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1 he C3 isoform uniquely inhibits the pathway, whilst 13 other isoforms upregulate signalling.
2 bute most strongly to bitterness perception, whilst 15-p-hydroxylphenylacetyllactucin-8-sulphate does
3 lly dominated by freshwater outburst events, whilst ~1500 year cycles in the late Holocene are more l
4 se individuals do not show excess liver fat, whilst 16% of lean individuals develop NAFLD.
5 conostoc mesenteroides subsp. cremoris (20%) whilst 25% CFS of Leu. mes. subsp. cremoris and Lc. lact
6 04% of teeth possessed type I canal systems, whilst 34.27% had two canals and 1.69% had three canals.
7                                              Whilst 86.57% of karyotypes show S-type organisation (an
8 quires further analysis of risk of exposure, whilst a cause for concern over deficiency might arise w
9 east altered fossil teeth of 253 +82/-70 ka, whilst a minimum age scenario yields an average age of 2
10                                              Whilst a number of binary DNA-complex X-ray crystal stru
11 -old immature parasitoids death in the host, whilst a small proportion of 5- to 6-day-old and the maj
12 rsi RI scales allometrically to mass(0.028), whilst a weak relationship exists in femora (mass(0.004)
13 d candidates for amino acid uptake from soil whilst AATs highly expressed in senescing leaves and ste
14 entration' for epicatechin and caffeic acid, whilst addition of caffeoylquinic acids resulted in dose
15                                              Whilst administration of long-term release prednisolone
16 o lead healthy, active and independent lives whilst ageing.
17                                              Whilst allogeneic fibroblasts injected directly into the
18    Tyrosol was converted into hydroxytyrosol whilst alpha-methyl-L-tyrosine did not inhibit the biotr
19 uent use of capture and reporter antibodies, whilst also avoiding the need for any post-amplification
20  virtually any solid surface as a reflector, whilst also being highly portable.
21 hese methods than DOC derived from Sphagnum, whilst also being less susceptible to microbial minerali
22 e C. parvum oocysts with over 90% certainty, whilst also detecting damaged and/or excysted oocysts.
23 production by up to 58% in certain habitats, whilst also driving a deviation from natural phase propo
24 reasing in amount as the culture progresses, whilst also facilitating egress of increasingly differen
25 shwater biodiversity in urbanized landscapes whilst also facilitating key ecosystem services includin
26 ework to explain how EspG disrupts recycling whilst also reporting the first known simultaneous targe
27 s to allow filament compaction and bundling, whilst also retaining extensibility to ensure flexibilit
28 ation in the early stages of drug discovery, whilst also widening the range of communities participat
29 teria (76 +/- 2%) were metabolically active, whilst AMR bacteria to carbenicillin, kanamycin and both
30 flesh increases the disease burden by >1000% whilst an education campaign to freeze anchovy before co
31 er approaching individuals explored earlier, whilst animals with long initial approach latencies show
32 of 5 mg.mL(-1) all glycopeptide is dimerized whilst at 19 microg.mL(-1) (a clinical target trough ser
33 euronal spike rate autocorrelation structure whilst at rest.
34 oth significantly correlated with HIF-1beta, whilst AT2R also correlated with HIF-1alpha (r = 0.512,
35 .5) reported the biggest increase among men; whilst Australia (AAPC = 13.4, 95% C.I. = 4.1, 11.5) sho
36 ntly spread C. neoformans in the environment whilst avoiding systemic disease.
37 having 'harsh' and 'progressive' bitterness, whilst beers that had evidently been conventionally hopp
38 nd relatives to deliver mealtime assistance, whilst being available at mealtimes to support patients
39 pase-8 activity and, consequently, apoptosis whilst being itself cleaved in a caspase-8-dependent man
40 lar functions of a vast range of substrates, whilst being minimally invasive to the cells or tissues
41                                              Whilst brewing sorghums were of lower protein content, p
42 dinating residues W293(6.48) and N150(3.35), whilst buprenorphine and diprenorphine did not.
43  levels and trafficking to the cell surface, whilst C436R was not trafficked at all.
44 festol are diterpenes present in coffee, but whilst cafestol is found in both Coffea canephora and Co
45  the proliferation of cells by 52.1% at 48h, whilst catechin, epicatechin, quercetin and gallic acid
46 54mg/kg) and trans-ferulic acid (1.85mg/kg), whilst (+)-catechin was the major flavanol.
47                                              Whilst causes of hepatic artery thrombosis (HAT) after l
48 nel in that it selectively modulates Cav3.2, whilst Cav3.1 and Cav3.3 are unaffected.
49                                              Whilst CFTR's function as an ion channel has been well d
50 ntain the ability to colonize multiple hosts whilst competing with specialists in the same niche.
51  precision of audiovisual timing estimation, whilst concomitantly decreasing the prior expectation th
52 P, limiting its interactions with substrates whilst conserving ATP.
53 e to tolerate loadings as low as 0.002 mol % whilst conserving high activity (TOF=12 500 h(-1) ).
54                                              Whilst currently not as sensitive as amplification-based
55 on in glutamate and glycine agonist potency, whilst D731N was non-responsive.
56 6 lack heparan sulphate and focal adhesions, whilst depletion of ADAMTS6 induces a prominent glycocal
57 tent destruction of the extracellular matrix whilst displaying distinct efficiencies for the cleavage
58 sing techniques to reduce acquisition times, whilst distributing the optical illumination over the fu
59                                              Whilst DNA analysis has helped to combat this type of fr
60 to drought in the core of the species range, whilst dry range edge populations showed particularly hi
61                                              Whilst elements of the inner core are conserved, numerou
62                                              Whilst elevated plasma n-3 polyunsaturated FA (PUFA) was
63 es CRP-dependent Class II promoter activity, whilst elevating CRP steady state levels, thus indirectl
64 o is restricted to 10:1 w/w to maximise dose whilst ensuring that the dry-coated payload does not sig
65                                              Whilst enzyme-catalyzed chlorination is accomplished wit
66  locating relevant courses and finding gaps, whilst establishing a Master of Management programme.
67 32-0.79, P = 0.003), but not other outcomes, whilst exclusive breastfeeding for >4 months protected a
68     Broadly neutralizing antibodies (bNAbs), whilst exhibiting neutralization breadth and potency, ar
69                                              Whilst exposure to 0.5 mg L(-1) AgNPs had no significant
70 rgy) and family history of allergic disease, whilst exposure to pet dogs was protective for all pheno
71 urface engineering is an expanding field and whilst extensive research has been performed decorating
72 n the other hand, pairs who exchanged forces whilst facing one another consistently under-reproduced
73 ratures above 17.5 degrees C for G. pallida, whilst females per plant were optimal between 17.5 and 2
74  by conifer litter or weedy angiosperms, and whilst fern understories supported the most rapid fire s
75 agnetisation regions with spatial gradients, whilst field-like and spin-like torques are reproduced i
76 re capable of strand displacement synthesis, whilst filling DNA gaps or partially annealed DNA ends,
77 ociated with worse job performance outcomes, whilst fixed night shifts appeared to enable resynchroni
78 to dopamine neurons expressing TH and Pitx3, whilst FolR1 negative cells generate non-dopaminergic ne
79 icant initial temperature drop was observed, whilst for both agents a significant temperature drop wa
80 able to the loss of cold-associated species, whilst for butterflies, warm-associated species have ten
81 nd presence of magnetic field, respectively, whilst for Fe@C-Fc-2 was 0.4 and 0.07mugdL(-1) in the ab
82 sformant AS5 failed to colonize the compost, whilst for those that did colonize the compost, 60% gave
83  risk of predation by reducing exposure time whilst foraging and allowing more time to be vigilant; (
84  Some species vocalize at key life stages or whilst foraging, and disruption to the acoustic habitat
85 ighting the most significant recent advances whilst giving an appropriate background for the general
86 acterial lysis was observed at 37 degrees C, whilst growth was maintained at the uninfected skin temp
87                                              Whilst >450 skeletal dysplasias have been reported, 30%
88 ively protects NCTC cells against radiation, whilst HepG2 neoplastic cells are sensitized.
89 Visual impairment will occur if uncorrected, whilst high myopia causes sight-threatening complication
90 ients with a CI defect of Mendelian origins, whilst highlighting the necessity of complete mitochondr
91                                              Whilst historically regarded as being of minor importanc
92                                     However, whilst human beta2m (hbeta2m) forms amyloid-like fibrils
93 , including those with multi-line sequences, whilst identifying invalid files.
94 ase impairs the inhibition of responses, and whilst impulsivity is mild for some patients, severe imp
95 file varied depending on geographical origin whilst in chocolates only carbohydrates and fat content
96 vity correlates positively with their ageing whilst in circulation.
97 ped guard cells could be attributed to size, whilst in elliptical-shaped guard cells features other t
98  variables in determining SAF values in men, whilst in female participants, SR was also highly correl
99 e suspension can be monitored quantitatively whilst in flow using x-ray phase contrast imaging.
100 -PCR analysis in distinct Arachis genotypes, whilst in situ hybridization revealed transcripts in dif
101 ions were observed only in eastern Amazonia, whilst in western Amazonia there was an unusual wetting.
102 croscopic level in large protein structures, whilst incorporating anharmonicity in the inter-residue
103 ed dopaminergic neurotransmission and mania, whilst increased striatal dopamine transporter (DAT) lev
104                             It is known that whilst inside a host cell the tachyzoite maintains its s
105                                              Whilst interaction with PDK1 and the mTORC2 complex comp
106 lop fear/aggression related issues early on, whilst issues related to training could develop at almos
107 001) in 18:3 n-3 (115 vs. 180 mg/100 g) and, whilst it contained more (P<0.001) docosahexaenoic acid
108 rformance of donor-acceptor heterojunctions, whilst it has remained challenging to investigate the de
109                                              Whilst it is well established that statistical and econo
110  as a simple prognostic biomarker in AF and, whilst its addition to current scores statistically impr
111 tes it within the endoplasmic reticulum (ER) whilst its transactivation domains [TADs, including acid
112 agments lacking chemokine-inducing capacity, whilst keeping synergy with cytokine-induced chemokines
113 entric through manipulating the task demands whilst keeping the physical stimulus constant by measuri
114 d these risk estimates to be underestimated, whilst lack of data on lipids may have resulted in resid
115 pounds that potently inhibit LTB4 generation whilst leaving PGP degradation unperturbed.
116 l and tibiotarsal width scale with isometry, whilst length scales with negative allometry, and close
117 ws strong positive allometry with body mass, whilst length shows strong negative allometry.
118                                     However, whilst limb loss is unlikely to be adaptive, females wit
119 activity (508-541 mug trolox equivalents/g), whilst LSF extracts exhibited potential antihypertensive
120 tation did not improve antioxidant activity, whilst LT pasta showed unconventional taste and odor.
121                                              Whilst lying in the supine posture, central venous press
122 ical diseases (NTDs) encourages integration, whilst maintaining existing structured NTD investments,
123    To overcome mitochondrial DNA deficiency, whilst maintaining genetic identity, we supplemented pig
124 iophysical properties and serum persistence, whilst maintaining high affinity and potency.
125 s that could enable shorter detection times, whilst maintaining high analytical performance.
126  able to operate at bandwidths up to 1.5 kHz whilst maintaining internal gain as large as 10(6) .
127 olubilities relative to our prior analogues, whilst maintaining strong potencies as AgrC receptor inh
128 continued evolution of bacterial resistance, whilst maintaining the activity and stability of such pr
129  them to be soluble or dispersed in solution whilst maintaining their structure and function, necessi
130                                              Whilst mammalian IFN-induced miRNA are known to inhibit
131                                              Whilst many children with asthma or rhinitis are sensiti
132                                              Whilst many metal-organic frameworks possess the chemica
133                        Our results show that whilst many mRNAs are changed by long-term genetic pertu
134                                              Whilst many of the resulting founder (F0) mice developed
135                                              Whilst many of these phenotypes are 'direct' effects of
136                                              Whilst many show promise in vitro, the clinical potentia
137 s thus spontaneous and minimises aggregation whilst maximising correct folding.
138 arkedly improved by model-based integration, whilst maximum predictive capability was obtained with e
139                                              Whilst mechanisms underpinning impaired uteroplacental v
140                                              Whilst methodological and reporting limitations in the i
141 is that use of an objective primary outcome, whilst minimising detection bias, may have underestimate
142 nosed children with developmental disorders, whilst minimising incidental findings.
143 h the aim of resolving IVD 3D microstructure whilst minimising sample preparation artefacts.
144  adjuncts must address practical constraints whilst minimizing risks of adverse effects.
145      No single case of recurrent RD was seen whilst mixed oil remained in situ.
146                                              Whilst MLT contained significantly increased polyphenols
147 otes underwent morning light administration, whilst monitoring sleep-wake patterns and the urinary 6-
148 s on flocks of wild great tits and blue tits whilst monitoring their social dynamics.
149 ue to the exposure of the hydrophilic plane, whilst more robust tablets were produced.
150                                              Whilst most bacterial species contain a single ClpP prot
151                                              Whilst most focus has been on targeting binding-site cys
152                                              Whilst most phosphosites were unaffected, we strikingly
153                                              Whilst much is known on the signaling components mediati
154                                              Whilst Nature almost by default (transiently) organises
155  associated with clinical patients' outcome, whilst no association was detectable at the gene express
156 containing high-moment zinc-doped particles, whilst no signal was observed in cells containing the hi
157 mediary molecule in the information network, whilst noncoding RNAs perform additional diverse functio
158 tive of independent spatial representations, whilst nonetheless sharing idiosyncratic variations in s
159                                              Whilst not being quantitatively similar across genders,
160                                              Whilst not eschewing folk psychology, it is useful to re
161                                              Whilst numerous studies have shown that individuals ofte
162                                              Whilst O. ophiodiicola has been isolated from captive sn
163 f changes in extracellular matrix stiffness, whilst observing the ability of PSCs to durotactically r
164 ed the aroma of the final pineapple vinegar, whilst off-flavors were significantly reduced relative t
165 hat folivores species have the weakest jaws, whilst omnivores have the strongest mandibles within the
166  which can lead to immune system activation, whilst, on the other hand, E. coli may contribute to the
167 by research-grade microscopy (92.6%; 25/27), whilst one of three infectious individuals in the lowest
168 ng structural subunits and assembly factors, whilst only 3 of the 10 patients with mutations affectin
169 rated partial cell death reversal in SKOV-3, whilst only caspase 9 was effective in PC-3.
170 w-risk and high-risk patients appropriately, whilst ORBIT and ATRIA categorised most major bleeds int
171                                              Whilst [Os(N^N)3 ](2+) complexes are supposed to be phot
172 explains why some older adults are resilient whilst others are not.
173                                        Thus, whilst our data support the hypothesis that access to el
174 nt responses with NF-kappaB and Smad2/3 TFAR whilst our Notch reporter was repressed over the 40 days
175                 Our simulations suggest that whilst our study sites will experience some climatically
176                                 For example, whilst oxidized sp(3) carbon atoms and vacancies in a gr
177                                 Furthermore, whilst Pa ESP can rescue the chromatid nondisjunction ph
178 atitis is the most common pancreatic disease whilst pancreatic cancer is the most lethal.
179                                              Whilst pathogen serology is typically performed by centr
180                                              Whilst patients can achieve a 6% improvement in overall
181 ging through smoke, through a tinted screen, whilst performing compressive sampling and recovering hi
182                                 Furthermore, whilst pericentral cells tend to show higher lipid level
183 or effective activation of the ARC channels, whilst phosphorylation of the same residue actually inhi
184  the buffering capacity of seawater for CO2, whilst photosynthetic carbon fixation has the opposite e
185  phenotype, so-called phenotypic modulation, whilst plaque macrophages are thought to derive from blo
186 ater pCO2 in two genotypes of Porites lutea, whilst Porites murrayensis is unaffected.
187  employed to estimate radiation profile, and whilst powerful, these are computationally expensive, li
188                                              Whilst powerful, this model does not explain several cli
189 ly increased stability in detergent micelles whilst preferentially occupying a single conformation.
190                                              Whilst preliminary, these results offer new perspectives
191 ng functional brain imaging and eye-tracking whilst presenting an apparent motion illusion.
192  that of most other natural cellular solids, whilst preserving an excellent mechanical strength.
193                     Our results suggest that whilst programmed reductions in IRS-1 are associated wit
194  therefore focus on retarding VSMC apoptosis whilst promoting VSMC proliferation.
195  impacts the functional properties of genes, whilst providing ohnologues available solely for lineage
196 ty without conventional resource limitations whilst providing robust security.
197 el; which permits high reflection capability whilst providing vivid, polarization switchable, wide co
198 l and phase locking to SWRs in rTg4510 mice, whilst putative pyramidal neurons showed increased tempo
199 and kidneys (cisplatin) in vivo and ex vivo, whilst qPCR, Taqman low-density array and immunoblot ana
200 ve impact on employee fatigue and alertness, whilst quick returns between shifts appeared to increase
201 characteristic of L. purpureus were detected whilst R. aurorubens generated only the control band.
202 erence vanishes for quantum-classical states whilst reaching a maximum for pure entangled states with
203 ation and aerobic capacity are thus limited, whilst reactive oxygen species (ROS) production increase
204                                              Whilst recent genetic fate-mapping studies using lineage
205 ystem is necessary to increase food security whilst reducing emissions.
206 vour and nutritional content of potted herbs whilst reducing the deleterious impacts of dense plantin
207                                              Whilst remodelling changes in AR are limited, CRS phenot
208 y upregulate NF-kappaB and Smad2/3 activity, whilst repressing Notch signalling.
209                                         Even whilst research continues to improve the underlying mode
210          The model predictions indicate that whilst resilience to this generalist pathogen in the hos
211                                              Whilst resonant transmission is well understood and can
212 xuality and explore the roles they may adopt whilst responding and managing sexual needs and expressi
213  increased fasting fat oxidation (P < 0.01), whilst resting energy expenditure increased after HA and
214                                              Whilst resting, the inter-beat (R-R) time series of twen
215 the composition of each localised SiGe area, whilst retaining a uniform composition in that area.
216                                              Whilst sampling-related gene expression changes are evid
217 ayers of powder particles atop of each other whilst selectively melting the corresponding part cross-
218  tested pairs who knowingly exchanged forces whilst separated by a curtain.
219                                              Whilst sequences derived specifically from each of the c
220 n is to inhibit mTOR under stress conditions whilst several in vitro studies indicate that its expres
221 nections terminate between specific modules, whilst short range connections via highly curved associa
222 let activation, aggregation, and thrombosis, whilst simultaneously activating enzymatic processes tha
223 macological analysis of CNS active compounds whilst simultaneously determining their effect on synapt
224 erent platelets, reduced platelet spreading, whilst simultaneously promoting actin nodule formation.
225 ra-operatively via implanted DBS electrodes, whilst simultaneously recording muscle activity of the a
226 stained in the face of changing epidemiology whilst simultaneously tackling significant pockets of su
227 to angiotensin II (Ang II) and dietary NaCl, whilst SM-alpha2 overexpression lowers basal BP and decr
228                                              Whilst some treatments work by increasing insulin secret
229                                              Whilst SS-hAFSCs are routinely expanded in mesenchymal-t
230 e double diamond phase ([Formula: see text]) whilst still allowing for modest increases in lattice pa
231 umber of sequences displayed on the website, whilst still providing access to many important model or
232  and when added in food products, are stable whilst stored under the appropriate conditions.
233 line biases STDP toward synaptic depression, whilst subsequent application of dopamine converts this
234                                              Whilst such structures have been documented in many ocea
235  compartments, preserving cell architecture, whilst supporting signalling and selective transport tha
236                             We conclude that whilst symmetrical motion per se does not contribute to
237 between endothelial cells driving branching, whilst synchronization drives vessel expansion.
238 ifically inhibited DisA but not YybT (a PDE) whilst TA was more promiscuous and inhibited both DisA a
239                                              Whilst TasP can greatly reduce HCV prevalence, incidence
240  h(-1) (0.1 mol % loading, 298 K, [LA]=1 m), whilst that with a "planar" conformation is much slower,
241 2 are essential for cranial axon patterning, whilst the 2-O-sulfotransferase HS2ST (also known as HS2
242  DC3000 lacking hopQ1-1 [PtoDC3000(DeltahQ)] whilst the activity profile of the beta1 subunit changes
243                                              Whilst the biodistribution of LNCs of different size has
244     The sourdough process fully degraded IP6 whilst the CBP and conventional processes reduced it by
245  ratio (CNR) of iodine was highest at 80 kV, whilst the CNR for gold was highest at 140 kV.
246 epertoire of inhibitory effects on swimming, whilst the D4 receptor antagonist, L745,870, had the opp
247                                              Whilst the energy difference between polymorphs is usual
248                                              Whilst the exact spectrum and functions of these genes a
249                                              Whilst the focus has been on optimal approaches to achie
250                                              Whilst the former requires an appreciation of the common
251                                              Whilst the fossil record of polychaete worms extends to
252                                              Whilst the generalist induced very similar perturbations
253                                              Whilst the induction of proteostasis-related genes was d
254                                 We find that whilst the intensity of competition (percentage of bryoz
255 ve on the 1% of Antarctica that is ice free, whilst the largest animals that have ever lived on Earth
256 n and stabilisation (Gly, Pro, Hyp and Hyl), whilst the Lys content was greater for the WP group, ind
257 m membrane regulating CRAC channel activity, whilst the minor pool of plasma membrane STIM1 regulates
258 ce and the atomic carbon source are similar, whilst the nature of the carbon aggregates is different
259                                              Whilst the primary molecular mechanism of some DCM-assoc
260                                              Whilst the profiling of the transcriptome and proteome e
261 t led to an increase in cell wall thickness, whilst the quantity and sugar composition of the cell wa
262 y by betaG, suggesting dynamic interactions; whilst the reduced line widths/intensities observed were
263 lease over three-fold (from 3days to >9days) whilst the release of all-trans retinoic from the silico
264 s will have reduced germination performance, whilst the remainder will have an efficiency gain, by th
265 he amino acid aspartate is precisely adapted whilst the response to serine is not, in spite of the sa
266                                              Whilst the scientific community was still puzzling about
267                                              Whilst the sequence of events during this period is reas
268  negative correlation with fungal occurrence whilst the total sugars had a positive correlation.
269 lactose system than WPH-lactose counterpart; whilst, the DPPH scavenging activities of WPH-sugar conj
270                                              Whilst, the particle shapes of the two crystal forms wer
271                                              Whilst their ability to predict clinical outcomes has be
272 tury when bottom trawling became widespread, whilst their environment became increasingly impacted by
273                                              Whilst there have been many theoretical models predictin
274                                              Whilst there is good evidence for cystatin C being a mar
275                                              Whilst there is increasing evidence that the gut contrib
276  acids and synthetic agonists was maintained whilst there was marked loss of agonist potency for sign
277                                              Whilst there was overlap with HRSV, there was unique com
278                                         Thus whilst these deposits provide invaluable information on
279                                              Whilst these have led to significant discoveries, prelim
280    Using 3D motion-capture we recorded women whilst they danced to a basic rhythm.
281 CD patients with 16 matched healthy controls whilst they performed a sequential information gathering
282 33-131 genes differentially expressed (DE)], whilst those between control and spring plants (adaptati
283 ons appear to be directly involved with DNA, whilst those from DrDps2 are indirectly associated with
284                                              Whilst those in more disadvantaged areas would pay more
285 tio 0.74 CI95% 0.58-0.94) compared to Whites whilst those with greater educational levels were more l
286  MNs was retained for longer in the skin and whilst topical hydration of the skin with vehicle or ste
287 rongly absorbs unwanted off-axis light rays, whilst transmitting the desired on-axis rays, to achieve
288  of phenolic compounds, including stilbenes, whilst treatments with kresoxim-methyl, fluquinconazole,
289 on-competitive inhibition (decreased V max), whilst uncompetitive inhibition (decreased V max and K m
290 d therefore a blue, rather than green colour whilst undergoing fluorescence.
291 f the tea plant which are steamed and dried, whilst undergoing minimal oxidation.
292                                              Whilst understanding nutrient constraints on productivit
293 re responsible for 52% of total bait removal whilst vertebrates and non-ant invertebrates removed the
294 bjects performed an attention-demanding task whilst viewing task-irrelevant objects.
295                                              Whilst washing with the control tap water (28mug/L As) r
296                                              Whilst we did not examine any protective role to re-chal
297                                              Whilst we found no significant differences in subcortica
298       The concept of self-management support whilst well characterised in the context of chronic illn
299                                        Thus, whilst WGS provided some increased resolution over varia
300 rt axis) embedded within the polymer matrix, whilst X-ray Photoelectron Spectroscopy (XPS) confirmed

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