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1                    The primary end point of CKD progression was a composite of 50% eGFR loss, eGFR less than 10 mL/min/1.
2    The primary outcome was any vascular complication, which was a composite of access-site bleeding, access-site hematoma
3                              The primary efficacy end point was a composite of adjudicated cardiovascular death, myocardi
4                                         The primary outcome was a composite of adverse perinatal outcomes, which included
5                                        The primary endpoint was a composite of all-cause death, AVR, and HF hospitalizati
6                                       The primary end point was a composite of all-cause death, myocardial infarction, or
7 t (major adverse cardiac or cerebrovascular events [MACCE]) was a composite of all-cause death, nonfatal myocardial infar
8                                The primary efficacy outcome was a composite of asymptomatic proximal deep-vein thrombosis
9                                           Primary end point was a composite of cardiac death and nonfatal myocardial infa
10                                 The primary safety endpoint was a composite of cardiac death, myocardial infarction, or s
11                                       The primary end point was a composite of cardiovascular death, myocardial infarctio
12                                 The key secondary end point was a composite of cardiovascular death, myocardial infarctio
13                                        The primary endpoint was a composite of cardiovascular death, myocardial infarctio
14                                  The key secondary endpoint was a composite of cardiovascular death, myocardial infarctio
15                              The primary efficacy end point was a composite of cardiovascular death, myocardial infarctio
16 utcome (the time to first major cardiovascular event, which was a composite of cardiovascular death, non-fatal myocardial
17                                       The primary end point was a composite of cardiovascular death, nonfatal myocardial
18                                         The primary outcome was a composite of cardiovascular disease events.
19 n and the 24-month incidence of new brain infarction, which was a composite of clinical ischemic stroke or silent brain i
20                                         The primary outcome was a composite of death and thrombotic complications (nonfat
21                                       The primary end point was a composite of death from any cause or disabling stroke a
22                                       The primary end point was a composite of death from any cause, myocardial infarctio
23                                       The primary end point was a composite of death from any cause, nonfatal myocardial
24                                         The primary outcome was a composite of death from cardiovascular causes, nonfatal
25                                         The primary outcome was a composite of death or neurodevelopmental impairment (ND
26                                       The primary end point was a composite of death or severe renal failure leading to r
27                              The primary efficacy end point was a composite of death, myocardial infarction, ischemia-dri
28                                       The primary end point was a composite of death, stroke, or myocardial infarction du
29                                       The primary end point was a composite of death, the need for dialysis, or a persist
30                                The primary safety end point was a composite of freedom from device- and procedure-related
31                                         The primary outcome was a composite of long-term CV events or death, which was as
32                                         The primary outcome was a composite of major adverse kidney events (persistent re
33                                         The primary outcome was a composite of major postoperative respiratory complicati
34                                         The primary outcome was a composite of MI and stroke events based on primary disc
35                                 The primary outcome measure was a composite of myocardial infarction and target vessel fa
36                                        The primary endpoint was a composite of myocardial infarction, stroke, and death f
37                                 The secondary renal outcome was a composite of new-onset persistent macroalbuminuria, per
38                                         The primary outcome was a composite of nonfatal acute myocardial infarction, nonf
39                                       Functional impairment was a composite of poor academic performance (defined as at l
40                             The primary outcome of interest was a composite of postoperative major complications.
41 ed as vessel-oriented clinical end point (VOCE) at 2 years, was a composite of prospectively adjudicated cardiac death, v
42                              The primary efficacy end point was a composite of recurrent nonfatal ischemic stroke, fatal
43                                         The primary outcome was a composite of recurrent venous thromboembolism or major
44                                         The primary outcome was a composite of repeat ED visit, hospital admission, or de
45 p1 or placebo (modified intention-to-treat population), and was a composite of stable or increased lean body mass and sta
46                                         The primary outcome was a composite of stent-related complications defined as pai
47                                       The primary end point was a composite of survival free of disabling stroke (with di
48                                The primary efficacy outcome was a composite of symptomatic deep-vein thrombosis or pulmon
49                                         The primary outcome was a composite of systemic inflammatory response syndrome an
50                                         The primary outcome was a composite of treatment failure defined by any of the fo

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