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1  health effects of chronic coffee intake are wide ranging.
2 ows the matrix and alkali concentrations are wide-ranging.
3 naling that not only clarify the complex and wide ranging actions of S1P but also guide the developme
4 icts that the diffuse risk cues generated by wide-ranging, active predators should induce prey behavi
5 oups to adopt complex structures and perform wide-ranging activities.
6                                              Wide-ranging adverse clinical events can seriously confo
7 e polymorphism of the KIR and HLA loci, with wide-ranging affinities for individual KIR and HLA allel
8                   MHS muscle therefore has a wide-ranging alteration in glucose metabolism: high [Ca(
9 uring two seasonal month-long campaigns with wide-ranging ambient temperatures (-19 to +30 degrees C)
10 nal Classification confirmed the presence of wide-ranging AMD-like pathologic changes even in those w
11 erse sequelae of adolescent cannabis use are wide ranging and extend into young adulthood.
12                                          The wide-ranging and detailed insight informs the design of
13 morpha) [6-8], are among the most temporally wide-ranging and environmentally tolerant members of the
14                These examples illustrate the wide-ranging and fundamental materials physics that can
15                       We also predicted that wide-ranging and migratory behaviours could increase inf
16 th consequences of conflict and violence are wide-ranging and pervasive.
17 at CRISPR mutagenesis in corals should allow wide-ranging and rigorous tests of gene function in both
18 a has declined 29% in total since 1991, with wide-ranging and severe ecological and economic conseque
19 or many species, particularly those that are wide-ranging and sparse.
20                               The issues are wide ranging, and until they are adequately addressed, t
21  wild dogs (Lycaon pictus) are exceptionally wide-ranging, and recolonization is an important element
22      Roadways pose challenges for conserving wide-ranging animal species.
23 ult in positive population outcomes even for wide ranging animals like albatrosses where influencing
24  yet estimating energetic costs in free- and wide-ranging animals presents a significant challenge.
25 hat seaweed-affiliated bacterial flora had a wide-ranging antibacterial activities and potential natu
26 processes underpinning this unusual enzyme's wide-ranging antiviral activity.
27 is live-cell mRNA imaging approach will have wide ranging application wherever heterogeneity plays an
28 ng and assembly methods that would allow for wide-ranging application of whole-genome analysis.
29                          Stentrodes may have wide ranging applications as a neural interface for trea
30                          The DTIA method has wide ranging applications for addressing fundamental pro
31 ineering light-sensitivity into proteins has wide ranging applications in molecular studies and neuro
32                                          The wide ranging applications of fluorine in drug design are
33                                          The wide-ranging applications and versatility of these imida
34 ultiple nuclear species in bulk matter, with wide-ranging applications from basic physics and chemist
35 f CRISPR-Cas biotechnological toolkits, with wide-ranging applications from genome editing to diagnos
36 ) becomes more prevalent, this problem finds wide-ranging applications in areas as varied as biodiver
37 izing integrated optical meta-circuits, with wide-ranging applications in areas from imaging and sens
38 ose digestion, and microbial symbiosis) with wide-ranging applications in diverse biotechnological ni
39 e novel system provides a promising tool for wide-ranging applications in mechanistic research of WAT
40 ate of causal influence; thus, we anticipate wide-ranging applications in neuroscience and beyond.
41 losed-cell stochastic elastomeric foams have wide-ranging applications in numerous industries: from t
42 racold polyatomic molecules have potentially wide-ranging applications in quantum simulation and comp
43 s inherently complex and broad in scope with wide-ranging applications in the biology, chemistry, mat
44 n depth << pair plasma size, which will have wide-ranging applications to astrophysics and fundamenta
45  these hierarchical microshells suitable for wide-ranging applications, including biological ones.
46  operating in low-light-level conditions has wide-ranging applications, spanning biological imaging t
47           This integrated approach will have wide-ranging applications, such as in deep lineage traci
48 f piggyBac transposase that have potentially wide-ranging applications, such as reversible transgenes
49 serve as a diverse and tunable feedstock for wide-ranging applications.
50 e-semiconductor compatible silicon chips for wide-ranging applications.
51 ntly used tests are not sensitive enough for wide-ranging applications.
52 ials are a highly studied field due to their wide-ranging applications; however, only a small group o
53 amount of research has centered on Ref-1, no wide-ranging approach had been performed on the effects
54                The findings enable sEMG from wide ranging areas of the body.
55 imprinted genes influence an extraordinarily wide-ranging array of biological processes, the effects
56  the current 'myocentric' paradigm given the wide-ranging array of impacts that exercise exerts on at
57 nts", which enable in principle control over wide-ranging aspects of reactivity and structure.
58 been implicated in the pathogenesis, support wide-ranging benefits from proof-of-concept studies in M
59                                    Given the wide-ranging benefits of breastfeeding, and the low prev
60 iabetes increases HIF-1alpha protein and has wide-ranging benefits, some of which are at least partia
61 rn (Hippophae rhamnoides, SB) leaves contain wide-ranging bioactive compounds.
62 talytic activity of proteolytic enzymes with wide ranging biological functions.
63      Zinc is an essential trace element with wide-ranging biological functions, whereas the Hedgehog
64 d of organic or inorganic materials and have wide-ranging biological roles.
65 his had led to a multitude of complexes with wide-ranging biomedical applications.
66                      We thus demonstrate the wide-ranging biomedical utilities of PLC-derived organoi
67 derstanding this process is essential if the wide-ranging biotechnological applications of methanotro
68 l correlate of Francis's intellectual world: wide-ranging, brilliantly lit, a little overawing, but a
69 pithecus and extinct and extant hominids are wide ranging but difficult to substantiate because of it
70  consist of several classes of RNA that have wide-ranging but often poorly described functions and th
71                                          Her wide-ranging career began with the study of protein fold
72                                    Globally, wide-ranging carnivore populations are imperiled due to
73  posttranslational modification that impacts wide-ranging cellular functions, including transcription
74 to multiple inputs, serving as the basis for wide-ranging cellular functions.
75 astoma cells overexpress BORIS, resulting in wide-ranging changes in chromatin interaction and transc
76 obe epilepsy is associated with large-scale, wide-ranging changes in gene expression in the hippocamp
77 xication, and is associated with persistent, wide-ranging changes in gene expression within the media
78 campus that are associated with large-scale, wide-ranging changes in gene expression.
79 icles on radical SAM enzymes that accomplish wide-ranging chemical transformations.
80 ibility of synthesizing anisotropic dyes and wide ranging choice of liquid crystals nonlinear optical
81  exhibit different cell-cycle lifestyles and wide-ranging chromosome copy numbers, fluctuating from 1
82                                        These wide-ranging circulating biomarkers show an association
83 ion by neutrophils likely has a significant, wide ranging clinical impact.
84  are now being reviewed to reflect these new wide-ranging clinical and radiological findings.
85                    Monogenic epilepsies with wide-ranging clinical severity have been associated with
86                    The frontal lobes control wide-ranging cognitive functions; however, functional su
87 n our thinking when seeking solutions to the wide-ranging complications which face the transplant tea
88 .3%-11.2%) compared to older varieties under wide-ranging conditions.
89 w a single amino acid mutation may have such wide ranging consequences.
90 ies have demonstrated that loss of ABCG1 has wide-ranging consequences and impacts lymphocyte and ste
91 i in the co-cultures, thus demonstrating the wide-ranging consequences of inter-species interactions
92 tion of intergenic fusions and highlight the wide-ranging consequences of structural rearrangements i
93 t two decades, sentinel testing has revealed wide-ranging contamination rates in mammalian culture.
94 ing molecules GSNO and SNO-CoA, allowing for wide-ranging control of protein S-nitrosylation under bo
95              These findings demonstrate that wide-ranging cortical feedback operates at an earlier st
96 rotein kinase or phosphatase family can have wide-ranging deleterious effects in both metazoans and p
97 dividual differences in social interest have wide-ranging developmental consequences, impacting infan
98  and protozoa (i.e. microparasites) most for wide-ranging, dietary generalist host species.
99 e?" In a productive 2-day meeting, there was wide-ranging discussion on a broad series of topics, res
100                                            A wide-ranging discussion on the best approaches to allow
101 factors of interest in scales with multiple, wide-ranging domains.
102         Overall, this review illustrates the wide-ranging effect of IFN-gamma on the (patho-)physiolo
103   Ethylene is a gas and a plant hormone with wide ranging effects and a well defined signaling pathwa
104 ations in the cellular microenvironment have wide ranging effects on resultant tissue type.
105 ved through multiple sensory modalities with wide-ranging effects across multiple brain areas to impr
106 hatase nonreceptor type 22 gene, PTPN22, has wide-ranging effects in immune cells including suppressi
107                           The model revealed wide-ranging effects of AES on innate and adaptive immun
108 important because ipRGCs mediate many of the wide-ranging effects of short-wavelength light on human
109                          The significant and wide-ranging effects of these immunotherapies have promp
110 ocorticoid hormone cortisol is known to have wide-ranging effects on a variety of physiological syste
111 iolet radiation is a pervasive stimulus with wide-ranging effects on all living forms.
112 al lymphopoietin (TSLP) is now known to have wide-ranging effects on both hematopoietic and nonhemato
113 nd exposure time, high-temperature water has wide-ranging effects on both the surface roughness and t
114 ode secreted proteins that have profound and wide-ranging effects on cellular metabolism.
115                     Ki-67 silencing also had wide-ranging effects on chromatin organisation, disrupti
116 iological role of p63 is quite complex, with wide-ranging effects on development, differentiation, an
117 nges in the expression of one miRNA can have wide-ranging effects on diverse cellular processes assoc
118                         What underlies their wide-ranging effects on genome stability remains poorly
119      Changes in resident microbiota may have wide-ranging effects on human health.
120              Lysophosphatidic acid (LPA) has wide-ranging effects on many different cell types, actin
121                                   They exert wide-ranging effects on synaptic signaling and plasticit
122 , substitutions at rheostat position 267 had wide-ranging effects on the phenotype of this integral m
123 vealed that the sigA(G336C) substitution has wide-ranging effects, including elevated expression of t
124                     Effects of zolpidem were wide ranging (eg, improvement on the JFK Coma Recovery S
125 mophores with diverse electronic spectra and wide-ranging emission intensities.
126 rom 2008-2016, the southern populations of a wide-ranging endemic amphibian (the California newt, Tar
127 ukaryotic adaptation pathways operate within wide-ranging environmental conditions without stimulus s
128      Results for the 35 analysed animals are wide-ranging, especially in terms of strontium (0.707-0.
129 activated sorting techniques has resulted in wide-ranging estimates, which may be the result of conte
130 l conditions associated with this feature is wide-ranging even if never discussed in detail.
131                              Animals display wide-ranging evolutionary adaptations based on their eco
132 al intersexual antagonistic coevolution with wide-ranging evolutionary consequences.
133 astomosis visualization among reviewers with wide-ranging experience.
134 nsciousness into components that account for wide ranging experiences, from the simplest sensory expe
135 hich embody his philosophies of life and his wide-ranging experiences and interests.
136  domesticated for host needs, reflecting the wide-ranging exploitation of any and all available DNA s
137                                              Wide-ranging exploration of analogues of an ATP-competit
138                                              Wide-ranging exploration of potential replacements for a
139 ability and scalp potentials, we conducted a wide-ranging exploratory data analysis (EDA), pooling ou
140                                              Wide-ranging field evidence indicates that methane seepa
141 ological cells is fundamentally important to wide-ranging fields from nanotoxicology to drug delivery
142 evidence suggests that sharks must engage in wide-ranging foraging excursions to meet energy needs [9
143                      Therapeutic proteins of wide-ranging function hold great promise for treating di
144 component of the Microprocessor complex with wide-ranging functional consequences.
145 ctures with desired chiroptical response for wide-ranging functionalities and applications by bottom-
146                A large number of genes, with wide ranging functions, are implicated in its aetiology,
147 amine neurons is regulated and underlies the wide-ranging functions that have been attributed to dopa
148 r suppressor p53 controls transcription of a wide-ranging gene network involved in apoptosis, cell cy
149                                  Systematic, wide-ranging genetic screening should be offered in pES;
150 ilability of their prey, a foraging shift in wide-ranging Hawaiian petrel populations suggests a rela
151 physical activity levels are associated with wide-ranging health benefits, disease prevention, and lo
152 n the Myelin Protein Zero (Mpz) gene produce wide-ranging hereditary neuropathy phenotypes.
153 to complex heteroarylated phenol moieties by wide-ranging heterocyclic scaffolds.
154 ween residual entropy and viscosity based on wide-ranging, highly accurate experimental and simulatio
155                   We find this pattern to be wide ranging, holding for large and small synapses in th
156 endence on ion chemistry and charge, despite wide-ranging hydration energies and the membrane's dipol
157 rvation and their relevance to assessing the wide-ranging impact of fisheries and climate change on m
158                    Our results highlight the wide-ranging impact of sSNPs, which invert the programme
159 ximal oxygen uptake, VO2 max ), a trait with wide-ranging impact on health and performance indicators
160 esults support the idea that ageing has more wide-ranging impact on reproductive behaviours than does
161 both humans and crops-can have immediate and wide-ranging impacts on diversity that conflict with exp
162                     Novel parasites can have wide-ranging impacts, not only on host populations, but
163 ate-linked bottom-up mechanisms and may have wide ranging implications for alpine ecosystems.
164  cells and we believe that our findings have wide ranging implications for the entire cannabinoid fie
165                                Chirality has wide ranging implications from medical physics to cosmol
166 ify cells and organisms almost at will, with wide-ranging implications across biology and medicine.
167                          These findings have wide-ranging implications because this study was designe
168 cine but has broad biological relevance with wide-ranging implications for a diverse array of species
169                                  Despite its wide-ranging implications for biology and conservation,
170 ithin drug design and the finding might have wide-ranging implications for drug design.
171                             The results have wide-ranging implications for global ecology and for ant
172                            Our findings have wide-ranging implications for health services and for ex
173               Transgenerational effects have wide-ranging implications for human health, biological a
174 ith loss of ATP13A2 function that could have wide-ranging implications for it as a therapeutic target
175                             Our results have wide-ranging implications for optimising antitrypanosoma
176                                     This has wide-ranging implications for our ability to quantitativ
177                     Rapid climate change has wide-ranging implications for the Arctic region, includi
178             The findings presented here have wide-ranging implications for the design and interpretat
179 er otherwise constant conditions, could have wide-ranging implications for the future development of
180 ceptors on basolateral nucleus efferents has wide-ranging implications for the numerous deleterious s
181  and galactic cosmic rays at tens of TeV has wide-ranging implications for the structure of our helio
182 n base editors (C*G->T*A and A*T->G*C), with wide-ranging implications for treating many human geneti
183                           These results have wide-ranging implications for understanding reactive tra
184             We propose that our results have wide-ranging implications for understanding the biology
185 arasite community diversity and turnover has wide-ranging implications for understanding the selectiv
186 molecules for treatment of SMA, our work has wide-ranging implications in understanding how small mol
187 Recent genomic studies are investigating the wide-ranging implications of malaria complex infections
188                                          The wide-ranging implications of the work are discussed, and
189 of 'Making Sense of Stress', this review has wide-ranging implications that are not limited to one di
190 nt advance in cell biology, with potentially wide-ranging implications, but it seems premature to con
191      A laboratory's programming language has wide-ranging implications.
192  to approximate the effects of policies with wide-ranging implications.
193 r condensate involved in DNA replication has wide-ranging implications.
194  targeted cohesin loading, a phenomenon with wide-ranging importance in chromosome segregation and, i
195 a phage resistance phenotype, suggesting the wide-ranging importance of the host methionine aminopept
196                                          The wide-ranging improvements reflect the convergence of P2R
197                  Although these diseases are wide ranging in their clinical manifestations, each can
198 e potential applications of such efforts are wide ranging, including the generation of fuels, chemica
199     Urinary control of SCN activity exhibits wide ranging individual differences.
200                                  Despite the wide-ranging influence of ubiquitin in endosomal process
201                            Their potentially wide-ranging influence on disease phenotype also suggest
202            These GABAergic neurons integrate wide-ranging inputs and innervate multiple arousal-promo
203 he research and bioethics communities lead a wide-ranging inquiry aimed at mapping out solutions to t
204 natural and synthetic crystals is a topic of wide-ranging interest owing to its relevance in fields s
205 mer's disease (AD) pathogenesis and inspired wide-ranging investigations into the underlying mechanis
206  conductive MthK structures were obtained in wide-ranging K(+) concentrations (6 to 150 mM), unlike K
207 ble collection of achievements that covers a wide ranging landscape of molecular complexity and diver
208 for pumas (Puma concolor) and other cryptic, wide-ranging large carnivores is challenging.
209 s to be recognized in conservation plans for wide-ranging, large-bodied species, minimal ecological r
210                        Our findings indicate wide ranging LC50 24 h postfertilization values (0.487 p
211  known to adapt to environments that contain wide-ranging levels of chemoattractant.
212 d distinct symptom profiles characterized by wide-ranging levels of severity.
213                                            A wide-ranging literature review using targeted medical su
214 g season from 2013 to 2063, which results in wide-ranging magnitudes of effects across guilds and fun
215               Management and conservation of wide-ranging mammals will depend on holistic strategies
216  photolysis in the NMR probe, resulting in a wide-ranging map of kinetic selectivities.
217 hat the population dynamics of a long-lived, wide-ranging marine predator are associated with changes
218                     These findings suggest a wide-ranging mechanism by which direct interaction of Gb
219 Rs (Acrs), that block Cas enzyme function by wide-ranging mechanisms.
220                 We provide evidence that the wide-ranging melting temperatures of zeolitic MOFs are r
221          Tie2 expression declined rapidly in wide-ranging models of leak-associated infections, inclu
222             This computational approach uses wide-ranging naturalistic stimuli and open-ended statist
223   Autism spectrum disorder (ASD) encompasses wide-ranging neuropsychiatric symptoms with unclear etio
224 sticity because they are a highly adaptable, wide-ranging omnivore.
225         The Center for Disease Control (CDC) Wide-ranging Online Data for Epidemiologic Research (WON
226 for Disease Control and Prevention's Control Wide-Ranging Online Data for Epidemiologic Research data
227 e Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research data
228 Centers for Disease Control and Prevention's Wide-ranging Online Data for Epidemiologic Research data
229 S Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research onli
230 Centers for Disease Control and Prevention's Wide-Ranging Online Data for Epidemiologic Research to c
231 spherical particles and hence disregards the wide-ranging particle shapes occurring in nature, such a
232 ng exploration of toxicity to organisms from wide-ranging parts of the ecosystem food webs.
233 oup A Streptococcus, GAS) is responsible for wide-ranging pathologies at numerous sites in the body b
234 ensal microbiota, which can be influenced by wide-ranging pharmacologic interventions.
235                                 Finally, the wide-ranging phenotypes that result from loss of functio
236 antial excited-state oxidation potential for wide-ranging photochemistry--highlighted by the ability
237                              However, due to wide-ranging physicochemical diversity, characterizing t
238 ytoplasmic mRNAs, but how m(6)A achieves its wide-ranging physiological role needs further exploratio
239 /suburban, agricultural and/or forested) and wide ranging population densities.
240 redictive map of population density revealed wide-ranging potential for an invasive large mammal to e
241                         Here, we discuss the wide-ranging potential of gas-fuels to revolutionize the
242  arrayed label-free platform illustrates the wide-ranging potential of high-dimensionality artificial
243  of two-dimensional (2D) semiconductors with wide-ranging practical applications.
244                 Most surprising has been the wide-ranging presentation of clinical manifestations in
245   The biological carbon pump (BCP) comprises wide-ranging processes that set carbon supply, consumpti
246 ts disruption has since been found to affect wide-ranging processes, including protein trafficking, o
247  machines is matched to their roles in these wide-ranging processes.
248 on or triplication of Xq28 causes an equally wide-ranging progressive neurological disorder, MECP2 du
249 e United States through 2030 on the basis of wide-ranging projections of population obesity and ESRD
250                                          The wide-ranging properties of KIR allotypes arise from subs
251  concepts in high-energy physics, leading to wide-ranging protected properties in transport and spect
252 Moreover, the experimental heterogeneity and wide-ranging quality of high-throughput biological data
253 ced professionals who have worked to achieve wide-ranging reforms dedicated to preserving life, prote
254 mble to keep up with the frequent release of wide-ranging regulations.
255  IO subnuclei are inhibited by synapses with wide ranging release kinetics.
256 ides a critical new service that facilitates wide-ranging research interests.
257 ip between a predator and its prey can cause wide-ranging ripple effects through ecosystems, includin
258 m for GIGANTEA activity that can explain its wide-ranging role in plant biology.The plant-specific GI
259 together, these findings suggest diverse and wide-ranging roles for tRFs and highlight the extensive
260          The 14-3-3 protein hub, which plays wide-ranging roles in cellular processes, has been linke
261 atic species, suggesting that A. simus was a wide-ranging scavenger utilizing terrestrial and marine
262 ray matter components of the human brain has wide-ranging scientific and clinical applications.
263                                      Despite wide-ranging scientific and popular impact, independent
264 he known interaction between fisheries and a wide-ranging seabird, the Northern gannet Morus bassanus
265  implementing conservation policies by using wide-ranging seabirds to patrol oceans.
266 ve correction for potential confounding, and wide-ranging sensitivity analyses.
267 patterns that comprise natural sounds across wide-ranging sensory contexts.
268 Herein, using a unique polymer family with a wide-ranging set of cationic and hydrophobic features, w
269 ers intrinsic resistance to TKI therapy in a wide-ranging set of leukemias, and might represent a uni
270 ariation proves significant to a generalist, wide-ranging species, at the slow end of the slow-fast c
271                   However, for inconspicuous wide-ranging species, births may be missed and fecundity
272 of migratory connectivity for highly-mobile, wide-ranging species, such as sea turtles, is challengin
273 llow high-risk hotspots to be identified for wide-ranging species.
274 ot only of pulmonary fibrosis, but also of a wide-ranging spectrum of chronic disorders.
275 nes macrophages (Mphi) as plastic cells with wide-ranging states of activation and expression of diff
276 n-pairing catalysis was demonstrated to be a wide-ranging strategy that can utilize a variety of cati
277  neurons is strongly influenced by spatially wide-ranging surround suppression in a manner that effec
278 mplex developmental disorder associated with wide-ranging symptoms, including mental retardation, spe
279 duction of a diverse array of compounds with wide-ranging synthesis requirements, alongside synthesis
280                                           In wide-ranging taxa with historically dynamic ranges, past
281  evaluating alternate refugial scenarios for wide-ranging taxa.
282 ilms and polymer-nanocrystal composites with wide-ranging technological applications.
283 crete orientations of light and are found in wide-ranging technologies, from windows and glasses to c
284 ed for suspected preeclampsia (n = 1888) had wide-ranging test accuracy (sensitivity, 22%-100%; speci
285 e deepest unsolved problems in science, with wide-ranging theoretical, clinical, and ethical implicat
286 sed vectors are of increasing importance for wide ranging therapeutic applications.
287 sely allied with host evolution, even across wide-ranging timescales and diverse animal systems reare
288 s they will have to physiologically straddle wide-ranging timescales in the alteration of ocean condi
289 cardiac M2-like macrophages highly expressed wide-ranging tissue repair-related genes.
290  properties of intense light is important in wide-ranging topics at the forefront of extreme light-ma
291 ata provides a roadmap for interrogating the wide-ranging toxicity data in the literature and suggest
292 t KRAS protein are potentially important for wide-ranging tumour therapy.
293 ly Next-Generation Sequencing has identified wide-ranging usage with highly diverse and unique repert
294 -38.3 degrees ) demonstrates a potential for wide-ranging use.
295                 Synthetic gene networks have wide-ranging uses in reprogramming and rewiring organism
296 PCR (qPCR) that promote assay robustness and wide-ranging utility are not readily applied in dPCR.
297 a revolutionary gene editing technology with wide-ranging utility.
298 nternational Humic Substance Society (IHSS), wide-ranging values exist in the literature.
299 dual exploration-exploitation strategy using wide ranging wandering albatrosses (Diomedea exulans) as
300                            Here, we used the wide-ranging wandering albatross Diomedea exulans to inv

 
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