ライフサイエンスコーパス: well-defined

1 ver, factors regulating this process are not well defined.

2 ntigen-specific T cells in vivo has not been well defined.

3 ading to immunosuppression in sepsis are not well defined.

4 ted control of M. tuberculosis have not been well defined.

5 eavage by the gamma-secretase complex is not well defined.

6 iated inflammatory vascular diseases are not well defined.

7 der adults; however, the relationship is not well defined.

8 clinical features of the disease may not be well defined.

9 ty and its impact on gene expression are not well defined.

10 CRC such as the NLR, PLR, and mGPS has been well defined.

11 DH refractory to standard treatments is not well defined.

12 enetic testing in non-BRCA mutations are not well defined.

13 consumers, and quality of care have not been well defined.

14 ast milk of HCMV-seropositive mothers is not well defined.

15 k of NC in these patients has still not been well defined.

16 le inflammation and oncogenesis has not been well defined.

17 and cellular sources regulating this are not well defined.

18 munocompromised patients without HIV is less well defined.

19 opulation, the underlying mechanisms are not well defined.

20 adigms akin to degenerative disease-are less well defined.

21 outcomes and modifiable risk factors are not well defined.

22 ing agonist-induced ASMC contraction are not well defined.

23 he time as measured by a single clock is not well defined.

24 tream, but their survival mechanisms are not well defined.

25 phenotype and tumorigenesis in TNBC are not well defined.

26 of age on surveillance outcomes has not been well defined.

27 gene hereditary cancer testing panels is not well defined.

28 ycemia accelerates lesion development is not well defined.

29 trols inflammation versus cell death is less well defined.

30 sis, posttranscriptional mechanisms are less well defined.

31 Ig isotype influences B cell behavior is not well defined.

32 a protein's amino acid sequence is still not well defined.

33 are lacking, and prognostic factors are not well defined.

34 l systems its mechanistic basis has not been well defined.

35 virus recognition and immunogenicity is not well defined.

36 id antigens encountered by iNKT cells is not well defined.

37 apoptosis to GC biology and selection is not well defined.

38 that promote and sustain autophagy are less well defined.

39 HIV-1 pathogenesis, their mechanisms are not well defined.

40 ng network is cortically (i.e., gray matter) well defined.

41 es, such as coronary atherosclerosis, is not well defined.

42 he selective forces influencing this are not well defined.

43 pment, as well as in disease states, are not well defined.

44 lar players involved in this process are not well defined.

45 ses and improve survival for patients is not well defined.

46 f the innate immune system are currently not well defined.

47 ssociations to guide future behavior is less well-defined.

48 e of antigen-specific CD4(+) T cells are not well-defined.

49 tracellular serotonin levels in vivo are not well-defined.

50 ediate tissue repair and fibrogenesis is not well-defined.

51 the underlying molecular mechanisms are not well-defined.

52 e in carbon-metal bond cleavage has not been well-defined.

53 (and compositions in the vicinity) exhibits well-defined 1:3 charge order of Mn(4+) and Mn(3+) and o

54 A well-defined 3D structured gold nanoarray was fabricated

55 In brief, miRNAs usually have a well-defined 5' end and a more flexible 3' end with the

56 rate shows an Arrhenius dependence with two well-defined activation energies of 73 +/- 5 meV and 420

57 adhesion of connective tissue cells through well-defined adhesion platforms.

58 Finally, imaging neurons of a well-defined adult motor circuit, we found that reversal

59 utilize chiral reagents that form discrete, well-defined aggregates with lithium enolates, providing

60 iazabicyclo[4.4.0]dec-5-ene (TBD) to yield a well-defined, alkene-substituted degradable polymer, whi

61 construct simple peptides that assemble into well-defined amyloid phases and define paracrystalline s

62 Critically, these visual maps constitute well-defined anatomical units that future studies of fro

63 However, the effect of SLD has not been well defined and no tool has been developed to estimate

64 of the CYP3A4-MDZ complex, where the drug is well defined and oriented suitably for hydroxylation of

65 Medical indications for mastectomy are well defined and present in a minority of patients, and

66 the time required for such communication is well defined and preserved.

67 e in hypoxia-induced excitation is still not well defined and remains controversial.

68 aracterized by cyclic voltammetry and showed well defined and reversible Fe(+)/ Fe(3+) redox couple a

69 While many species already have a well-defined and characterized miRNAome, miRNAs have not

70 e entities interact over long distances in a well-defined and controllable manner are valuable so tha

71 e to discriminate clearly between clinically well-defined and homogeneous postcardiopulmonary bypass

72 ts were used as a model, which constitutes a well-defined and homogenous sample matrix with simple ce

73 ification of the sensing layer resulted in a well-defined and stable square-wave voltammogram of the

74 underlying DNA sequences have been much less well defined, and existing methodologies for studying ce

75 Readily available, well-defined, and air-stable 1 catalyzes the challenging

76 opportunity for quick and easy production of well-defined antibody conjugates from a variety of antib

77 ell as the construction of covalently linked well-defined architectures thereof, e.g. block copolymer

78 These structurally well-defined, asymmetric membranes facilitate control ov

79 Here we report the discovery of well-defined Au(III) complexes that participate in rapid

80 Myeloperoxidase (MPO) is a well defined autoantigen in ANCA-associated vasculitis.

81 both processes shapes the auxin profile in a well-defined auxin minimum.

82 quid picture of long-lived quasiparticles in well-defined band states emerge at low temperatures near

83 silica support (SiO2-700) to synthesize the well-defined bimetallic precatalyst [( identical withSi-

84 moderate temperature (150 degrees C) using a well-defined bimetallic system prepared via the SOMC app

85 The first example of a well-defined binary, low-oxidation-state aluminum hydrid

86 lack of suitable screening methodologies and well-defined binding pockets on the Ras proteins.

87 knowledge can be used for the development of well-defined bioactive coatings, biosensors and biomimet

88 ser treatment, whereas those with smooth and well-defined borders of the coast of California subtype

89 located in the mid or far periphery and had well-defined borders, resembling congenital hypertrophy

90 sitides and GTP-bound GTPases, which provide well-defined but mutable labels.

91 sed by A. baumannii to cause disease are not well defined, but recent research has indicated that sec

92 r this major subfamily of TRP channels and a well-defined calcium-binding site within the intracellul

93 ing in empirical evidence from NGS data that well-defined carcinogen mutational signatures are indeed

94 Peptide sequences derived from the well-defined CARM1 substrate poly(A)-binding protein 1 (

95 antioselective transformation catalyzed by a well-defined cationic gold(III) catalyst and demonstrate

96 eal a highly organized array of discrete and well-defined cavities that are suitable for hosting gues

97 an be used to explore collective dynamics in well-defined cell networks is still very limited.

98 ouse and human is reliant on the presence of well-defined cell surface markers specific for diverse p

99 ngth of e ach displacement evolves to show a well-defined characteristic scale that is not found in n

100 such function has been hampered by a lack of well-defined characteristics that can identify granule c

101 aminographene, graphene acid pose unique and well defined chemical and physical properties, allowing

102 , having well-defined chemical structure and well-defined chemical bonds, are of a great interest to

103 oichiometric derivatives of graphene, having well-defined chemical structure and well-defined chemica

104 pplication of wholly synthetic networks with well-defined chemistries and interactions.

105 Xandarellida is a well-defined clade of Lower Palaeozoic non-biomineralize

106 ing are found, once fully mapped, to lead to well-defined classes of connectivity.

107 Urine specimens from a well-defined cohort of HIV-infected South African adults

108 re released in quantitative yield along with well-defined, colorless hydroquinone byproducts.

109 e NMR spectroscopic investigations show that well-defined complex 3b (alpha-diimine)Ni(Me)(OEt2)(+) r

110 ess in glycoscience is hampered by a lack of well-defined complex oligosaccharide standards that are

111 s or giant unilamellar vesicles (GUVs) under well-defined concentrations of AMPs and fluorescent mole

112 ased disease risk (Arg299:Ser306) exhibits a well-defined conformation and higher positive surface ch

113 We observe a single well-defined conformation that is folded toward the surf

114 ule folds, it often does not adopt a single, well-defined conformation.

115 In this study, a photoresist template with well-defined contact hole array was fabricated, to which

116 "off" state and a fluorescent "on" state at well-defined coordinates on subdiffraction scales.

117 instead of brick-shaped mature virions with well-defined core structures.

118 Yet, the synthesis of structurally well-defined, core-fucosylated glycoproteins remains a c

119 ocesses that produce standardized cells with well-defined critical quality attributes appropriate for

120 eno[1,2-b]fluorene to produce molecules with well-defined cruciform topologies, extended pi-conjugate

121 yered 2D frameworks (C3 N and C2 N-450) with well-defined crystal structures are explored for use as

122 applied bias is varied, the device exhibits well-defined cut-off wavelengths of either approximately

123 ble polycarbonate track etched supports with well-defined cylindrical approximately 200 nm pores.

124 Here we infer the potential impact of 19 well-defined DCAFs in human lung adenocarcinomas (LuADCs

125 We present the first well-defined degradable poly(phosphonate)s with adjustab

126 mal gradients in fluid systems with initial, well-defined density gradients results in the formation

127 overage metabolomic profiling has revealed a well-defined development of metabolic decay in human red

128 integration of clonal columns determines the well-defined diameter and resulting rod-like morphology.

129 studies of WSe2-WS2 lateral junctions showed well-defined diode characteristics with a rectification

130 ional spectral weight, longer lifetimes, and well-defined dispersions.

131 etically place a spin-laden propyl moiety at well-defined distances from an electronic spin center by

132 such a prior, an encoding model specifies a well-defined distribution of activity profiles.

133 his study reports an intriguing example of a well-defined, DNA-catalyzed, radical reaction process th

134 nd the albumin are independently folded into well-defined domains separated by a flexible linker.

135 cting chemical reaction networks (CRNs) with well-defined dynamic properties.

136 Measurements of soft hydrogel samples with a well-defined elastic modulus using different AFMs reveal

137 The structure revealed a well defined electron density for p261C and the phosphod

138 ties at high temperatures imply that neither well-defined electron nor phonon quasiparticles are pres

139 ural changes, even in isotropic samples when well-defined electronic transitions are excited.

140 eat allergy (WA) and celiac disease (CD) are well-defined entities, but are becoming a fraction of in

141 activities of such species in controlled and well-defined environments.

142 ion in an in vivo model of TCD8 responses to well-defined epitopes of a clinically relevant oncoprote

143 d Early Paleoindians represents the earliest well-defined evidence of humans in Pleistocene North Ame

144 ontrol the reactivity of these reactions are well-defined experimentally, but the mechanistic details

145 f CuI on the NC surface, which is favored on well-defined facets of larger NCs.

146 as optical absorption and emission, showing well-defined features, just like molecules.

147 ticross-linked proteins with predictable and well-defined folds, including ones not found in nature.

148 proach to managing acid-base balance is less well defined for patients receiving hemodialysis than fo

149 e dimer, then one can assume that there is a well-defined free energy well around the native state, w

150 immunoglobulin G (IgG) were fabricated using well-defined full-length antibody-polymer conjugates (AP

151 strategies that permit long-lived display of well-defined, functionally active molecules are highly a

152 Well-defined, fused-ring aromatic oligomers represent pr

153 o profile the interaction proteomes of three well-defined G4 structures derived from the human telome

154 d by nature, we here theoretically show that well-defined gate shape, sensitive response to pH and sa

155 Infectious HCV epitope mutants encoding the well-defined genotype 1a-derived HLA-A2-restricted HCV N

156 understanding the spectra of particles with well-defined geometries, we report here on samples that

157 e separation distance and stoichiometry, and well-defined geometry, can be used as excellent substrat

158 monoclonal and two polyclonal antibodies to well-defined gluten protein types (GPT) isolated from wh

159 heet were then synthesized and shown to form well-defined helix-turn-helix architectures in which hel

160 The well-defined heterobimetallic hydride complexes act as p

161 On ultrasound, there were well-defined, heterogeneous, predominantly hypoechoic, r

162 ial carbonyl groups, resulting in atomically well-defined heterojunctions within a single GNR.

163 osits in the elderly brain generally display well-defined hierarchical cortical relationships as well

164 xploited to generate and dynamically control well-defined higher-order (secondary) conformations of t

165 nctionalized cinnamate ligands, allowing for well-defined, highly tunable chemical systems.

166 ange 20-84 years, median 61.06 years) with 4 well defined histological conditions: 20 controls with h

167 This method provides well-defined homopolymers, diblock copolymers, and biohy

168 (1,800 cells/mm(2) ) area embedded within a well-defined horizontal visual streak (800 cells/mm(2) )

169 dology that can rapidly provide a library of well-defined HS oligosaccharides.

170 The development of porous well-defined hybrid materials (e.g., metal-organic frame

171 A well-defined hydride Mn(I) PNP pincer complex, recently

172 2-methylene-1,3-dioxepane (BMDO), results in well-defined, hydrolytically degradable polymers, as con

173 Dye angiography demonstrated a well-defined hyperfluorescent lesion with variable leaka

174 stablish and regulate pluripotency have been well defined in the mouse, it has been difficult to extr

175 phic-based DR grading, follow-up visits, and well-defined incident CVD end point.

176 In addition to its well-defined interaction with nuclear pore complexes, he

177 et chemistry method is employed to fabricate well-defined iron oxy-hydroxides and transitional metal

178 ons closely resembled Lgr5(+) ISCs, the most well-defined ISC pool, but Bmi1-GFP(+) cells were distin

179 es in which the knots are not mathematically well defined; knotting can only be identified by closing

180 Here, we observe unusually well-defined Kondo resonances in magnetic molecules sepa

181 mposition and function of VLVs have not been well defined, largely due to the inability to efficientl

182 long-range periodicity in all dimensions and well-defined lattice orientation.Conventional fabricatio

183 ce points to the existence of multiple, less well-defined layers of regulation.

184 generate limiting scissioned fibrils with a well-defined length-to-width correlation for the mutant

185 Here, we use well-defined ligand-protected perovskite nanocrystals (N

186 t domains separated by a short, structurally well-defined linker.

187 have also been shown to bind cholesterol at well-defined locations on their membrane-facing surface.

188 cts would benefit from convenient sources of well defined, low cost, food-grade maltooligosaccharides

189 lows domain walls to pin with consistent and well-defined magnetisation configurations, thus suppress

190 ctively modulate the dynamics of the ER in a well-defined manner, which is expected in turn to impact

191 erization of these monomer families to yield well-defined materials over a range of molecular weights

192 aMnAs film with two in-plane easy axes shows well-defined maxima and minima that can serve as two bin

193 ending device which is capable of delivering well-defined mechanical loads to metatarsal bones of liv

194 compounds can be engineered to have several well-defined mechanical states by incorporating recognit

195 With their well-defined mechanism of action and high proteomic spec

196 we use patterned nanostructures to generate well-defined membrane curvatures ranging from +50 nm to

197 s of water per day, the water group received well-defined messages about water through counseling and

198 ication of alternating spin-coated layers of well-defined metal polypyridyl complexes and a palladium

199 al and achiral model surfaces, especially on well-defined metal single crystals but also on other fla

200 Fundamental studies of well-defined metal surfaces using a variety of technique

201 ith orthogonal systems and the generation of well-defined microenvironments can be used to develop no

202 Six adults in a well-defined mitochondrial disease cohort and 11 additio

203 l low-lying Kramers doublets correspond to a well-defined MJ value, with no significant mixing even i

204 Initial experiments on water oxidation by well-defined molecular catalysts were initiated with the

205 Self-assembly of the reactants in well-defined molecular domains prior to reaction could g

206 ticles (NPs), leading to bimetallic NPs with well-defined molecular formula and atomically-controlled

207 is possibility inspires the investigation of well-defined molecular iron hydrides as precursors for c

208 In these systems, reactivity occurs at well-defined molecular transition metal active sites, an

209 s without optimized shapes can robustly form well-defined morphologies.

210 ultrafast photoinduced electron transfer in well-defined multichromophoric structures are indispensa

211 We show that the non-existence of well-defined multiorbital correlation clustering provide

212 sulting triazoles were quaternized providing well-defined multitriazolium platforms.

213 iple building blocks via hydrogen bonds into well-defined nanoconstructs with selective binding funct

214 Through the use of well-defined nanocrystals as seeds, including those with

215 In this work, a well-defined nanographene-Re complex was synthesized, in

216 rystal Hotel" microfluidic device to provide well-defined, nanoliter volumes, we observed that calcit

217 Novel UF hollow fiber membranes with well-defined nanopores and surface charges were develope

218 ance of the cytosensor was attributed to the well-defined nanostructure and biocompability of PNPs on

219 es, offer a versatile platform for preparing well-defined nanostructures wherein functionality such a

220 n the early postnatal period by activating a well-defined neurodevelopmental disease pathway and that

221 s should be on the basis of an evaluation of well-defined neurological outcomes that are ascertained

222 Here we investigate well-defined, non-spherical evaporating drops of pure li

223 By enabling the transfer of a well-defined number of charge carriers between the islan

224 uires interaction with multiple lipids and a well-defined orientation on the membrane, resulting in a

225 from the vertebral bodies on T2 TIRM images, well-defined paraspinal abnormal contrast enhancement, p

226 in a single direction, outlining for them a well-defined pathway.

227 A well-defined Pd(II)-peroxo complex is a competent interm

228 ical (plasmonic) properties of an atomically well-defined Pd(sub-monolayer)/Au(111) bimetallic model

229 This sensor shows separated and well-defined peaks for A and G, by which one can determi

230 Our study focused on the intriguing well-defined pelagic methane enriched zone (PMEZ) in fre

231 A strategy to deliver a well-defined persulfide species in a biological medium i

232 tiple benzothiadiazole units are attached to well-defined planar and nonplanar molecular cores.

233 s of C60 were bound anticooperatively within well-defined pockets; an X-ray crystal structure of thre

234 s that allow a reaction to be initiated at a well-defined point in time and space.

235 in living radical polymerization, yielding a well-defined polymer-iodide.

236 e water-soluble block can self-assemble into well-defined polymersomes with narrow size distribution.

237 C differ, few have compared them directly in well-defined population samples.

238 n for human NSCs in adult injured CNS is not well defined, posing fundamental questions about the des

239 ssociated with poor outcome independently of well-defined prognostic factors in neuroblastoma, breast

240 majority of them lie outside of functionally well-defined protein coding regions.

241 for which the GEF activity was ascribed to a well-defined protein sequence that directly binds Galpha

242 Because in this structurally well-defined protein the distances between bacteriochlor

243 sensor system, we successfully detected four well-defined pulmonary hypertension-associated biomarker

244 or transition-metal-catalyzed reactions with well-defined reaction mechanisms but multiple stereocont

245 ase immobilized GR and CMF modified SPCEs, a well-defined redox couple of Cu(I)/Cu(II) for laccase wa

246 A pair of well-defined redox waves in neutral pH solution due to e

247 Over well-defined regions of North America, there are general

248 have undertaken a comprehensive analysis of well-defined regions of secondary cell wall CESA protein

249 There is a well-defined regulatory framework governing the approval

250 ts where electrocardiogram T waves involve a well-defined repolarization edge traversing the epicardi

251 A well-defined risk factor and precursor for cutaneous mel

252 Besides its well defined role in innate immunity, aberrant degranula

253 TP channels in vascular smooth muscle have a well-defined role in regulating vascular tone.

254 the community and researchers have specific, well-defined roles as part of an equitable partnership t

255 inward-opening, and identifies diverse, yet well-defined roles for different Na(+)-coordinating resi

256 Neuropilins (NRPs), which have well-defined roles in Semaphorin and VEGF signaling, pos

257 Many foldamers, oligomers that adopt well-defined secondary structures, are now known, includ

258 quired for SNARE complex assembly, implies a well-defined sequence of events coordinating K(+) uptake

259 Based on a narrow and well-defined set of parameters, our approach results in

260 the ability to prepare PLLA assemblies with well-defined shape and dimensions is limited and represe

261 lic nanocrystals with controllable sizes and well-defined shapes is highlighted.

262 The well-defined silica-supported molybdenum oxo alkyl speci

263 tion of very closely related isolates from a well-defined single-source campylobacteriosis outbreak.

264 The extent of rod saturation is not well defined; some studies report rod activity well into

265 nse variables) of a seagrass assemblage with well-defined species interactions to ocean acidification

266 d channel activity was observed to have both well-defined "square top" openings as well as fast curre

267 Artificial synthetic molecules able to adopt well-defined stable secondary structures comparable to t

268 Reprogramming is a stepwise process with well-defined stages of initiation, maturation and stabil

269 ence data, we identified a set of reads with well-defined start and stop positions, in a length range

270 nthetic consortia with safe and functionally well-defined strains.

271 x-residue sequence element also turns into a well-defined structural element upon fibril formation.

272 With the well-defined structure and manual curation, Gene Ontolog

273 lata B1 backbone scaffold, together with the well-defined structure of the cyclotide, allowed us to c

274 e branched, multivalent nanoparticles with a well-defined structure that have a high potential for bi

275 Rather than forming a well-defined structure, FtsZ protofilaments laterally as

276 for all of them, with a very interesting and well-defined structure-activity relationship.

277 e at least five consecutive residues without well-defined structure.

278 TA fragments have also found applications as well-defined synthetic antigens for the generation of no

279 the last fifteen years, many combinations of well-defined systems involving different kinds of metals

280 ation and incomplete lineage sorting obscure well-defined taxonomic lineages.

281 Although gut microbiome composition is well defined, the mechanisms underlying community assemb

282 Although the language network is cortically well defined, the role of the white matter pathways supp

283 While the role of HA in malignancy is well-defined, the mechanisms driving its biosynthesis in

284 2X receptors, the P2X7 receptor (P2X7R) is a well-defined therapeutic target for inflammatory and neu

285 d cellular pathways triggering arthritis are well defined, those responsible for the resolution of in

286 s (IDPs) are functional proteins that lack a well-defined three-dimensional structure.

287 or regions that exist and function without a well-defined three-dimensional structure.

288 and highly tunable hybrid nanomolecules with well-defined three-dimensionality.

289 termolecular interaction strengths exceeds a well-defined threshold.

290 The photon is re-emitted at a well-defined time due to an interference effect analogou

291 st plants, but their functions have not been well defined to date.

292 cular, we demonstrate how trapping energy in well-defined train of polarization domain walls allows u

293 We examined the role of serotonin on well-defined tuning properties (orientation, spatial fre

294 nt called the polarization; materials with a well-defined uniform polarization display a dramatic ran

295 o be convincingly demonstrated by a range of well-defined users.

296 macrocyclic molecules that exhibit a single well-defined voltage profile-compared to the discrete mu

297 s to disrupt the membranes of cells within a well-defined volume.

298 function of the infant gut microbiota is not well defined.We sought to determine the effects of a bif

299 odel compounds has shown the fractions to be well-defined, with classes of model compounds isolated w

300 hly unstable Ta(CO)6 and represents the only well-defined zerovalent tantalum complex to be prepared