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1 bed by a four-subunit RNA polymerase that is virus encoded.
4 the ORF1 polyprotein was generated, and the virus-encoded 3C-like (3CL) proteinase (Pro) mediated cl
13 ion between corresponding family clusters of virus-encoded ANK and Skp1 proteins from three chlorovir
14 e triggered at mitochondria and modulated by virus-encoded anti-apoptotic B cell leukemia (BCL)2-like
16 pase-8, cytokine response modifier A (cowpox virus-encoded antiapoptotic protein), or DN Fas-associat
18 e efficiency difference between cellular and virus-encoded antigens is based on whether the antigen i
19 red thirty-six of the proteins were vaccinia virus-encoded ( approximately 64% of the known vaccinia
20 view the discovery of viral master circuits: virus-encoded autoregulatory gene networks that autonomo
22 wed that CBP interacts with the Epstein-Barr virus-encoded basic region zipper (b-zip) protein, Zta,
24 Virulence in animal models depends on the virus-encoded bifunctional Z-DNA/double-stranded RNA (ds
25 (GILGFVFTL) and the dissimilar Epstein-Barr virus-encoded BMLF1(280-288) epitope (GLCTLVAML), that,
26 ression of immune subversion proteins of the virus encoded by genes belonging to the US gene family.
32 with diversity-generating retroelements and virus-encoded Clustered Regularly Interspaced Short Pali
37 relevant to understanding the potential of a virus-encoded cytokine-like molecule, HHV8 vIL6, to indu
38 intramolecular disulfide bond formed by the virus-encoded cytoplasmic redox pathway, and is incorpor
39 the formation of which required the vaccinia virus-encoded cytoplasmic redox pathway, and was localiz
40 iated proteins localized to the periphery of virus-encoded cytoplasmic structures, termed virus facto
41 n presented to the immune system as vaccinia virus-encoded cytosolic or endoplasmic reticulum (ER)-ta
43 progress is leading to the identification of virus-encoded determinants responsible for altering fung
46 ous amounts of methylated nucleotides due to virus-encoded DNA methyltransferases (MTases); about 25%
47 inding protein (OBP), one of seven essential virus-encoded DNA replication proteins, to specific sequ
48 evaded by transcription of highly structured virus-encoded dsRNA inhibitors that bind to and inactiva
49 circumvent PKR function by transcription of virus-encoded dsRNA inhibitors that bind to and inactiva
50 tethering, mediated by Brd4 interaction with virus-encoded E2 protein, facilitates viral genome segre
51 ulated by cellular transcription factors and virus-encoded E2 proteins that act as sequence-specific
52 understanding of the mechanisms by which the virus-encoded E6 oncoproteins contribute to cell transfo
53 hile their direct autoregulatory activity on virus-encoded early gene products is completely preserve
60 somal DNA of a host cell and is one of three virus-encoded enzymes that are required for replication.
63 analysis indicated that the mutation in the virus-encoded external scaffolding protein was primarily
66 ssociated proteins around the peripheries of virus-encoded factories, interrupting the normal formati
69 both plant and invertebrate hosts requires a virus-encoded function to block the RNA silencing antivi
70 eptibility to cucumber mosaic virus when the virus-encoded function to suppress RNAi was disrupted.
72 es is transcribed, including one of the four virus-encoded G protein-coupled receptors (GPCRs), US28.
75 d cells that express a broad spectrum of the virus-encoded genes (type III latency; EBV+/III), EBV-po
76 c analysis reveals that 65% of the predicted virus-encoded genes are expressed during lytic infection
77 ce, host-cell-derived tissue factor (TF) and virus-encoded glycoprotein C (gC) can stimulate protease
78 s initiated by the interaction of the Friend virus-encoded glycoprotein gp55 with the erythropoietin
81 ion of CTL specific for recombinant vaccinia virus-encoded gp160, indicating its ability to bind endo
82 s expressing only US28 but not the remaining virus-encoded GPCRs is phenotypically similar to that of
84 acterization of the aptamers showed that the virus-encoded hemagglutinin, a protein expressed on the
88 s and vaccinia virus specifically, utilize a virus-encoded host range factor(s), such as a member of
89 ropism at the cellular level is regulated by virus-encoded host range proteins acting downstream of v
91 hermore, the absence of analogous degrons in virus-encoded IAPs explains their relative stability and
94 t has resulted in a delicate balance between virus-encoded immune evasion mechanisms and host antivir
96 sing this assay, we have identified an Ebola virus-encoded inhibitor of the type I IFN response, the
98 This enzymatic process is catalyzed by the virus-encoded integrase protein, which is conserved amon
100 ces correlate with the sequence/structure of virus-encoded integrases, supporting the idea that integ
103 activated KSHV early lytic genes, including virus-encoded interleukin 6 and polyadenylated nuclear R
104 or implicated in transformation and latency, virus-encoded interleukin-8, a CXC chemokine, and pp38 a
109 he latter, (iii) neither viral DNA nor other virus-encoded late proteins are required for the interac
111 virus (EBV) nuclear antigen 3C (EBNA3C) is a virus-encoded latent antigen essential for primary B-cel
113 al tumor nasopharyngeal carcinoma (NPC), the virus-encoded latent membrane protein LMP2A is consisten
114 nd transmembrane domains of the Epstein-Barr virus-encoded latent membrane protein-1 (LMP1) fused to
115 ng infected cells to differentiate using the virus-encoded LMP1 and LMP2a proteins, which act as func
116 ed that several nonenveloped viruses utilize virus-encoded lytic peptides for host membrane disruptio
117 ty between the HLA-A2-restricted influenza A virus-encoded M1(58-66) epitope (GILGFVFTL) and the diss
118 We propose that the NEC functions as minimal virus-encoded membrane-budding machinery during nuclear
119 e identification and characterization of two virus-encoded methyltransferases (MTases) involved in RN
122 genes in the animal kingdom, although animal virus-encoded microRNAs (miRNAs) are known to guide effi
127 ese findings imply that some host targets of virus-encoded miRNAs are likely to be of little selectiv
130 s are continuing but the recent discovery of virus-encoded miRNAs indicates that viruses also use thi
132 miRNAs and there is evidence to suggest that virus-encoded miRNAs target specific host genes and path
139 itiation factor eIF4E and VP39 (the vaccinia virus-encoded mRNA cap-specific 2'-O-methyltransferase),
143 pect to virus production and accumulation of virus-encoded mRNAs measured by real-time PCR when K-Rta
144 nological, based on T-cell responses against virus-encoded neoantigen(s) expressed in tumor cells.
145 mbinant fusion protein comprised of a cowpox virus encoded NKG2D binding protein (OMCP) and a mutated
146 ied, little is known about the structures of virus-encoded non-structural proteins that are essential
151 revealed the presence of a substrate for the virus-encoded NS2B-NS3 protease at the carboxy-terminal
152 s observed as discrete foci, associated with virus-encoded NS5A and core proteins and identical in mo
154 oliferation and the EBV latency Epstein-Barr virus-encoded nuclear antigen (EBNA)2 transcriptional tr
155 -alanine repeat domain (GAr) of Epstein-Barr virus-encoded nuclear antigen 1 (EBNA1) prevents major h
157 ive sense RNA that are encapsidated with the virus-encoded nucleocapsid (N) protein to form a ribonuc
158 t C6 in the 2'-deoxynucleoside series showed virus-encoded nucleoside kinase-sensitive anti-VZV activ
159 RB) family of tumor suppressor proteins, and virus-encoded oncogenes disrupt the RB-E2F repressor com
160 nd the carcinogenic mechanism of hepatitis B virus-encoded oncoprotein HBx, we explored the function
161 factor receptor family, and the Epstein-Barr virus-encoded oncoprotein latent membrane protein 1 (LMP
163 nducing kinase and the human T-cell leukemia virus-encoded oncoprotein Tax or be constitutively turne
164 rus 40 (SV40) large tumor antigen (Tag) is a virus-encoded oncoprotein which is the target of a stron
170 MERS-CoV replication depends in part on a virus-encoded papain-like protease (PL(pro)) that cleave
171 Deletion of 88% [Phe(25) to Pro(243)] of the virus-encoded papain-like protease, p29, in the context
173 onformation of gamma, a membrane-disrupting, virus-encoded peptide usually sequestered inside the cap
178 ermediate transcription factor, comprised of virus-encoded polypeptides A8 and A23, was previously id
179 provide direct evidence that AC4 is a unique virus-encoded posttranscriptional gene-silencing suppres
180 ved after CVB3 infection at G175 and G436 by virus-encoded protease 2A(pro), independent of caspase a
183 e mechanism of STAT signaling evasion, but a virus-encoded protein called V plays a central role in t
184 mplexes (RNPs) formed by these RNAs with the virus-encoded protein hepatitis delta antigen (HDAg) per
186 assemble in the host cell membrane from the virus-encoded protein PVAP and open at the end of the in
187 nsactivator of transcription (Tat), an early virus-encoded protein required for the efficient transcr
188 to the ability to phosphorylate H5, the only virus-encoded protein shown to be a B1 substrate in vivo
192 hondria-localized inhibitor of apoptosis), a virus-encoded protein with a unique, albeit poorly under
193 otic function of NSP4 is balanced by another virus-encoded protein, NSP1, which is implicated in PI3K
195 s, and there is increasing evidence that the virus-encoded protein, Tax, plays a primary role in vira
196 icornaviral RNA replication utilizes a small virus-encoded protein, termed 3B or VPg, as a primer to
197 ient cleavage of the capsid precursor by the virus-encoded proteinase is a critical determinant in th
199 oteins that are proteolytically processed by virus-encoded proteinases to produce mature replicase pr
206 Combined, these analyses revealed 148 unique virus-encoded proteins associated with the virion (about
212 udies have uncovered new mechanisms by which virus-encoded proteins inhibit Ub and Ub-like (Ubl) modi
214 duce a restrictive defense response but that virus-encoded proteins may be involved in differential i
215 polyproteins presumed to incorporate all the virus-encoded proteins necessary for viral RNA synthesis
216 that procapsids can be formed in vitro from virus-encoded proteins only without any requirement for
217 e focusing on agents that block Epstein-Barr virus-encoded proteins or induce lytic cycle agents.
218 man cytomegalovirus (HCMV), contains over 70 virus-encoded proteins that are incorporated during a nu
219 of herpesvirus late genes depends on several virus-encoded proteins whose function is not completely
220 in WDV minichromosomes and/or interaction of virus-encoded proteins with specific host factors are co
223 HCMV gB is also one of the most immunogenic virus-encoded proteins, and a significant fraction of vi
225 ng live-cell imaging of viral RNA (vRNA) and virus-encoded proteins, we show that the TGB proteins ha
234 eparations, >88% of the theoretical vaccinia virus-encoded proteome was detected with high confidence
238 V DNA replication, the TRs are nicked by the virus-encoded Rep proteins at the terminal resolution si
239 lving interactions between the viral genome, virus-encoded replication factors, and host factors.
240 luding a requirement of two PCV Oris and the virus-encoded replication initiator Rep protein, suggest
241 auses G(1) cell cycle arrest mediated by the virus-encoded replication-associated protein (RAP) (or K
242 A(1) was found to block the expression of a virus-encoded reporter gene in both infection and transf
243 Holliday junctions, which are cleaved by the virus-encoded resolvase enzyme to form unit-length genom
246 se is a multiprotein complex, containing the virus-encoded RNA polymerase L and P proteins, and two c
248 provide evidence for a mechanism by which a virus-encoded RNA silencing suppressor represses the tra
251 trate that deregulated expression of Us11, a virus-encoded RNA-binding, ribosome-associated protein i
252 (HCV) nonstructural protein 5B (NS5B) is the virus-encoded RNA-dependent RNA polymerase (RdRp) essent
256 n the nucleocapsid must be accessible by the virus-encoded RNA-dependent RNA polymerase in order to s
257 equence similarity with RuvC, the absence of virus-encoded RuvA and RuvB to interact with, and the di
258 ted by differential substrate specificity of virus-encoded serine palmitoyltransferase, a key enzyme
259 ted herpesvirus (KSHV) lytic infection, many virus-encoded signaling molecules (e.g., viral G protein
263 plication, we recently demonstrated that the virus-encoded single-stranded (ss) DNA-binding protein (
264 d with a multisubunit complex containing the virus-encoded single-stranded DNA-binding protein ICP8.
267 ovirus-associated (VA) RNAs and Epstein-Barr virus-encoded small RNAs (EBERs) with respect to RNA seq
268 gest a potential role for either cellular or virus-encoded SSB protein in improving the processivity
269 ing to a better understanding of the role of virus-encoded structural proteins not only in KSHV-relat
270 hat depends upon neither mouse mammary tumor virus-encoded superantigens nor MHC class II expression.
271 en1 mutant plants and in plants expressing a virus-encoded suppressor of RNA silencing (P1/HC-Pro), w
273 uses host enzymes, with the exception of the virus-encoded T-antigen (T-ag), to replicate its genome.
274 of how early protein interactions involving virus-encoded tegument proteins are critical for virus a
279 tes by Epstein-Barr virus (EBV) requires the virus-encoded transactivator EBNA2 and the products of b
280 V gene 62, is the major immediate-early (IE) virus-encoded transactivator of viral gene transcription
281 (HTLV-1) gene expression is mediated by the virus-encoded transactivator protein Tax and three imper
283 coding changes in the core components of the virus-encoded transcription and replication apparatus.
286 irus-transposon vector that stably maintains virus-encoded transgenes in vivo through integration int
288 sform vertebrate cells through the action of virus-encoded tumor antigens that interfere with normal
290 SV40) large tumor antigen (Tag) represents a virus-encoded tumor-specific antigen expressed in many t
292 erization of an inhibitor active against the virus-encoded type-1 topoisomerase, an enzyme likely to
293 ntrol of PABP1, Paip2, and EDD1 required the virus-encoded UL38 mTORC1 activator and resulted in augm
294 observations together with the presence of a virus-encoded uracil DNA glycosylase indicates that HSV-
297 ne responses likely drove the evolution of a virus-encoded virulence factor that regulates complement
298 n of translation initiation factors with the virus-encoded VPg protein covalently linked to the 5' en
299 ate transcription factor (VITF)-1 and -3 are virus-encoded, whereas VITF-2 was partially purified fro
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