ライフサイエンスコーパス: well-established

1 ement in color stabilization in red wine are well established.

2 to control reaction selectivity has not been well established.

3 av1.3 in neuropsychiatric phenotypes are not well established.

4 field on excitable cells such as neurons are well established.

5 rs, but its use in cryptogenic stroke is not well established.

6 comes of P. aeruginosa infections is not yet well established.

7 role of PXR as a xenobiotic sensor has been well established.

8 d better outcomes for surgical procedures is well established.

9 ous coronary intervention (PCI) has not been well established.

10 such as myocardial infarction and stroke is well established.

11 rs, but an oncogenic role for SWI/SNF is not well established.

12 hing with kidney allograft survival has been well established.

13 ium-zinc-telluride (CZT) SPECT camera is not well established.

14 on perception of threshold-level stimuli is well established.

15 rt study in England, where such services are well established.

16 whose identity and role in the heart are not well established.

17 on and peripheral insulin resistance (IR) is well established.

18 omy to preserve kidney function has not been well established.

19 its effect on oxygen storage capacity is not well established.

20 components involved in this process are not well established.

21 D, although an etiologic role in PDNS is not well established.

22 that obey the Michaelis-Menten equation are well established.

23 ing Autism Spectrum Disorder (ASD), has been well established.

24 pendent DNA damage response (DDR) pathway is well established.

25 le in gene transcription modulation has been well established.

26 d functional properties have been relatively well established.

27 t dietary policies on CVD disparities is not well established.

28 nal role of RavA-ViaA in the cell is not yet well established.

29 against reinfection, its pathogenesis is not well established.

30 eases, but the underlying mechanisms are not well established.

31 y be dietary in origin; however, this is not well established.

32 on ongoing neural activity in humans is not well established.

33 tures of regulatory T cells (Tregs) are less well established.

34 tion and its functional consequences are not well established.

35 of mTORC2, the role of Rictor in T cells is well established.

36 achieved after treatment initiation is less well established.

37 iated regulation of nucleolar biology is not well established.

38 f glycated proteome has been relatively less well established.

39 ic variation on gene expression in humans is well-established.

40 though the role for surgical intervention is well established, a clear trend toward less-aggressive,

41 ion in adult kidney transplant recipients is well established, a similar benefit in pediatric recipie

42 d perinatal morbidity and mortality, and the well-established accuracy of blood pressure measurements

43 yr BP, yet a well-established agrarian society does not appear in the

44 process that serves as a surrogate for other well-established alkyne syntheses.

45 al of the rISFV vector was investigated in a well-established alphavirus disease model.

46 rticularly edge-to-edge leaflet repair, is a well-established alternative for patients with severe pr

47 ed maximum likelihood estimation (TMLE) is a well-established alternative method with desirable stati

48 and neurodevelopmental defects in progeny is well established, although the biological mechanisms and

49 mography tracer 18F-AV-1451) associated with well-established Alzheimer's disease factors in a cohort

50 nea, where limbal stem cell concept has been well established and accepted.

51 management best practices should be based on well established and emerging scientific understanding o

52 Ion mobility (IM) is now a well-established and fast analytical technique.

53 ncing fastq files as input, calls on several well-established and freely available genome-analysis to

54 Well-established and new techniques of cardiac imaging a

55 In addition to both well-established and newer MSM methods, the package incl

56 rough a nanochannelled device validated with well-established and newly developed reprogramming model

57 evidence has been provided to undermine the well-established and physically plausible consensus that

58 otential mechanical explanations for several well-established and recently discovered cytoprotective

59 he use of these new powerful technologies in well-established and uncharacterized translation-depende

60 ations; computational theories of vision are well established, and empirical protocols for measuring

61 F, including stroke and thromboembolism, are well established, and epidemiology studies have champion

62 e of histone acetylation in plant defense is well established, and it is known that pathogen effector

63 in regions where Mesolithic populations were well established; and a third corresponding to large-sca

64 Doxorubicin is a highly efficacious and well-established anthracycline chemotherapeutic agent co

65 ur findings imply that, in addition to their well-established antimicrobial properties, neutrophils c

66 Gap junction remodeling is well established as a consistent feature of human heart

67 Cell-penetrating peptides (CPPs) are well established as delivery agents for otherwise cell-i

68 Fragment-based drug discovery (FBDD) is now well-established as a technology for generating new chem

69 ge qPCR assays perform at a similar level to well-established bacterial human-associated fecal-source

70 Outcomes of CRT-D in these patients are not well-established because they have been underrepresented

71 r findings provide a novel mechanism for the well-established beneficial cardiovascular effects of TA

72 s, is relatively simple and complementary to well-established biophysical approaches.

73 Game theory is a well established branch of mathematics whose formalism h

74 ents in visual and acoustic communication is well established, but comparable information on chemical

75 educed ejection fraction (HFrEF; EF <40%) is well established, but its pathogenic and prognostic sign

76 zard plastic debris poses to biodiversity is well established, but mitigation and planning are often

77 responses of SCN neurons to light steps are well established, but responses to more natural modulati

78 ship between dinosaurs and other reptiles is well established, but the sequence of acquisition of din

79 Wnt, and BMP at the neural plate border are well established, but the signals required for subsequen

80 ding metabolites to support tumour growth is well-established, but the involvement of glutamine metab

81 It is now well established by numerous experimental and computatio

82 ey pfsSNVs within 17 genes that are found in well-established cancer associated gene lists.

83 ive, proliferative or survival assessment of well-established cancer models and clinically relevant p

84 esis, we employed the growing pollen tube, a well-established cell polarity model system, and perform

85 the currently utilized fossil-based ones in well-established chemical processes.

86 Besides the well-established chirality transfer from bioorganic mole

87 Among African Americans from 2 large, well-established cohorts, participants with SCT had lowe

88 0 analytic tool descriptions integrated from well-established, community repositories.

89 Main Outcome and Measures: A well-established computational model captured effects of

90 ency hypothesis by comparing the output of a well-established computational saliency model with the a

91 dback on hypothalamo-pituitary function is a well-established concept, the present study shows that n

92 In this work, we provide an overview of how well-established concepts in the fields of quantum chemi

93 roducibility of published proteomic results, well-established confidence criteria should be reported

94 on and its associated adherens junctions are well-established contributors to mechanosensing and tran

95 hough peptide synthesis and modification are well established, controlling quaternary structure forma

96 Beclin 1 is a well-established core mammalian autophagy protein that i

97 Wiener-Granger causality approach along with well-established cross-correlation analysis to investiga

98 The 'grooming handclasp' is one of the most well-established cultural traditions in chimpanzees.

99 ng properties of anti-MAG autoantibodies are well established, current treatments are aimed at reduci

100 nically relevant cases were identified using well-established cutoffs; daily PM2.5 estimates were obt

101 ion rates further by identifying gaps in the well-established donation after circulatory death proces

102 Because of its well established dopaminotrophic effects, the therapeuti

103 Type-2 immune responses are well-established drivers of chronic inflammatory disease

104 Moxidectin, a well-established drug in veterinary medicine under consi

105 follow the Hofmeister series, but unlike the well-established effects on the stability of folded prot

106 ured interprofessional rounding script and a well-established electronic health record, clinician lab

107 could not be drawn because of the lack of a well-established elevation threshold; however, higher in

108 Despite well-established evidence that cigarette smoking is the

109 ical results are in excellent agreement with well established experimental values when such values ex

110 ce recovery after photobleaching (FRAP) is a well-established experimental technique to study binding

111 Despite the existence of well-established experimental techniques such as photoco

112 and Helvetic Marl (HM), was studied using a well-established experimental through-diffusion techniqu

113 tracking offers several advantages over the well-established eye coil and video-oculography methods.

114 A well-established fermentation strategy is available comp

115 from a largely hypothetical possibility to a well-established field that can be applied to the reduct

116 EigenTHREADER outperforms well-established fold recognition methods such as pGenTH

117 FRET and BRET approaches are well established for detecting ligand induced GPCR-G pro

118 ded for sulfate-bearing minerals but is less well established for pyrite-based records.

119 ale quantitative epistasis analysis has been well established for single cells.

120 Although both strategies are well established for these two different age groups and

121 Using a well established forward-modeling scheme, we investigate

122 player in inflammatory disorders besides its well-established function as tumour suppressor.

123 t abundant tegument proteins of HSV-1, but a well-established function has yet to be found.

124 Apart from their well-established function in action potential propagatio

125 A well-established function of intercellular connectivity

126 Growth Factor (PDGF) family of ligands have well established functions in the induction of cell prol

127 intenance in Arabidopsis are controlled by a well-established gene network revolving around the key r

128 We address this by: 1) exploiting well-established graphlet measures via a new network ali

129 Cognitive stimulation therapy (CST) is a well-established group psychosocial intervention for peo

130 In a well-established guinea pig model of aerosol infection w

131 Using a well-established HEK cell biosensor assay, we show that

132 HFpEF, partially attributable to the lack of well-established HFpEF animal models.

133 these findings to normal mice observing the well-established histamine model of acute itch in demons

134 ale serological screening studies focused on well-established HNVs.

135 ic synapses with certain RGCs, but it is not well established how many types receive this direct AII

136 complexes that coordinate the heartbeat are well established, how the heart maintains its electromec

137 While systems to manage reductive stress are well-established, how cells cope with an overly oxidizin

138 ts of particulate matter on human health are well established however the effects on bacteria, organi

139 Nickel compounds are well-established human carcinogens that induce tumorigen

140 tionale, we encapsulated microRNA-34a in our well-established Hyaluronic-Acid nanoparticles and deliv

141 utations in pediatric glioblastoma and their well-established impact on global histone H3 lysine 27 d

142 Given the well-established importance of microRNAs (miRNAs) in neu

143 ite populations, but its significance is not well established in African Americans persons whose card

144 ge (WPND) has continued to spread and is now well established in all New England states.

145 the cause of pneumonia in adults but is less well established in children.

146 sity and breast cancer risk and prognosis is well established in estrogen receptor (ER)-positive dise

147 ative role of alpha-synuclein (alpha-syn) is well established in Parkinson's disease pathogenesis, av

148 Although haploid selection is well established in plants, current dogma assumes that i

149 ation of cAMP levels by phosphodiesterase is well-established in eukaryotic cells.

150 tive to the Pacific coast of Asia, it is now well-established in North America and Europe, where its

151 The chemistry of sapphyrins has been well-established in recent years due to the availability

152 eed for action-contingent visual feedback is well-established in the developmental literature.

153 -assembly of predesigned building blocks are well-established in the literature, but spontaneous self

154 We also show that a well-established in vivo mild chronic hypoxia (MCH) mous

155 ncludes a training process on 985 genes with well-established inheritance patterns for Mendelian cond

156 While aminoadamantanes are well-established inhibitors of the influenza A M2 proton

157 on, unraveling a new mechanism mediating the well-established interactions between endogenous opioids

158 olcanic forcing, and climate as reflected in well-established Intertropical Convergence Zone (ITCZ) r

159 ithelial ovarian cancer (EOC) was considered well established, investigators in recent studies includ

160 s of innate control of adaptive immunity are well established, it is not fully understood how innate

161 h the value of liver transplantation (LT) is well established, its place in the management of HEHE is

162 cking tumor growth by targeting autophagy is well established, its role on the infiltration of natura

163 in vitro studies regarding the effect of the well-established L-type calcium channel antagonist nimod

164 Here, 79 healthy females completed a well established laboratory procedure of acute stress in

165 der environmental conditions and the lack of well-established large-area synthesis protocols hinder i

166 of functional connectivity within and across well-established large-scale brain networks can be consi

167 dopamine in learning from choice outcomes is well established, less is known about its role in learni

168 imb musculature in performing these tasks is well established, less research has focused on the muscl

169 Without well-established listing guidelines, SLKT potentially wa

170 However, LMICs do not have well-established, low-technology ways to quantify and co

171 ines in normal and malignant cell biology is well established, many of the molecular mechanisms regul

172 g glioblastoma (GBM), and is considered as a well-established marker for tumor metastasis and recurre

173 These data informed changes in our well-established mathematical model of the rabbit myocyt

174 ded RNA (ssRNA) viruses but differs from the well-established mechanism of pumping dsDNA into a prefo

175 g-range transport mechanism comparing to the well-established mechanism, with long-range transport mo

176 he same time, many of the genes encoding for well-established meiotic and post-meiotic proteins are a

177 -density lipoprotein cholesterol(LDL-C) is a well established metabolic marker of cardiovascular risk

178 However, no well-established method exists to measure solute partiti

179 tively coupled plasma mass spectrometry is a well-established method to resolve cell-associated (meta

180 Nevertheless, these well-established methods have only been applied in prima

181 The adult zebrafish is a well-established model for studying heart regeneration,

182 The honeybee olfactory system is a well-established model for understanding functional mech

183 In a well-established model of allergic contact dermatitis, t

184 tment ameliorated hepatocellular injury in a well-established model of liver partial warm ischemia an

185 he underlying mechanisms by inducing MI in a well-established model of T2DM and control mice.

186 onal analysis of RNA folding can make use of well-established models of the thermodynamics of RNA str

187 ronic administration of lithium, a drug with well established mood-stabilizing effect in humans with

188 Using a well-established mouse model of prenatal viral-like immu

189 We assess their in vivo bioactivity in a well-established mouse model of psoriasis, the KC-Tie2 m

190 lating antiviral cytokine responses has been well established, much less is known about their involve

191 This was associated with the absence of a well-established multisensory effect (visual enhancement

192 ar herpesvirus infection and disease using a well-established murine model in which HSV-1 reactivatio

193 ohort of HCV Infected Veterans (ERCHIVES), a well-established national cohort of HCV-infected Veteran

194 The well-established negative health outcomes of sleep depri

195 Most well established neglected tropical disease (NTD) progra

196 METHODS AND We applied a well-established network biology approach (master regula

197 nic region-an Antarctic greening to parallel well-established observations in the Arctic [20].

198 rule-guided prosaccades and antisaccades, a well established oculomotor task for testing cognitive c

199 The most well established of these are the blood eosinophil count

200 Biolayer interferometry (BLI) is a well-established optical label-free technique to study b

201 -performance in-memory implementation of the well-established over-representation analysis method.

202 Drosophila segmentation is a well-established paradigm for developmental pattern form

203 ated oxidation of SO2 outcompetes with other well-established pathways.

204 ulosa cells of PCOS patients as well as in a well-established PCOS mouse model.

205 role of pertussis toxin in whooping cough is well-established, pertussis-like toxins produced by othe

206 The well established phenomenon of ribosome drop-off plays c

207 GPCR dimerization is a well-established phenomenon that can alter protomer func

208 oelastic' response of confined aquifers is a well-established phenomenon which has been demonstrated

209 cupation in optically excited materials is a well-established phenomenon.

210 glass substrates are one of the most common, well-established platforms for this purpose.

211 ffinity PP1 adaptor, able to out-compete the well-established PP1-inhibitor I2 in vitro.

212 al therapeutic effects of cortistatin in two well-established preclinical models of atherosclerosis,

213 icant prognostic information on top of other well-established prognostic variables (P>0.05 for all ou

214 evant prognostic information on top of other well-established prognostic variables.

215 Cardiac Troponins (T and I) are well established protein biomarkers associated with hear

216 We adapted a well-established protein-modeling framework, the Gaussia

217 ach, onion, salami, etc.) were compared with well-established protocols.

218 Despite their well-established qualities, conventional analyses such a

219 Using the well-established rat tail tendon collagen as a benchmark

220 DJ-1 is a well-established reactive oxygen species (ROS) scavenger

221 rmining region Y-related HMG box 2 (Sox2), a well established regulator of stem cell self-renewal and

222 Due to the well-established relationship between morphology and cel

223 Despite the well-established relevance of mechanical cues to cell be

224 Juxtaposing recent studies on well-established resistance pathways with that of emergi

225 LDL cholesterol is a well established risk factor for atherosclerotic cardiov

226 tory of cutaneous melanoma ('melanoma') is a well-established risk factor for melanoma.

227 Diabetes is a well-established risk factor for thromboembolism in pati

228 AF, MI, and CHF to a similar degree as other well-established risk factors.

229 Chronic social defeat stress (CSDS) is a well-established rodent model of depression that induces

230 This contrasts with the well established role of dopamine in the striatum, which

231 Despite a well-established role for the epidermal growth factor re

232 Besides its well-established role in generating COPI vesicles, we fi

233 In addition to its well-established role in maintaining skeletal health, vi

234 ripherin is performed independently from its well-established role in maintaining the high curvature

235 are highly effective antiviral drugs with a well-established role in primary prophylaxis and treatme

236 ng Abeta transport, also consistent with the well-established role of apoE4 in Abeta deposition in AD

237 Based on the well-established role of glutamatergic neurotransmission

238 Despite well-established roles as an inhibitor of cap-dependent

239 Given a well-established safety profile as an antibiotic, our re

240 The safety results were consistent with the well-established safety profile of ranibizumab.

241 g' approach, is wholly inconsistent with the well-established scientific evidence of the importance o

242 stimulated by a net flow, in addition to the well-established shear flow that arises from shearing be

243 lthough the oncogenic role of CUL4A has been well established, specific DCAFs involved in cancer deve

244 on relevant to mutation analysis compared to well-established substitution matrices.

245 ressed by the transcription factor Nkx2-1, a well-established suppressor of metastatic progression.

246 ost commonly performed major surgeries, with well-established symptomatic and prognostic benefits in

247 idths using methods of nonlinear optics is a well-established technology of modern laser science.

248 lecular biology and functional genomics is a well-established technology, in vivo applications of syn

249 n their reproduction are unclear even in the well-established teleost research model, the zebrafish.

250 It is well established that all seven serotypes of BoNTs (BoNT

251 It is well established that anthropogenic chlorine-containing

252 While it is well established that broad-scale patterns of abiotic an

253 It is well established that canonical eukaryotic pre-mRNA 3' p

254 It is well established that cardiorespiratory fitness (CRF) is

255 While it is well established that climbing fibre signals are importa

256 It is now well established that data from FFQs and other self-repo

257 nesis of this disease remains unknown, it is well established that endometriosis patients exhibit imm

258 Although it is now well established that gammadelta T cells can be rapidly

259 It is well established that glutamate and GABA signal through

260 Although it is well established that Influenza A virus infection is ini

261 Although it is well established that methylphenidate (MPH) enhances sus

262 It is well established that networks within multiple-demand co

263 Although it is well established that PD-1-PD-L1 blockade activates T ce

264 While it is well established that plants associating with arbuscular

265 It is now well established that Polmu is the one adapted to repair

266 It is well established that resource quantity and elemental st

267 It is well established that sensory afferents innervating musc

268 It is well established that somatic genomic changes can influe

269 Although it is well established that spoken word recognition engages th

270 Whilst it is well established that statistical and economic considera

271 Although it is now well established that the hippocampus supports memory en

272 Although it is well established that the number of menstrual cycles and

273 However, although it is well established that the receptive field surround is st

274 It is well established that these responses are also associate

275 It is well established that viral pathogens exploit PD to spre

276 It is well established that visual sensitivity to motion is co

277 It is well established that, apart from its distinct role in b

278 by patients approaching the end of life and well-established that patients and carers hold fears rel

279 It has been well-established that the known TMs can be classified by

280 lphaS) into oligomers and amyloid fibrils is well established, the aggregation propensity of other me

281 e of TH2 cells in type 2 immune responses is well established, the newly identified type 2 innate lym

282 mitochondria-mediated necrosis signaling is well established, the regulatory mechanisms of necroptos

283 ption limits based on toxicologic safety are well established, the threshold required to exert clinic

284 though the genetic link between GD and PD is well established, the underlying molecular mechanism(s)

285 mportance of the MyoA-light chain complex is well-established, the detailed mechanisms governing its

286 chromophores and its degradation by H2O2 is well-established, the second intermediate, 1,4,5,8-napht

287 afety of smoking cessation interventions are well established, their efficacy and safety in patients

288 Although hFPPS is a well-established therapeutic target for lytic bone disea

289 ods to establish where a TF binds to DNA are well established, these methods provide no information d

290 ecules by monocytes and macrophages has been well established; this is mediated primarily by pattern-

291 cytotoxins, and particularly ExoU, has been well established to determine a worse outcome both in re

292 Although the neuronal isoform Munc18a is well-established to bind tightly to both the closed conf

293 Baeyer-Villiger monooxygenases (BVMOs) is a well-established tool to address these challenges, but k

294 ies of such molecules can be uncovered using well-established tools, but the complex details of their

295 ranscriptional mechanisms in addition to its well-established transcriptional responses.

296 can be substantially altered not only by the well-established variables of temperature and pH but als

297 ntral nervous system myelination by GPR17 is well established, verification of activity of its putati

298 le of Zetaproteobacteria in mat formation is well established, we have a limited understanding of how

299 offspring leukocyte telomere length (LTL) is well established, with older fathers thought to pass on

300 language tasks and language networks is now well established, yet the specific cerebellar contributi