ライフサイエンスコーパス: voltage-gated sodium channel

1 ic causes are mutations in Nav1.1 (SCN1A), a voltage-gated sodium channel.

2 l excitability and affects the function of a voltage-gated sodium channel.

3 The para gene encodes a voltage-gated sodium channel.

4 n (c.4447G>A; p.E1483K) in SCN8A, encoding a voltage-gated sodium channel.

5 between activation and fast inactivation in voltage-gated sodium channels.

6 ing p38 MAPK-mediated negative modulation of voltage-gated sodium channels.

7 and fails to recruit neurofascin as well as voltage-gated sodium channels.

8 in the immature brain through alteration of voltage-gated sodium channels.

9 clusters for gliomedin, neurofascin-186, and voltage-gated sodium channels.

10 cytes, or functional sensory neurons showing voltage-gated sodium channels.

11 m mice or rats with expression constructs of voltage-gated sodium channels.

12 action between the delta-opioid receptor and voltage-gated sodium channels.

13 durans is a bacterial homologue of mammalian voltage-gated sodium channels.

14 ibution from entry through NMDA receptors or voltage-gated sodium channels.

15 rom wild-type and epilepsy-associated mutant voltage-gated sodium channels.

16 latus that delays inactivation of vertebrate voltage-gated sodium channels.

17 om tarantula venom able to inhibit the human voltage-gated sodium channel 1.7 (hNaV1.7), a channel re

18 The prominent role of voltage-gated sodium channel 1.7 (Nav1.7) in nociception

19 The voltage-gated sodium channel 1.7 (Nav1.7) plays an impor

20 ipheral expression of tetrodotoxin-resistant voltage-gated sodium channel 1.8 (NaV1.8) has been shown

21 , in mice, this effect is mediated solely by voltage-gated sodium channel 1.8 (NaV1.8).

22 The location of the gate in voltage-gated sodium channels, a founding member of this

23 Cone snail toxins are well known blockers of voltage-gated sodium channels, a property that is of bro

24 g shift of tetrodotoxin-sensitive persistent voltage-gated sodium channel activation.

25 eatment causes a large depolarizing shift of voltage-gated sodium channel activation/inactivation and

26 Voltage-gated sodium channel activators may accordingly

27 annels, Kir2.1 and dORKDelta-C) or decreased voltage-gated sodium channel activity (using mutations i

28 NRG1 are primarily attributable to decreased voltage-gated sodium channel activity, as current densit

29 maging in rat slices, we find that dendritic voltage-gated sodium channels allow somatic action poten

30 The mutations in the coding region of voltage-gated sodium channel alpha 1 subunit gene, SCN1A

31 However, expression analysis of voltage-gated sodium channel alpha subunits revealed NaV

32 a2-subunits in the ventricle is to chaperone voltage-gated sodium channel alpha-subunits to the plasm

33 inactivated conformational cycle in a single voltage-gated sodium channel and give insight into the s

34 sity accommodate the atomic coordinates of a voltage-gated sodium channel and of the beta subunit in

35 lication of thrombin did not alter transient voltage-gated sodium channels and action potential thres

36 slow inactivation of tetrodotoxin-resistant voltage-gated sodium channels and also enhances persiste

37 te loss of nodal protein staining, including voltage-gated sodium channels and ankyrin G, occurs and

38 enous cannabinoids have been shown to target voltage-gated sodium channels and cannabidiol has recent

39 but allosterically coupled receptor sites on voltage-gated sodium channels and cause persistent chann

40 n II and to the pore module of domain III in voltage-gated sodium channels and enhance channel activa

41 s required for the interaction of FGF14 with voltage-gated sodium channels and neuronal excitability.

42 rs and not through NMDA receptors or through voltage-gated sodium channels and that the spine neck is

43 iled electrophysiological protocols to study voltage-gated sodium channels and to investigate how wil

44 Sequence similarities between voltage-gated sodium channels and voltage-gated calcium

45 led the peptide's putative molecular target (voltage-gated sodium channels) and mechanism of action (

46 eurofascin, neuronal cell adhesion molecule, voltage-gated sodium channels, and actin filaments.

47 ts, at least in part, through its actions on voltage-gated sodium channels, and resurgent current may

48 urons, which express a unique combination of voltage-gated sodium channels; and (3) heterologously ex

49 Mammalian voltage-gated sodium channels are composed of four homol

50 Voltage-gated sodium channels are critical determinants

51 ABSTRACT: Voltage-gated sodium channels are critical for neuronal

52 Activation and inactivation of voltage-gated sodium channels are critical for proper el

53 Voltage-gated sodium channels are crucial determinants o

54 Voltage-gated sodium channels are crucial determinants o

55 Fast opening and closing of voltage-gated sodium channels are crucial for proper pro

56 Voltage-gated sodium channels are essential for electric

57 Voltage-gated sodium channels are important targets for

58 Voltage-gated sodium channels are inhibited by many loca

59 Voltage-gated sodium channels are required for the initi

60 Voltage-gated sodium channels are responsible for action

61 However, when voltage-gated sodium channels are temporarily blocked, c

62 Voltage-gated sodium channels are the primary target of

63 The mechanism by which voltage-gated sodium channels are trafficked to the surf

64 Voltage-gated sodium channels are vital membrane protein

65 Variants in SCN10A, which encodes a voltage-gated sodium channel, are associated with altera

66 muscle channel (SCN4A), encoding the Nav1.4 voltage-gated sodium channel, are causative of a variety

67 These results show that BBG inhibits voltage-gated sodium channels at micromolar concentratio

68 l isoform of Neurofascin, Nfasc186, clusters voltage-gated sodium channels at nodes of Ranvier in mye

69 elinated axons requires the concentration of voltage-gated sodium channels at nodes of Ranvier.

70 myelinated nerves requires the clustering of voltage-gated sodium channels at nodes of Ranvier.

71 The clustering of voltage-gated sodium channels at the axon initial segmen

72 myelinating Schwann cells, such as clustered voltage-gated sodium channels at the node of Ranvier and

73 deficient for exon 1b, PV interneurons lack voltage-gated sodium channels at their axonal initial se

74 e secretases also regulate the processing of voltage-gated sodium channel auxiliary beta-subunits and

75 GIC behavior, we addressed how the bacterial voltage-gated sodium channel (BacNa(V)) C-terminal cytop

76 es of members of a large family of bacterial voltage-gated sodium channels (BacNa(V)s) prevalent in s

77 Bacterial voltage-gated sodium channels (BacNavs) serve as models

78 omologous factors (FHFs) bound to axosomatic voltage-gated sodium channels bear an N-terminal blockin

79 Identified genes included voltage-gated sodium channel beta subunits, potassium ch

80 d the localization of nodal proteins such as voltage-gated sodium channels, beta IV spectrin and CASP

81 Mutations in SCN2B, encoding voltage-gated sodium channel beta2-subunits, are associa

82 nts revealed that Ae1a potently inhibits the voltage-gated sodium channel BgNaV1 from the German cock

83 activated via intravitreal injections of the voltage-gated sodium channel blocker, tetrodotoxin (TTX)

84 Tetrodotoxin (TTX) is a potent blocker of voltage-gated sodium channels, but not all sodium channe

85 teractions between scaffolding molecules and voltage-gated sodium channels, but the molecular mechani

86 tion, pyridine nucleotides also modulate the voltage-gated sodium channel by supporting the activity

87 ar architecture, and normal concentration of voltage-gated sodium channels by [(3)H]-saxitoxin bindin

88 f cone snails, known as mu-conotoxins, block voltage-gated sodium channels by physically occluding th

89 Key among them is the voltage-gated sodium channel complex.

90 Voltage-gated sodium channels control the upstroke of th

91 des (P<0.0001), with altered architecture of voltage-gated sodium channel distribution.

92 in a reduction in the fraction of available voltage-gated sodium channels due to insufficient recove

93 polychlorocyclohexanes and fiproles, and the voltage-gated sodium channel for pyrethroids and dichlor

94 ocytes of the first non-insect, invertebrate voltage-gated sodium channel from the varroa mite (Varro

95 complexes often considered independent: the voltage-gated sodium channel, gap junctions, and the car

96 T. urticae populations and a mutation in the voltage-gated sodium channel gene (F1538I) in 66.7% popu

97 n Culex quinquefasciatus display CNV for the voltage-gated sodium channel gene (Vgsc), target-site of

98 gous loss-of-function mutations in the brain voltage-gated sodium channel gene SCN1A.

99 De novo mutations of the voltage-gated sodium channel gene SCN8A have recently be

100 caused by de novo missense mutations in the voltage-gated sodium channel gene SCN8A Here, we investi

101 eased in number in larvae that have a mutant voltage-gated sodium channel gene, scn8aa.

102 e mutation (c.5302A>G [p.Asn1768Asp]) in the voltage-gated sodium-channel gene SCN8A in the proband.

103 erity have been associated with mutations in voltage-gated sodium channel genes.

104 minal residues 1777-1882 of the human NaV1.2 voltage-gated sodium channel has been determined in solu

105 Although a gate residue in the eukaryotic voltage-gated sodium channel has been identified, the mi

106 Slow inactivation of voltage-gated sodium channels has been discussed to be t

107 The activity of voltage-gated sodium channels has long been linked to di

108 Mutations in brain isoforms of voltage-gated sodium channels have been identified in pa

109 Voltage-gated sodium channels have essential roles in el

110 alanine 1486 (F1486del) in the human cardiac voltage-gated sodium channel (hNav1.5) is associated wit

111 trocytes in vitro have been shown to express voltage-gated sodium channels in a dynamic manner, with

112 Human studies have firmly implicated voltage-gated sodium channels in human pain disorders, a

113 oal was to examine the role of intracellular voltage-gated sodium channels in macrophage function.

114 tivity regulates total and surface levels of voltage-gated sodium channels in mouse brains.

115 hree disulfide bridges, is a pore blocker of voltage-gated sodium channels, including neuronal subtyp

116 Voltage-gated sodium channels initiate action potentials

117 Voltage-gated sodium channels initiate action potentials

118 Voltage-gated sodium channels initiate action potentials

119 Voltage-gated sodium channels initiate electrical signal

120 Voltage-gated sodium channels initiate the rapid upstrok

121 The Nav1.1 voltage-gated sodium channel is a critical contributor t

122 The ion translocation process seen in this voltage-gated sodium channel is clearly different from t

123 The NaV1.7 voltage-gated sodium channel is implicated in human pain

124 Ion permeation through voltage-gated sodium channels is modulated by various dr

125 Partial blockade of voltage-gated sodium channels is neuroprotective in expe

126 Inhibition of voltage-gated sodium channels is neuroprotective in prec

127 gia, the first human pain syndrome linked to voltage-gated sodium channels, is widely regarded as a g

128 The Na(V)1.7 tetrodotoxin-sensitive voltage-gated sodium channel isoform plays a critical ro

129 The Na(v)1.2 and Na(v)1.3 voltage-gated sodium channel isoforms demonstrate distin

130 Na(v)1.2 and Na(v)1.6 are two voltage-gated sodium channel isoforms found in adult CNS

131 1-type sodium channels and to substitute for voltage-gated sodium channels lacking in many invertebra

132 utations in Nav.1.7, the main pain signaling voltage-gated sodium channel, lead to its truncations an

133 ive axonal potentials that are maintained by voltage-gated sodium channels, leading to a declination

134 hether manipulation of splicing of mammalian voltage-gated sodium channels may be exploitable to prov

135 e results suggest that altered processing of voltage-gated sodium channels may contribute to aberrant

136 ular determinants of toxin interactions with voltage-gated sodium channels may permit development of

137 Axonal voltage-gated sodium channel mRNA and local trafficking

138 ant mutations in the SCN1A gene encoding the voltage-gated sodium channel Na(v) 1.1.

139 ve heterozygous mutations in SCN1A, encoding voltage-gated sodium channel Na(v)1.1 alpha subunits.

140 mutations in the alpha subunit of the type I voltage-gated sodium channel Na(V)1.1 cause severe myocl

141 aploinsufficiency of the SCN1A gene encoding voltage-gated sodium channel Na(V)1.1 causes Dravet's sy

142 e contribution of elevated BACE1 activity to voltage-gated sodium channel Na(v)1.1 density and neuron

143 migraine disorder caused by mutations in the voltage-gated sodium channel Na(V)1.1 encoded by SCN1A.

144 Mutations in SCN1A, encoding the voltage-gated sodium channel Na(V)1.1, are the most comm

145 The function of the human voltage-gated sodium channel Na(V)1.5 is regulated in pa

146 8J) allele of the gene encoding the neuronal voltage-gated sodium channel Na(v)1.6.

147 Gain-of-function missense mutations of voltage-gated sodium channel Na(V)1.7 have been linked t

148 The voltage-gated sodium channel Na(V)1.7 is believed to be

149 The voltage-gated sodium channel Na(v)1.7 plays a crucial ro

150 FN for mutations in the SCN9A gene, encoding voltage-gated sodium channel Na(V)1.7, which is preferen

151 n in heterologous cells transfected with the voltage-gated sodium channel Na(V)1.7.

152 The voltage-gated sodium channel Na(v)1.8 is known to functi

153 ination of a high-resolution 3D structure of voltage-gated sodium channel Na(V)Ab opens the way to el

154 ins, PIIIA, effectively blocks the bacterial voltage-gated sodium channel Na(V)Ab, whose crystal stru

155 Voltage-gated sodium channels Na(v)1.2 and Na(v)1.6 are

156 ch information learned in recent years about voltage gated sodium channel (Na(V)) subtypes in somatos

157 tudies show preferential localization of the voltage-gated sodium channel (Na(V)1.5) to this region.

158 The cardiac voltage-gated sodium channel (Na(V)1.5) underlies impuls

159 Human nociceptive voltage-gated sodium channel (Na(v)1.7), a target of sig

160 n dissection, that the Silicibacter pomeroyi voltage-gated sodium channel (Na(V)Sp1) PD forms a stand

161 Voltage-gated sodium channels (Na(v) channels) in retina

162 Voltage-gated sodium channels (Na(v)) underlie the rapid

163 alpha-toxins affect insect and/or mammalian voltage-gated sodium channels (Na(v)s) and thereby modif

164 The tremendous therapeutic potential of voltage-gated sodium channels (Na(v)s) has been the subj

165 Voltage-gated sodium channels (Na(V)s) provide the initi

166 Voltage-gated sodium channels (Na(V)s) underlie the upst

167 nefarious effects result from inhibition of voltage-gated sodium channels (Na(V)s), the obligatory p

168 uit of novel subtype-selective modulators of voltage-gated sodium channels (Na(v)s).

169 s of sodium conductance across membranes are voltage-gated sodium channels (Na(V)s).

170 r the ion transport function mediated by the voltage-gated sodium channel, Na(V)1.2.

171 nce-conferring amino acid substitutions in a voltage-gated sodium channel, Na(v)1.4, are clustered in

172 Voltage-gated sodium channels, Na(v)1.1-Na(v)1.9, are es

173 Three voltage-gated sodium channels, Na(v)1.7, Na(v)1.8, and N

174 quantify isoflurane binding to the bacterial voltage-gated sodium channel NaChBac.

175 ease responsible for proteolytic cleavage of voltage-gated sodium channels (NaChs).

176 ABSTRACT: Voltage-gated sodium channel NaV 1.7 is required for acu

177 binds to the domain II voltage sensor in the voltage-gated sodium channel Nav and modifies its voltag

178 Voltage-gated sodium channel (NaV) mutations cause genet

179 Voltage-gated sodium channel (NaV) trafficking is incomp

180 metabotropic glutamate receptor-1 (mGluR1), voltage-gated sodium channels (Nav ) and glutamate trans

181 Ts3 binds to the domain IV voltage sensor of voltage-gated sodium channels (Nav ) and slows down thei

182 phibian prey, which select for TTX-resistant voltage-gated sodium channels (Nav) [12-16].

183 They are rich in voltage-gated sodium channels (Nav) and thus underpin ra

184 myelinated nerves requires the clustering of voltage-gated sodium channels (Nav) at nodes of Ranvier

185 heless, Nfasc140, like Nfasc186, can cluster voltage-gated sodium channels (Nav) at the developing no

186 its slow activation) but assists recovery of voltage-gated sodium channels (Nav) from inactivation by

187 We examined the repertoire of voltage-gated sodium channels (NaV) in fluorescence-sort

188 mans and other vertebrates, target conserved voltage-gated sodium channels (NaV) of nerve and muscle,

189 Voltage-gated sodium channels (NaV) play an important ro

190 Voltage-gated sodium channels (Nav) produce sodium curre

191 ic tension, the thermal random motion of the voltage-gated sodium channels (Nav), which are bound to

192 Conotoxins act by inhibiting inactivation of voltage-gated sodium channels (Nav).

193 The beta1 subunit of voltage-gated sodium channels, Nav beta1, plays multiple

194 n the SCN1A gene, which encodes brain type-I voltage-gated sodium channel NaV1.1.

195 d by loss-of-function mutations in the brain voltage-gated sodium channel NaV1.1.

196 Mutations in SCN2A, a gene encoding the voltage-gated sodium channel Nav1.2, have been associate

197 Therefore, EC cells use Scn3a-encoded voltage-gated sodium channel NaV1.3 for electrical excit

198 ed a critical role for the regulation of the voltage-gated sodium channel NaV1.5 in the heart by the

199 The voltage-gated sodium channel NaV1.5 is responsible for t

200 SCN5A encodes the alpha-subunit of the voltage-gated sodium channel NaV1.5.

201 This is due to the voltage-gated sodium channel Nav1.7 (Scn9a), previously

202 issense mutations in the peripheral neuronal voltage-gated sodium channel Nav1.7 are implicated in th

203 ates that the expression and function of the voltage-gated sodium channel Nav1.7 are increased in a p

204 Mutations in the voltage-gated sodium channel Nav1.7 are linked to inheri

205 Human genetic studies have implicated the voltage-gated sodium channel NaV1.7 as a therapeutic tar

206 inflammatory pain requires the expression of voltage-gated sodium channel Nav1.7 but its significance

207 unction mutations in the SCN9A gene encoding voltage-gated sodium channel Nav1.7 cause congenital ins

208 Voltage-gated sodium channel Nav1.7 is a central player

209 Trafficking of the voltage-gated sodium channel NaV1.7 is dysregulated in n

210 The human voltage-gated sodium channel Nav1.7 plays a crucial role

211 Functional variants of voltage-gated sodium channel Nav1.7, encoded by SCN9A, h

212 iant in the second intracellular loop of the voltage-gated sodium channel NaV1.7, encoded by the SCN9

213 ndromes have been linked to mutations in the voltage-gated sodium channel Nav1.7.

214 Under physiological conditions, the voltage-gated sodium channel Nav1.8 is expressed almost

215 notoxins MrVIA, MrVIB, and MfVIA inhibit the voltage-gated sodium channel NaV1.8, a well described ta

216 dromes, and variants of genes coding for the voltage-gated sodium channels Nav1.8 (SCN10A) and Nav1.9

217 nsfer (LRET) between the rat skeletal muscle voltage-gated sodium channel (Nav1.4) and fluorescently

218 des the alpha-subunit of the skeletal muscle voltage-gated sodium channel (Nav1.4).

219 Gain-of-function mutations in the voltage-gated sodium channel (Nav1.5) are associated wit

220 examined the expression of all the neuronal voltage-gated sodium channels (Nav1.1, Nav1.2, Nav1.3, N

221 Cardiac voltage-gated sodium channels (Nav1.5) play an essential

222 ge-gated sodium channel (SCN5A gene encoding voltage-gated sodium channel [NaV1.5]) cause congenital

223 c evidence has clearly demonstrated that the voltage-gated sodium channel, Nav1.7, is critical to pai

224 multiple elements within the promoter of the voltage-gated sodium channel, Nav1.7, leading to a syner

225 The X-ray structure of the bacterial voltage-gated sodium channel NavAb has been reported in

226 enic mice, also cleaves the beta2-subunit of voltage-gated sodium channels (Navbeta2).

227 Voltage-gated sodium channels (NaVs) are activated by tr

228 Voltage-gated sodium channels (NaVs) are central element

229 It is characterized by the dysregulation of voltage-gated sodium channels (Navs) expressed in dorsal

230 Voltage-gated sodium channels (Navs) play crucial roles

231 Voltage-gated sodium channels (Navs) play essential role

232 Improper function of voltage-gated sodium channels (NaVs), obligatory membran

233 in part due to changes in the properties of voltage-gated sodium channels (Navs).

234 ty resulting from point mutations within the voltage-gated sodium channel of the insect nervous syste

235 These results suggest that sanshool targets voltage-gated sodium channels on Adelta mechanosensory n

236 ptic drug carbamazepine was found to inhibit voltage-gated sodium channels only with external, but no

237 nd directly the mRNA encoding the Drosophila voltage-gated sodium channel paralytic (para).

238 KEY POINTS: Voltage-gated sodium channels play a fundamental role in

239 Whereas voltage-gated sodium channels play a well known and impo

240 , molecular composition, and localization of voltage-gated sodium channels play major roles in a broa

241 ture of the open conformation of a bacterial voltage-gated sodium channel pore from Magnetococcus sp.

242 ut not blockers of AMPA/kainate receptors or voltage-gated sodium channels, prevented microglial outg

243 oltage dependence of the rat skeletal muscle voltage-gated sodium channel rNav1.4 expressed in oocyte

244 Mutations in the neuronal voltage-gated sodium channel SCN1A are associated with a

245 transgenes encoding a multisubunit neuronal voltage-gated sodium channel (SCN1A) containing a pore-f

246 revealed that the didy mutation disrupts the voltage-gated sodium channel Scn1lab (Nav1.lb).

247 Mutations of the cardiac voltage-gated sodium channel (SCN5A gene encoding voltag

248 tiated and propagated by a single isoform of voltage gated sodium channels - SCN5A.

249 euritis at concentrations at which it blocks voltage-gated sodium channels selectively.

250 perties were independent of modifications in voltage-gated sodium channels since 100 nM bifenthrin ha

251 Specifically, voltage-gated sodium channel subtype NaV 1.7 is required

252 tations in the human SCN1A gene encoding the voltage-gated sodium channel subunit Nav 1.1.

253 interneuron-specific and PV cell-predominant voltage-gated sodium channel subunit Nav1.1.

254 xpression of a human-specific isoform of the voltage-gated sodium channel subunit SCN4B was significa

255 CN10A, which encodes a nociceptor-associated voltage-gated sodium channel subunit, as a modulator of

256 ciated with the cleavage of Neuregulin and a voltage-gated sodium channel subunit.

257 the central nervous system (CNS) containing voltage-gated sodium channels targeted by deltamethrin.

258 n their synaptic development by delivering a voltage-gated sodium channel that triggers long depolari

259 Thus, structural properties of eukaryotic voltage-gated sodium channels that are suggested by func

260 ed and likely to have evolved from ancestral voltage-gated sodium channels that are widely expressed

261 that heterologously expressed human cardiac voltage-gated sodium channel, the principle cardiac sodi

262 knockdown, alter splicing of the Drosophila voltage-gated sodium channel to favour inclusion of exon

263 um2 is able to directly bind the predominant voltage-gated sodium channel transcript (NaV1.6) express

264 Voltage-gated sodium channels underlie the rapid regener

265 mutation in SCN11A, which encodes the Nav1.9 voltage-gated sodium channel, underlies a human disorder

266 es multiple components of the AIS, including voltage-gated sodium channels, up to 17 mum away from th

267 osequencing genotyping and sequencing of the voltage gated sodium channel (VGSC) gene did not detect

268 Voltage-gated sodium channel (VGSC) activity has previou

269 Voltage-gated sodium channel (VGSC) beta subunits signal

270 plasticity, we used brevetoxin-2 (PbTx-2), a voltage-gated sodium channel (VGSC) gating modifier, to

271 Veratridine (VTD) is a voltage-gated sodium channel (VGSC) modifier that is use

272 Voltage-gated sodium channel (VGSC) mutations cause seve

273 as PN3) is a tetrodotoxin-resistant (TTx-r) voltage-gated sodium channel (VGSC) that is highly expre

274 mutations L1014F and L1014S within the para voltage-gated sodium channel (VGSC).

275 -14) bind to the C termini (CTs) of specific voltage-gated sodium channels (VGSC) and thereby regulat

276 ated that the tetrodotoxin-resistant (TTX-R) voltage-gated sodium channels (VGSC) are preferentially

277 agnitude shorter than the activation time of voltage-gated sodium channels (VGSC) would evoke action

278 s to efficiently overexpress large mammalian voltage-gated sodium channels (VGSC).

279 f structural and functional relationships of voltage-gated sodium channels (VGSC).

280 sed to contribute to anesthetic effects, the voltage gated sodium channels (VGSCs) should also be con

281 ies of myelinated fibres, however, show that voltage-gated sodium channels (VGSCs) aggregate with cel

282 KCNQ2/3 (Kv7.2/7.3) channels and voltage-gated sodium channels (VGSCs) are enriched in th

283 Voltage-gated sodium channels (VGSCs) are essential to t

284 Voltage-gated sodium channels (VGSCs) are important for

285 Voltage-gated sodium channels (VGSCs) are responsible fo

286 benzyl-3-methoxypropanamide (LCM)) modulates voltage-gated sodium channels (VGSCs) by preferentially

287 We have recently demonstrated that voltage-gated sodium channels (VGSCs) in dorsal root gan

288 nodes of Ranvier are sites of clustering of voltage-gated sodium channels (VGSCs) in nervous systems

289 ntal and modeling studies have proposed that voltage-gated sodium channels (VGSCs) play an important

290 Voltage-gated sodium channels (VGSCs) regulate invasion

291 Clustering of voltage-gated sodium channels (VGSCs) within the neurona

292 ting the structure-function relationships of voltage-gated sodium channels (VGSCs).

293 Inherited mutations in voltage-gated sodium channels (VGSCs; or Nav) cause many

294 thrombin effect on neuronal excitability and voltage-gated sodium channels was assessed using extrace

295 Kidins220 association with brain voltage-gated sodium channels was shown by co-immunoprec

296 acts on various targets in vitro, including voltage-gated sodium channels, was initially proposed as

297 cing the primary pyrethroid target site, the voltage-gated sodium channel, we show that point mutatio

298 rt toxic effects by altering the function of voltage-gated sodium channels, which are essential for p

299 in mammals, nine genes encode nine distinct voltage-gated sodium channels with different amino acid

300 Blockade of voltage-gated sodium channels with TTX and reverse (Ca(2