ライフサイエンスコーパス: vitamin K epoxide reductase

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1 orthologs of gamma-glutamyl carboxylase and vitamin K epoxide reductase.

2 oexpressing the recently identified gene for vitamin K epoxide reductase.

3 mplicate the bacterial homolog of the enzyme vitamin K epoxide reductase, a protein required for bloo

4 macromolecular interactions by inhibition of vitamin K epoxide reductase, cellular responses includin

5 n dosing is correlated with polymorphisms in vitamin K epoxide reductase complex 1 (VKORC1) and the c

6 Variants in the gene encoding vitamin K epoxide reductase complex 1 (VKORC1) may affec

7 Vitamin K epoxide reductase complex subunit 1 (VKORC1) r

8 on its interaction with a splice variant of vitamin K epoxide reductase complex subunit 1 (VKORC1),

9 mented but uncharacterized splice variant of vitamin K epoxide reductase complex subunit 1 (VKORC1),

10 ctions of vIL-6 with the ER membrane protein vitamin K epoxide reductase complex subunit 1 variant 2

11 eviously uncharacterized ER membrane protein vitamin K epoxide reductase complex subunit 1 variant 2

12 ociates with a novel membrane protein termed vitamin K epoxide reductase complex subunit 1 variant 2

13 largely uncharacterized ER-resident protein vitamin K epoxide reductase complex subunit 1 variant 2

14 ide polymorphisms in cytochrome P450 2C9 and vitamin K epoxide reductase have been shown to make sign

15 Vitamin-K epoxide reductase is encoded by the VKORC1 gen

16 on (Ci-Gla1, gamma-glutamyl carboxylase, and vitamin K epoxide reductase) or spatiotemporal regulatio

17 arfarin and other 4-hydroxycoumarins inhibit vitamin K epoxide reductase (VKOR) by depleting reduced

18 Vitamin K epoxide reductase (VKOR) catalyzes the convers

19 oralis, and revealed the essential role of a vitamin K epoxide reductase (VKOR) gene in pilus assembl

20 Vitamin K epoxide reductase (VKOR) generates vitamin K h

21 isms in the cytochrome P450 2C9 (CYP2C9) and vitamin K epoxide reductase (VKOR) genes have been shown

22 Vitamin K epoxide reductase (VKOR) is an essential enzym

23 Vitamin K epoxide reductase (VKOR) is essential for the

24 Vitamin K epoxide reductase (VKOR) is the target of warf

25 Subsequently, vitamin K epoxide reductase (VKOR) is thought to convert

26 The warfarin-sensitive enzyme vitamin K epoxide reductase (VKOR) of the cycle reduces

27 The intramembrane vitamin K epoxide reductase (VKOR) supports blood coagul

28 Vitamin K epoxide reductase (VKOR) sustains blood coagul

29 Despite its importance, warfarin's target, vitamin K epoxide reductase (VKOR), has resisted purific

30 agulation in humans requires the activity of vitamin K epoxide reductase (VKOR), the target of the an

31 K is in excess in both the untransfected and vitamin K epoxide reductase (VKOR)-transfected cells, th

32 ts quiescin-sulfhydryl oxidase 1 (QSOX1) and vitamin K epoxide reductase (VKOR).

33 Warfarin-resistant vitamin K epoxide reductase (VKOR-Y139F) supported carbo

34 Using the mammalian membrane protein vitamin K epoxide reductase (VKORc1) as a reporter, we d

35 rphisms in the cytochrome P450 (CYP) 2C9 and vitamin K epoxide reductase (VKORC1) genes.

36 d of a key pharmacologic target of warfarin, vitamin K epoxide reductase (VKORC1), contribute to diff

37 logous to the catalytic subunit of mammalian vitamin K epoxide reductase (VKORC1, EC 1.1.4.1) that is

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