ライフサイエンスコーパス: vitamin D response element

1 ts, and four NF-kappaB binding sites, but no vitamin D response element.

2 AP-1 site and an element homologous to other vitamin D response elements.

3 eceptor complex binding to mouse osteopontin vitamin D response element (-70.2 +/- 4.9%, P < 0.001).

4 Both a Runx2 site (-136/-130) and the vitamin D response element (-757/-743) in the OPN promot

5 hin the human RANKL gene contained a similar vitamin D response element and exhibited an equivalent b

6 loss of DNase I-hypersensitive sites at the vitamin D response element and over the proximal tissue-

7 vities to an unusual but functionally active vitamin D response element and to several potential GC r

8 was abolished by mutagenesis of the putative vitamin D response elements and was enhanced by overexpr

9 n of a non-vitamin D receptor (VDR)-related, vitamin D response element-binding protein (VDRE-BP) and

10 ments in this region abolished VDR-RXR alpha-vitamin D response element complex formation.

11 In contrast, mutation of the vitamin D response element did not reduce basal expressi

12 The vitamin D response element from the involucrin gene boun

13 Sites A and B flank the vitamin D response element in the distal promoter and si

14 We conclude that the AP-1 site and the vitamin D response element in the involucrin promoter pl

15 endent, manner, and we identify a functional vitamin D response element in the p21 promoter.

16 functions through the coordinate binding of vitamin D response elements in the DNA and specific coac

17 urs at the transcriptional level through two vitamin D response elements in the promoter of the gene.

18 The regulatory complex is assembled on vitamin D response elements in the proximal promoter of

19 ction of vitamin D receptor binding with the vitamin D-response elements in the promoter of the gene

20 CYP3A9 promoter and identified one proximal vitamin D response element located at -119 to -133 from

21 t of the 1,25(OH)2D3 response, and two other vitamin D response elements located at -726 to -744 and

22 ectively as wild type VDR but did not induce vitamin D response element-mediated transcription.

23 sed histone H4 acetylation at the identified vitamin D response element of the murine and human MKP-1

24 ts heterodimeric partner RXR to the negative vitamin D response element on the promoter of Smad7, whi

25 inding of these receptors to the osteopontin vitamin D response element (OP VDRE).

26 nscriptional repression through the putative vitamin D response element present in the 5' regulatory

27 vitamin D3 on involucrin expression, but the vitamin D response element provides specificity for the

28 y transcriptional activity with a luciferase-vitamin D response element reporter construct.

29 We further identify a functional vitamin D response element (VDRE) 5-AGATAACAAAGGTCA-3 in

30 ophan hydroxylase 2 (TPH2) in the brain at a vitamin D response element (VDRE) and represses the tran

31 The induction occurred via a consensus vitamin D response element (VDRE) in the CAMP promoter t

32 rlier report in the literature indicated the vitamin D response element (VDRE) in the human parathyro

33 dentify YY1 recognition sequences within the vitamin D response element (VDRE) of the osteocalcin gen

34 A binding site, the vitamin D response element (VDRE), for a heterodimer of

35 uble-stranded DNA and function in trans as a vitamin D response element (VDRE)-binding protein.

36 id X receptor (RXR) dimer for binding to the vitamin D response element (VDRE).

37 not enhanced in the absence of a functional vitamin D response element (VDRE).

38 D(3) [1,25(OH)(2)D(3)] involves occupancy of vitamin D response elements (VDREs) by the VDRE binding

39 y shift analyses of the VDR DBD with several vitamin D response elements (VDREs) in the absence of ac

40 We identified and characterized vitamin D response elements (VDREs) located in both gene

41 receptor (RXR) heterodimer that binds to two vitamin D response elements (VDREs) located near the pro

42 (VDR) binds to specific DNA sequences termed vitamin D response elements (VDREs) thereby enhancing or

43 use nephrin gene identified several putative vitamin D response elements (VDREs), and EMSA confirmed

44 is element does not contain any recognizable vitamin D response elements (VDREs), high affinity DNA b

45 tinoid X receptor beta (RXR beta) binding to vitamin D response elements (VDREs), two thyroid hormone

46 th the 9-cis retinoic acid receptor (RXR) on vitamin D response elements (VDREs).

47 e by directly binding to and transactivating vitamin D-response elements (VDREs) within its promoter.

48 XR) to mouse osteopontin and rat osteocalcin vitamin D-response elements (VDREs).

49 A functional vitamin D response element was defined in the 5-prime re

50 A DR3-type vitamin D response element was identified in the fourth

51 tion of the involucrin promoter, whereas the vitamin D response element was not critical for calcium

52 bind as a homodimer to the osteopontin gene vitamin D response element, we find that a RXR-VDR heter

53 Potential vitamin D response elements were identified within promo

54 We also identified a putative positive vitamin D response element within the MKP5 promoter that

55 rizes with retinoic acid X receptors to bind vitamin D-response elements within the PTH gene.