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1 y in coming decades as conventional reserves wane.
2 al approaches that can detect early signs of wane.
3 raising concerns that vaccine efficacy might wane.
4 ressed until after the accelerated volcanism waned.
5 challenges, the vaccine's protecting effects waned.
6 ccination, antibody levels for all 3 viruses waned.
7 ixation as the early CTL response to this Ag waned.
8 bove baseline levels occurred as drug levels waned.
9  infection in individuals whose immunity has waned.
10 weeks, but infection emerged when NAb titers waned.
11 andemic, which began as the measles epidemic waned.
12 stitial CR concentration, [CR(o)], waxes and wanes.
13 lops and then delocalize as transformability wanes.
14 opment and the time at which B lymphopoiesis wanes.
15 ergo numerical contraction when inflammation wanes.
16 value of $80) and the rate at which efficacy wanes.
17 ugs, the use of alphaIIbbeta3 antagonists is waning.
18 t a time when acute inflammation is normally waning.
19 hallenge, while innate immune responses were waning.
20 g within an inflamed environment are weak or waning.
21 e of small dense LDL particles appears to be waning.
22  activation, which then occurs when IFN-I is waning.
23 ic that began in West Africa in late 2013 is waning.
24                 Intervention effects tend to wane 6-12 months after the cessation of treatment.
25 s after stopping the intervention the effect waned (7.3 m [95% CI -32.5 to 47.0]; p=0.50).
26 serotype is long-lived, heterotypic immunity wanes a few months after infection.
27                 Anti-circumsporozoite titres wane according to a biphasic exponential distribution.
28          There is accumulating literature on waning acellular pertussis vaccine-induced immunity, con
29 that catalyst reduction capability begins to wane after 5-6 years, 3 times faster than is observed in
30           Because immunity has been found to wane after vaccination, these booster doses can serve to
31 ion of vaccine-induced immunity; if immunity waned after 10 years, the cost of vaccination of preadol
32 ained T(IBAT), but the ability of the former waned after 2 h being significantly decreased by 18 h.
33                Opioid-use prevention effects waned after treatment discontinuation.
34 rovides significant protection, and does not wane against severe disease.
35 igns of viral protein expression appeared to wane, although residual viral RNA was detectable by in s
36      Acceptance of childhood vaccinations is waning, amplifying interest in developing and testing in
37 cific IgG antibodies are induced but rapidly wane and by 3 months post-infection the bats are seroneg
38 ognitive and memory function, in contrast to waned and abnormal neurogenesis, persistent inflammation
39          As banded iron formation deposition waned and continentally sourced Cu became more important
40 unstable and inactive as the damage response waned and MDM2 stabilized.
41           As the medicinal use of cobalt has waned and measures to reduce industrial exposure have be
42                                 PI mutations waned and replicative capacity and HIV RNA levels increa
43  neural responses to reward in these neurons waned and responses to cues that predicted reward emerge
44 jority of maternally acquired antibodies had waned and vaccine Env-specific immunoglobulin G (IgG) re
45 eir participation in the GC response rapidly wanes and they do not efficiently contribute to the memo
46 heir variable age at onset, their waxing and waning and the variability of body surface environment.
47                                              Waning anti-circumsporozoite antibody titres predict the
48 ccine are 97% effective against measles, but waning antibody immunity to measles and failure of the 2
49 months after the second vaccination, despite waning antibody levels.
50 as the result of weak, narrowly targeting or waning antiviral T-cell responses.
51               Postsynaptic responses wax and wane as presynaptic activity evolves.
52 nically represented by enfuvirtide), synergy waned as binding strength decreased until inhibitor comb
53  and ALX were high early in the response but waned as inflammation progressed.
54  early stage of infection, but this response wanes as a Th2-type response emerges during late stages
55  efficacy of peptide immunotherapy generally wanes as beta cell autoimmunity progresses and islet inf
56 companied by a marked IFN-beta response that wanes as SIV replication is controlled.
57 and 405 nm) and (iii) fluorescence intensity wanes as the emission wavelength increases.
58  thus graded synaptic transmission waxes and wanes as the neurons move from the depolarized to the in
59 ly when organic disease has been excluded is waning,as we now have evidence to support symptom-based
60 STAT1 phosphorylation and SOCS1 augmentation waned at 24 h, while STAT3 activity increased.
61 tage over clade NI-1 early in infection that wanes at later time points.
62           Two Apa-boosters markedly improved waning BCG-immunity and significantly reduced Mycobacter
63 ility, the passenger lymphocyte syndrome, is waning because anti-B-cell immunosuppressive therapy is
64                     Moreover, this phenotype wanes before the onset of overt T1D and is dispensable f
65 nge on FAQOL; however, the effect appears to wane between 2 and 6 months postchallenge in those confi
66 pathologies in which painful memories do not wane but are evoked time and again (e.g., post-traumatic
67 ccine; (2) pertussis antibody levels rapidly wane but promptly increase after vaccination; (3) whole-
68 to 4 weeks hematopoiesis in treated cultures wanes but if catalase is removed, hematopoiesis resumes.
69 ear; however, this effect of IVIG appears to wane by 2 years.
70 ivities are rapidly induced, within 3 d, and wane by 5 d following infection.
71 d by two efficient nonlive vaccines began to wane by 6 months.
72 s occurred at 3-12 hours after injection and waned by 24 hours after injection which tracked the drug
73  ventricular tachyarrhythmias and waxing and waning cardiomyopathy.
74 t's dorsal ganglia and can reactivate due to waning cell-mediated immunity, causing HZ.
75 ion of w increases the critical fraction for waning commitment and decrease this fraction for increas
76    Increasing w lowers critical fraction for waning commitment but increases this fraction for increa
77 going neuronal activity in the CNS waxes and wanes continuously across widespread spatial and tempora
78  overcoming the natural tendency for rapidly waning coronavirus immunity.
79 ures include premonitory urges, a waxing and waning course, and to a much lesser degree, coprolalia.
80                                As glaciation waned, debris-covered glaciers ceased flowing, accumulat
81 ure utility for pharmacogenetics will wax or wane depending on the nature of available drugs and ther
82  infections, virus-specific T-cell responses wane due to the antigen-specific deletion or functional
83  care time available for trauma/intensivists wanes due to increased surgical and non-critical care pa
84                 Protection against pertussis waned during the 5 years after the fifth dose of DTaP.
85 If the breadth of the immune response slowly wanes during disease progression, the model predicts an
86 eral, media interest and reporting peaks and wanes during the course of an outbreak.
87                                         This waning effectiveness supports the need for annual revacc
88 data indicate that, rather than boosting the waning efficacy of BCG, a vaccination schedule involving
89 sential to identify any signals of potential waning efficacy or type-replacement.
90 boptimal Ag found in lymphoid tissues at the waning end of the effector phase and microbial clearance
91 MB-435 tumors infected with Ad-HA-SSTR2 from waning expression at the later time point (P < .05).
92  levels of resistance, though protection may wane faster against more resistant mosquito populations
93 enesis model where cross-reactive antibodies wane from higher-titer, protective levels to lower-titer
94 gammac.b were first observed from 8 hpf, but waned from 16 hpf before reaching maximal expression at
95 h, w, defining their willingness to lose (in waning), gain (for increasing) or both (in variable) com
96 out vaccination safety further contribute to waning herd immunity in developed countries, resulting i
97 dependent of autocrine SHH, but the TAC pool wanes if they can't produce SHH.
98 hat in 7CH rats, tonic adenosine release has waned; (iii) that in 1-7CH rats, adenosine released by a
99                                   To mimic a waning immune response, and to assess priming for ERD un
100  model for wild poliovirus that incorporates waning immunity (which affects both infection risk and t
101 rgences of the epidemic, we go on to include waning immunity and a mechanism explicitly accounting fo
102 rces (instantaneous rates) of infection, but waning immunity and clinical consequences that depend on
103  pertussis resurgence has been attributed to waning immunity and other factors, vaccine refusal was s
104 te history of vaccination also suggests that waning immunity could have contributed to susceptibility
105 oupled with exposure to infected caregivers, waning immunity despite complete vaccination, inferior l
106                      Our results demonstrate waning immunity following vaccination with either Tdap b
107 ges in sustaining high vaccination coverage, waning immunity in HIV-1-infected children, and clusteri
108         Imported food products combined with waning immunity in some adult populations might make thi
109 any developed countries has been linked with waning immunity induced after immunization with acellula
110       In countries using acellular vaccines, waning immunity is at least part of the problem.
111 lusters of nonmedical vaccine exemptions and waning immunity may have been factors contributing to co
112 he role of nonmedical vaccine exemptions and waning immunity may have had on the resurgence of pertus
113                   Raising concerns about the waning immunity of cohorts receiving hepatitis B virus (
114 oncerns remain about lower effectiveness and waning immunity of rotavirus vaccines in resource-poor p
115                                              Waning immunity or secondary vaccine failure (SVF) has b
116 ine improved mumps outbreak control and that waning immunity probably contributed to propagation of t
117 rmation for both primary vaccine failure and waning immunity provide essential information for our pr
118                                  Analysis of waning immunity rates and oral polio vaccine transmissib
119 vaccine transmissibility reveals that higher waning immunity rates make eradication more difficult be
120 sibility, clearance of initial infection and waning immunity were derived in a Bayesian framework by
121 c drift phenomenologically with continuously waning immunity, and the second epochal evolution model
122 porating high asymptomatic ratio and rapidly waning immunity, with infection both from human and envi
123 d dose for outbreak control and assessed for waning immunity.
124 in highly vaccinated populations, indicating waning immunity.
125 ren ages 10 to 14 years old, consistent with waning immunity.
126 ause of impaired initial vaccine response or waning immunity.
127                       Although VE appears to wane in children aged >/=1 year, it still provides signi
128 gaelectron volt (MeV) electrons that wax and wane in intensity on time scales ranging from hours to d
129 niches, decline in numbers with age, wax and wane in numbers with injury responses, and are proposed
130 density of proline label would often wax and wane in opposing contrast to these local fluctuations in
131 o response rates; in conditions that wax and wane in severity, have spontaneous remissions, or have a
132 essive early potency of the CTL response may wane in the transition to the chronic stage of the infec
133 memory CD8(+) T cells declined as protection waned in mice treated with primaquine, a drug that inter
134     In adult brain, reporter gene expression waned in most areas but remained in vascular endothelia
135 c CD4+ and CD8+ T cells expressing cytokines waned in peripheral blood lymphocytes by day 84, but CD8
136 died a decade ago, interest in this area has waned in recent years.
137 ction demonstrated lytic potential, but this waned in the chronic stage.
138 funding and promotion of family planning has waned in the past decade.
139 h the end of 2009 when pandemic activity had waned in the United States.
140 emoval of a hypoxic dilator stimulus that is waning in 7CH rats.
141                   Our analysis accounted for waning in antibody titers over time, and could be partic
142                                A progressive waning in Foxp3(+) regulatory T cell (Treg) functions is
143 f enhancing specific T-cell responses during waning in the lung and spleen.
144 ulsed daily manner, starting after dusk, and waning in the morning, as photosynthesis resumed.
145  that biomedical research as a profession is waning in the United States (see "Rescuing US biomedical
146                                With interest waning in the use of cyclooxygenase-2 (COX-2) inhibitors
147 stelae strain, a finding consistent with its waning infection status, whereas lesions characteristic
148                      Furthermore, imperfect, waning intestinal immunity among older children and adul
149  cholecystitis subsequently developed waxing waning jaundice and recurrent episodes of upper gastroin
150                  This asymmetric deformation waned just before the Hawaiian-Emperor bend developed, o
151                     When utility in the task wanes, LC neurons exhibit a tonic activity mode, associa
152                     When utility in the task wanes, LC neurons exhibit a tonic activity mode, associa
153 , these first T cell responses often rapidly waned, leaving or being succeeded by T cell responses to
154 n of large floods after A.D. 1200, driven by waning midcontinental aridity, marks the onset of sociop
155               Vaccine-induced antibodies may wane more quickly in persons living with human immunodef
156 nses against tetanus and diphtheria antigens waned more quickly, with estimated half-lives of 11 year
157 s and transmission intensities, and efficacy wanes more rapidly at higher transmission intensity.
158 at the immunity derived from mild infections wanes much more rapidly than earlier analyses have indic
159 We infer the viral transmissibility, rate of waning natural immunity and rates of progression and cle
160                                      Greatly waned neurogenesis, diminished microvasculature, astrocy
161 n is equilibrium: synaptic strengths wax and wane, neuronal firing rates adjust up and down, and neur
162                                   Waxing and waning of a global authigenic carbonate sink helps to ex
163 of OP development, which featured waxing and waning of amplitudes, was observed and might have been c
164                                        Rapid waning of anti-polysaccharide bactericidal Ab and vaccin
165 dy responses to measles vaccine, their rapid waning of antibody suggests that measles vaccination cam
166 um ice volume estimates show that waxing and waning of at least approximately 85 to 110% of the volum
167                                              Waning of both the concentration as well as the avidity
168 extremes, changing inter-annual variability, waning of dominant inter-decadal quasi-periodic dynamics
169                                 However, the waning of effects over follow-up, although moderated by
170 s association is consistent with intraseason waning of host immunity, but bias or residual confoundin
171                                   Unexpected waning of immunity after pertussis vaccination is now we
172                                     However, waning of immunity from acellular vaccines may be drivin
173                                           No waning of immunity was evident during the first 4 years
174                                       During waning of insulin effect, GLUT4 was re-internalized to b
175 a century of investigation with a waxing and waning of interest, the role of sleep in memory processi
176 track pattern associated with the waxing and waning of Late-Pleistocene Northern Hemisphere ice sheet
177 re is a gap in neonatal immunity between the waning of maternal protection and routine infant immuniz
178 by MCh was maintained for 30 minutes despite waning of MCh concentration over that period, measured a
179 the contraction phase or protect against the waning of memory T cell numbers at later times after inf
180 rge of magma from deep in the crust and with waning of overpressure in the magma reservoir.
181 tion of smallpox vaccination and concomitant waning of population-level immunity.
182 IV vaccine trial, which demonstrated a rapid waning of protective immunity with time, have underscore
183 th platelet recovery with inversely parallel waning of serum-induced heparin-independent serotonin re
184                         A general waxing and waning of staining intensity were observed over this dev
185 2a (eIF2a) restores protein synthesis at the waning of stress responses and requires a PP1 catalytic
186 ecific effects such as the normal waxing and waning of symptoms over time and the quality of the doct
187 was slight but not statistically significant waning of the efficacy of BCG vaccination over time, gre
188  disease symptoms often appear subsequent to waning of the Th1-like immune response.
189 amics of cancer evolution and the waxing and waning of tumor subclones over time in advanced metastat
190  cohort effects, and potential within-season waning of vaccine protection.
191 (II) frequent primary vaccine failure, (III) waning of vaccine-derived protection, and (IV) vaccine "
192 mps in highly vaccinated populations suggest waning of vaccine-induced immunity and primary vaccine f
193 istent with long-lasting BCG protection, but waning of VE with time.
194 and graded components, both of which wax and wane on a cycle-by-cycle basis.
195 updates the literature that seems to wax and wane on the importance of specific immunity to malignant
196        Responses remained high on day 60 but waned on days 180 and 360.
197 e of Hib antibodies suggests that protection wanes only after the age at greatest risk of disease.
198 hat influenza vaccine effectiveness (VE) may wane over the course of an influenza season, leading to
199 hat influenza vaccine effectiveness (VE) may wane over the course of an influenza season, leading to
200  the incremental yield of ICF is expected to wane over time as the pool of undiagnosed cases is deple
201               Mucosal immunity is thought to wane over time but the rate of loss of protection has no
202 because the benefits of former INT treatment wane over time if A1C levels rise.
203 us type 1 (HIV-1) gp41 antibodies, which can wane over time in some HIV-1-infected populations, resul
204  causes HIV-specific CD8 T cell responses to wane over time.
205 its of pulmonary rehabilitation (PR) tend to wane over time.
206 suggesting that the effects of interventions wane over time.
207 logic outcomes at 6 months, but the benefits wane over time.
208 ntly, mouse heterosubtypic immunity that had waned over several months could be enhanced by injecting
209                           Because protection waned over several months, we boosted ChAd3 with modifie
210 d 6-10 weeks after vaccination and gradually waned over the first year of life.
211 carnitine in skeletal muscle appears to have waned over the past 25 years.
212                             Vaccine efficacy waned over time (P=0.006 for the interaction between vac
213 mory CD8(+) T cells in double-deficient mice waned over time and were not protective against rechalle
214  gammaHV68 latency in CD40-deficient B cells waned over time in chimeric mice.
215 lly, their estimated effects were modest and waned over time.
216 lly, their estimated effects were modest and waned over time.
217 y activated viral infection, but this effect waned over time.
218 epeated exposure to inhaled Ag, inflammation wanes over time and thus limits the study of chronic air
219                        However, its efficacy wanes over time as motor complications develop.
220 ins unclear whether vaccine-induced immunity wanes over time, a condition that may result in increase
221 lingness to engage in safe behavior waxes or wanes over time, depending on the severity of an epidemi
222 timulate immunity in their hosts, which then wanes over time.
223 b varies widely among patients and typically wanes over time.
224 e are achieved routinely, long-term function wanes over time.
225 ated reexposures; 2) partial protection that wanes over time; or 3) full but temporary immunity again
226 itially caused severe disease that gradually waned (P < 0.02).
227  disease in question and the acquisition and waning patterns of immunity.
228 ivated inward current (IMI), which waxes and wanes periodically due to phasic feedback inhibition of
229 ntibodies that decay or active immunity that wanes, permitting re-infection.
230              To dissect the contributions of waning pertussis immunity and repeat infections to pertu
231 action of an adaptive immune response in its waning phases.
232  changes considerably between the waxing and waning portions of the eruption.
233 ned to baseline and the clinical improvement waned, possibly due to the patient's complex epilepsy.
234 nal blips of plasma viraemia that ultimately waned; predominantly undetectable cell-associated viral
235  against RSV infection and pathogenesis, and waning protection correlated with reduced CD8(+) T cell
236 veloping countries, and evaluations indicate waning protection from rotavirus immunization in the sec
237 incorporate age structures and progressively waning protection over time.
238 nly weak antibody responses and very modest, waning protection.
239 TaP) coverage, indicating the possibility of waning protection.
240 keys, but these responses were transient and waned quickly.
241 g those initiating PrEP with acute infection waned rapidly after drug discontinuation.
242        Peak titers were higher in Vax003 and waned rapidly in both trials.
243                       Enfuvirtide resistance waned rapidly in the absence of drug pressure and was no
244 sfer occurred, but seroprotection in infants waned rapidly.
245 major challenges: coronavirus immunity often wanes rapidly, individuals needing to be protected inclu
246 h we found that adaptive immunity to anthrax wanes rapidly, subsequent and frequent sublethal B. anth
247 tograph; however, this newly created empathy waned rather quickly.
248 ections detected by HPV and cytology wax and wane relative to each other.
249 ion, with a temporal decline in T-bet in the waning response.
250 gen removal, the antigen-specific population waned, resulting in development of a self-specific memor
251 ond half (P=.02 for interaction), suggesting waning risk after cessation of shift work.
252 patient over years, and prolonged waxing and waning seropositivity in some subjects, raises the possi
253 fective antiretroviral therapy, demonstrated waning serum anti-gp41 titers and Western blot band inte
254  intestinal mucosal immunity that appears to wane significantly within a year of vaccination.
255  after parenteral or mucosal BCG-priming but waned significantly by 78 weeks.
256 active epochs up to 1-1.5 sec and introduced waning spindle sequences.
257 arge igneous province (LIP) and represents a waning stage in the emplacement of several temporally di
258  reservoir during ocean deoxygenation in the waning stages of the positive carbon isotope excursion.
259 25 weeks after immunization, antibody levels waned substantially by 59 weeks.
260 wever, once anti-CCR5 antibody responses had waned, the 3 animals became infected after intravaginal
261                       As the Lomagundi event waned, the oxygen source became a net oxygen sink as Lom
262 st-injury in the wild-type mice and began to wane thereafter; however, in Timp3(-/-) mice, inflammati
263 suppression of alloresponses in vitro, which waned thereafter to the levels mediated by naive CD25(+)
264                Our findings demonstrate that waning thymic output results in a decrease in CD45RA+CD3
265 ions that were predominant at seroconversion waned to background levels within 24 weeks after discont
266 wever, by postnatal day 19, immunoreactivity waned to become restricted to crypts and concentrated at
267 eficiency virus (HIV) acquisition at 1 year, waning to 31.2% after 3.5 years.
268           The enhanced cellular alloresponse waned toward prevaccine levels by week 12.
269 and SVR were maintained, but RF, HR and MSNA waned towards baselines from the second to the tenth min
270 cancer reached a peak in the 1990s, and then waned until the availability in the past 5 years of mono
271                                        Given waning vaccine efficacy over time, this secondary analys
272 ed awareness, improved diagnostic means, and waning vaccine-induced immunity among adolescents and ad
273 ection from both primary vaccine failure and waning vaccine-induced immunity.
274 s is likely due to increased recognition and waning vaccine-induced immunity.
275                    Statistically significant waning was detected for IIV (P = .03) but not LAIV (P =
276 d avoiding a resurgence as treatment options wane will require careful attention to all components of
277 he latter are prominent in young animals and wane with age.
278  thrombotic risk with IBD appears to wax and wane with disease severity.
279 eobacteria, the populations of which wax and wane with that of E. huxleyi.
280                                     The risk waned with time after discontinuation.
281 k seen in interim analysis was confirmed but waned with time from vaccination.
282 ved genomic sequence variants that waxed and waned with time in progressive tumors, suggesting the pr
283                                     The risk waned with time since last prescription redemption.
284 ng uncircumcised and/or Ad5-seropositive men waned with time since vaccination.
285 dence of complete short-term protection that waned with time, and immune response patterns associated
286                     Novy's curiosity had not waned with time.
287 n in the newborn midbrain and brainstem that wanes with age and maximal expression in the cerebellar
288 ls and adiponectin-induced PEPITEM secretion wanes with age, implying immune senescence of the pathwa
289             Here, we explore why hair growth wanes with age.
290 y affected, in part because vaccine efficacy wanes with age.
291                                This reliance wanes with increasing age, in tandem with age-related in
292 al poliovirus vaccine (OPV) is imperfect and wanes with time, permitting transmission of infection by
293 the vaccinee, and the duration of this boost wanes with time.
294 nd is only marginally attributable to immune waning with age.
295 I-/- mice, and influenza-specific IgG titers wane within 60 days postinfection.
296    HCV-specific T-cell responses in EU cases wane within months of cessation of injection drug use.
297                  Latent infection appears to wane within the transitional memory compartment in patie
298 ive attenuated zoster vaccine Zostavax (ZVL) wanes within 3-7 years.
299 ent ischemic injury, although the protection wanes within days.
300 ously thought, with some symptoms waxing and waning within symptom dimensions and rarely involving sh

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