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1 ntrations of PARP inhibitor >1000-fold higher than the IC50 were required to ablate both ADP-ribosylation and XRCC1 chrom
2 oximately 4 and approximately 8 NO molecules, respectively, were required to abolish DNA binding.
3                                               All hospitals were required to be level 2A county general hospitals and ART
4                                         If multiple samples were required to be positive, specificity was increased to 10
5                                            Eligible studies were required to be relevant to the subject and provide suffi
6                                                    Patients were required to be taking an allowed antidepressant for at l
7 s because both anti-Mac-1 function-blocking mAb and heparin were required to block adhesion.
8                              Intriguingly, increased forces were required to convert hypermethylated dsDNA into an extend
9 thought that at least two taus in the trimeric DnaX complex were required to couple the leading and lagging strand polyme
10 ted in the same sample simultaneously; therefore, 2 samples were required to detect dual-strain infection.
11                 In several examples, large population sizes were required to detect GxEs.
12                             It was found that 750 particles were required to differentiate between all of the synthesized
13 ted Pen a 1 proteolysis, which simulates gastric digestion, were required to diminish secretory responses.
14 ing a delayed non-matching to sample task, in which monkeys were required to discriminate 4 categories of visual stimuli
15 cating that Myd88 and FcRgamma, presumably on myeloid APCs, were required to downregulate T cell help for the extrafollic
16 ions greater than those needed to inhibit HIV-1 replication were required to elicit significant alterations.
17                                                     B cells were required to expand IL-4-committed Tfh cells during the s
18                                                All subjects were required to fill in dry eye and smoking questionnaires,
19  known to be involved in posttranscriptional gene silencing were required to generate diRNAs.
20 ction of embryogenic calli and longer callus growth periods were required to generate these large libraries.
21  Participants referred for radiotherapy for bone metastases were required to have a pain score at the site(s) of treatmen
22 ts (from December 15, 2000, to September 1, 2001), patients were required to have advanced GIST that was not surgically c
23                                                    Patients were required to have at least 1% PD-L1 expression detected o
24                                                    Patients were required to have early-stage disease and gadolinium enha
25                                                Participants were required to have lived for at least the last 2 years in
26                                                   All cases were required to have nasal obstruction or discharge.
27                           The SPI-2 effectors SseF and SseG were required to induce binucleation.
28 hile one NB was sufficient to induce PPD1, more than 15 NBs were required to induce high levels of FT1 expression and a s
29 olymerization wherein various combinations of three stimuli were required to induce polymer chain growth.
30 upport PU.1 binding as a monomer, additional flanking bases were required to invoke sequential dimerization of the bound
31                              In Study 1, where participants were required to maintain and update working memory items, th
32                 In contrast, in Study 2, where participants were required to maintain working memory items without updati
33 ts with monochromatic radiation, data from only 50 crystals were required to obtain complete datasets.
34                             Considerable expertise and care were required to obtain the resulting datasets, which, despit
35                              Additional modifications at P3 were required to optimize the CV profile, and these combined
36                               Assessed individuals in CDDCs were required to participate in services such as counselling
37 oxidation, adaptations of existing chemical transformations were required to permit chemoselective reduction and oxidatio
38 her concentrations of L-ALD (40-60muM) than L-ZOL (3-10muM) were required to produce a comparative reduction in cell viab
39                                                CD103(+) DCs were required to promote anti-tumoral effects upon blockade o
40 hway inhibitor SB431542 together with ascorbic acid and EGF were required to promote hiPSCs-BAP differentiation at a leve
41                                        National governments were required to provide the WHO with formal validation of ex
42 een these alternatives we used a task in which participants were required to reach to either a single target or towards t
43 e) center-involved diabetic macular edema (DME) at baseline were required to receive ranibizumab for center-involved DME.
44                     Lower doses of the FLAP inhibitor MK886 were required to reduce LTB4 levels in exudates of female ver
45 h factor-beta activated kinase 1 (TAK1)-mediating signaling were required to spur inflammatory disease.
46             In this task, Asian elephants (Elephas maximus) were required to step onto a mat and pick up a stick attached
47                Elevated levels of oxidative phosphorylation were required to support both cytotoxicity and IFN-gamma prod
48                                               Interventions were required to support symptom management.
49                       A total of 370 nursing overtime hours were required to treat the injured patients on the day of the
50 ents were enrolled, successively randomly assigned patients were required to undergo annual radiographic (x-ray) analysis

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