Cys181, in cell cult

200 tly delivering sgRNAs using a Tobacco mosaic virus-derived vector (TRBO) designed with 5' and 3' sgRN

201 the lentivirus vector and a murine leukemia virus-derived vector in thymocytes.

202 Using the Rous sarcoma virus-derived vector RCAS, we previously showed that mut

203 lla luciferase) expression from an influenza-virus-derived vector.

204 Gag was expressed by using a Semliki Forest virus-derived vector: under these conditions, the Semlik