ライフサイエンスコーパス: volvulus

1 h age (equivalent to years of exposure to O. volvulus).

2 s of multiple ivermectin doses on Onchocerca volvulus.

3 er blindness), which is caused by Onchocerca volvulus.

4 h Ags from the parasitic helminth Onchocerca volvulus.

5 s warranted to prevent obstruction or midgut volvulus.

6 apable of inducing protective immunity to O. volvulus.

7 acted from the parasitic helminth Onchocerca volvulus.

8 species Wuchereria bancrofti and Onchocerca volvulus.

9 es to the human helminth pathogen Onchocerca volvulus.

10 nous CV and SV, and 18% for transverse colon volvulus.

11 smitter-derived secretion metabolite from O. volvulus.

12 ailure to do so leads to gut malrotation and volvulus.

13 site representing the closest relative of O. volvulus.

14 ceived a clinical diagnosis other than cecal volvulus.

15 d split wall have high specificity for cecal volvulus.

16 complications of DPEJ, including small bowel volvulus.

17 ing enterocolitis, gastroschisis, and midgut volvulus.

18 obstruction is significantly associated with volvulus.

19 us (19 [59%] of 32) than in patients without volvulus (11 [16%] of 68) (P<.001).

20 ts was significantly higher in patients with volvulus (19 [59%] of 32) than in patients without volvu

21 n were transition points not associated with volvulus (31 [46%] of 68 patients) (P<.005).

22 erase from the parasitic nematode Onchocerca volvulus, a major cause of blindness in Africa.

23 ted that rOv-ASP-1, a recombinant Onchocerca volvulus activation associated protein-1, was a potent a

24 ously, and a soluble antigen extract from O. volvulus adult worms (OvAg) was injected into the cornea

25 In O. volvulus adult worms the Ov-SPI proteins are localized t

26 n and intracorneal injection with soluble O. volvulus Ags (OvAg), and that the inflammatory response

27 and injected intrastromally with Onchocerca volvulus Ags.

28 L3 and a recombinant L3-specific protein, O. volvulus ALT-1) which were significantly increased or ma

29 d significantly with age, although not to O. volvulus ALT-1, which may have unique L3-specific epitop

30 l punch' to knockout human infection with O. volvulus altogether.

31 6-100 years) with surgically confirmed cecal volvulus and 12 control patients were reviewed.

32 yosin from the tropical parasites Onchocerca volvulus and Brugia malayi.

33 Both recombinant O. volvulus and C. elegans cyclophilins were found to posse

34 Baseline statistical values for the cecal volvulus and control groups were analyzed by using a two

35 onse, and concurrent helminth infections (O. volvulus and intestinal helminths) may alter TT-specific

36 Coexisting volvulus and ischemia were diagnosed with low sensitivit

37 Here, we describe the chromosomes of O. volvulus and its Wolbachia endosymbiont.

38 Onchocerca volvulus and lymphatic filariae, causing river blindness

39 of the expressed sequence tag datasets of O. volvulus and other filariae identified four other member

40 a patient with short-gut syndrome caused by volvulus and severe cholestatic liver disease who underw

41 ochengi is the closest extant relative of O. volvulus and shares several key natural history traits w

42 matodes Acanthocheilonema viteae, Onchocerca volvulus, and Brugia malayi, strongly supporting the con

43 ne for diseases such as intestinal atresias, volvulus, and necrotizing enterocolitis.

44 rotizing enterocolitis, neutropenic colitis, volvulus, and sepsis.

45 Onchocerca volvulus antigen (OvAg)-stimulated peripheral blood mono

46 unoglobulin G4 to the recombinant Onchocerca volvulus antigen Ov-16 was modified to detect antibodies

47 ts IgG4 antibodies to recombinant Onchocerca volvulus antigen Ov16 with serum samples from patients w

48 The Onchocerca volvulus antigen Ov39 is cross-reactive with the retinal

49 cross-reactive antibodies to the Onchocerca volvulus antigen Ov39.

50 neal inflammation induced by Wolbachia or O. volvulus antigens containing Wolbachia is completely dep

51 olony-stimulating factor responses to all O. volvulus antigens unrelated to age.

52 and injected intrastromally with soluble O. volvulus antigens.

53 which Ags from the parasitic worm Onchocerca volvulus are injected into the corneal stroma.

54 Second, the bowel graft was prone to volvulus around the skeletonized donor portal vein.

55 ew the control and elimination of Onchocerca volvulus as a public health problem.

56 uld be guided by what is done for Onchocerca volvulus as there are no data for O. lupi.

57 a better understanding of the biology of O. volvulus as well as for the identification of novel targ

58 ae of the human filarial parasite Onchocerca volvulus, belongs to the family 18 glycosyl hydrolases a

59 To determine whether in utero exposure to O. volvulus biases a child's subsequent immune responses, c

60 O. volvulus blisterase expressed in insect cells has maxima

61 ssays with fluorescent peptides show that O. volvulus blisterase requires a P4 arginine and a basic a

62 s indicate that concurrent infection with O. volvulus can diminish the immune response to an unrelate

63 h the parasitic filarial nematode Onchocerca volvulus can lead to severe visual impairment and ultima

64 010 was retrospectively reviewed for colonic volvulus cases admitted emergently.

65 milar localization of the related Onchocerca volvulus cathepsin Z protein suggests that the function

66 We evaluated Onchocerca volvulus community microfilarial intensity and prevalenc

67 ivation, we injected a soluble extract of O. volvulus containing Wolbachia bacteria into the corneal

68 In addition, O. volvulus contains the rickettsial endosymbiont Wolbachia

69 mortality in cases of sigmoid (SV) and cecal volvulus (CV) taking into account preoperative and opera

70 gative for Mf: 16 (57%) were positive for O. volvulus DNA in the PCR-based assay.

71 s indicate that concurrent infection with O. volvulus does not prevent the development of a protectiv

72 hepsin L in the filarial nematode Onchocerca volvulus, eggshell and cuticle, suggests that some of th

73 ng an intrastromal injection of a soluble O. volvulus extract.

74 endosymbiotic Wolbachia in B. malayi and O. volvulus filaria are dependent on TLR2-TLR6 interactions

75 d were frequently complicated by small-bowel volvulus (five of 14) and bowel ischemia (six of 14).

76 Seven patients had volvulus; four had bowel ischemia.

77 ne protease in the development of Onchocerca volvulus fourth stage larvae (L4) by testing the effect

78 Other O. volvulus genes showed homology only to predicted genes f

79 We describe O. volvulus genome variation in 27 isolates from the early

80 Thus, in utero exposure to O. volvulus has a long-term effect on the child's subsequen

81 sfully the complete life cycle of Onchocerca volvulus has hindered progress towards unravelling the p

82 CT demonstrated signs of volvulus in four of six patients with ischemia.

83 une response to the filarial worm Onchocerca volvulus in humans.

84 rotective immunity against larval Onchocerca volvulus in mice depends on the development of a Th2 imm

85 e immune response to the larval stages of O. volvulus in mice immunized with irradiated larvae.

86 or adaptive protective immunity to larval O. volvulus in mice.

87 Ts and neutrophils were visualised around O. volvulus in nodules excised from untreated patients but

88 lbachia bacterial endosymbiont of Onchocerca volvulus in these reactions, serum samples collected bef

89 t of a protective immune response against O. volvulus in TLR4-mutant mice is not due to loss of Th2 i

90 inth that causes river blindness (Onchocerca volvulus) induces eosinophil recruitment to the corneal

91 ment of Onchocerca volvulus infection, 40 O. volvulus-infected Ghanaians were randomized to receive p

92 Stratification of the O. volvulus-infected group into two groups representing lig

93 cytokine, and antibody response to TT of O. volvulus-infected subjects (n = 19) and comparable nonin

94 unts were examined in 2 groups of Onchocerca volvulus-infected subjects after ivermectin treatment.

95 Onchocerca volvulus infection has been associated with impaired cel

96 general perception has been that Onchocerca volvulus infection is well on its way towards extinction

97 immune response, the effect of concurrent O. volvulus infection on the immune response to tetanus tox

98 may render the child more susceptible to O. volvulus infection postnatally.

99 humped pattern with host age, patterns of O. volvulus infection vary markedly with locality.

100 y and its potential mechanisms in Onchocerca volvulus infection were examined by analyzing cytokine a

101 vaccination in 193 subjects with Onchocerca volvulus infection with 85 comparable noninfected contro

102 reactions after the treatment of Onchocerca volvulus infection, 40 O. volvulus-infected Ghanaians we

103 bits high sensitivity and specificity for O. volvulus infection, and has great potential as a tool fo

104 an current methods for diagnosing Onchocerca volvulus infection, and it overcomes many difficulties i

105 are critical for establishment of Onchocerca volvulus infection, the third-stage larvae (L3) and the

106 jor cause of visual impairment in Onchocerca volvulus infection.

107 ve antitetanus response, although heavier O. volvulus infections are able to alter the magnitude of t

108 ith responses in 43 subjects with chronic O. volvulus infections.

109 und also to completely inhibit molting of O. volvulus infective L3 stage larvae.

110 ilation, band slippage, perforation, gastric volvulus, intraluminal band erosion, and port- and band-

111 Colonic volvulus is a rare cause of bowel obstruction in the Uni

112 Colonic volvulus is a rare entity associated with high mortality

113 Infection with Onchocerca volvulus is associated with the prevalence of severe vis

114 Targeting the Wolbachia in O. volvulus is effective in clearing microfilariae in the s

115 an individuals from an area where Onchocerca volvulus is hyperendemic have been monitored for infecti

116 The life expectancy of adult O. volvulus is reduced by approximately 50% and 70% after 3

117 When cecal volvulus is suspected, the absence of distal colonic dec

118 The filarial nematode Onchocerca volvulus is the causative organism of river blindness.

119 ria bancrofti) or onchocerciasis (Onchocerca volvulus) is doxycycline.

120 ate that CD4(+) T cells mediate sustained O. volvulus keratitis by regulating eosinophil recruitment

121 To examine the role of IFN-gamma in O. volvulus keratitis, C57BL/6 and IFN-gamma(-/-) mice were

122 rated that in the murine model of Onchocerca volvulus keratitis, neutrophils and eosinophils are recr

123 antibodies directed against a recombinant O. volvulus L3 cysteine protease that was cloned and expres

124 been found to be critical for molting in O. volvulus L3 larvae.

125 ophoric activity was capable of affecting O. volvulus L3 molting and that the presence of both activi

126 t of each of its biological activities on O. volvulus L3 molting was investigated.

127 a small number of patients infected with O. volvulus, M. perstans, or W. bancrofti showed positive i

128 Using a mouse model of Onchocerca volvulus-mediated keratitis (river blindness), the prese

129 Conversely, expression of ICAM-1 in O. volvulus-mediated keratitis was significantly reduced af

130 Our results demonstrate that NATOG tracks O. volvulus metabolism in both worms and humans, and thus c

131 examination for the detection of Onchocerca volvulus microfiladermia (2 of 218 samples positive by b

132 individual level, between infection with O. volvulus microfilariae and bilateral blindness was exami

133 ivermectin treatment in Ghana has reduced O. volvulus microfilarial intensity and prevalence, but sub

134 We have shown a direct relation between O volvulus microfilarial load and host mortality in a comp

135 Midgut volvulus (n=11) was the most common cause in the PG foll

136 mall-bowel obstruction (n=68) or small-bowel volvulus (n=32) were retrospectively identified.

137 ng's disease, necrotising enterocolitis, and volvulus neonatorum in 23 (45.1%) each.

138 munophenotyping approach to study Onchocerca volvulus (Ov) population diversity.

139 ructures and a protein present in Onchocerca volvulus (OV).

140 from the human parasitic nematode Onchocerca volvulus, Ov-SPI-1, was identified through the analysis

141 isolated from the human parasite Onchocerca volvulus (OvCYP-16).

142 itional significant independent predictor of volvulus (P<.05).

143 proved the specificity for cross-reactive O. volvulus patient sera (100% sensitivity and 100% specifi

144 duction in the percentage of adult female O. volvulus positive for Wolbachia) is 91%-94% on average,

145 g of an existing drug with impact against O. volvulus provides promise in the hunt for new therapies

146 ely, a Glu(124) (C. elegans) or Asp(123) (O. volvulus) residue present in a critical position.

147 While the serum levels of O. volvulus-specific immunoglobulin G (IgG), IgG subclasses

148 with L. loa, Mansonella perstans, Onchocerca volvulus, Strongyloides stercoralis, or Wuchereria bancr

149 e caused by the filarial nematode Onchocerca volvulus that affects more than 37 million people, mainl

150 e caused by the filarial nematode Onchocerca volvulus that can lead to blindness and chronic disabili

151 patterns of human infection with Onchocerca volvulus (the cause of river blindness) in different con

152 ltered the global distribution of Onchocerca volvulus, the agent of river blindness, and further popu

153 implicated in the development of Onchocerca volvulus, the causative agent of onchocerciasis.

154 antigen of the parasitic nematode Onchocerca volvulus, the causative agent of river blindness in huma

155 cludes filarial pathogens such as Onchocerca volvulus, the cause of human onchocerciasis, or river bl

156 Efforts to control Onchocerca volvulus, the etiologic agent of river blindness, have b

157 es against antigens prepared from Onchocerca volvulus third-stage larvae (L3), molting L3 (mL3), and

158 Mice immunized with irradiated Onchocerca volvulus third-stage larvae developed protective immunit

159 zymes that are likely to be essential for O. volvulus viability.

160 essed the relations between infection with O volvulus, visual acuity, and host mortality with data ob

161 ere present, the specificity for small-bowel volvulus was 100%.

162 Colonic volvulus was found to be the cause in 63,749 cases (1.90

163 rly exposure to or infection with Onchocerca volvulus was investigated in an autochthonous focus caus

164 Importantly, the chitinase OvCHT1 from O. volvulus was recently discovered, however, its exact rol

165 14 cases of malrotation with obstruction or volvulus were described (4.9%), of which 2 "symptomatic

166 Transition points associated with volvulus were less likely to be located more than 7 cm a

167 that infect the filarial nematode Onchocerca volvulus were previously found to have an essential role

168 s to adult and infective larval stages of O. volvulus which are age related are consistent with the a

169 h Ags from the parasitic helminth Onchocerca volvulus (which causes river blindness).

170 Extracts of Brugia malayi and Onchocerca volvulus, which contain Wolbachia, directly stimulated h

171 induced by the filarial nematode Onchocerca volvulus, which harbors endosymbiotic Wolbachia bacteria

172 m the filarial parasitic nematode Onchocerca volvulus, which is transmitted by the blackfly vector Si

173 TLR4-mutant mice were immunized against O. volvulus with irradiated third-stage larvae, and it was

174 ography (CT) in the diagnosis of small-bowel volvulus, with surgical findings as the reference standa

175 essed the effect of targeting the Onchocerca volvulus Wolbachia endosymbionts with doxycycline for th

176 he corneal stroma, and that TLR2 mediates O. volvulus/Wolbachia-induced neutrophil activation and dev

177 hypothesized that protective immunity to O. volvulus would not develop in C3H/HeJ mice which have a

178 With the genomes of L. loa, Onchocerca volvulus, Wuchereria bancrofti, and Brugia malayi availa

179 is being conducted in areas where Onchocerca volvulus, Wuchereria bancrofti, and L. loa are coendemic