ライフサイエンスコーパス: well

1 for the inhibition of FcgammaR signaling as well.

2 aptic activity occurring in distant sites as well.

3 potential as nervous system therapeutics as well.

4 een identified in coding (messenger) RNAs as well.

5 aerosols emitted by dairy operations extends well above 10 mum in diameter and contains a diverse mix

6 nvestigated the hydration state of the deep, well-accessible hydrophobic S1' specificity pocket of th

7 The rate of miR487b editing, as well as 2'-O-ribose-methylation, is increased in murine

8 ymptoms, health status, and AF treatment, as well as 2-year risk of death, hospitalization, thromboem

9 ical consequences of laparoscopic surgery as well as a defined operative plan generated by a multidis

10 llular biology of New World arenaviruses, as well as a discussion of the current animal models of inf

11 foreign DNA, such as phages and plasmids, as well as a revolutionary gene editing tool.

12 speciation, hybridization, domestication, as well as about the molecular machineries underlying them.

13 nce and integration into the ICU setting, as well as acceptability of 23 published palliative care pr

14 nd actin cytoskeleton signalling pathways as well as activation of inflammatory pathways.

15 Axin2 is expressed by Lgr5(+) cells, as well as adjacent, highly proliferative Lgr5(-) cells tha

16 -2 alone or in combination with adjuvants as well as adjuvanted subunit vaccines were successful in t

17 e-linked immunospots, cytotoxicity assays as well as adoptive transfer in NOD/SCID/IL2Rgamma mice wer

18 decision making and its neural correlates as well as alcohol expectancies in alcohol-dependent patien

19 ers and suppresses sarcosphere formation, as well as ALDH activity.

20 onTaster2 and FATHMM was found to perform as well as all tools combined.

21 trile)) increasing the rate dramatically, as well as altering the apparent order of reaction.

22 parities in gastrointestinal cancer risk, as well as approaches that apply precision medicine methods

23 ogen- and oxygen-containing heterocycles, as well as aromatic-containing pharmaceutical agents.

24 erall allochthonous and autochthonous DOM as well as associated DBP formation are changed during an e

25 tly presenting with recurrent infections, as well as associated immune dysregulation manifesting as a

26 lay a crucial role in auditory perception as well as attention.

27 closure, tall trees, and uniform height, as well as avoiding canopy gaps and moving toward emergent

28 t may give rise to painful oral symptoms, as well as be a reservoir for infection at other sites of t

29 potently inducing IL-1beta transcription, as well as boosting the ability of LPS to induce IL-1beta m

30 rents near the action potential threshold as well as by enhanced recruitment of inputs arising from s

31 l changes observed on clinical funduscopy as well as by pseudocolor, autofluorescence, and OCT imagin

32 vity during the action potential plateau, as well as by the increase of cytosolic Ca(2+) associated w

33 increase was inhibited by pertussis toxin as well as by wortmannin but not by AG1478, indicating that

34 d pluripotent stem cells with trisomy 21, as well as cancer cells.

35 a diverse array of different heterocyclic as well as carbocyclic products.

36 ive oxygen species, mitochondrial health, as well as cell morphology and determine that the hMSCs are

37 tion of chytrids to trophic interactions, as well as co-evolutionary feedbacks of fungal parasitism o

38 e essentiality of a Pol I-transcribed ES, as well as conserved VSG 3'UTR 16-mer sequences for the gen

39 beta variable gene 2 (TRBV2) in vaccinees as well as controllers.

40 induction of osteoclast (OC) cell fusion, as well as DC-mediated immune regulation.

41 ater, drinking water, and aquarium water, as well as dechloridized seawater) decreases the pH down to

42 ghness has been reported to both increase as well as decrease colloid retention.

43 ions inside cells, de novo protein design as well as defining the role of protein misfolding in neuro

44 s corroborated by mutagenesis experiments as well as detailed atomistic simulations.

45 pe is demonstrated for both quinazolinone as well as diaryliodonium triflates.

46 finities (FIAs) of the hydroalane adducts as well as DIBAL-H in its aggregation states support this e

47 inally, minimal use of intermediary steps as well as direct, late stage C-7 hydroxylation provides bo

48 clear trans-synaptic signal transduction, as well as downstream misregulation of both pre- and postsy

49 s can have strong impacts on biodiversity as well as ecosystem functioning.

50 an ultrasound examination every 6 months, as well as endoscopic evaluations.

51 ermine and compare levels of glutathione, as well as ergothioneine, in different species of mushrooms

52 the tension between these two objectives as well as evaluate disparate racial impacts.

53 l mediators for the corresponding traits, as well as examples of trans-mediators (TAGAP for LDL chole

54 fic expression in microdissected tissues, as well as expression in neonatal prostate.

55 n, cell spreading, and neurite outgrowth, as well as for RhoA activation.

56 for a range of thermodynamic conditions, as well as for saturated argon vapour.

57 ld significant benefits for pathway flux, as well as for toxicity mitigation.

58 All peptides, as well as full length Sap6, demonstrated amyloid propertie

59 Biochemical as well as functional experiments revealed that Spt6 could

60 that is capable of generating GDP-glucose as well as GDP-mannose.

61 nt to rescue the increase in proteinuria, as well as glomerular water permeability, in the context of

62 y inhibited tumor-initiating frequencies, as well as growth rates of BCSC-derived tumor xenografts in

63 ncreased NSC proliferation, and CD44-null as well as HA-disrupted wild type NSCs demonstrate delayed

64 ar foci corresponding to epigenetic marks as well as heterochromatin and the nucleolus also appeared

65 alterations in enterohepatic circulation, as well as host and microbiota bile acid metabolism, favor

66 nti-tau potency of Hsp90/Hsc70 inhibitors as well as Hsc70 variants (WT & E175S).

67 e relevant to a variety of human diseases as well as human aging.

68 iRNA)-processing enzyme Dicer (ADicerKO), as well as humans with lipodystrophy, exhibit a substantial

69 uronic acid and UDP-N-Acetyl-Glucosamine, as well as hyaluronic acid synthase which forms the disacch

70 rom desulfonation and/or denitrification, as well as hydroxylation of photo-oxidized heterocyclic rin

71 NK-1 gene and surface protein expression, as well as IKbeta-alpha phosphorylation.

72 and route of administration of sedatives as well as image quality.

73 led "recent thymic emigrants") in adults, as well as in babies.

74 homotopic cortical and hippocampal areas, as well as in cortico-striatal pathways, emerges primarily

75 otein is localized at the plasma membrane as well as in endosomes and soluble in the apoplast.

76 n infants and pregnant women with malaria as well as in healthy individuals.

77 procedures in MA high/low drinking mice, as well as in isogenic C57BL/6J mice that varied in their M

78 models of retroviral AML transplantation, as well as in retrospective analyses of adult patients with

79 modeling likely occurs in human athletes, as well as in rodent models.

80 n the formal and informal private sector, as well as in the public sector, could help identify the ma

81 altered locomotor sensitization profile, as well as increased responding for and intake of cocaine i

82 timization of azobenzene switching in new as well as indirect ways.

83 age, ethnicity, birth country and weight, as well as infant gender, birth year and birth month.

84 ed with uni- and multivariate statistics, as well as internal validation and propensity score matchin

85 isms in (involuntary) adipose tissue loss as well as its systemic metabolic consequences are far less

86 um, a group of uncultivated archaea that, as well as Lokiarchaeota, includes Thor-, Odin- and Heimdal

87 GEO data using both a heuristic approach as well as machine learning.

88 Using confocal and electron microscopy as well as mathematical analyses, we examined the hydraulic

89 by using SAS 9.3) provided median values, as well as means and 25th and 75th (DRL) percentiles for vo

90 iverse collection of sequences from human as well as model and non-model organisms has been used to a

91 targeting, recognition and biocatalysis, as well as molecular information storage.

92 rformance, leading to faster access times as well as more accurate orientation reproductions for item

93 atforms of genes for vaccines or therapy, as well as more rapid development of countermeasures agains

94 d-type and Rheb-deficient CD4(+) T cells, as well as murine CD4(+) T cells activated in the presence

95 liferation, leading to neovascularization as well as neuroprotection in mammals.

96 Respiration is a rhythmic activity as well as one that requires responsiveness to internal and

97 0.001), and OPN-HpAb (0.801, P = 0.006), as well as one-biomarker of PGI/II (0.735, P < 0.001), HpAb

98 Two sources of 3T3-L1 preadipocytes as well as OP9 preadipocytes were assessed for cell prolife

99 odification in neurodegenerative diseases as well as other pathological conditions.

100 e recovery), inferior event-free survival as well as overall survival in both trials.

101 isturbance of energy and lipid metabolism as well as oxidative stress.

102 nflammatory response in healthy subjects, as well as patients with psoriasis or eczema.

103 sh human MutLalpha interaction with PCNA, as well as PCNA-dependent activation of MutLalpha endonucle

104 ing warmer and more variable temperatures as well as physical flux in natural populations, which will

105 rce acquisition, growth, and competition, as well as plant impacts on ecosystem processes.

106 e scores in MOG35-55-induced progressive, as well as PLP138-151-induced relapsing-remitting experimen

107 me under electrical injection of carriers as well as polariton lasing up to 200 K under non-resonant

108 nt and vitreoretinal interface disorders, as well as potential future prophylactic and treatment stra

109 tial reasons to explain this observation, as well as propose a recommended schema for a randomised ph

110 We tested SiNVICT on simulated data as well as prostate cancer cell lines and cfDNA obtained fr

111 and statistical analysis of the results, as well as provide troubleshooting tips and identification

112 equivalent to that of visual assessment, as well as providing complementary information.

113 2, significantly reduced PGE2 production, as well as PSaV replication.

114 vascularization and stromal tissue growth as well as reduced glandular secretory activity of the lesi

115 and downregulation of LC3-I/II conversion as well as reduced Tfeb expression.

116 cade, including ERK1/2, FAK, AKT and PAK1 as well as regulation of the growth, cytoskeleton remodelin

117 showed more rapid developmental progress, as well as relative to all LR infants.

118 among others, eicosanoid-forming enzymes as well as relevant transcription factors, allowing us to b

119 diverse aspects of growth and development as well as responses to biotic and abiotic factors.

120 d-derived dendritic cells and macrophages as well as resting T-cells, SAMHD1 blocks HIV-1 infection t

121 ries including metabolism and cell cycle, as well as RNA- and protein-modifying enzymes that function

122 s defined by first-order cues (luminance) as well as second-order cues (contrast, texture).

123 ts very efficient use of the template DNA as well as sequence reads, which are nearly all confined to

124 mphomas and lymphoproliferative diseases, as well as several other types of cancer.

125 This level of accuracy for classification as well as severity prediction far exceeds any other approa

126 Thus sortilin-dependent as well as sortilin-independent sorting mechanisms target a

127 cific neurotransmitters and neurocircuits as well as specific behaviors.

128 Reduction in size of lesions as well as subjective improvement of symptoms.

129 oughly exploits the nucleation and growth as well as subsequent superlattice transformation of NC ass

130 lycoproteins required for cellular entry, as well as tegument proteins involved in regulating lytic r

131 ficantly more vulnerable to acidification as well as the additional stressors.

132 ehaviors related to its editing activity, as well as the antagonizing effect of RBP binding on miRNA

133 risk score) versus all others (WOSCOPS), as well as the association between the polygenic risk score

134 r of neurons in the human nervous system, as well as the cellular and molecular reorganization of its

135 tes and mesylates for follow-up reactions as well as the comparison of different electrochemical set-

136 y the medium volume, the cell confluence, as well as the discharge voltage.

137 he catalytic subunit of the PRC2 complex, as well as the E2F2 and FOXM1 transcriptional networks.

138 is includes novel developments in SI-CRP, as well as the emergence of novel applications such as cata

139 ication of the available electrical power as well as the energy density extracted from small syntheti

140 H2AZ regulates transcriptional activation as well as the maintenance of gene silencing, while H2AX is

141 resulting non-uniform phase distribution, as well as the micron-scale essence of the spatial and temp

142 urations with broadband mixing are found, as well as the more complex three-component configurations

143 diversity in natural product biosynthesis as well as the parallels with synthetic organic chemistry.

144 mation of polyglutamine-expanded proteins as well as the pharmacodynamics readouts to monitor their e

145 ical, clinical and regulatory unmet needs as well as the prerequisites for clinical validation.

146 rmal decomposition of water and methanol, as well as the reactions of CO and CO2 over TMC surfaces.

147 direct interaction between L1 and Reelin as well as the Reelin-mediated generation of L1-80 contribu

148 k of AF in relatives of patients with AF, as well as the relative contributions of heritability and s

149 although non-human primate (NHP) studies as well as the RV144 vaccine trial indicate that non-neutra

150 sical polarity and size asymmetry itself, as well as the subsequent activation of distinct fate progr

151 imates of reengagement among all patients as well as the subset of LTFU patients who were alive, cont

152 eral other African and European countries as well as the United States, with limited further transmis

153 Analyses by flow cytometry as well as the use of Cldn14-lacZ knock-in reporter mice co

154 f the ASCO frameworks with the ESMO-MCBS, as well as their correlations with QALYs and with NICE/pCOD

155 on mammalian genomes and transcriptomes, as well as their organization and regulation.

156 ss of function (LOF) alleles was compared as well as those that were wildtype, heterozygous, or homoz

157 stimuli under various external conditions as well as to changes in network parameters arising from le

158 oltage to track [2] and control [3] prey, as well as to exhaust prey by causing involuntary fatigue t

159 respond to endogenous stimuli in new ways as well as to exogenous stimuli, such as temperature, magne

160 o the different NOTA-modified somatropins as well as to gallium chelated NOTA-functionalities (Ga-10:

161 eased resistance to Plasmodium infections as well as to systemic and oral bacterial infections.

162 between travel time and major amputation as well as travel time and revascularization strategy; howe

163 ssment of their gastrointestinal symptoms as well as treatment safety and tolerability.

164 ive Rac in adherent and fusing myoblasts, as well as triggered lamellipodia, spreading, and fusion of

165 y effect of SFN on HCC tumor angiogenesis as well as tumor growth, and indicate that SFN has potentia

166 ure the proper wiring of neural circuits, as well as windows of vulnerability when abnormal experienc

167 teractions between nCu particles and SRE, as well as with individual organic acids.

168 ausal women with carotid atherosclerosis, as well as with risk of stroke in this population.

169 Baseline demographics were well balanced among the cohorts.

170 level, which allows us to infer the economic well-being of individuals through a measure of their loc

171 of the used devices the median ARD was even well below 10%.

172 sed and therefore may be suboptimal, is less well characterised.

173 e profiling we demonstrate the impact of the well-characterised Shiga toxin-prophage varphi24B on its

174 significant alterations in the expression of well characterized cellular proliferation and apoptosis

175 ugh the canonical Notch signaling pathway is well characterized, accumulating evidence points to the

176 nse in patients with celiac disease has been well characterized, the role of regulatory T (Treg) cell

177 ein methylation on its function has not been well characterized.

178 uman leukocytes to MPLA and LPS has not been well characterized.

179 n, if statistics of the volume variation are well characterized.

180 Here we find that in addition to these well-characterized classes, nearly all of the remaining

181 titutively accumulate greater amounts of two well-characterized defensive compounds, the volatile (E)

182 ngineered and immortalized HEK293 cells with well-characterized electrical properties and the ability

183 ately account for the risks of perchlorate-a well-characterized endocrine-disrupting chemical-to vuln

184 The scope of this review has been limited to well-characterized examples of copper-oxygen species but

185 nics of DNA replication and cell cycling are well-characterized in model organisms, but less is known

186 In a well-characterized mouse model for DM1 (HSALR mice), act

187 Our studies utilized the well-characterized Pax9(-/-) mouse model with a consiste

188 ger in the nearby Universe with a relatively well confined sky position and distance estimate.

189 for the top 20 meters the V S models that is well constrained by the data, we obtain time-lapse repea

190 The proportion of patients with documented well-controlled asthma in this study's primary care popu

191 Given a well-controlled donor/acceptor bilayer system, we uncove

192 Here we present an exceptionally well-dated annual glacial varve chronology recording the

193 Nevertheless, European sites containing well-dated human remains associated with an Acheulean to

194 st plants, but their functions have not been well defined to date.

195 sed by A. baumannii to cause disease are not well defined, but recent research has indicated that sec

196 ses and improve survival for patients is not well defined.

197 ted control of M. tuberculosis have not been well defined.

198 iated inflammatory vascular diseases are not well defined.

199 DH refractory to standard treatments is not well defined.

200 construct simple peptides that assemble into well-defined amyloid phases and define paracrystalline s

201 nd the albumin are independently folded into well-defined domains separated by a flexible linker.

202 cting chemical reaction networks (CRNs) with well-defined dynamic properties.

203 immunoglobulin G (IgG) were fabricated using well-defined full-length antibody-polymer conjugates (AP

204 ce points to the existence of multiple, less well-defined layers of regulation.

205 s of water per day, the water group received well-defined messages about water through counseling and

206 ith orthogonal systems and the generation of well-defined microenvironments can be used to develop no

207 from the vertebral bodies on T2 TIRM images, well-defined paraspinal abnormal contrast enhancement, p

208 x-residue sequence element also turns into a well-defined structural element upon fibril formation.

209 cular, we demonstrate how trapping energy in well-defined train of polarization domain walls allows u

210 In addition, well-designed and -powered studies should be conducted f

211 proving cognitive and depressive outcomes in well-designed studies incorporating comprehensive psychi

212 tologic grade (G1, G2, or G3, for low-grade [well differentiated], intermediate-grade [moderately dif

213 The most rapid and well documented cases of island dwarfing known thus far

214 CBD) and (9)-tetrahydrocannabinol (THC) have well documented immunomodulatory effects in vitro, but n

215 Antarctic surface melt ponds are relatively well documented on some ice shelves, we have discovered

216 strategy by which to target LSCs, with their well-documented heterogeneity and readily evident intra-

217 this chemical cue is preserved in humans as well; E2D induces postural avoidance, increases physiolo

218 ical results are in excellent agreement with well established experimental values when such values ex

219 educed ejection fraction (HFrEF; EF <40%) is well established, but its pathogenic and prognostic sign

220 against reinfection, its pathogenesis is not well established.

221 tures of regulatory T cells (Tregs) are less well established.

222 iated regulation of nucleolar biology is not well established.

223 ency hypothesis by comparing the output of a well-established computational saliency model with the a

224 In this work, we provide an overview of how well-established concepts in the fields of quantum chemi

225 roducibility of published proteomic results, well-established confidence criteria should be reported

226 al therapeutic effects of cortistatin in two well-established preclinical models of atherosclerosis,

227 ressed by the transcription factor Nkx2-1, a well-established suppressor of metastatic progression.

228 with stronger (easier) motion, and they were well fit by a bounded drift-diffusion model.

229 time course of pleasure, across stimuli, is well-fit by a model with one free parameter: pleasure am

230 This is an example of a well-folded partner of NUPR1, because its other interact

231 We show that the resulting model accounts well for puzzling behavioral data on human participants

232 its eight-core CPUs with only 24GB RAM work well in 2017 for these dual segmentation jobs.

233 cantly shallower depths than As contaminated wells in all regions.

234 sily measured but poorly documented gauge of well integrity.

235 chanism of this giant plasmonic resonance is well interpreted by the dispersion of surface plasmon ex

236 the host innate immune system, have not been well investigated.

237 Using two probes, more than 700 well-isolated single neurons were recorded simultaneousl

238 include amyloidogenic peptides, such as the well-known amyloid-beta peptide involved in Alzheimer's

239 or any smoking phenotype, we reconfirmed the well-known CHRNA5-CHRNA3-CHRNB4 genes and further yielde

240 ble to or stronger than the effects of other well-known drivers of productivity, including climate an

241 These well-known drug reservoirs can be used as smart carriers

242 Herbaspirillum rubrisubalbicans is a well-known growth-promoting rhizobacteria that can also

243 tative details about the distribution of the well-known Lewis pairs, such as how they are distributed

244 d electrolyte is demonstrated by modifying a well-known negative photoresist, SU-8, with LiClO4 .

245 , and photoconversion dynamics of Dendra2, a well-known PAFP used in localization microscopy.

246 k luminescence when free in solution or with well matched DNA but exhibits a significant luminescence

247 observations using an analytically solvable, well-mixed approximation.

248 per million (weight/weight), worked equally well on different platforms, exhibited high specificity

249 a strong level of scientific rigor toward a well-planned, step-wise sequence of preclinical and clin

250 t standard population genetic models in fact well predict observed levels of both intra- and interhos

251 The model fits the observed GPP well (R(2) = 0.79), which was confirmed by other model p

252 rs in vascular development within the CNS is well recognized, how these progenitors regulate the vasc

253 use two dimensionality reduction methods as well, robust Principal Component Analysis (PCA) and Isom

254 y have electronic states that are relatively well separated in energy.

255 carbon-based porous nanoarchitectures can be well stabilized in liquids to afford permanent porosity,

256 anism of transcriptional repression has been well studied for over a decade, the DNA-binding activiti

257 features, and trends in their evolution are well studied within the hominin clade.

258 of the innate immune response has been less well studied, although it is key in the clearance of fun

259 in mitochondria is distinct from that in the well-studied nuclear, bacterial, or bacteriophage transc

260 Among these, photochemistry is particularly well suited because these reactions can be performed in

261 calization of genotypes with phenotypes, are well suited for multiplexed single-molecule screening of

262 It is well suited for understanding hypoxia-mediated mechanism

263 attributes also make electrochemical sensors well suited for wearable applications which require exce

264 This platform is robust, scalable, and well-suited for a variety of excitation and readout mech

265 to interpret and easy to compute, making it well-suited for providing standardized, interpretable, a

266 suffer from scalability issues, thus are not well-suited for realistic genome-scale applications.

267 Within these wells, the cells re-aggregated within hours, forming tig

268 s show both good reproducibility and compare well to results from NMR and liquid chromatography-mass

269 tarsudil 0.02% was found to be effective and well tolerated for the treatment of patients with ocular

270 We found that our paradigm is well tolerated in children as young as 6 years, that chi

271 d whether the iron chelator, deferiprone, is well tolerated, able to chelate iron from various brain

272 h doses of SCIg IgPro20 were efficacious and well tolerated, suggesting that SCIg can be used as a ma

273 MSC infusions were well tolerated.

274 Both consolidation therapies were well tolerated.

275 Treatment was generally well tolerated.

276 Repeated infusions of TCZ were well tolerated.

277 of the stem and loop portions were likewise well tolerated.

278 viroc-containing PrEP regimens were safe and well-tolerated compared with TDF-FTC in U.S. women.

279 t SGN-CD19B is pharmacodynamically active at well-tolerated doses.

280 factors regulating target selectivity is not well understood and often overlooked when developing cli

281 thermal transport properties in TMDs are not well understood due to the challenges in characterizing

282 odynamics of coastal marine food webs is not well understood.

283 sphingolipids in differentiated cells is not well understood.

284 ption products within infected cells are not well understood.

285 he mechanism by which bacteria divide is not well understood.

286 umor-infiltrating lymphocytes (TILs) are not well understood.

287 the reason for this gender disparity is not well understood.

288 nce, was observed in Arabidopsis, but is not well understood.

289 the pro-angiogenic effect of IL-37 are less well understood.

290 heir structure under confinement is far less well understood.

291 ntrols vesicle fusion and plasticity are not well understood.

292 ation of morphogenic signals by cells is not well understood.

293 erplasia (BPH), the etiology of which is not well understood.

294 s of carotenoid uptake and transport are not well-understood.

295 for ICU refusal in patients considered "too well" were advanced age, male sex, university hospital a

296 n-orbit coupling in In0.75 Ga0.25 As quantum wells, which indeed can be tuned by the indium compositi

297 Results on real data agree well with current knowledge.

298 Its dynamic CO2 uptake also matched well with its static condition.

299 This agrees well with the calculated tumor control probability.

300 Measured spectra agreed well with those predicted.

301 as a footprint of only 3.8 x 2.5 mum, and is well within the design rules of a typical silicon photon