ライフサイエンスコーパス: we designate

1 In a cluster-randomized study, we designated 15 clusters with 78,744 miners as either i

2 In the novel spliceoform, an exon we designate "15b" replaces the canonical exon "15a", an

3 We designate 18 ion channel genes that are differentiall

4 ining characteristic of the WrbA family that we designate a new type of NQO (type IV).

5 three distinct states of antithrombin, which we designate A, A', and B.

6 e with tumors expressing this profile, which we designated acini-like tumors, had a significantly low

7 the discovery of a novel AFX isoform, which we designated AFX zeta, in which the first 16 amino acid

8 tantial levels of a slower migrating species we designate age-specific mtDNAs.

9 We designated AH9 antigen as a limbic system associated

10 with a locus on distal chromosome 11, which we designate ahl8.

11 nases are AvtA, YfbQ (AlaA), and YfdZ (which we designate AlaC).

12 Of the total of 1,510,064 births, we designated all 86,224 preterm births as the case grou

13 DivIB comprises three discrete domains that we designate alpha, beta, and gamma from the N to C term

14 In P. aeruginosa, a gene, which we designated aminoglycoside response regulator (arr), w

15 ntified by electron cryo-microscopy and this we designate an R to R* transition.

16 ncoding an angiopoietin-related protein that we designate angioarrestin.

17 ed cationic lipid-PLGA hybrid nanoparticles; we designated antigen-adsorbed (out), antigen-encapsulat

18 metabolism to a sesquiterpene epoxide, which we designate arteannuin X.

19 WWG-ethanolamide, in which n = 4 or 8, which we designate as "N-anchored" and "C-anchored" peptides,

20 g families of positional loop isomers, which we designate as "rollamers".

21 d, short-armed Liaoning dromaeosaurid, which we designate as a new genus and species, Zhenyuanlong su

22 similar to Com1 of Coxiella burnetii, which we designate as dsbA2.

23 The gene for VHZ, which we designate as DUSP25, is located on human chromosome 1

24 ally folded thermodynamic intermediates that we designate as F (most folded) and I (intermediately fo

25 ngs to the histone deacetylase family, which we designate as HDAC11.

26 ich is mediated by DNA looping, a phenomenon we designate as intersegmental hopping.

27 e identified approximately 135 proteins that we designate as long-lived asymmetrically retained prote

28 ved with the Rad1-Rad10-Rad14 complex, which we designate as nucleotide excision repair factor-1, NEF

29 The enzyme, which we designate as PurP, is the product of the Methanocaldo

30 of the Cockayne syndrome A (CSA) gene, which we designate as RAD28.

31 s via modulating auxin homeostasis for which we designate as reset, not to be confused with the gravi

32 , and argue that this layer structure, which we designate as smectic-fA phase, is thermodynamically s

33 14D12 to amino acids Gln(29)-His(53), which we designate as specific epitope 1 (SE1).

34 Thus, the CRFB4 chain, which we designate as the IL-10R2 or IL-10Rbeta chain, serves

35 ocated in the periplasmic domain, in regions we designate as the lower part of the large external cle

36 ow that the N-terminal region of gp41, which we designate as the neurotoxic domain, induces iNOS prot

37 he first example of a class of proteins that we designate as trypanokines, i.e., factors secreted by

38 ndomized to receive electrical shocks (which we designated as "experimental shocks") immediately befo

39 lated rats received additional shocks (which we designated as "rescue shocks") after 8 mins of chest

40 and characterization of a novel protein that we designated as calcineurin/NFAT-activating and immunor

41 e genes is a member of a CT gene family that we designated as CT45.

42 les, mitochondria, and lipid droplets, which we designated as granule-containing vesicles (GCVs) and

43 at the base of the isolated stem-loop, which we designated as high-frequency recombination sites 1 an

44 atecholamine-O-methyltransferase (COMT) that we designated as low pain sensitivity (LPS), average pai

45 histocompatibility complex (MHC) gene, which we designated as MHC Q1b, whose expression decreases in

46 gene identified on chromosome arm 5BS, which we designated as Snn3.

47 e discovered a 29-bp consensus sequence that we designated as the Clock-Associated Transcriptional Ac

48 allowed us to discover a novel compound that we designate aspercryptin and to propose a biosynthetic

49 homologous Arabidopsis thaliana gene, which we designated AtPGM.

50 ified the putative two-component system that we designated Bacillus anthracis respiratory response (B

51 to either K332 in L5, forming a product that we designated band 1, or to the major outer membrane pro

52 se genes mapped to two adjacent operons that we designated bbcABCDEF and bbcGHIJK.

53 a novel 399 bp repetitive DNA element (which we designate beta) 9bp upstream of a seryl-tRNA(CAG) gen

54 that include or exclude a short domain that we designate beta.

55 lly distinct lineage within subtype C, which we designate C(IN).

56 ew member of the alpha-CA gene family, which we designate carbonic anhydrase-related protein XI (CA-R

57 As such, we designated CBU0077 MceA (mitochondrial Coxiellaeffect

58 The two other proteins, which we designated CC1 (for crenarchaeal chromatin protein 1)

59 family transcription factor PGN_1373, which we designate CdhR, in this control pathway.

60 usly described cysteine desulfhydrase, which we designated cdsH (formerly STM0458).

61 Adjacent to the cepR2 gene is a gene that we designate cepS, which encodes an AraC-type transcript

62 he human cytomegalovirus (CMV) genome, which we designated cmvIL-10.

63 ng a 27-kDa protein of unknown function that we designated COLD-REGULATED GENE 27 (COR27; At5g42900).

64 amily and is regulated by its product, which we designate ComR.

65 olecular transfer between E1 and Ubc9, which we designate "cross-sumoylation." Rhes binds directly to

66 d gene that regulates cdsH expression, which we designated cutR (formerly ybaO, or STM0459).

67 ma(54)) and an RpoN-dependent activator gene we designate dgaR.

68 We isolated a novel DGK, which we designated DGKiota, from human retina and brain libra

69 variants with R5-tropic-like V3 loops, which we designated "dual-R," use CCR5 much more efficiently t

70 A distinct superfamily of kinases, which we designated DxTN after its sequence signature, appears

71 rom an overlapping open reading frame, which we designate E10.

72 ntified a novel member of this family, which we designate endoglycan.

73 ced sequence of a novel beta-defensin, which we designate enteric beta-defensin (EBD).

74 sis and M. marinum genes in this region that we designate extRD1 (extended RD1).

75 rbohydrate recognition sequence motif, which we designate F-type.

76 ve domain in laminin-gamma3 domain IV, which we designate F5 peptide, and show that the overexpressio

77 That protein, which we designate FdIV, has now been purified.

78 oding a novel member of the FGF family, that we designate FGF-20.

79 1 via a 14-kDa, surface-exposed protein that we designated FhbB.

80 aled that these proteins are isoforms, which we designate G1 and G2.

81 three members in Arabidopsis thaliana, which we designated GALACTAN SYNTHASE1, (GALS1), GALS2 and GAL

82 that include or exclude a short domain that we designate gamma.

83 on the deduced amino acid sequence identity we designated GAPC1 and GAPC2 as group I (97% identical)

84 uman CMV, pp71 (UL82) and pp65 (UL83), which we designated GP82 and GP83, respectively.

85 A PAL gene we designated gPAL1, cloned from tobacco, consists of tw

86 Saccharomyces scSPT23 and scMGA2 genes that we designate here as caSPT23.

87 onarily distinct human haplogroups (HH) that we designated HHA, -B, -C, -D, -E, -F, and -G.

88 The AK000411 protein, which we designate hIntersex (human Intersex), shares signific

89 of the binding partner of human MUS81, which we designate hMMS4.

90 One of these genes, which we designated hmsP, encodes a putative phosphodiesterase

91 ectly upstream of the hmuR gene a gene which we designated hmuY.

92 One of these, which we designated HVEM-L, specifically bound to HVEM-Fc with

93 dispersed innate type 2 helper cells, which we designate Ih2 cells, play an integral role in type 2

94 cterized one kinase from this complex, which we designate IKKepsilon.

95 In this system, which we designated "in-microbe", reactions occur within 2 to

96 code distinct but paralogous proteins, which we designate interferon-lambda1 (IFN-lambda1), IFN-lambd

97 were confined to a short DNA sequence, which we designated ipeX for inhibition of porin expression, a

98 by an insertion sequence-like element which we designated IS195.

99 w family of glycosyltransferases; therefore, we designate it as a GT-D glycosyltransferase fold.

100 (NAP1) and to a human homologue of NAP1, and we designate it hNAP2 (human nucleosome assembly protein

101 We designate it Pa-MIG.

102 We designate it the ArnA transformylase domain and descr

103 natural ligand for the cortactin SH3 domain, we designated it CortBP1 for cortactin-binding protein 1

104 , such as cAR1 and GP80, during development, we designated it early gene expression A (ege A).

105 f this protein superfamily, and consequently we designated it HSP22.

106 rmation of an extended stem structure, which we designated JFH-SL9074.

107 ct polyribitol-containing teichoic acid that we designate K-WTA.

108 e KEEP ON GOING gene (KEG; At5g13530), which we designated keg-4.

109 Ralpha.IL-4.gammac]/[IL-4Ralpha.IL-4], which we designate KR.

110 ique mixed-domain lamellar morphology, which we designate LAMP Transmission electron microscopy indic

111 This gene, which we designated Ly-6M, shares several structural features

112 han any other member of the family and which we designate mammalian inositol phosphate multikinase (m

113 bacterial histidine acid phosphatase, which we designated Map for major acid phosphatase.

114 The gene, which we designate mcrA, is conserved but uncharacterized, and

115 al evidence that the FLJ10193 protein, which we designate Med25, is a bona fide subunit of the mammal

116 n rare-cleaving nuclease architecture, which we designate 'megaTAL', in which the DNA binding region

117 This phenomenon, which we designated "mitotic drive" , is a novel mechanism whi

118 here that a mouse Mps1p ortholog (esk, which we designate mMps1p) regulates centrosome duplication.

119 ovel ATP-binding cassette transporter, which we designated MOAT-B.

120 the odds [LOD] score = 6.9, P < .0001) that we designate Modifier of hemostasis (Mh).

121 d protein encoded by the FLJ10914 ORF, which we designate MRGBP, as a new component of the TRRAP/TIP6

122 es: Muscle RING Finger 1 (MuRF1), and a gene we designate Muscle Atrophy F-box (MAFbx), the latter be

123 The homology of the predicted protein, which we designated NAG (neuroblastoma amplified gene), to a C

124 Arabidopsis thaliana flagellin receptor that we designated NbFls2.

125 eration and activity of a truncated receptor we designate NDeltaCterm.

126 tylase/GlcN N-sulfotransferase family, which we designate NDST4.

127 promoters were located upstream of loci that we designated nipAB and nipC, which correspond to hcp-hc

128 t encoding a G protein-coupled receptor that we designated NmU-R2 based on its homology to NmU-R1.

129 o identified a gene in N. gonorrhoeae, which we designated nuc.

130 iosulfate and vectorial sulfur transfer, and we designate NWMN_0026.5 as CstR (CsoR-like sulfur trans

131 hat the two components of this system, which we designate OtpA and OtpB, are not predicted to belong

132 involves a structural transition to a state we designate P.

133 6, 32, 38.9, 30.1, 12.7, and 75.7 kDa, which we designated p5.6, p32, p39 (NTPase), p30, p13 (VPg), a

134 e, and Caenorhabditis elegans homologs which we designate PET.

135 ich encodes a 6-phosphogluconolactonase that we designated pglA.

136 Intensely orange fluorescent adducts, which we designate phytofluors, are spontaneously formed upon

137 elated family of seven human proteins, which we designate PLUNC proteins.

138 B), also encodes a novel DNA polymerase that we designate poliota.

139 With these findings, we designate pp105 as Cas-L, lymphocyte-type Cas.

140 We designate PPE15 as mycobacterial perilipin-1 (MPER1).

141 We designate priority countries for such actions, recogn

142 ied type of disease involving the PrP, which we designated "protease-sensitive prionopathy" (or PSPr)

143 , we isolated an ethanolamine auxotroph that we designate pstA1-1.

144 ne-spanning enzyme II(Glc) of the PTS, which we designate ptsG-F.

145 ts in spatially discrete micro-domains which we designate "puncta," and the relative amounts of each

146 genes involved in PvGal biosynthesis, which we designated pvg1-pvg5.

147 We defined Rab-conserved sequences that we designate Rab family (RabF) motifs using the conserve

148 t of the plasmid can be attributed to a gene we designate rapP.

149 ial Y-box protein in Trypanosoma brucei that we designated RBP16.

150 0836 and SMu0837 encode ABC exporters, which we designated rcrPQ (rel competence-related) genes, resp

151 ion yeast homologue of mammalian Rheb, which we designated Rhb1, was identified by genome sequencing.

152 ithelial cells that is dependent upon a gene we designated rtxA.

153 he gene encodes a membrane-bound enzyme that we designate SCALD, for short-chain aldehyde reductase.

154 n over 125 genomes, featuring a peptide that we designate SCIFF (six cysteines in forty-five residues

155 ulates in senescent human fibroblasts, which we designated senescence-associated heterochromatic foci

156 we propose that they belong to a group which we designate SIS, for SA-independent, systemically induc

157 nus, the l'hoest monkey (C. l'hoesti), which we designated SIVlhoest.

158 stationary phase and noted a protein, which we designated Snz1p (p35), that shows increased synthesi

159 and two fibronectin type-III domains, which we designate stretchin-MLCK.

160 eviously uncharacterized zinc-finger protein we designate TELOMERASE ACTIVATOR1 (TAC1) is overexpress

161 ons involving AR-interacting proteins, which we designate the "AR-interactome." Despite many years of

162 s a cavity masked by an acidic linker, which we designate the "FLAP." Analysis of three mutant moesin

163 e find that the NH(2)-terminal region, which we designate the actin-targeting domain, facilitates ZNF

164 We designate the alternative pathway for the interconver

165 a novel, full-length 6.9-kb muscle cDNA, and we designate the corresponding protein 'dysferlin'.

166 aracterized type of protein methylation, and we designate the enzyme as Rmt2 (protein arginine methyl

167 We designate the first complex as (pol beta)16 and the s

168 We designate the first complex as the (pol beta)16 bindi

169 ubunit complex from the two-subunit Polzeta, we designate the four-subunit enzyme "Polzeta-d," where

170 ialidase function - and for this distinction we designate the gene and encoded protein nonA/NonA.

171 Based on our findings, we designate the gene product corresponding to ct694-ctl

172 hosphotransferase system (PTS) permease, and we designate the genes encoding the permease dgaABCD (d-

173 We designate the large complex seen in wild-type cells c

174 uniqueness of this group of isolates, which we designate the Manila family of M. tuberculosis.

175 We designate the mutant xax1 for xylosyl arabinosyl subs

176 We designate the novel gene PAGE-1 because the expressio

177 We designate the original 4-phosphatase and the new isoz

178 ng frame is similar to that of rat APT1, and we designate the protein S. cerevisiae Apt1p.

179 y a global termination control system, which we designate the S box system, as most of the genes are

180 pathway described in M. tuberculosis, which we designate the Snm pathway.

181 One of these is a novel sequence motif that we designate the SNOG element, because it occurs downstr

182 We designate the type strain NSH-16 (= ATCC BAA-2463 = N

183 ology with human DNA ligase IV; accordingly, we designate the yeast gene LIG4.

184 Therefore, we designated the agent as a helper-dependent E1-positiv

185 We designated the B. melitensis protein Omp28.

186 We designated the C. pneumoniae homologue as CPAFcp.

187 ently described 50.6% identical protein that we designated the CILP-2 isoform.

188 We designated the corresponding soybean gene GmPGM.

189 oth host cells were highly similar, and thus we designated the defective loci in these mutants pmi (f

190 new family of avian endogenous viruses that we designated the ev/J family.

191 We designated the first phase of dissemination "adherenc

192 on the phenotype displayed by its mutation, we designated the gene corresponding to Cj0643 as cbrR (

193 We designated the gene for this manganese efflux system

194 hly conserved in Bartonella hbp genes, which we designated the hbp family box, or "H-box." Fourth, we

195 the basis of their similarity to these loci, we designated the L. pneumophila genes helC, helB, and h

196 g motif within the nocturnin promoter, which we designated the nocturnin element (NE).

197 We designated the pattern as female if the J point was <

198 he phenotype of the C. jejuni Cj1242 mutant, we designated the protein Campylobacter invasion antigen

199 j1279c harbors fibronectin type III domains, we designated the protein FlpA, for fibronectin-like pro

200 rphism, CTG-->GTG (Leu-->Val), at codon 125; we designated the resulting alleles CD31.L and CD31.V, r

201 ntly aborted opposite template T, a property we designated the T stop.

202 ene uncovered a novel C-terminal domain that we designated the Tsunami Homology (TH) domain.

203 pneumophila to mammalian cells and protozoa, we designated the type IV pili CAP (for competence- and

204 ibed virus of the Flaviviridae family, which we designate "Theiler's disease-associated virus" (TDAV)

205 We designate them as "class I ERPs." We originally hypot

206 tionally distinct from the beta-subunits and we designate them as a gamma family of the BK channel au

207 Here we designate them as a new family, the Mohoidae.

208 We designate them as female-nest-coo-specific units.

209 Previously designated RepX and TubZ, we designate them here as TubZ-Ba and TubZ-Bt.

210 For this reason we designate them Ksust ('sustained current') channels.

211 pithelium and stroma are affected diffusely, we designated them as "atypical hyperplasia of Tag." Alt

212 Based on the characteristics of each class, we designated them as follows: 'Nonresponders' (n = 905,

213 We designate these isoforms SMRTalpha and SMRTtau and de

214 We designate these light chains type III.

215 We designate these mice BrtlIV (Brittle IV).

216 We designate these newly described cells as T1d B cells

217 We designate these populations transitional (T) 1 (AA4(+

218 We designate these proteins containing leucine (L) and i

219 We designated these as state S and state I.

220 related with the melanocyte growth kinetics; we designated these clusters the melanocyte growth arres

221 We designated these peptides Pepcan-12 (RVDPVNFKLLSH) to

222 We designated these proteins "magphinins," because they

223 known mammalian thiamine transporter, which we designate thiamine transporter-1 (THTR-1).

224 We designate this 5-phosphatase as type IV.

225 We designate this approach "genetic vaccinology," since

226 We designate this approach as Scanning Probe Potential E

227 We designate this approach the LD decay (LDD) test.

228 and chromosomal location of this chemokine, we designate this chemokine small inducible cytokine sub

229 Thus, by analogy to the Notch receptor, we designate this cleavage the S2 cleavage site, whereas

230 n of ADP ribosylation factor by cytohesin-1, we designate this cytokine-inducible protein Cybr (cytoh

231 We designate this difference DNA bending cooperativity.

232 Therefore, we designate this enzyme KAS IV, a medium chain specific

233 We designate this factor CPF, for CYP7A promoter binding

234 We designate this fusion protein as IcmF (isobutyryl-CoA

235 We designate this GAP43-CerFP-t-h-ras construct as hVoS

236 motility and a hyperbiofilm phenotype; thus, we designate this gene bifA, for biofilm formation.

237 gene with two HMG boxes and an acidic tail; we designate this gene LfHMG1.

238 membrane organic cation transporters; hence, we designate this gene ORCTL2 (organic cation transporte

239 We designate this hominin population 'Denisovans' and su

240 We designate this inhibitory site(s) as the I site.

241 By analogy with related regulatory systems, we designate this leader RNA pattern the "L box." Genes

242 We designate this mechanism-causing regulated inversion

243 To distinguish the two unrelated families we designate this new class DGAT2 and refer to the M. ra

244 We designate this novel gene lba for LPS-responsive, bei

245 We designate this nucleolar focus the No-body and propos

246 Based on sequence homologies, we designate this PDE as PDE7B.

247 We designate this phenomenon 'genomic hitchhiking'.

248 We designate this property "volatility" and apply it to

249 We designate this protein as Gab2.

250 We designate this protein enamel matrix serine proteinas

251 We designate this reaction pyrovanadolysis.

252 We designate this state as "preborder"; its transcriptom

253 ypic, homeostatic, and migratory properties, we designate this subset peripheral memory (tpm) cells a

254 We designated this autophagy-related (ATG) gene as ATG32

255 We designated this clone e3B1 for eps8 SH3 domain bindin

256 We designated this condition PMSE syndrome (polyhydramni

257 ns a functional cis element(s) in vitro, and we designated this element the DCE (downstream core elem

258 Based on these properties, we designated this enzyme Sf9 alpha-mannosidase III and

259 We designated this gene as POLYGALACTURONASE INVOLVED IN

260 Accordingly, we designated this gene CTL1 (capping enzyme RNAtriphosp

261 We designated this locus Mvwf for "modifier of VWF." Add

262 Therefore, we designated this molecule JIK for JNK/SAPK-inhibitory

263 tants described in motheaten (me, mev) mice; we designated this new genotype as Ptpn6(meB2/meB2) and

264 We designated this novel ubiquitously expressed nuclear

265 We designated this putative lipoprotein LipL45.

266 lized the disease locus to a region in 3q29; we designated this region the morbid obesity 1 (MO1) loc

267 We designated this regulator FarR to signify its role in

268 We designated this tally as the allogenomics mismatch sc

269 We designated those rats with an initial increase in car

270 ch is phylogenetically distinctive and which we designate topoisomerase IA(mt).

271 transferase in Saccharomyces cerevisiae that we designate Trm9.

272 Fibres we designated 'type alpha-cardiac' were different from t

273 This new splice variant, which we designate (V+C)-, represents the majority of fibronec

274 ) were lineage D2, 7 (8.4%) were a haplotype we designated "X6," and 3 (3.6%) were a haplotype we des

275 signated "X6," and 3 (3.6%) were a haplotype we designated "X7." Sequence analysis found 43 haplotype

276 Here we designate YKL741 as PXA2 and show that its protein pr

277 esis identified a LysR-like regulator, which we designated YtxR.

278 cia has an additional metalloprotease, which we designated ZmpB.