ライフサイエンスコーパス: visual pigment

1 be used for tracking spectral shifts in any visual pigment.

2 nd accessory member of which contain the LWS visual pigment.

3 does not limit the regeneration of bleached visual pigment.

4 the chromophore for the regeneration of the visual pigment.

5 n combines with another 11cRAL to form a new visual pigment.

6 pigments, rods, rod opsin expression, or rod visual pigment.

7 form a normal complement of light-sensitive visual pigment.

8 he Schiff base chromophore and produce an UV visual pigment.

9 cells arises from thermal activation of the visual pigment.

10 ovide to cones for the regeneration of their visual pigment.

11 totransduction and efficient regeneration of visual pigment.

12 ent to bleach a considerable fraction of the visual pigment.

13 is impossible because they all use the same visual pigment.

14 1 (Rh1) may serve as the counterion of this visual pigment.

15 ects the spontaneous decay of photoactivated visual pigment.

16 sensitive pigments in addition to the main L visual pigment.

17 f the six UV receptor types contain the same visual pigment.

18 placed with 11-cis retinal to regenerate the visual pigment.

19 inal in the cone inner segment to regenerate visual pigment.

20 ecycling of visual chromophore for the opsin visual pigments.

21 omophore and how they affect the function of visual pigments.

22 the retinal in the red- and green-sensitive visual pigments.

23 Vision begins with photoisomerization of visual pigments.

24 -retinal as the light-sensing chromophore in visual pigments.

25 study pathogenic rhodopsin mutants and other visual pigments.

26 o produce 11-cis-retinal, the chromophore of visual pigments.

27 el chromophore studies, the vast majority of visual pigments.

28 ling a novel mechanism of spectral tuning of visual pigments.

29 T-PCR was used to investigate mRNAs encoding visual pigments.

30 s that regulate the expression of particular visual pigments.

31 in the photoactivation of both rod and cone visual pigments.

32 e consistent with the observed repertoire of visual pigments.

33 anism of its ultrafast photoisomerization in visual pigments.

34 oplasmic protein, analogous to higher animal visual pigments.

35 identified as wavelength regulating sites in visual pigments.

36 ferences between invertebrate and vertebrate visual pigments.

37 ecessary for the formation of photosensitive visual pigments.

38 that have modified the absorption spectra of visual pigments.

39 -cis-retinol during regeneration of the cone visual pigments.

40 the corresponding photosensitive molecules, visual pigments.

41 ties typical of batho intermediates of other visual pigments.

42 and rapid visual transduction in vertebrate visual pigments.

43 diversification among these and other insect visual pigments.

44 omparison of signals in cones with different visual pigments.

45 odopsin, which evolved from less stable cone visual pigments.

46 e opsin gene family encoding light-absorbing visual pigments.

47 ckly evaluate the thermal activation rate of visual pigments.

48 , this set of receptors is based on only two visual pigments.

49 tum efficiencies comparable to those seen in visual pigments.

50 s340-linked frame as proposed by Warshel for visual pigments.

51 light occurs by two-photon isomerization of visual pigments.

52 al tuning of monkey red- and green-sensitive visual pigments.

53 roducing the shortest and longest wavelength visual pigments.

54 nd behaviour, but unusual specialisations of visual pigments [1], mitochondrial tRNAs [2], and postcr

55 The chromophore of the visual pigments, 11-cis retinal, is derived from vitamin

56 he efficient recycling of the chromophore of visual pigments, 11-cis-retinal, through the retinoid vi

57 For visual pigments, a covalent bond between the ligand (11-

58 tinal sensitivity is enhanced by red-shifted visual pigments, a longwave reflecting tapetum and, uniq

59 fected both single-cone opsin expression and visual pigment absorbance in the rainbow trout alevin bu

60 orbance in the rainbow trout alevin but only visual pigment absorbance in the smolt and in zebrafish.

61 not induce any opsin switches or change the visual pigment absorbance of photoreceptors.

62 ing previously published wavelengths of peak visual pigment absorbance, we compared how four alternat

63 ecular mechanisms that regulate invertebrate visual pigment absorption are poorly understood.

64 ecular mechanisms that regulate invertebrate visual pigment absorption are poorly understood.

65 vation to the counterion switch mechanism of visual pigment activation.

66 consistent with a faster regeneration of the visual pigment after bleaching.

67 pand rhodopsin's role in vision from being a visual pigment and major outer segment building block to

68 is vital for maintaining both the amount of visual pigment and photoreceptor health in light-exposed

69 d to carry almost 27 kcal/mol energy in both visual pigments and absorb (lambda(max)) at 528 nm in bo

70 for the unexpected blue shift of 5-demethyl visual pigments and could explain why 5-demethyl artific

71 he melanopsins are only distantly related to visual pigments and in terms of their biochemistry share

72 etes, which leads to deficient generation of visual pigments and neural retinal dysfunction in early

73 scribe the localization of cone types, their visual pigments and opsin expression.

74 d real-time PCR to analyze the expression of visual pigments and other photoreceptor-specific genes d

75 Using two UV-sensitive visual pigments and the UV-filtering properties of four

76 uced charge displacements in plasma membrane visual pigment, and used it to measure pigment bleaching

77 Biochemical experiments with rhodopsin, cone visual pigments, and a chromophore model compound 11-cis

78 in, the protein component of light sensitive visual pigments, and other phototransduction cascade sig

79 11-cis-Retinal is bound to opsins, forming visual pigments, and when the resulting visual chromopho

80 prior to the chromophore rejoining with the visual pigment apo-proteins.

81 f visual chromophore and regeneration of the visual pigment are critical for the continuous function

82 Visual pigments are G-protein-coupled receptors that pro

83 f not only genetic control systems, but also visual pigments are near 70%.

84 Vertebrate and invertebrate visual pigments are similar in amino acid sequence, stru

85 n retinal release rates between rod and cone visual pigments arise, not from inherent differences in

86 tion as the counterion in other invertebrate visual pigments as well.

87 n by microspectrophotometry to have two cone visual pigments at 530 and 400 nm.

88 mino acids near the Schiff base in different visual pigments: at site 292 (A292S, A292Y, and A292T) i

89 that a substantial fraction of nonactivated visual pigments becomes phosphorylated through this mech

90 covery of a-wave response following moderate visual pigment bleach is delayed in KI/KI mice.

91 all-trans retinol is formed after visual pigment bleaching through the reduction of all-tr

92 relocate the highly conserved Lys296 in the visual pigment bovine rhodopsin.

93 press a vertebrate rhodopsin as a functional visual pigment, but the expression does not activate the

94 11 has a measurable role in regenerating the visual pigment by complementing RDH5 as an 11-cis-RDH in

95 Activation of the visual pigment by light in rod and cone photoreceptors i

96 tors, light photoactivates rhodopsin or cone visual pigments by converting 11-cis-retinal to all-tran

97 assessed key residues in rhodopsin and cone visual pigments by mutation analysis and identified two

98 Cone short-wave (SWS1) visual pigments can be divided into two categories that

99 basis of the spectral tuning of contemporary visual pigments can be illuminated only by mutagenesis a

100 Visual pigments can be thermally activated via isomeriza

101 The photosensitive molecules, visual pigments, can be synthesized in vitro and their a

102 eye possesses a mechanism to regenerate the visual pigment chromophore 11-cis retinal in the dark en

103 mice (Rpe65-/-) are unable to synthesize the visual pigment chromophore 11-cis retinal; however, if t

104 Production of 11-cis-retinal, the visual pigment chromophore, was suppressed with a potent

105 As a result, the signaling properties of visual pigments, consisting of a protein, opsin, and a c

106 The chromophore of all known visual pigments consists of 11-cis-retinal (derived from

107 Naturally occurring visual pigments contain only PSB11 and 3,4-dehydro-PSB11

108 For example, rod and cone visual pigments couple to distinct variants of the heter

109 Enhancing visual pigment deactivation does not appear to protect a

110 er segments, mislocalization and decrease in visual pigments, decreased expression of retinoic acid-r

111 These findings demonstrate that visual pigment dephosphorylation regulates the dark adap

112 r 20 degrees C photoexcitation of artificial visual pigments derived either from 5-demethylretinal or

113 f lauryl maltoside suspensions of artificial visual pigments derived from 9-cis isomers of 5-ethylret

114 Our work provides convincing evidence for visual pigment dimerization in vivo under physiological

115 s down to >1000 m, and both the rod and cone visual pigments display short wave shifts as depth incre

116 tebrate vision is mediated by five groups of visual pigments, each absorbing a specific wavelength of

117 ustaceans and insects, whereas red-sensitive visual pigments evolved later as a result of convergent

118 n, whereas activin, BMP2, and BMP4 inhibited visual pigment expression and outer segment formation, a

119 R) and Northern blot analysis to investigate visual pigment expression at the mRNA level.

120 est that multiple regulatory systems control visual pigment expression during differentiation of chic

121 Efficient regeneration of visual pigment following its destruction by light is cri

122 Rapid regeneration of the visual pigment following its photoactivation is critical

123 The visual pigment for this photoreceptor may be melanopsin,

124 Mice express S and M opsins that form visual pigments for the detection of light and visual si

125 Lepidopteran green- and red-sensitive visual pigments form a monophyletic clade, which lends s

126 Mutations in rhodopsin, the visual pigment found in rod cells, account for a large f

127 ngth sensitive 2 (SWS2) family of vertebrate visual pigments from the retina of the Japanese common n

128 primates, trichromacy was made possible by a visual pigment gene duplication.

129 anism for the evolution of trichromacy after visual pigment gene duplication.

130 he mechanisms that control the cell-specific visual pigment gene transcription, the Xenopus rhodopsin

131 a photon of light captured by a molecule of visual pigment generates an electrical response in a pho

132 e present partial cDNA sequences of ostracod visual pigment genes (opsins).

133 Rod visual pigment genes have been studied in a wide range o

134 trol region (LCR) of the human red and green visual pigment genes is critical for the formation of fu

135 lectively induced or down-regulated specific visual pigment genes, but many cognate rod- or cone-spec

136 onfirms the absence of other classes of cone visual pigment genes.

137 The absorption spectra of visual pigments have a broad bell shape, with the peak b

138 mouse ultraviolet (UV) and bovine blue cone visual pigments have absorption maxima of 358 and 438 nm

139 nstituted with 11-cis-retinal, the resulting visual pigments have wavelengths of maximal absorption (

140 ese sharks revealed the presence of a single visual pigment in each species.

141 g the day when a substantial fraction of the visual pigment in our photoreceptor cells is bleached.

142 A corresponding reduction of visual pigment in the shortened outer segments may lead

143 ters but lack 11-cis-retinoids and rhodopsin visual pigment in their retinas.

144 The spectral absorbance of the visual pigment in these eyes shifts towards longer wavel

145 unique opportunity to study the evolution of visual pigments in a group of closely related species ex

146 sight into molecular evolution of vertebrate visual pigments in achieving low discrete dark noise and

147 dium (M, green) and long (L, red) wavelength visual pigments in all fish species examined.

148 cling of 11-cis retinal, the chromophore for visual pigments in both rod and cone photoreceptors.

149 istent with the faster regeneration rates of visual pigments in cone-dominant retinas.

150 ive physiological studies that red-sensitive visual pigments in insects have paralogous origins.

151 All known visual pigments in Neuralia (Cnidaria, Ctenophora, and B

152 The visual pigments in photoreceptors are bound to 11-cis-re

153 fish, and killifish and on the absorbance of visual pigments in rainbow trout and zebrafish.

154 molecular switch for activating cone and rod visual pigments in response to light stimulation, but al

155 naling pathway that links photoactivation of visual pigments in retinal photoreceptor cells to a chan

156 generates 11-cis-retinal, the chromophore of visual pigments in rod and cone photoreceptor cells need

157 Vision relies on photoactivation of visual pigments in rod and cone photoreceptor cells of t

158 al to 11-cis-retinal for the regeneration of visual pigments in rod and cone photoreceptor cells.

159 d vision requires continuous regeneration of visual pigments in rod and cone photoreceptors by the 11

160 ential for the generation of light-sensitive visual pigments in the vertebrate retina.

161 l-phospholipids.It is currently thought that visual pigments in vertebrate photoreceptors are regener

162 ester to 11-cis retinal, the chromophore for visual pigments in vertebrates.

163 ance, the roles of photosensitive molecules, visual pigments, in arrhythmic vision are not well under

164 Absorption of light by visual pigments initiates the phototransduction pathway

165 such as Drosophila or Limulus assemble their visual pigment into the specialized rhabdomeric membrane

166 ng the shift of the absorption maxima when a visual pigment is converted to its lumirhodopsin photoin

167 As visual pigment is destroyed, or bleached, by light, cone

168 The chromophore of visual pigments is 11-cis-retinal and, thus, in its abse

169 onstrate that the primary counterion of cone visual pigments is necessary for efficient Schiff base h

170 the enzymatic pathway regenerating bleached visual pigments is present in vertebrate but not inverte

171 The light absorbing chromophore in opsin visual pigments is the protonated Schiff base of 11-cis-

172 upted and 11-cis-retinal, the chromophore of visual pigments, is not produced.

173 ation of 11-cis-retinal, the chromophore for visual pigments, is required for cones to continuously f

174 mount of 9-cis retinal and its corresponding visual pigment isorhodopsin.

175 lian rods and cones, light activation of the visual pigments leads to release of the chromophore, whi

176 retinal, a functional iso-chromophore of the visual pigments, led to alleviation of S-opsin mislocali

177 Visual-pigment levels increased to approximately 10 pmol

178 o changes in light intensity and color using visual pigment-like sensory rhodopsins (SRs).

179 mistry, arrestin binding and turnover of the visual pigments located in the various photoreceptor typ

180 Most deep-sea fish have a single visual pigment maximally sensitive at short wavelengths,

181 nctional diversification of the UV-sensitive visual pigments may help explain why the yellow wing pig

182 Rhodopsin (RH1), the temperature-sensitive visual pigment mediating dim-light vision, offers an opp

183 Rhodopsin, the visual pigment mediating vision under dim light, is comp

184 The visual pigment melanopsin is expressed in intrinsically

185 In mouse, this intrinsic PLR requires the visual pigment melanopsin; it also requires PLCbeta4, a

186 Light distributes the visual pigment, melanopsin, across three states, two sil

187 (connecting cilia) with outer segments, and visual pigments mistrafficked.

188 The signaling properties of the visual pigments modulate many aspects of the function of

189 ts (COSs), the labeled components--primarily visual pigment molecules (opsins)--are diffusely distrib

190 wed with the ability to detect light through visual pigments must have evolved pathways in which diet

191 on than the mouse short wavelength sensitive visual pigment (MUV) and photobleaching properties that

192 rmal reactions of the mouse short-wavelength visual pigment (MUV) were studied by using cryogenic UV-

193 antly throughout life, and which contain the visual pigments necessary for photon capture.

194 s and functional investigation of vertebrate visual pigments, numerous amino acid substitutions impor

195 this shift for the long-wavelength sensitive visual pigment of chicken iodopsin (lambdamax = 571 nm),

196 Hence, melanopsin is most likely the visual pigment of phototransducing RGCs that set the cir

197 lar co-expression of rhabdomeric opsin and a visual pigment of the recently described xenopsins in la

198 coding a putative ultraviolet (UV)-sensitive visual pigment of the Tokay gecko (Gekko gekko).

199 e photoexcited state of rhodopsin (Rh*), the visual pigment of vertebrate rods.

200 zed that the UV-, blue-, and green-sensitive visual pigments of insects were present in the common an

201 accounts for a 10-17-nm absorption shift in visual pigments of this class.

202 Regeneration of visual pigments of vertebrate rod and cone photoreceptor

203 der blue cones and green rods share the same visual pigment, only blue cones but not green rods are a

204 Their visual pigments (opsins) are activated by light, transdu

205 at short wavelengths was masked by the main visual pigment or because the expression level of a comp

206 history, and there is a direct link between visual pigment phenotypes and opsin genotypes.

207 tudy we evaluated two biochemical processes, visual pigment phosphorylation and transducin translocat

208 Although visual pigments play key structural and functional roles

209 We conclude that the MUV-visual pigment possesses an unprotonated retinylidene Sc

210 Bleached visual pigment produced an acceleration of the rod photo

211 er flash bleaching a large proportion of the visual pigment produced an ERC, which at 37 degrees C co

212 he promoter and the LCR, the identity of the visual pigment promoter, and LCR copy number.

213 e types is controlled by competition between visual pigment promoters for pairing with the LCR, and t

214 nd comparison of vertebrate and invertebrate visual pigment properties in a common cell type.

215 that RA has no effect on opsin expression or visual pigment properties in the differentiated retina o

216 However, OS formation and targeting of the visual pigment protein is severely disrupted.

217 The visual pigment protein of vertebrate rod photoreceptors,

218 Both classes use some form of the visual pigment protein opsin, which together with 11-cis

219 ion relies on the differential expression of visual pigment proteins (opsins) in cone photoreceptors

220 n rate of transducin (Tr) by light-activated visual pigment (R*) is 5-fold lower in carp cones than i

221 is critical for several processes, including visual pigment regeneration and retinal attachment to th

222 cking opsin, suggesting a connection between visual pigment regeneration and the retinoid cycle.

223 membranes in excess of what is required for visual pigment regeneration is not known.

224 ne-specific retinoid cycle required for cone visual pigment regeneration with the use of 11-cis-retin

225 step in a metabolic cycle that culminates in visual pigment regeneration.

226 there was no major impairment of the rate of visual pigment regeneration.

227 e results indicate that light contributes to visual-pigment renewal in mammalian rods and cones throu

228 oise and spectral shifting in Baikal cottoid visual pigments resulting in adaptations that enable vis

229 In contrast to visual pigments, RGR is bound predominantly to endogenou

230 ted mutations that lead to misfolding of the visual pigment rhodopsin (Rho) are a prominent cause of

231 nent of these rod discs, the light-sensitive visual pigment rhodopsin (Rho), consists of an opsin pro

232 nd G protein function comes from work on the visual pigment rhodopsin and its G protein transducin, w

233 uter rod segments are highly enriched in the visual pigment rhodopsin and the omega-3 fatty acid doco

234 receptors are represented by the vertebrate visual pigment rhodopsin and the yeast alpha-factor pher

235 The remarkable reactivity of RPSB in the visual pigment rhodopsin has been attributed to potentia

236 between transmembrane helices stabilize the visual pigment rhodopsin in an inactive conformation in

237 Activation of the visual pigment rhodopsin is caused by 11-cis to -trans i

238 ion of the 11-cis retinal chromophore in the visual pigment rhodopsin is coupled to motion of transme

239 The visual pigment rhodopsin is found predominantly in membr

240 to retinal chromophore isomerization in the visual pigment rhodopsin is studied using picosecond tim

241 The visual pigment rhodopsin is unique among the G protein-c

242 Visual pigment rhodopsin provides a decisive crossing po

243 It is a deeply engrained notion that the visual pigment rhodopsin signals light as a monomer, eve

244 ion of the 11-cis-retinal chromophore in the visual pigment rhodopsin triggers displacement of the se

245 the 11-cis retinyl chromophore in vertebrate visual pigment rhodopsin, a process that produces noise

246 of reactions that regenerate the vertebrate visual pigment rhodopsin, is the reduction of all-trans

247 disc membranes that are densely packed with visual pigment rhodopsin.

248 to all-trans isomerization of retinal in the visual pigment rhodopsin.

249 G protein, transducin, mediates between the visual pigment, rhodopsin, and the effector enzyme, cGMP

250 r segments results in the destruction of the visual pigment, rhodopsin, as its retinyl moiety is phot

251 ansduction is the phosphorylation of the rod visual pigment, rhodopsin, catalyzed by G-protein-depend

252 Here, we investigated whether the visual pigment, rhodopsin, is critical for delivering ot

253 by the extremely stable character of the rod visual pigment, rhodopsin, which evolved from less stabl

254 chromophore as the mammalian photoreceptor's visual pigment-rhodopsin.

255 Its eye is known to contain three visual pigments, rhodopsins, produced by an 11-cis-3-hyd

256 h rapid sectorial cone degeneration, and the visual pigments, S-opsin and M/L-opsin, fail to traffic

257 Both species have three types of visual pigment sensitive to short (SWS; wavelength of ma

258 n possess image-forming compound eyes with a visual pigment sensitive to the blue light of mesopelagi

259 Microspectrophotometry of LWS cone and rod visual pigments shows peak spectral sensitivities at 544

260 In the absence of a red-sensitive visual pigment, some deep-sea fish use a chlorophyll der

261 Surveys of spectral sensitivities, visual pigment spectra, and opsin gene sequences have in

262 vely selected sites correspond to vertebrate visual pigment spectral tuning residues.

263 ouse eventually regenerated normal levels of visual pigments, suggesting that RDHs compensate for eac

264 Short-wavelength cone visual pigments (SWS1) are responsible for detecting lig

265 Short-wavelength visual pigments (SWS1) have lambda(max) values that rang

266 de is regulated by quickly switching off the visual pigment that acts as the receptor for light.

267 isms for handling retinoids and regenerating visual pigment that are specific to photoreceptor type.

268 receptors of transgenic Drosophila yielded a visual pigment that bound retinal, had normal spectral p

269 in vertebrates is mediated by UV and violet visual pigments that absorb light maximally (lambdamax)

270 F45L, V209M and F220C-yield fully functional visual pigments that bind the 11-cis retinal chromophore

271 tion in long wavelength-absorbing Drosophila visual pigments that occurs at a site corresponding to A

272 The visual pigments that underlie the photosensitivity of th

273 activation kinetic constant (k) of different visual pigments (the Barlow correlation) indicates that

274 INTS: Following substantial bleaching of the visual pigment, the desensitization of the rod photovolt

275 gest that in short-wavelength sensitive cone visual pigments, the counterion is necessary for the cha

276 vertebrate (bovine) and invertebrate (squid) visual pigments, the mechanism of molecular rearrangemen

277 ces of the ancestral pigments of 11 selected visual pigments: the LWS pigments of cave fish (Astyanax

278 Like all visual pigments, this class has an 11-cis-retinal chromo

279 but requisite step in the restoration of the visual pigment to its ground state.

280 e to all-trans-retinal and conversion of the visual pigment to the signaling form.

281 Transducins couple visual pigments to cGMP hydrolysis, the only recognized

282 ucture largely determines the sensitivity of visual pigments to different wavelengths of light.

283 The results demonstrate that visual pigments transport to the retinal outer segment d

284 the retinal chromophore in both rod and cone visual pigments undergoes reversible Schiff base hydroly

285 Visual pigment (VP) expression in the chick embryo retin

286 etina, and a corresponding middle-wavelength visual pigment was observed.

287 etinal, and the lambda(max) of the resulting visual pigment was shown to be 359nm.

288 te (bovine, monkey) and invertebrate (squid) visual pigments was carried out using a hybrid quantum m

289 Despite their importance to the synthesis of visual pigment, we show that these genes are not active

290 sequences and absorption spectra of various visual pigments, we can identify amino acid changes that

291 evels of 11-cis-retinal, the chromophore for visual pigments, were significantly lower in diabetic re

292 efore and after bleaching most of the native visual pigment, which mainly has the 11-cis-3,4-dehydror

293 UV vision is mediated by UV-sensitive visual pigments, which have the wavelengths of maximal a

294 ration of 11-cis retinal, the chromophore of visual pigments, which represents a unique mechanism by

295 ound the chromophore and formed a bleachable visual pigment with lambda(max) of 492 nm that supported

296 s indicate that all-trans-retinal can form a visual pigment with opsin, through both protonated and u

297 valuate whether all-trans-retinal can form a visual pigment with rod opsin apoprotein.

298 avelength of the absorption maximum of their visual pigments with increasing habitat depth.

299 at have been observed recently in artificial visual pigments with synthetic retinylidene chromophores

300 sess a corresponding number of photoreceptor visual pigments, with peak absorbance ranging from 369 t

301 hromophore dissociates from cone but not rod visual pigment, yielding apo-opsin.