ライフサイエンスコーパス: wasting disease

1 ed by LCMV infection are sufficient to cause wasting disease.

2 ts of this antiviral immune response mediate wasting disease.

3 HV68), then succumb with symptoms of chronic wasting disease.

4 e virus leads to a severe weight loss called wasting disease.

5 ced wasting and that IL-6 contributes to the wasting disease.

6 -68), then develop symptoms of a progressive wasting disease.

7 Triple(lo)CD4(+) T cells induced colitis and wasting disease.

8 e muscular dystrophy (DMD), a genetic muscle-wasting disease.

9 reutzfeldt-Jakob disease, and cervid chronic wasting disease.

10 uces IRIS pathology, even after the onset of wasting disease.

11 1A2 cause complete loss of function and salt-wasting disease.

12 bovine spongiform encephalopathy and chronic wasting disease.

13 ity in transgenic mice infected with chronic wasting disease.

14 Duchenne muscular dystrophy, a lethal muscle wasting disease.

15 diagnosis of Bartter syndrome, a renal salt-wasting disease.

16 ogical properties for use in treating muscle wasting diseases.

17 such as obesity, type II diabetes or chronic wasting diseases.

18 herited, noninflammatory, progressive muscle wasting diseases.

19 ons in hENaC result in hypertensive and salt-wasting diseases.

20 egenerative response and ameliorating muscle-wasting diseases.

21 bling future cell-based therapies for muscle-wasting diseases.

22 llowing evaluation of prions causing chronic wasting disease, a naturally occurring transmissible spo

23 (WT) mice developed a CD4(+) T-cell-mediated wasting disease after intracranial infection with LCMV.

24 e challenged domestic swine with the chronic wasting disease agent by inoculation directly into the b

25 he adult tgepsilon26 mouse results in severe wasting disease and colitis.

26 rican continent, often resulting in a severe wasting disease and death.

27 is the causative agent of both a veterinary wasting disease and human African trypanosomiasis, or sl

28 stration of anti-CD3 protected the mice from wasting disease and intestinal inflammation.

29 ns, the infectious agent of scrapie, chronic wasting disease and other transmissible spongiform encep

30 reas interleukin-12 p35 secretion controlled wasting disease and serum cytokine production but not mu

31 at TNF-alpha is not involved in LCMV-induced wasting disease and show that IFN-gamma contributes to t

32 educes C-reactive protein levels, alleviates wasting disease, and extends host survival during experi

33 ie, BSE, mouse-adapted scrapie, deer chronic wasting disease, and hamster-adapted scrapie prions.

34 trophy (DMD) is a lethal, progressive muscle wasting disease caused by a loss of sarcolemmal bound dy

35 dystrophy (DMD) is a lethal, X-linked muscle-wasting disease caused by lack of the cytoskeletal prote

36 ular dystrophy (DMD) is a devastating muscle wasting disease caused by mutations in dystrophin.

37 phy (DMD) is a severe and progressive muscle-wasting disease caused by mutations in the dystrophin ge

38 trophy (DMD) is an incurable X-linked muscle-wasting disease caused by mutations in the dystrophin ge

39 trophy (DMD) is an X-linked recessive muscle wasting disease caused by the absence of a muscle cytosk

40 g born to muntjac dams infected with chronic wasting disease (CWD) (1).

41 ed conversion (RT-QuIC) and compared chronic wasting disease (CWD) and classical bovine spongiform en

42 in Wisconsin known to be affected by chronic wasting disease (CWD) and from 210 free-ranging white-ta

43 is a reservoir for prions that cause chronic wasting disease (CWD) and influences the risk of transmi

44 cervidized mice to determine (i) if chronic wasting disease (CWD) blood infectivity is associated wi

45 Here we compare the incidence of chronic wasting disease (CWD) in captive mule deer (Odocoileus h

46 Chronic wasting disease (CWD) in cervids and bovine spongiform e

47 In chronic wasting disease (CWD) in cervids and in scrapie in sheep

48 transmission is a signature trait of chronic wasting disease (CWD) in cervids.

49 The emergence of chronic wasting disease (CWD) in deer and elk in an increasingly

50 oduce a transgenic system simulating chronic wasting disease (CWD) in deer and elk.

51 t factors on phenotypic diversity of chronic wasting disease (CWD) in different host species that exp

52 Chronic wasting disease (CWD) is a fatal prion disease in deer a

53 Chronic wasting disease (CWD) is a fatal prion disease of North

54 Chronic wasting disease (CWD) is a fatal spongiform encephalopat

55 Chronic wasting disease (CWD) is a fatal, endemic prion disease

56 Chronic wasting disease (CWD) is a highly contagious always fata

57 Chronic wasting disease (CWD) is a naturally occurring, fatal ne

58 Chronic wasting disease (CWD) is a neurodegenerative prion disea

59 Chronic wasting disease (CWD) is a prion disease of cervids that

60 Chronic wasting disease (CWD) is a prion disorder of increasing

61 Chronic wasting disease (CWD) is a rapidly spreading prion disor

62 Chronic wasting disease (CWD) is a transmissible spongiform ence

63 Chronic wasting disease (CWD) is a transmissible spongiform ence

64 to precede neuroinvasion.IMPORTANCE Chronic wasting disease (CWD) is a universally fatal transmissib

65 Chronic wasting disease (CWD) is an emergent, rapidly spreading

66 Chronic wasting disease (CWD) is an emerging and uniformly fatal

67 Chronic wasting disease (CWD) is an emerging prion disease of ca

68 Chronic wasting disease (CWD) is an emerging prion disease of de

69 Chronic wasting disease (CWD) is an emerging transmissible spong

70 which facilitate the transmission of chronic wasting disease (CWD) of cervids and allow prion strain

71 Chronic wasting disease (CWD) of cervids is associated with conv

72 mission of prion diseases, including chronic wasting disease (CWD) of cervids, is the potential prese

73 rodegenerative diseases that include chronic wasting disease (CWD) of cervids.

74 prion diseases-scrapie of sheep and chronic wasting disease (CWD) of several species in the deer fam

75 smission of infectious diseases such chronic wasting disease (CWD) or bovine tuberculosis.

76 While chronic wasting disease (CWD) prion transmission, entry, and tra

77 In nature, cervids are infected with chronic wasting disease (CWD) prions by oral and nasal mucosal e

78 ative errors to test deer saliva for chronic wasting disease (CWD) prions.

79 Traditional diagnostic detection of chronic wasting disease (CWD) relies on immunodetection of misfo

80 While the facile transmission of chronic wasting disease (CWD) remains incompletely elucidated, s

81 e in the transmission of scrapie and chronic wasting disease (CWD) via the environment.

82 ly, the frequency of strains causing chronic wasting disease (CWD), a burgeoning prion epidemic of ce

83 , a species naturally susceptible to chronic wasting disease (CWD), a burgeoning, contagious epidemic

84 lations that have been infected with chronic wasting disease (CWD), a contagious, fatal prion disease

85 omotes propagation of prions causing chronic wasting disease (CWD), a fatal, transmissible, neurodege

86 Chronic wasting disease (CWD), a prion disease affecting free-ra

87 Chronic wasting disease (CWD), a transmissible prion disease tha

88 Chronic wasting disease (CWD), a transmissible spongiform enceph

89 Chronic wasting disease (CWD), a transmissible spongiform enceph

90 Chronic wasting disease (CWD), a transmissible spongiform enceph

91 Chronic wasting disease (CWD), the only known prion disease ende

92 c mice has induced susceptibility to chronic wasting disease (CWD), the prion disease of cervids.

93 including those in areas affected by chronic wasting disease (CWD), we evaluated the susceptibility o

94 rion protein glycoform patterns from chronic wasting disease (CWD)-affected deer and elk, scrapie-aff

95 e and Tg(BoPrP) mice as well as from chronic wasting disease (CWD)-infected deer and elk.

96 e, we removed the lipid content from chronic wasting disease (CWD)-infected white-tailed deer brain h

97 er, a species susceptible to the TSE chronic wasting disease (CWD).

98 cted white-tailed deer with clinical chronic wasting disease (CWD).

99 ertain rodents may be susceptible to chronic wasting disease (CWD).

100 rapie in sheep or prions that caused chronic wasting disease (CWD; hereafter "CWD prions") in deer, u

101 fective treatment for the devastating muscle-wasting disease Duchenne muscular dystrophy (DMD).

102 The X-linked muscle wasting disease Duchenne muscular dystrophy is caused by

103 An accelerated wasting disease elicited by T cells deficient in IL-17A

104 eficient beta 2m- Jpr mice develop a similar wasting disease following i.c. infection.

105 rophy (BMD) is a progressive X-linked muscle wasting disease for which there is no treatment.

106 soma brucei brucei, the causative agent of a wasting disease in cattle.

107 form encephalopathy (BSE) in cattle, chronic wasting disease in deer and elk, and Kuru disease, Creut

108 n in vitro, and these cells provoke a lethal wasting disease in lymphopenic mice despite the presence

109 GVHD-induced wasting disease in MHC class II-disparate recipients of

110 GVHD induced wasting disease in recipients of B6.IL-12R(-/-) CD4(+) s

111 st, MyD88 knockout (KO) mice did not develop wasting disease in response to the same infection.

112 ographic spread in the prevalence of chronic wasting disease in white-tailed deer (Odocoileus virgini

113 nflammatory cytokines in the pathogenesis of wasting disease induced by LCMV infection.

114 Chronic wasting disease is a fatal, neurological disease caused

115 A potential mediator of this chronic wasting disease is tumor necrosis factor (TNF)-alpha, wh

116 crapie-derived prion strain ME7, and chronic wasting disease, it was ineffective in slowing propagati

117 lar dystrophy is a rare, progressive, muscle-wasting disease leading to severe disability and prematu

118 ronic renal failure caused by polyuric, salt-wasting diseases may be hampered if ongoing sodium and w

119 , transmissible mink encephalopathy, chronic wasting disease of cervids, and bovine spongiform enceph

120 phy (DMD) is the most common, lethal, muscle-wasting disease of childhood.

121 seases with high prevalence, notably Chronic Wasting Disease of deer and elk and atypical/Nor98 scrap

122 CD40-induced colitis, but not wasting disease or serum proinflammatory cytokine produc

123 istics upon passage to cats but that chronic wasting disease prions adapt to the cat and are distingu

124 Additionally, we showed that chronic wasting disease prions are effective at seeding the conv

125 trains of mouse prions and with deer chronic wasting disease prions.

126 ransporter NBCe1, results in the bicarbonate-wasting disease proximal renal tubular acidosis (pRTA).

127 tions to these subunits can lead to the salt wasting disease pseudohypoaldosteronism type I, associat

128 l defective in gating that leads to the salt-wasting disease pseudohypoaldosteronism type I, was resc

129 receptor elicited an accelerated, aggressive wasting disease relative to that elicited by wild-type T

130 ephalopathy (TSE) diseases including chronic wasting disease, scrapie, and bovine spongiform encephal

131 Ovine scrapie and cervine chronic wasting disease show considerable horizontal transmissio

132 is therefore a potential therapy for muscle wasting diseases, some of which are associated with a de

133 an extensive outbreak of sea-star (asteroid) wasting disease (SSWD).

134 ic intestinal infection leading to a chronic wasting disease termed paratuberculosis or Johne's disea

135 trophy (DMD) is a severe, progressive muscle-wasting disease that causes cardiac or respiratory failu

136 IL-12-deficient mice developed a progressive wasting disease that correlated with increased hepatic f

137 dystrophy type 1A (MDC1A) is a lethal muscle-wasting disease that is caused by mutations in the LAMA2

138 Muscular dystrophy is a progressive muscle wasting disease that is thought to be initiated by unreg

139 cally heterogeneous group of skeletal muscle-wasting diseases that differ widely in their frequency a

140 amined the role of cytokines in LCMV-induced wasting disease using mice lacking specific cytokines or

141 ular dystrophy (DMD) is a progressive muscle wasting disease usually resulting in death of patients b

142 T cells from MyD88(-/-) mice did not induce wasting disease when transferred into RAG1(-/-) recipien

143 Surviving animals suffered from a wasting disease, which usually resulted in death between

144 type 1A (MDC1A) is a severe and fatal muscle-wasting disease with no cure.

145 dystrophies are broadly classified as muscle wasting diseases with myofiber dropout due to cellular n

146 PORTANCE The facile dissemination of chronic wasting disease within captive and free-range cervid pop