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1                       To address this issue, we carried out 60x whole-genome sequencing of 26 metasta
2                To evaluate this possibility, we carried out a behavioural study on the performance of
3                                      Lastly, we carried out a bioinformatics analysis and found 51 ex
4 shell matrix proteomes from various species, we carried out a BLASTp bioinformatics analysis using th
5                                              We carried out a case-control genome-wide association st
6                                              We carried out a case-only analysis to explore whether p
7     To test the functionality of our device, we carried out a cell viability assay with adherent and
8 ify small molecule inhibitors of EBOV entry, we carried out a cell-based high-throughput screening us
9                                        Here, we carried out a combination of multiplex PCR, amplicon
10  development of the human B cell repertoire, we carried out a comprehensive analysis of productive an
11     To define the genetic complexity of OME, we carried out a comprehensive forward genetic screen.
12                                              We carried out a comprehensive functional analysis of th
13         To determine which model is correct, we carried out a comprehensive mode-of-action study usin
14                     To test this hypothesis, we carried out a comprehensive motif analysis on the pro
15                                              We carried out a comprehensive proteomic analysis of hum
16 rm the future development of such molecules, we carried out a comprehensive structural analysis of th
17 creasing knowledge about the viral proteome, we carried out a comprehensive yeast two-hybrid analysis
18                                              We carried out a convergent validation process using cov
19                                              We carried out a cross-sectional study of obese patients
20                                         Here we carried out a deep RNA-seq analysis of the BA4 (Brodm
21                   To study these mechanisms, we carried out a deep sequencing analysis of the transcr
22                                   Therefore, we carried out a detailed analysis of phycobilisome dyna
23 ng this spatial control of lrgAB expression, we carried out a detailed analysis of the LytSR two-comp
24 tional design tools, and mutagenesis assays, we carried out a detailed and systematic investigation o
25 ion suitable for studying such interactions, we carried out a detailed biophysical analysis of zipper
26                                              We carried out a detailed characterization of the Esrp1
27  implemented a genome-wide approach in which we carried out a drop-out shRNA screen using a whole gen
28                                              We carried out a first so far analysis of associations b
29 ntify SWI/SNF targets regulating senescence, we carried out a focused shRNA screen.
30                            For this purpose, we carried out a genetic analysis for En and TE in grape
31                                        Thus, we carried out a genetic association study on the sample
32         To identify new susceptibility loci, we carried out a genetic study of migraine on 59,674 aff
33                               In this study, we carried out a genome-wide analysis of mRNAs encoded b
34                                              We carried out a genome-wide association meta-analysis o
35 t confer risk of osteoarthritis of the hand, we carried out a genome-wide association study (GWAS) in
36  for PsA and cutaneous-only psoriasis (PsC), we carried out a genome-wide association study (GWAS) of
37        In the UK Biobank sample (N=108 976), we carried out a genome-wide association study (GWAS) of
38           To identify additional novel loci, we carried out a genome-wide association study in two po
39 estigate differences between sexual systems, we carried out a genome-wide association study using res
40 during growth under glucose supplementation, we carried out a genome-wide screen for genes involved i
41                                        Here, we carried out a genome-wide screen to identify Rab path
42                                              We carried out a genome-wide transcriptome analysis to i
43                                   Therefore, we carried out a global and unbiased analysis on previou
44 study the physiological roles of polyamines, we carried out a global microarray analysis on the effec
45                                              We carried out a GWA meta-analysis in 93 926 individuals
46                 To discover additional loci, we carried out a GWAS comparing 6,476 PD cases with 302,
47                                              We carried out a GWAS comparing 73 infants with challeng
48                                              We carried out a GWAS meta-analysis of combined mixed-an
49   To identify novel regulators of TG levels, we carried out a high throughput screen (HTS) using an A
50 vity underlies the RAD52 cellular functions, we carried out a high throughput screening campaign to i
51                                        Here, we carried out a high-throughput, transposon insertion s
52                                        Here, we carried out a longitudinal time-series study to measu
53                                              We carried out a meta-analysis of association studies in
54 he adenomas originate from zona glomerulosa, we carried out a microarray analysis comparing transcrip
55                                              We carried out a more comprehensive meta-analysis of coh
56 avidin-biotin-peroxidase staining technique, we carried out a morphological and electrophysiological
57                                        Here, we carried out a multi-faceted and single-cell resolutio
58                                              We carried out a multicentre cohort study using data fro
59                                              We carried out a multicountry comparative analysis of na
60 ironmental risk factors and HPeV infections, we carried out a nationwide cohort study linking registr
61                       To address this issue, we carried out a nested matched case-control study using
62 0 TLE-HS, 19 TLE-G, and 25 healthy controls, we carried out a novel MRI-based hippocampal subfield su
63                       To examine this trend, we carried out a parallel nested experiment performed si
64 ds clinical diagnosis and disease treatment, we carried out a pilot study and performed Next-generati
65                                              We carried out a population-based cohort study (N=5 901
66                                              We carried out a population-based study of all mother-in
67                                              We carried out a prospective cohort study during 24 mont
68                                              We carried out a proteomic analysis of a B cell lymphoma
69                                              We carried out a quantitative analysis of the inner nucl
70                                              We carried out a quantitative review of 48 modelling met
71                                              We carried out a randomised phase 2 trial of patients ag
72  Following a pilot trial suggesting efficacy we carried out a randomised study in hospital medical cl
73                                              We carried out a randomised, open-label, phase 3 trial f
74                                        Here, we carried out a replicated and controlled drought manip
75                                              We carried out a retrospective review of the electronic
76                                Consequently, we carried out a retrospective study genotyping 345 Germ
77 racteristics of thyroid carcinoma over time, we carried out a retrospective study to illustrate the e
78  all-atom Monte-Carlo unfolding simulations, we carried out a saturating mutagenesis of Dihydrofolate
79                                              We carried out a screen for a potential link between tri
80                   To tackle these questions, we carried out a series of behavioral experiments in sig
81 o investigate the role of HsvA in virulence, we carried out a series of biochemical and structural st
82                                              We carried out a series of experiments to map out and le
83 al differences can have such a large effect, we carried out a series of molecular dynamics simulation
84                                              We carried out a series of tests of structural and funct
85                                              We carried out a structural and biochemical analysis of
86                                              We carried out a structure-function analysis to determin
87 s essential aspect of ion-coupled transport, we carried out a structure-function study on the SMR pro
88                                              We carried out a study between June and July 2010 to ass
89 ntial strategies to decrease this mortality, we carried out a study by analyzing the infant mortality
90 by the Norwegian Institute of Public Health, we carried out a study of nulliparous pregnant women enr
91                                              We carried out a study to compare response times to vent
92                                              We carried out a survey among modeling groups to show an
93 cal modifiers that exacerbate CL deficiency, we carried out a synthetic genetic array screen to ident
94             Using these benchmark data sets, we carried out a systematic evaluation of ten publicly a
95 derived from The Cancer Genome Atlas (TCGA), we carried out a systematic inference of TFs whose misre
96                                              We carried out a systematic literature review identifyin
97  effect of ketamine on the dopamine systems, we carried out a systematic review and meta-analysis of
98 he pathogenesis and treatment of depression, we carried out a systematic review and meta-analysis of
99  the machinery required to resolve clogging, we carried out a systematic screen in Saccharomyces cere
100                                              We carried out a systematic search in PubMed (any date:
101                                              We carried out a systematic search of the databases PubM
102                                              We carried out a third GWAS (GWAS3) in European-ancestry
103                               In this study, we carried out a three-stage epigenome-wide association
104                                              We carried out a three-stage genome-wide association stu
105                                              We carried out a trans-ancestry genome-wide association
106                                              We carry out a comparative study against seven popular a
107                                        Here, we carry out a comprehensive analysis of A-to-I editomes
108                                         Here we carry out a comprehensive molecular and physiological
109                                              We carry out a detailed investigation of the thermodynam
110                                              We carry out a first-principles atomistic study of the e
111                                              We carry out a generally applicable theory to explain th
112                                         Here we carry out a genome-wide association study of breast c
113  1,796 brain samples from 1,163 individuals, we carry out a GWAS of two DNA methylation-based biomark
114                                         Here we carry out a high-throughput computational screening o
115            For pragmatic use and validation, we carry out a marketing campaign that shows a threefold
116 acterize the folding pathway of this protein we carry out a Phi-value analysis and use the resulting
117                                         Here we carry out a SILAC-based quantitative phosphoproteomic
118                               In this study, we carry out a thermodynamic and energy efficiency analy
119 nslocon complex embedded in a lipid bilayer, we carried out all-atom molecular-dynamics simulations o
120                                              We carried out an 18-mo experimental feeding study at 23
121 ing in plant-associated Pseudomonas species, we carried out an affinity capture screen for cdG bindin
122                                              We carried out an evolution experiment, allowing for coe
123                                              We carried out an ex post analysis of a surveillance stu
124                            For this purpose, we carried out an exhaustive sampling in a new successio
125                                              We carried out an experiment in which human decision mak
126                                              We carried out an experiment of this kind on a wild popu
127                                              We carried out an experimental comparison of 140 men and
128                                              We carried out an exploratory examination of psychologic
129 nificance of RBPs during neural development, we carried out an in vivo RNAi screen in the dorsal spin
130 tals interfere with Fe deficiency responses, we carried out an in-depth characterization of Fe-relate
131    Using time-lapse fluorescence microscopy, we carried out an in-depth study of a differentially reg
132                                              We carried out an integrated study of PKD in a prealpine
133                                              We carried out an integrative analysis of enhancer lands
134                               In this study, we carried out an integrative molecular analysis to iden
135                                              We carried out an integrative, longitudinal study combin
136 Using specimens from eleven primate species, we carried out an inter-specific investigation, examinin
137  of AMSH is regulated at the cellular level, we carried out an interaction screen for the Arabidopsis
138          In Palwal District, Haryana, India, we carried out an intervention utilizing the Philips HD4
139                                   Therefore, we carried out an observational study to estimate the oc
140                                              We carried out an RNAi screen in Drosophila S2 cells to
141      To systematically study ERV repression, we carried out an RNAi screen in mouse embryonic stem ce
142                                              We carried out an unbiased analysis of the integrated ce
143                                         Here we carried out an unbiased analysis to identify previous
144         To identify novel druggable targets, we carried out an unbiased high-throughput chemical scre
145 2 expression is regulated downstream of YAP, we carried out an unbiased screen for transcriptional re
146                                In this study we carried out an unbiased screening approach to identif
147                                         When we carry out an act, we typically attribute the action t
148 uorescent protein (EGFP) as a model protein, we carry out an experimental optimization of the ITP-bas
149                                         Here we carry out an in-depth genomic characterization of 64
150                                 Furthermore, we carried out assays to examine the virus entry mechani
151                             Using the model, we carried out automated computational design of 62 synt
152 ir activity and required modification, which we carried out based on previous in vitro work.
153 metabolic basis of the metabolite formation, we carried out biochemical and cellular studies and esta
154                               In this study, we carried out biophysical studies to better understand
155                                Concurrently, we carried out boat-based dolphin photo-identification t
156                                              We carried out both functional kinetic and thermodynamic
157 sitive sites surrounding a gene of interest, we carried out both loss- and gain-of-function screens t
158                                         Here we carry out calculations to answer these questions, bas
159                                  Using SCoRe we carried out chronic brain imaging up to 400 mum deep,
160 ments underlying MOR functional selectivity, we carried out close to half millisecond high-throughput
161                                              We carried out coarse-grained spatial stochastic binding
162  polychaete that supports high biodiversity, we carried out common-garden experiments using individua
163                                              We carried out compound-specific isotope analysis (CSIA)
164                                        Here, we carried out comprehensive evolutionary analyses of th
165                                              We carried out comprehensive mapping of volatile compoun
166 clear Magnetic Resonance (NMR) spectroscopy, we carried out comprehensive metabolite profiling of cul
167                                         Here we carried out CRISPR-Cas9-mediated genome-wide screens
168                                         Here we carry out de novo transcriptomics of five representat
169                                              We carry out deep sequencing of 13 additional inbred str
170 le of CASP8 in breast cancer susceptibility, we carried out dense genotyping of this region in the Br
171                                              We carried out detailed genomic and biochemical analyses
172                                              We carried out detailed ice-phenology mapping of arctic
173                                              We carry out detailed experimental and theoretical studi
174 e conformational properties of these states, we carried out double electron-electron resonance experi
175                                              We carried out dynamic force manipulations in silico on
176                                              We carried out endogenous deletion of the full-length Em
177  become easily activated after purification, we carried out ex vivo comparisons with neutrophils main
178                                              We carried out exome sequencing for parent-offspring tri
179                                              We carried out exome sequencing in persons from multiply
180                                 To this end, we carried out exome sequencing of constitutional genomi
181                                              We carried out exome sequencing on 57 trios with sporadi
182  vine growth, yield, fruit and wine quality, we carried out experimental trials to analyse the YLOID
183 possible role of ANO1 in insulin metabolism, we carried out experiments in Ano1(+/-) mice.
184                                              We carried out experiments to study the capacity of the
185          To examine the recorded signatures, we carried out experiments with spheres impacting at the
186 OR conformations on receptor oligomerization we carried out extensive coarse-grained molecular dynami
187        To shed light on this critical topic, we carried out extensive quantum mechanics/molecular mec
188                                              We carry out extensive molecular dynamics simulations of
189                                              We carried out face-to-face interviews with a consecutiv
190                         As proof-of-concept, we carry out field demonstrations where minimally-traine
191                               In this paper, we carry out first-principles calculations on MnX (X = N
192    To more rigorously assess RECCES-Rosetta, we carried out four blind predictions for stacked pairs
193                      To identify mechanisms, we carried out gene expression analyses and found that s
194                                              We carried out genome-wide analysis of (1) functional ta
195                In the report presented here, we carried out genome-wide copy-number analysis using co
196 s to Huntington's disease (HD) pathogenesis, we carried out genome-wide mapping of the transcriptiona
197    To identify other polycistronic messages, we carried out genome-wide ribosomal profiling and ident
198                               In this study, we carried out genomewide DNA methylation profiling of 1
199                                              We carried out genomic and phenotypic analyses of 215 se
200                                        Here, we carried out genotype analyses by partial PCR sequenci
201                                              We carried out glasshouse experiments using the Californ
202                                              We carried out high-resolution genetic, epigenetic, and
203 vior of the 3D composite microarchitectures, we carry out high fidelity computational simulations of
204                                              We carried out hippocampus-dependent learning and memory
205 -level details of the re activation process, we carried out in situ 450 nm photolysis of E4(4H) in an
206 he two related, but different, HAT complexes we carried out in vitro HAT assays.
207                                Additionally, we carried out in vivo experiments to confirm the safety
208                                 In addition, we carried out in-depth analyses of DNA elimination in t
209 ed to BCRPs To further explore this finding, we carried out in-depth analyses of whole genome sequenc
210                                              We carried out kinetic and thermodynamic experiments to
211                                              We carried out laboratory experiments of a pay-it-forwar
212                                              We carried out MD simulations in both an aqueous solutio
213                                              We carried out metabolic labeling experiments and studie
214 nges in astrocyte-spinal neuron co-cultures, we carried out metabolomic analysis by (1)H NMR spectros
215                                              We carried out metagenomic shotgun sequencing and a meta
216                                              We carried out microarray analysis of transgenic rice ov
217 ene expression changes due to loss of Kcnq1, we carried out microarray studies in the colon and proxi
218 hanges involved in CB2.Gi complex formation, we carried out microsecond-time scale molecular dynamics
219 to the same cargo coordinate their movement, we carried out microtubule gliding assays using pairwise
220  the issue of Gs vs Gi coupling specificity, we carried out molecular dynamics simulations of lipid-e
221 nsfer distances measured with bound ouabain, we carried out molecular dynamics simulations with energ
222                                              We carried out multigene panel testing on all participan
223  dynamics, and allostery in protein kinases, we carried out multiple microsecond-scale molecular-dyna
224                               In this study, we carried out mutagenesis screening in mice to identify
225 underlies such a dynamic and complex system, we carried out mutagenic, biochemical, hydrodynamic and
226                                              We carried out mutation analysis of RAB27A, LYST, and AP
227                                              We carried out mutational analysis of the N-terminal 62
228                                    Moreover, we carry out NMR relaxation experiments to characterize
229                               In this study, we carried out normal-mode analysis and enhanced samplin
230                                    Moreover, we carried out numerical simulations to investigate the
231                                         Here we carried out numerical studies on the InGaN DA showing
232                              To this effect, we carry out numerical simulations to characterize the s
233 ndicates sharp cutoffs, suggesting melanoma, we carried out our experiments on two dermoscopy image d
234 le of I-PTH on the MCC and subchondral bone, we carried out our studies using 4 to 5 week old triple
235                                              We carry out our analysis computationally using a simple
236                                              We carried out padlock capture, a high-resolution RNA al
237 ifferences in UB recognition by UAE and NAE, we carried out phage selection of a UB library with rand
238                                              We carried out phylogenomic analyses using a modified ph
239                                              We carried out pre-steady-state kinetic analysis to eluc
240                                              We carried out protein-dependent yeast growth assays and
241      To identify new cytokinesis regulators, we carried out proximity-dependent biotin identification
242                                              We carried out quantitative analysis of gliadin types by
243                                     However, we carried out quantitative PCR validations which indica
244    Due to the limited amount of SDMA formed, we carried out quantum mechanical calculations to determ
245                                        Here, we carry out Quantum Mechanics (QM) calculations with an
246 date the pathways of perforin pore assembly, we carried out real-time atomic force microscopy and ele
247                                         Here we carried out recordings of large populations of HVC ne
248                                              We carried out replicate experiments across 15 laborator
249                                              We carry out replication using Asian COGS samples (n=522
250                                        Here, we carry out resonant inelastic x-ray scattering (RIXS)
251 coding RNA modifications in gene regulation, we carried out ribosome profiling in budding yeast to ch
252                                              We carried out ribosome profiling of cultured human cell
253                    To address this question, we carried out RNA sequencing studies using fixed, antib
254                         To test this method, we carried out RNA-seq on 20,424 single cells from postn
255  order to confirm our quantitative findings, we carried out RT-PCR and reported RNA-Seq data, which s
256                   To complement experiments, we carried out several pressure jump and temperature jum
257                                              We carried out similar analyses for spirometric restrict
258                                        Then, we carry out simulations on four types of complex networ
259                                              We carried out single-molecule imaging of CHD4 in live m
260                       With the snails found, we carried out snail-parasite compatibility experiments
261                                        Here, we carried out solution analysis utilizing the entire or
262 on depended on the MOBKL1B-NS5A interaction, we carried out structural and biochemical analyses.
263              To understand this specificity, we carried out studies using fluorescence-based methods.
264 lating intracellular and cortical mechanics, we carried out studies using mouse embryonic fibroblasts
265  role of this domain in the stress response, we carried out systematic analysis of all mammalian TLDc
266               To optimize our device design, we carried out systematic simulations of cell trajectori
267                                              We carried out targeted functional analyses on Et skelet
268                                              We carried out targeted gene disruption of the Phypa_PEX
269 beta versus gammadelta T cells in psoriasis, we carried out TCR/delta HTS.
270                                              We carried out tests of replication using an additional
271        In addition, using the same protocol, we carried out the cyclization reaction of relevant mole
272                                              We carried out the first careful search for new viruses
273                                        Here, we carried out the first deep mRNA sequencing analysis o
274                               In this study, we carried out the first screening of GLE1 in ALS patien
275 ntegrating multiple human RNA-seq data sets, we carried out the first systematic prediction of isofor
276                                              We carried out the health check-up on laboratory animal
277                               Based on this, we carried out the rational design and synthesis of two
278                                              We carried out the structural characterization of the th
279                                        Here, we carry out the largest GWAS meta-analysis of MPB to da
280              Based on the signed similarity, we carry out the percolation analysis on this signed uni
281 there are large pores in the structure, here we carry out the transformation under less than optimal
282                                              We carried out this randomised controlled trial at five
283  to abnormalities of the pilosebaceous unit, we carried out three-dimensional morphometric analysis o
284 isms underlying these MK responses to shear, we carried out transcriptional analysis on immature and
285 ailandensis quorum sensing-controlled genes, we carried out transcriptome sequencing (RNA-seq) analys
286          To achieve broad coverage of genes, we carried out transcriptome sequencing and deep proteom
287                                              We carried out two experiments: in the factual learning
288            Using female Sprague-Dawley rats, we carried out two rounds of experiments with oral gavag
289                                              We carried out two-sample Mendelian randomization analys
290 nusual nature of some of the mutant alleles, we carried out ultra-deep next generation sequencing to
291 rtant aspect of GPCR functional selectivity, we carried out unbiased microsecond-length MD simulation
292                                              We carried out untargeted metabolomic analysis of sera c
293                                              We carry out valley qubit operations at multiple charge
294                                              We carried out whole exome and genome sequencing and fou
295 both essential tremor and Parkinson disease, we carried out whole exome sequencing and pedigree analy
296 ng variants with large effects on LOAD risk, we carried out whole-exome sequencing (WES) in 14 large
297                                              We carried out whole-exome ultra-high throughput sequenc
298 ermine how these are functionally organized, we carried out whole-genome transposon mutagenesis scree
299                                         Here we carry out whole-exome sequencing in an infant with ev
300  role of host cell proteins in Vpu function, we carried out yeast two-hybrid screening and identified

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