ライフサイエンスコーパス: whole

1 ctionality of HSCs and the blood system as a whole.

2 uture growth prospects of the community as a whole.

3 le into a helical strand that runs along the whole approximately 1 mum length of a thin filament.

4 ng microfluidic systems for nucleic acid and whole bacteria immunoassay tests, their practical applic

5 stry to fluorescently label the mature PG in whole bacterial cells of Bacillus subtilis.

6 The lower correlations obtained with the whole basin apparently reflected variable losses of MeHg

7 Three-dimensional (3D) optical imaging of whole biological organs with microscopic resolution has

8 cooking quality and phenolic composition of whole black and red rice grains stored during six months

9 0.57), urine (6.36; 95% CI, 2.48-16.32), and whole blood (11.88; 95% CI, 4.12-34.20).

10 ent of enzymatic amperometric biosensors for whole blood analysis, to enhance the enzymes stability a

11 idate 6 shows good potency in an IDO-1 human whole blood assay and also shows a very favorable ADME p

12 ved the ability of yolkin to stimulate human whole blood cells to release anti-inflammatory cytokines

13 325-4 attenuated bacterial survival in human whole blood ex vivo, which was associated with increased

14 To explore this, serum, plasma, and whole blood from 61 adults in Oslo, Norway were collecte

15 The measured values of whole blood from the micro-channel (4.17cP) and the vacu

16 We used microarray data on whole blood from two independent case-control studies of

17 ated positively with mycobacterial growth in whole blood from UK/Asian adults and, to a lesser extent

18 al epigenome-wide methylation analyses using whole blood highlighted 36 differentially methylated sit

19 s that are highly heritable and expressed in whole blood in 1748 unrelated individuals of European an

20 Here, whole blood of healthy seropositive individuals (n = 75)

21 We assessed global RNA expression levels in whole blood samples from 150 participants, representing

22 a human validation by collecting fingerprick whole blood samples from 20 participants to assess iron

23 l CD63 expression was transiently reduced in whole blood samples from both omalizumab- and placebo-tr

24 nce standard, a test for NK cell activity in whole blood samples identified patients with CRC with 87

25 In vitro exposure of human whole blood to PhNHOH and NOB demonstrated that only sul

26 cyte viability and erythrocyte morphology in whole blood under ambient storage.

27 solation devices by increasing the processed whole blood volume.

28 bronchoalveolar lavage (BAL), and peripheral whole blood was collected into PAXgene tubes for all sub

29 Activity was determined in whole blood, plasma, and urine.

30 ts had expression quantitative trait loci in whole blood.

31 or molecular detection of bacterial DNA from whole blood.

32 a triglycerides, or clock gene expression in whole blood.

33 nditions such as in platelet-rich plasma and whole blood.

34 ractive alphavbeta3 receptors that influence whole-blood 5-HT levels and may influence the risk for a

35 ide inhibitor of C5 cleavage, using in vitro whole-blood assays and an in vivo baboon model of Escher

36 We developed and validated a multivariate whole-blood mRNA-based predictor of melatonin phase whic

37 in a defined leukocyte subset from patients' whole-blood specimens.

38 ased approach in combination with individual whole-blood time-activity curves in the other 8 subjects

39 effective doses to individual organs and the whole body were calculated using OLINDA/EXM 1.2 for the

40 in neuroblastoma cells significantly reduced whole body, lung, kidney and liver metastases in an expe

41 icotine and the absorbed radiation dose from whole-body (11)C-nicotine PET imaging of 11 healthy (5 m

42 All patients underwent a preoperative whole-body (18)F-FDG PET/CT scan at 1 h (standard examin

43 Whole-body (18)F-FDG PET/MRI scans were obtained for 12

44 Whole-body (18)F-fluodeoxyglucose positron emission tomo

45 JAK2L mice had hepatic steatosis and severe whole-body and hepatic insulin resistance.

46 resence of metallic implants, to be used for whole-body attenuation correction in integrated PET/MR s

47 reover, Rosa26-mT/sr39tk mice are useful for whole-body characterization of transgenic Cre mice and t

48 To assess inter-observer agreement of whole-body computed tomography (WBCT) in staging and res

49 Of 1461 patients who underwent a whole-body CT examination, 39% (574 of 1461) had signs o

50 Purpose To determine the usefulness of whole-body diffusion-weighted imaging (DWI) to assess th

51 PET imaging was used to evaluate the whole-body distribution of (89)Zr-deferoxamine (Df)-pemb

52 nction and subsequent defects in maintaining whole-body energy balance might be early events that con

53 fat (LCHF) diet markedly increases rates of whole-body fat oxidation during exercise in race walkers

54 Under such conditions, fructose lowers whole-body glycogen synthesis and impairs subsequent exe

55 or in the parametric Ki images compared with whole-body images for both (68)Ga-DOTATOC and (68)Ga DOT

56 (18)F-MFBG intravenously followed by serial whole-body imaging at 0.5-1, 1-2, and 3-4 after injectio

57 These results show the potential use of whole-body imaging for receptor status assessment, parti

58 uglycemic clamps were performed to determine whole-body insulin sensitivity.

59 -1)) that was much higher than the estimated whole-body km (0.03 d(-1)).

60 ue to the central role of skeletal muscle in whole-body metabolism, we aimed at studying muscle lipid

61 d that stroke rates, including tail beat and whole-body movements during feeding, were faster (approx

62 The recent introduction of simultaneous whole-body PET/MR scanners has enabled new research taki

63 dvanced metastatic PCa via sequential planar whole-body SPECT imaging at 1, 3, 5, and 21 h after inje

64 aracterize the modification of shivering and whole-body thermal sensation during cold stress followin

65 aphic activity (EMG), metabolic rate (M) and whole-body thermal sensation on a visual analogue scale

66 significantly reduced the annualised rate of whole brain atrophy in patients with secondary progressi

67 d that information capacity measured through whole brain models is a theory-driven measure of process

68 Whole brain radiotherapy (WBRT) is the standard of care

69 The whole brain was segmented according to white and gray ma

70 Whole brain white matter integrity of HD-monkeys was exa

71 d at single-neuron resolution throughout the whole brain.

72 Mapping whole-brain activity during behavior represents one of t

73 ed between 47 regions of interests, of which whole-brain and region-specific means were compared by u

74 ribed [12]; however, combining an atlas with whole-brain calcium imaging has yet to be performed in v

75 alyses revealed that amisulpride changed the whole-brain connectivity patterns of individual OFC subr

76 volumes of cortical neuropil, plausibly even whole-brain datasets.

77 e anterior fundus (AF) face patch, combining whole-brain fMRI with longitudinal single-unit recording

78 Using whole-brain functional magnetic resonance imaging in mac

79 METHOD: A PubMed search was conducted for whole-brain functional neuroimaging articles published t

80 ibed topics that enable flexible decoding of whole-brain images.

81 nous analgesia, we used brainstem optimized, whole-brain imaging to record responses to concurrent th

82 individuals with MDD had significantly lower whole-brain intrinsic functional connectivity in the med

83 multaneous deconvolution of O(105) traces of whole-brain larval zebrafish imaging data on a laptop.

84 cluded a direct test of this hypothesis in a whole-brain setting.

85 We applied dynamic-pattern analysis to whole-brain slow (< 5 Hz) cortical dynamics recorded by

86 Using whole-brain voxel-based morphometry analysis, we found t

87 effects on temporal lobe cortical thickness (whole-brain voxelwise analysis: familywise error correct

88 nces in pseudoreference VT or SUV, excepting whole-brain VT, which was higher in cLBP patients than c

89 the partial-breast group, compared with the whole-breast radiotherapy group).

90 p<0.0001 for partial-breast]) compared with whole-breast radiotherapy.

91 on migration is a synergetic process and the whole carbonate structure is actively involved.

92 Whole cell biosensors have been seldom used in the pharm

93 tional approach for de novo sequencing using whole cell E. coli lysate.

94 C-MS/MS analysis (SCX-RPLC) of S. cerevisiae whole cell lysate was used to generate a retention datas

95 ditional viable count techniques; the use of whole cell microbial biosensors potentially provides an

96 rophysiological studies were conducted using whole cell patch-clamp to explore biophysical properties

97 Whole cell recordings revealed that the isoflurane-activ

98 Since whole cell responses most often arise from the coordinat

99 Here, we have characterized nuclear and whole cell transcriptomes in mouse single neurons and pr

100 irmed a high concordance between nuclear and whole cell transcriptomes in the expression of cell type

101 show that BKCa-CaV stoichiometry can affect whole-cell behavior substantially.

102 We found that UBP684 potentiated the whole-cell currents observed under perforated-patch cond

103 Whole-cell inclusion immunofluorescence serum antibody t

104 lting peptide (TAT-C1aB) suppressed enhanced whole-cell K(+) currents produced by a mutated form of K

105 his is associated with a gradual increase in whole-cell membrane capacitance.

106 r BKCa description into previously published whole-cell models, and perform simulations of electrical

107 Whole-cell mount has the simplest sample preparation but

108 Killed whole-cell oral cholera vaccines (kOCVs) are becoming a

109 -G2 exhibited similar channel properties in whole-cell patch clamp experiments.

110 ssion at the endbulb of Held was assessed by whole-cell patch clamp recordings from auditory neurons

111 We used in vitro whole-cell patch-clamp recordings with laser-scanning ph

112 t silencing of STN neurons as measured using whole-cell recording ex vivo.

113 Whole-cell recordings in L2/3 of awake mice revealed tha

114 smission in the rat PL were determined using whole-cell recordings in layer V pyramidal neurons.

115 the sarcoplasmic reticulum structure at the whole-cell scale, by reducing its full 3-D structure to

116 ased on the use of Micrococcus lysodeikticus whole cells adsorbed on graphene oxide (GO)-coated Surfa

117 nt to produce contigs, each representing one whole chromosome.

118 ion or degradation of ATR in mitosis induces whole-chromosome missegregation.

119 on on intrinsic particle properties from the whole class of interacting magnetic fine particle system

120 In this study, whole crickets (Gryllodes sigillatus) were hydrolyzed wi

121 The Principal Component Analysis of the whole dataset pointed out that the TF system at reduced

122 o track the metabolic changes throughout the whole development of astringent ('Giombo') and non-astri

123 Parts of the whole ecosystem such as natural wild plants, soil dwelli

124 will impact the structure and functioning of whole ecosystems.

125 Using the MIC method, 350mg of whole egg powder and its fractions were efficiently dige

126 m were randomized at age 4 months to receive whole-egg powder or placebo (rice powder) until 8 months

127 main protein in fission yeast, we visualized whole eisosomes and, after photobleaching, localized rec

128 se a novel numerical approach to compute the whole-embryo dynamics of the actomyosin-rich apical epit

129 accurately identifies causative variants in whole exome and whole genome sequencing datasets and pro

130 Recently whole exome sequencing (WES) has become primary strategy

131 A trio-based whole exome sequencing analysis in the first family dete

132 Moreover, whole exome sequencing and targeted sequencing of the ma

133 Whole exome sequencing identified a single mutation in S

134 reliable and rapid ethnicity annotation from whole exome sequencing individual's data, validated it o

135 gle-nucleotide variants (SNVs) by conducting whole exome sequencing of 18 trios consisting of Japanes

136 We performed whole exome sequencing on six out of nine members in a t

137 nown, despite many of them being screened by whole exome sequencing.

138 An integrative analysis of whole-exome and RNA-sequencing data was employed to exte

139 Optimal use of whole-exome sequencing (WES) in the pediatric setting re

140 f detecting causative recessive mutations by whole-exome sequencing (WES), we analyzed individuals wi

141 characteristics of CM using next-generation whole-exome sequencing (WES).

142 Using whole-exome sequencing and transcriptional profiling, we

143 Whole-exome sequencing in 997 subjects failed to identif

144 By using whole-exome sequencing in a further Palestinian-Jordania

145 ctive cohort study, we performed multiregion whole-exome sequencing on 100 early-stage NSCLC tumors t

146 We performed whole-exome sequencing on individuals with histologicall

147 Whole-exome sequencing revealed homozygous missense muta

148 lower average false genotype rate than using whole-exome sequencing to assess more than 300 genes in

149 We used whole-exome sequencing to detect the presence of CHIP in

150 Whole-exome sequencing was performed to identify gene va

151 al. performed next-generation sequencing and whole-exome sequencing, identifying new driver genes whi

152 By whole-exome sequencing, we identified a heterozygous tru

153 By using whole-exome sequencing, we identified a novel missense m

154 tion based on the off-target reads from deep whole-exome sequencing.

155 Radiogenomic multiparametric MR imaging and whole-exome spatial characterization in six patients wit

156 epsy panels (28 of 96 [29.2%]; P < .001) and whole exomes (5 of 18 [27.8%]; P = .02) than for chromos

157 tuning for partial face stimuli compared to whole face stimuli.

158 nd females in roughly equal numbers, perhaps whole families, whereas the later Bronze Age migration a

159 ationalizing the transport properties of the whole family of molecular semiconductors and is also use

160 ssociated with a higher risk of T2D, whereas whole-fat yogurt intake was associated with a lower risk

161 rst one (possibly associated to hot spots or whole Fermi sheets) has a strong mass enhancement at the

162 ally use singular features of the data (e.g. whole fluorescence).

163 ation of a sustainable method to exploit the whole fruit, both edible and non-edible parts, as a sour

164 t, and only a 400-kb deletion, including the whole-gene cluster, was eventually able to merge the nei

165 d clustering algorithm, our approach turns a whole genome assembly problem into a set of independent

166 that also included the random effects of the whole genome background.

167 Whole genome mRNA expression profiling identified nicoti

168 uinolone susceptibility were determined from whole genome sequences.

169 Whole genome sequencing (WGS) was performed to produce a

170 Whole genome sequencing data were analyzed for rare pLoF

171 tifies causative variants in whole exome and whole genome sequencing datasets and provides a powerful

172 mportance and power of strain validation and whole genome sequencing in this context.

173 De novo assembly of whole genome shotgun (WGS) next-generation sequencing (N

174 The availability of whole genome, proteome and transcriptome data has the po

175 ies now generate ROIs distributed across the whole genome.

176 However, current whole-genome amplification (WGA) methods are limited by

177 s limited by the sequence read length during whole-genome analysis.

178 we derive epigenetic energy landscapes from whole-genome bisulfite sequencing (WGBS) data that enabl

179 We used whole-genome bisulfite sequencing in a mouse model with

180 Whole-genome bisulfite sequencing was conducted to asses

181 ist Genome Reference Panel (AGRP), the first whole-genome catalogue of variants and phased haplotypes

182 Whole-genome comparison of pretreatment and relapse isol

183 polymorphism (SNP) genotyping and then with whole-genome data and show how an understanding of evolu

184 also construct de novo linkage maps on 7-12x whole-genome data on the Red postman butterfly (Heliconi

185 Here we exploit representative whole-genome data sets from six diverse bacterial specie

186 ascertainment of data-driven biomarkers from whole-genome data.

187 Our results illustrate the power of whole-genome de novo sequencing relative to resequencing

188 ring time has been shaped by the most recent whole-genome duplication, which suggests that ancient pa

189 latory landscape following hybridization and whole-genome duplication.

190 lite, 4'-OH-2,5-DCB, was then examined using whole-genome expression microarrays (Affymetrix).

191 A related future application for GeneImp is whole-genome imputation based on the off-target reads fr

192 ation-independent mutational spectrum at the whole-genome level of a clonally aged population and unc

193 ental populations of Escherichia coli, using whole-genome metagenomic sequencing at five hundred-gene

194 The whole-genome mutation landscape of melanoma reveals dive

195 BAC-end sequences (BES) to produce a de novo whole-genome physical map.

196 enous DNA (15-46%) of sufficient quality for whole-genome reconstruction.

197 Such method consists of fitting whole-genome regression models by subsampling observatio

198 several different cell lineages and present whole-genome replication timing profiles from cells in e

199 Here we combine linkage analysis with whole-genome resequencing in patients with growth hormon

200 From whole-genome resequencing of 292 Cajanus accessions enco

201 Whole-genome RNA sequencing uncovers novel miR-141-regul

202 tively slow, prohibiting applications on the whole-genome scale.

203 We analyzed whole-genome sequence data from families affected by Alz

204 A whole-genome sequence signature analysis identified 3 am

205 Whole-genome sequences of representative highly pathogen

206 Specifically, we utilize 7,444 whole-genome sequences to examine the effect of variants

207 Here we use whole-genome sequences to examine the origin and adaptat

208 ciated with these outbreaks were analyzed by whole-genome sequencing (WGS) analysis.

209 le X syndrome, is challenging for short-read whole-genome sequencing (WGS) data.

210 robiology laboratories underwent culture and whole-genome sequencing (WGS), using WGS to identify tox

211 tection, and outbreak investigation by using whole-genome sequencing (WGS).

212 We used whole-genome sequencing and phylogenetic analysis to inv

213 Here using a large whole-genome sequencing data bank, cancer registry and c

214 105X mean physical coverage and linked-read whole-genome sequencing from 10X Genomics, we document s

215 To address this issue, we carried out 60x whole-genome sequencing of 26 metastases from four patie

216 Here, we show whole-genome sequencing of DNA and RNA in 94 Chinese ind

217 We further performed whole-genome sequencing of nosocomial MDRPa strains to e

218 Whole-genome sequencing of pathogens from host samples b

219 applied molecular genetics, proteomics, and whole-genome sequencing to demonstrate that the MMAR_003

220 Shallow whole-genome sequencing was performed on an Illumina pla

221 Whole-genome sequencing was performed on isolates from c

222 y of data types, including exome sequencing, whole-genome sequencing, RNA-seq, ChIP-seq, targeted seq

223 We performed whole-genome sequencing, structural modelling and cytoge

224 hIP-seq, targeted sequencing and single-cell whole-genome sequencing, with a minimal requirement for

225 and we characterized this interaction using whole-genome sequencing.

226 eight drugs, confirmatory Wayne's assay, and whole-genome sequencing.

227 We provide evidence for a whole-genome triplication event specific but basal to th

228 human tissues by using combined analyses of whole genomes and multi-tissue RNA-sequencing data from

229 We sequenced whole genomes or a panel of 365 genes on 299 samples fro

230 applying a machine learning technique to SP whole genomes.

231 om patients and xenograft models) laden with whole genomic mtDNA as a mediator of this phenotype.

232 natives to wheat and corn as ingredients for whole grain and gluten-free products.

233 omposition and physicochemical properties of whole grain flour from 7 quinoa samples have been analyz

234 udies suggest an inverse association between whole-grain (WG) consumption and inflammation.

235 ncreasing intake (for each daily serving) of whole grains (RR: 0.92; 95% CI: 0.89, 0.95), vegetables

236 was found only for the intake of alcohol and whole grains in relation to colorectal cancer risk.

237 ic diseases: fruits, vegetables, nuts/seeds, whole grains, unprocessed red meats, processed meats, su

238 Although whole gut irradiation with these doses caused lethal GI

239 ral lineage, and therefore retroviruses as a whole, have an ancient marine origin and originated toge

240 15 were 5.7 Gy for whole lung and 4.4 Gy for whole heart.

241 and coronary CT angiography performed with a whole-heart CT scanner.

242 mutant also exhibited decreased survival in whole human blood due to phagocytosis.

243 numbers of intact neutrophils throughout the whole infection site.

244 rt to depend strongly on the category of the whole input.

245 ved within the gene expression profiles from whole kidney biopsies of patients with SLE.

246 add to a core TRM, broadly found across the whole landscape of CRMs, to discriminate promoters from

247 e bouts of elongation and contraction of the whole leech body.

248 Purpose To investigate whether whole-liver enhancing tumor burden [ETB] can serve as an

249 ublished during 2010 to 2015 were 5.7 Gy for whole lung and 4.4 Gy for whole heart.

250 uses precast gelatin-based molds in which a whole mouse brain is embedded, flash frozen, and cryosec

251 sis, we performed transcriptome profiling on whole mouse embryos.

252 c Region (NPR) and successfully retrieved 19 whole mtDNA genomes.

253 Computer simulations of species-specific whole-muscle models indicate that maximum dynamic force

254 From whole organ to single fibre levels, experimental demands

255 p between cell/tissue-scale regeneration and whole organ-scale technology needed to treat intestinal

256 By using the whole-organism C. elegans coupled with versatile biochem

257 aria vaccine continues, the development of a whole-organism vaccine is now receiving much scrutiny.

258 as fluorescent biomarker for Al(3+) in live whole organisms.

259 Finally, whole OSPW also impaired the ability of RAW 264.7 cells

260 of inorganic and organic components found in whole OSPW are acutely toxic at much lower doses than we

261 64.7 mouse macrophage cell line we show that whole OSPW containing naphthenic acid (NA) concentration

262 ur between the various components present in whole OSPW.

263 onstructs for expression and purification of whole pathways.

264 beling (VSASL) and 3D image acquisition with whole-placenta coverage.

265 ork flow to analyze the capacity of both the whole plant and individual leaves to cope with excess ex

266 ociated with TRV and microalbuminuria in the whole population and with leg ulcers in SS-Sbeta(0) adul

267 nal human studies indicate that although the whole population is intermittently exposed, some individ

268 betasubunit of casein kinase 2, shifted the whole population toward a faster speed and lower contrac

269 s more energy-intense than the hospital as a whole, primarily due to heating, ventilation, and air co

270 Previously we reported a whole protein water-to-bilayer hydrophobicity scale usin

271 ing protein cross-links using non-restricted whole proteome databases.

272 A whole proteome screen identified Mycobacterium tuberculo

273 nantiomeric excess (ee) of D-cysteine in the whole range of ee values (from -100% to 100%).

274 Imaging in whole rat hearts indicated mitochondrial network formati

275 pital regions (beta = -0.15, P = .03) in the whole sample and the occipital regions (beta = -0.21, P

276 d models controlling for relatedness for the whole sample as well as stratified by sex.

277 ssue microarrays (TMA: n = 208 patients) and whole sections (WS: n = 99 patients), TF was associated

278 Dependence of cell cultures on "whole serum" must be examined carefully along with other

279 RNA-seq analysis of whole skin identified a larger number of psoriasis-incre

280 en-source solution for digital pathology and whole slide image analysis.

281 allow users to select regions of interest in whole slide tissue images, run a segmentation pipeline o

282 lanin volume of the anterior, posterior, and whole SNpc correlated with Unified Parkinson's Disease R

283 d to first-line treatment (Cohen's d=0.9191 (whole striatum), 0.7781 (associative striatum), 1.0344 (

284 rgodicity in the fast dynamics can drive the whole system to equilibrium.

285 S) emphasizes the importance of modeling the whole system to understand the controlling factors gover

286 or CD73(-/-) mice received a single dose of whole thorax irradiation (WTI, 15 Gy).

287 nchial epithelial cultures (HBECs) to air or whole tobacco smoke from cigarettes vs. LCs.

288 Since the success of whole tooth bioengineering is predicated on the availabi

289 The performed comparison of the whole transcriptome profile in isolated fibres and other

290 r2(RFP/-) mutant mouse embryos and performed whole transcriptome RNA sequencing analyses.

291 Whole-transcriptome gene expression analyses on WNT-depe

292 processing thousands of individual cells for whole-transcriptome or genomic analysis in a massively p

293 ration of protein data with existing matched whole-transcriptome sequencing (RNA-seq) from the BrainS

294 We performed a whole-transcriptomic analysis of blood samples from Mali

295 eaf senescence and partial canopy dieback to whole-tree mortality reduce canopy leaf area during the

296 ccentricities rather than uniformly over the whole visual field, with a transiently enhanced contribu

297 Whole wheat flour, dough, and bread did not show any TIA

298 and lipid-bound antioxidants, obtained from whole wheat, soybean and olive oil products, respectivel

299 f this study was the shelf life extension of whole-wheat breadsticks through the addition of a rosema

300 to advance the obesity-microbiome field as a whole, with particular emphasis on the development of mi